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Author Debora Gil; Jaume Garcia; Ruth Aris; Guillaume Houzeaux; Manuel Vazquez edit   pdf
openurl 
  Title A Riemmanian approach to cardiac fiber architecture modelling Type Conference Article
  Year 2009 Publication 1st International Conference on Mathematical & Computational Biomedical Engineering Abbreviated Journal  
  Volume Issue Pages 59-62  
  Keywords cardiac fiber architecture; diffusion tensor magnetic resonance imaging; differential (Rie- mannian) geometry.  
  Abstract There is general consensus that myocardial fiber architecture should be modelled in order to fully understand the electromechanical properties of the Left Ventricle (LV). Diffusion Tensor magnetic resonance Imaging (DTI) is the reference image modality for rapid measurement of fiber orientations by means of the tensor principal eigenvectors. In this work, we present a mathematical framework for across subject comparison of the local geometry of the LV anatomy including the fiber architecture from the statistical analysis of DTI studies. We use concepts of differential geometry for defining a parametric domain suitable for statistical analysis of a low number of samples. We use Riemannian metrics to define a consistent computation of DTI principal eigenvector modes of variation. Our framework has been applied to build an atlas of the LV fiber architecture from 7 DTI normal canine hearts.  
  Address  
  Corporate Author Thesis  
  Publisher Place of Publication Swansea (UK) Editor Nithiarasu, R.L.R.V.L.  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference CMBE  
  Notes (down) IAM Approved no  
  Call Number IAM @ iam @ FGA2009 Serial 1520  
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Author Debora Gil; Jaume Garcia; Manuel Vazquez; Ruth Aris; Guillaume Houzeaux edit   pdf
url  openurl
  Title Patient-Sensitive Anatomic and Functional 3D Model of the Left Ventricle Function Type Conference Article
  Year 2008 Publication 8th World Congress on Computational Mechanichs (WCCM8)/5th European Congress on Computational Methods in Applied Sciences and Engineering (ECCOMAS 2008) Abbreviated Journal  
  Volume Issue Pages  
  Keywords Left Ventricle; Electromechanical Models; Image Processing; Magnetic Resonance.  
  Abstract Early diagnosis and accurate treatment of Left Ventricle (LV) dysfunction significantly increases the patient survival. Impairment of LV contractility due to cardiovascular diseases is reflected in its motion patterns. Recent advances in medical imaging, such as Magnetic Resonance (MR), have encouraged research on 3D simulation and modelling of the LV dynamics. Most of the existing 3D models consider just the gross anatomy of the LV and restore a truncated ellipse which deforms along the cardiac cycle. The contraction mechanics of any muscle strongly depends on the spatial orientation of its muscular fibers since the motion that the muscle undergoes mainly takes place along the fibers. It follows that such simplified models do not allow evaluation of the heart electro-mechanical function and coupling, which has recently risen as the key point for understanding the LV functionality . In order to thoroughly understand the LV mechanics it is necessary to consider the complete anatomy of the LV given by the orientation of the myocardial fibres in 3D space as described by Torrent Guasp. We propose developing a 3D patient-sensitive model of the LV integrating, for the first time, the ven- tricular band anatomy (fibers orientation), the LV gross anatomy and its functionality. Such model will represent the LV function as a natural consequence of its own ventricular band anatomy. This might be decisive in restoring a proper LV contraction in patients undergoing pace marker treatment. The LV function is defined as soon as the propagation of the contractile electromechanical pulse has been modelled. In our experiments we have used the wave equation for the propagation of the electric pulse. The electromechanical wave moves on the myocardial surface and should have a conductivity tensor oriented along the muscular fibers. Thus, whatever mathematical model for electric pulse propa- gation [4] we consider, the complete anatomy of the LV should be extracted. The LV gross anatomy is obtained by processing multi slice MR images recorded for each patient. Information about the myocardial fibers distribution can only be extracted by Diffusion Tensor Imag- ing (DTI), which can not provide in vivo information for each patient. As a first approach, we have computed an average model of fibers from several DTI studies of canine hearts. This rough anatomy is the input for our electro-mechanical propagation model simulating LV dynamics. The average fiber orientation is updated until the simulated LV motion agrees with the experimental evidence provided by the LV motion observed in tagged MR (TMR) sequences. Experimental LV motion is recovered by applying image processing, differential geometry and interpolation techniques to 2D TMR slices [5]. The pipeline in figure 1 outlines the interaction between simulations and experimental data leading to our patient-tailored model.  
  Address  
  Corporate Author Thesis  
  Publisher Place of Publication Venezia (Italia) Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN B-31470-08 ISBN Medium  
  Area Expedition Conference  
  Notes (down) IAM Approved no  
  Call Number IAM @ iam @ GGV2008c Serial 1521  
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Author Debora Gil; Jaume Garcia; Aura Hernandez-Sabate; Enric Marti edit   pdf
url  doi
openurl 
  Title Manifold parametrization of the left ventricle for a statistical modelling of its complete anatomy Type Conference Article
  Year 2010 Publication 8th Medical Imaging Abbreviated Journal  
  Volume 7623 Issue 762304 Pages 304  
  Keywords  
  Abstract Distortion of Left Ventricle (LV) external anatomy is related to some dysfunctions, such as hypertrophy. The architecture of myocardial fibers determines LV electromechanical activation patterns as well as mechanics. Thus, their joined modelling would allow the design of specific interventions (such as peacemaker implantation and LV remodelling) and therapies (such as resynchronization). On one hand, accurate modelling of external anatomy requires either a dense sampling or a continuous infinite dimensional approach, which requires non-Euclidean statistics. On the other hand, computation of fiber models requires statistics on Riemannian spaces. Most approaches compute separate statistical models for external anatomy and fibers architecture. In this work we propose a general mathematical framework based on differential geometry concepts for computing a statistical model including, both, external and fiber anatomy. Our framework provides a continuous approach to external anatomy supporting standard statistics. We also provide a straightforward formula for the computation of the Riemannian fiber statistics. We have applied our methodology to the computation of complete anatomical atlas of canine hearts from diffusion tensor studies. The orientation of fibers over the average external geometry agrees with the segmental description of orientations reported in the literature.  
  Address  
  Corporate Author Thesis  
  Publisher SPIE Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference SPIE  
  Notes (down) IAM Approved no  
  Call Number IAM @ iam @ GGH2010a Serial 1522  
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Author Debora Gil; Aura Hernandez-Sabate; Mireia Burnat; Steven Jansen; Jordi Martinez-Vilalta edit   pdf
doi  isbn
openurl 
  Title Structure-Preserving Smoothing of Biomedical Images Type Conference Article
  Year 2009 Publication 13th International Conference on Computer Analysis of Images and Patterns Abbreviated Journal  
  Volume 5702 Issue Pages 427-434  
  Keywords non-linear smoothing; differential geometry; anatomical structures segmentation; cardiac magnetic resonance; computerized tomography.  
  Abstract Smoothing of biomedical images should preserve gray-level transitions between adjacent tissues, while restoring contours consistent with anatomical structures. Anisotropic diffusion operators are based on image appearance discontinuities (either local or contextual) and might fail at weak inter-tissue transitions. Meanwhile, the output of block-wise and morphological operations is prone to present a block structure due to the shape and size of the considered pixel neighborhood. In this contribution, we use differential geometry concepts to define a diffusion operator that restricts to image consistent level-sets. In this manner, the final state is a non-uniform intensity image presenting homogeneous inter-tissue transitions along anatomical structures, while smoothing intra-structure texture. Experiments on different types of medical images (magnetic resonance, computerized tomography) illustrate its benefit on a further process (such as segmentation) of images.  
  Address Münster, Germany  
  Corporate Author Thesis  
  Publisher Springer Berlin Heidelberg Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title LNCS  
  Series Volume Series Issue Edition  
  ISSN 0302-9743 ISBN 978-3-642-03766-5 Medium  
  Area Expedition Conference CAIP  
  Notes (down) IAM Approved no  
  Call Number IAM @ iam @ GHB2009 Serial 1527  
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Author Aura Hernandez-Sabate; Debora Gil; Albert Teis edit   pdf
doi  openurl
  Title How Do Conservation Laws Define a Motion Suppression Score in In-Vivo Ivus Sequences? Type Conference Article
  Year 2007 Publication Proc. IEEE Ultrasonics Symp Abbreviated Journal  
  Volume Issue Pages 2231-2234  
  Keywords validation standards; IVUS motion compensation; conservation laws.  
  Abstract Evaluation of arterial tissue biomechanics for diagnosis and treatment of cardiovascular diseases is an active research field in the biomedical imaging processing area. IntraVascular UltraSound (IVUS) is a unique tool for such assessment since it reflects tissue morphology and deformation. A proper quantification and visualization of both properties is hindered by vessel structures misalignments introduced by cardiac dynamics. This has encouraged development of IVUS motion compensation techniques. However, there is a lack of an objective evaluation of motion reduction ensuring a reliable clinical application This work reports a novel score, the Conservation of Density Rate (CDR), for validation of motion compensation in in-vivo pullbacks. Synthetic experiments validate the proposed score as measure of motion parameters accuracy; while results in in vivo pullbacks show its reliability in clinical cases.  
  Address  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference  
  Notes (down) IAM Approved no  
  Call Number IAM @ iam @ HTG2007 Serial 1550  
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Author Enric Marti; Jordi Regincos; Jaime Lopez-Krahe edit  openurl
  Title Interpretación de Dibujos Lineales a Mano Alzada Representando Escenas Tridimensionales Type Conference Article
  Year 1991 Publication Primer Congreso Español de Informática. Abbreviated Journal  
  Volume Issue Pages  
  Keywords  
  Abstract  
  Address  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference  
  Notes (down) IAM Approved no  
  Call Number IAM @ iam @ MRL1991 Serial 1610  
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Author Ferran Poveda; Jaume Garcia; Enric Marti; Debora Gil edit   pdf
openurl 
  Title Validation of the myocardial architecture in DT-MRI tractography Type Conference Article
  Year 2010 Publication Medical Image Computing in Catalunya: Graduate Student Workshop Abbreviated Journal  
  Volume Issue Pages 29-30  
  Keywords  
  Abstract Deep understanding of myocardial structure may help to link form and funcion of the heart unraveling crucial knowledge for medical and surgical clinical procedures and studies. In this work we introduce two visualization techniques based on DT-MRI streamlining able to decipher interesting properties of the architectural organization of the heart.  
  Address  
  Corporate Author Thesis  
  Publisher Place of Publication Girona (Spain) Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference MICCAT  
  Notes (down) IAM Approved no  
  Call Number IAM @ iam @ PGM2010 Serial 1626  
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Author Oriol Rodriguez-Leon; Debora Gil; Eduard Fernandez-Nofrerias; H.Tizon; S.Montserrat; Vicente del Valle;Josefina Mauri edit  openurl
  Title Caracterització de la Perfusió Miocàrdica mitjançant anàlisi estadístic de l espectre en l angiografia de contrast Type Conference Article
  Year 2007 Publication XIX Congrés de la Societat Catalana de Cardiologia de Barcelona Abbreviated Journal  
  Volume Issue Pages 130  
  Keywords  
  Abstract La valoració de la integritat de la microcirculació coronària aporta informació pronòstica en pacients amb infart agut de miocardi en els que es realitza angioplastia primària. Aquesta valoració és subjectiva i presenta una important variabilitat si no es duta a terme per personal experimentat. Presentem una eina d’anàlisi d’imatge que permet fer una valoració de la microcirculació coronària a partir de seqüències d’angiografia. Hem analitzat les variacions locals en el nivell de gris de la imatge durant la seqüència angiogràfica. Hem identificat els principals fenòmens observats (respiració, batec cardíac, tinció arterial, tinció miocàrdica i soroll radiològic) mitjançant un anàlisi estadístic de l’espectre de Fourier de l’evolució al llarg del temps de la mitja local. Aquest mateix anàlisis permet determinat la influència de cadascun d’ells en la extracció del patró de tinció i selecciona la respiració com el fenomen que més distorsiona el patró de tinció original. Els descriptors proposats s’obtenen fora del rang espectral respiratori. Hem testat la seva capacitat per a detectar els tres fenòmens principals (tinció miocàrdica (MS), tinció arterial (AS) i soroll (NS)) independentment de la respiració. La capacitat de discriminació dels descriptors ha estat valorada mitjançant un mètode de crossvalidation en 30 seqüències d’angiografia. Els descriptors emprats permeten caracteritzar la tinció miocàrdica amb una alta eficiència i fiabilitat. A més no hi ha diferències significatives en l’anàlisi de les seqüències obtingudes amb el pacient respirant amb normalitat o en apnea  
  Address  
  Corporate Author Thesis  
  Publisher Place of Publication Barcelona (Spain) Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference  
  Notes (down) IAM Approved no  
  Call Number IAM @ iam @ RGF2007 Serial 1639  
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Author David Roche; Debora Gil; Jesus Giraldo edit   pdf
url  isbn
openurl 
  Title An inference model for analyzing termination conditions of Evolutionary Algorithms Type Conference Article
  Year 2011 Publication 14th Congrès Català en Intel·ligencia Artificial Abbreviated Journal  
  Volume Issue Pages 216-225  
  Keywords Evolutionary Computation Convergence, Termination Conditions, Statistical Inference  
  Abstract In real-world problems, it is mandatory to design a termination condition for Evolutionary Algorithms (EAs) ensuring stabilization close to the unknown optimum. Distribution-based quantities are good candidates as far as suitable parameters are used. A main limitation for application to real-world problems is that such parameters strongly depend on the topology of the objective function, as well as, the EA paradigm used.
We claim that the termination problem would be fully solved if we had a model measuring to what extent a distribution-based quantity asymptotically behaves like the solution accuracy. We present a regression-prediction model that relates any two given quantities and reports if they can be statistically swapped as termination conditions. Our framework is applied to two issues. First, exploring if the parameters involved in the computation of distribution-based quantities influence their asymptotic behavior. Second, to what extent existing distribution-based quantities can be asymptotically exchanged for the accuracy of the EA solution.
 
  Address Lleida, Catalonia (Spain)  
  Corporate Author Associació Catalana Intel·ligència Artificial Thesis  
  Publisher Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN 978-1-60750-841-0 Medium  
  Area Expedition Conference CCIA  
  Notes (down) IAM Approved no  
  Call Number IAM @ iam @ RGG2011a Serial 1677  
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Author Ferran Poveda; Debora Gil ;Albert Andaluz ;Enric Marti edit   pdf
url  doi
openurl 
  Title Multiscale Tractography for Representing Heart Muscular Architecture Type Conference Article
  Year 2011 Publication In MICCAI 2011 Workshop on Computational Diffusion MRI Abbreviated Journal  
  Volume Issue Pages  
  Keywords  
  Abstract Deep understanding of myocardial structure of the heart would unravel crucial knowledge for clinical and medical procedures. Although the muscular architecture of the heart has been debated by countless researchers, the controversy is still alive. Diffusion Tensor MRI, DT-MRI, is a unique imaging technique for computational validation of the muscular structure of the heart. By the complex arrangement of myocites, existing techniques can not provide comprehensive descriptions of the global muscular architecture. In this paper we introduce a multiresolution reconstruction technique based on DT-MRI streamlining for simplified global myocardial model generation. Our reconstructions can restore the most complex myocardial structures and indicate a global helical organization  
  Address  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language english Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference CDRMI  
  Notes (down) IAM Approved no  
  Call Number IAM @ iam @ PGA2011 Serial 1681  
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