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Mireia Sole; Joan Blanco; Debora Gil; G. Fonseka; Richard Frodsham; Francesca Vidal; Zaida Sarrate |
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Noves perspectives en l estudi de la territorialitat cromosomica de cel·lules germinals masculines: estudis tridimensionals |
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2017 |
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Biologia de la Reproduccio |
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JBR |
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15 |
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73-78 |
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In somatic cells, chromosomes occupy specific nuclear regions called chromosome territories which are involved in the
maintenance and regulation of the genome. Preliminary data in male germ cells also suggest the importance of chromosome
territoriality in cell functionality. Nevertheless, the specific characteristics of testicular tissue (presence of different
cell types with different morphological characteristics, in different stages of development and with different ploidy)
makes difficult to achieve conclusive results. In this study we have developed a methodology to approach the threedimensional
study of all chromosome territories in male germ cells from C57BL/6J mice (Mus musculus). The method
includes the following steps: i) Optimized cell fixation to obtain an optimal preservation of the three-dimensionality cell
morphology, ii) Chromosome identification by FISH (Chromoprobe Multiprobe® OctoChrome™ Murine System; Cytocell)
and confocal microscopy (TCS-SP5, Leica Microsystems), iii) Cell type identification by immunofluorescence
iv) Image analysis using Matlab scripts, v) Numerical data extraction related to chromosome features, chromosome
radial position and chromosome relative position. This methodology allows the unequivocally identification and the
analysis of the chromosome territories of all spermatogenic stages. Results will provide information about the features
that determine chromosomal position, preferred associations between chromosomes, and the relationship between chromosome
positioning and genome regulation. |
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978-84-697-3767-5 |
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IAM; 600.096; 600.145 |
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Admin @ si @ SBG2017c |
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2961 |
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Author |
Esmitt Ramirez; Carles Sanchez; Agnes Borras; Marta Diez-Ferrer; Antoni Rosell; Debora Gil |
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BronchoX: bronchoscopy exploration software for biopsy intervention planning |
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2018 |
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Healthcare Technology Letters |
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HTL |
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5 |
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5 |
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177–182 |
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Virtual bronchoscopy (VB) is a non-invasive exploration tool for intervention planning and navigation of possible pulmonary lesions (PLs). A VB software involves the location of a PL and the calculation of a route, starting from the trachea, to reach it. The selection of a VB software might be a complex process, and there is no consensus in the community of medical software developers in which is the best-suited system to use or framework to choose. The authors present Bronchoscopy Exploration (BronchoX), a VB software to plan biopsy interventions that generate physician-readable instructions to reach the PLs. The authors’ solution is open source, multiplatform, and extensible for future functionalities, designed by their multidisciplinary research and development group. BronchoX is a compound of different algorithms for segmentation, visualisation, and navigation of the respiratory tract. Performed results are a focus on the test the effectiveness of their proposal as an exploration software, also to measure its accuracy as a guiding system to reach PLs. Then, 40 different virtual planning paths were created to guide physicians until distal bronchioles. These results provide a functional software for BronchoX and demonstrate how following simple instructions is possible to reach distal lesions from the trachea. |
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IAM; 600.096; 600.075; 601.323; 601.337; 600.145 |
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Admin @ si @ RSB2018a |
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3132 |
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Antoni Rosell; Sonia Baeza; S. Garcia-Reina; JL. Mate; Ignasi Guasch; I. Nogueira; I. Garcia-Olive; Guillermo Torres; Carles Sanchez; Debora Gil |
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Radiomics to increase the effectiveness of lung cancer screening programs. Radiolung preliminary results. |
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2022 |
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European Respiratory Journal |
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ERJ |
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60 |
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66 |
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IAM |
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Admin @ si @ RBG2022c |
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3835 |
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Antoni Rosell; Sonia Baeza; S. Garcia-Reina; JL. Mate; Ignasi Guasch; I. Nogueira; I. Garcia-Olive; Guillermo Torres; Carles Sanchez; Debora Gil |
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EP01.05-001 Radiomics to Increase the Effectiveness of Lung Cancer Screening Programs. Radiolung Preliminary Results |
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2022 |
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Journal of Thoracic Oncology |
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JTO |
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17 |
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9 |
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S182 |
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IAM |
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Admin @ si @ RBG2022b |
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3834 |
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Oriol Ramos Terrades; Albert Berenguel; Debora Gil |
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A Flexible Outlier Detector Based on a Topology Given by Graph Communities |
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2022 |
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Big Data Research |
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BDR |
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29 |
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100332 |
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Classification algorithms; Detection algorithms; Description of feature space local structure; Graph communities; Machine learning algorithms; Outlier detectors |
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Outlier detection is essential for optimal performance of machine learning methods and statistical predictive models. Their detection is especially determinant in small sample size unbalanced problems, since in such settings outliers become highly influential and significantly bias models. This particular experimental settings are usual in medical applications, like diagnosis of rare pathologies, outcome of experimental personalized treatments or pandemic emergencies. In contrast to population-based methods, neighborhood based local approaches compute an outlier score from the neighbors of each sample, are simple flexible methods that have the potential to perform well in small sample size unbalanced problems. A main concern of local approaches is the impact that the computation of each sample neighborhood has on the method performance. Most approaches use a distance in the feature space to define a single neighborhood that requires careful selection of several parameters, like the number of neighbors.
This work presents a local approach based on a local measure of the heterogeneity of sample labels in the feature space considered as a topological manifold. Topology is computed using the communities of a weighted graph codifying mutual nearest neighbors in the feature space. This way, we provide with a set of multiple neighborhoods able to describe the structure of complex spaces without parameter fine tuning. The extensive experiments on real-world and synthetic data sets show that our approach outperforms, both, local and global strategies in multi and single view settings. |
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August 28, 2022 |
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DAG; IAM; 600.140; 600.121; 600.139; 600.145; 600.159 |
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Admin @ si @ RBG2022a |
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3718 |
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Miquel Angel Piera; Jose Luis Muñoz; Debora Gil; Gonzalo Martin; Jordi Manzano |
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A Socio-Technical Simulation Model for the Design of the Future Single Pilot Cockpit: An Opportunity to Improve Pilot Performance |
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2022 |
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IEEE Access |
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ACCESS |
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10 |
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22330-22343 |
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Human factors ; Performance evaluation ; Simulation; Sociotechnical systems ; System performance |
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The future deployment of single pilot operations must be supported by new cockpit computer services. Such services require an adaptive context-aware integration of technical functionalities with the concurrent tasks that a pilot must deal with. Advanced artificial intelligence supporting services and improved communication capabilities are the key enabling technologies that will render future cockpits more integrated with the present digitalized air traffic management system. However, an issue in the integration of such technologies is the lack of socio-technical analysis in the design of these teaming mechanisms. A key factor in determining how and when a service support should be provided is the dynamic evolution of pilot workload. This paper investigates how the socio-technical model-based systems engineering approach paves the way for the design of a digital assistant framework by formalizing this workload. The model was validated in an Airbus A-320 cockpit simulator, and the results confirmed the degraded pilot behavioral model and the performance impact according to different contextual flight deck information. This study contributes to practical knowledge for designing human-machine task-sharing systems. |
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Feb 2022 |
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IAM; |
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Admin @ si @ PMG2022 |
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3697 |
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Enric Marti; J.Roncaries; Debora Gil; Aura Hernandez-Sabate; Antoni Gurgui; Ferran Poveda |
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PBL On Line: A proposal for the organization, part-time monitoring and assessment of PBL group activities |
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2015 |
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Journal of Technology and Science Education |
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JOTSE |
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5 |
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2 |
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87-96 |
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IAM; ADAS; 600.076; 600.075 |
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Admin @ si @ MRG2015 |
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2608 |
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Author |
Saad Minhas; Zeba Khanam; Shoaib Ehsan; Klaus McDonald Maier; Aura Hernandez-Sabate |
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Title |
Weather Classification by Utilizing Synthetic Data |
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2022 |
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Sensors |
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SENS |
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22 |
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9 |
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3193 |
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Weather classification; synthetic data; dataset; autonomous car; computer vision; advanced driver assistance systems; deep learning; intelligent transportation systems |
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Weather prediction from real-world images can be termed a complex task when targeting classification using neural networks. Moreover, the number of images throughout the available datasets can contain a huge amount of variance when comparing locations with the weather those images are representing. In this article, the capabilities of a custom built driver simulator are explored specifically to simulate a wide range of weather conditions. Moreover, the performance of a new synthetic dataset generated by the above simulator is also assessed. The results indicate that the use of synthetic datasets in conjunction with real-world datasets can increase the training efficiency of the CNNs by as much as 74%. The article paves a way forward to tackle the persistent problem of bias in vision-based datasets. |
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21 April 2022 |
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MDPI |
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IAM; 600.139; 600.159; 600.166; 600.145; |
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Admin @ si @ MKE2022 |
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3761 |
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Saad Minhas; Aura Hernandez-Sabate; Shoaib Ehsan; Klaus McDonald Maier |
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Title |
Effects of Non-Driving Related Tasks during Self-Driving mode |
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2022 |
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IEEE Transactions on Intelligent Transportation Systems |
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TITS |
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23 |
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2 |
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1391-1399 |
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Perception reaction time and mental workload have proven to be crucial in manual driving. Moreover, in highly automated cars, where most of the research is focusing on Level 4 Autonomous driving, take-over performance is also a key factor when taking road safety into account. This study aims to investigate how the immersion in non-driving related tasks affects the take-over performance of drivers in given scenarios. The paper also highlights the use of virtual simulators to gather efficient data that can be crucial in easing the transition between manual and autonomous driving scenarios. The use of Computer Aided Simulations is of absolute importance in this day and age since the automotive industry is rapidly moving towards Autonomous technology. An experiment comprising of 40 subjects was performed to examine the reaction times of driver and the influence of other variables in the success of take-over performance in highly automated driving under different circumstances within a highway virtual environment. The results reflect the relationship between reaction times under different scenarios that the drivers might face under the circumstances stated above as well as the importance of variables such as velocity in the success on regaining car control after automated driving. The implications of the results acquired are important for understanding the criteria needed for designing Human Machine Interfaces specifically aimed towards automated driving conditions. Understanding the need to keep drivers in the loop during automation, whilst allowing drivers to safely engage in other non-driving related tasks is an important research area which can be aided by the proposed study. |
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Feb. 2022 |
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IAM; 600.139; 600.145 |
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Admin @ si @ MHE2022 |
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3468 |
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H.Martin Kjer; Jens Fagertuna; Sergio Vera; Debora Gil; Miguel Angel Gonzalez Ballester; Rasmus R. Paulsena |
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Free-form image registration of human cochlear uCT data using skeleton similarity as anatomical prior |
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2016 |
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Patter Recognition Letters |
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PRL |
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76 |
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1 |
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76-82 |
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IAM; 600.060 |
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Admin @ si @ MFV2017b |
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2941 |
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