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Author Ferran Poveda; Debora Gil ;Albert Andaluz ;Enric Marti edit   pdf
url  doi
openurl 
  Title Multiscale Tractography for Representing Heart Muscular Architecture Type Conference Article
  Year 2011 Publication In MICCAI 2011 Workshop on Computational Diffusion MRI Abbreviated Journal  
  Volume Issue Pages  
  Keywords  
  Abstract Deep understanding of myocardial structure of the heart would unravel crucial knowledge for clinical and medical procedures. Although the muscular architecture of the heart has been debated by countless researchers, the controversy is still alive. Diffusion Tensor MRI, DT-MRI, is a unique imaging technique for computational validation of the muscular structure of the heart. By the complex arrangement of myocites, existing techniques can not provide comprehensive descriptions of the global muscular architecture. In this paper we introduce a multiresolution reconstruction technique based on DT-MRI streamlining for simplified global myocardial model generation. Our reconstructions can restore the most complex myocardial structures and indicate a global helical organization  
  Address  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language (down) English Summary Language english Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference CDRMI  
  Notes IAM Approved no  
  Call Number IAM @ iam @ PGA2011 Serial 1681  
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Author Patricia Marquez; Debora Gil; Aura Hernandez-Sabate edit   pdf
url  doi
openurl 
  Title A Confidence Measure for Assessing Optical Flow Accuracy in the Absence of Ground Truth Type Conference Article
  Year 2011 Publication IEEE International Conference on Computer Vision – Workshops Abbreviated Journal  
  Volume Issue Pages 2042-2049  
  Keywords IEEE International Conference on Computer Vision – Workshops  
  Abstract Optical flow is a valuable tool for motion analysis in autonomous navigation systems. A reliable application requires determining the accuracy of the computed optical flow. This is a main challenge given the absence of ground truth in real world sequences. This paper introduces a measure of optical flow accuracy for Lucas-Kanade based flows in terms of the numerical stability of the data-term. We call this measure optical flow condition number. A statistical analysis over ground-truth data show a good statistical correlation between the condition number and optical flow error. Experiments on driving sequences illustrate its potential for autonomous navigation systems.  
  Address  
  Corporate Author Thesis  
  Publisher IEEE Place of Publication Barcelona (Spain) Editor  
  Language (down) English Summary Language English Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference ICCVW  
  Notes IAM; ADAS Approved no  
  Call Number IAM @ iam @ MGH2011 Serial 1682  
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Author Debora Gil; Agnes Borras; Manuel Ballester; Francesc Carreras; Ruth Aris; Manuel Vazquez; Enric Marti; Ferran Poveda edit   pdf
url  doi
isbn  openurl
  Title MIOCARDIA: Integrating cardiac function and muscular architecture for a better diagnosis Type Conference Article
  Year 2011 Publication 14th International Symposium on Applied Sciences in Biomedical and Communication Technologies Abbreviated Journal  
  Volume Issue Pages  
  Keywords  
  Abstract Deep understanding of myocardial structure of the heart would unravel crucial knowledge for clinical and medical procedures. The MIOCARDIA project is a multidisciplinary project in cooperation with l'Hospital de la Santa Creu i de Sant Pau, Clinica la Creu Blanca and Barcelona Supercomputing Center. The ultimate goal of this project is defining a computational model of the myocardium. The model takes into account the deep interrelation between the anatomy and the mechanics of the heart. The paper explains the workflow of the MIOCARDIA project. It also introduces a multiresolution reconstruction technique based on DT-MRI streamlining for simplified global myocardial model generation. Our reconstructions can restore the most complex myocardial structures and provides evidences of a global helical organization.  
  Address Barcelona; Spain  
  Corporate Author Association for Computing Machinery Thesis  
  Publisher Place of Publication Barcelona, Spain Editor Association for Computing Machinery  
  Language (down) english Summary Language english Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN 978-1-4503-0913-4 Medium  
  Area Expedition Conference ISABEL  
  Notes IAM Approved no  
  Call Number IAM @ iam @ GGB2011 Serial 1691  
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Author David Roche; Debora Gil; Jesus Giraldo edit   pdf
url  openurl
  Title Assessing agonist efficacy in an uncertain Em world Type Conference Article
  Year 2012 Publication 40th Keystone Symposia on mollecular and celular biology Abbreviated Journal  
  Volume Issue Pages 79  
  Keywords  
  Abstract The operational model of agonism has been widely used for the analysis of agonist action since its formulation in 1983. The model includes the Em parameter, which is defined as the maximum response of the system. The methods for Em estimation provide Em values not significantly higher than the maximum responses achieved by full agonists. However, it has been found that that some classes of compounds as, for instance, superagonists and positive allosteric modulators can increase the full agonist maximum response, implying upper limits for Em and thereby posing doubts on the validity of Em estimates. Because of the correlation between Em and operational efficacy, τ, wrong Em estimates will yield wrong τ estimates.
In this presentation, the operational model of agonism and various methods for the simulation of allosteric modulation will be analyzed. Alternatives for curve fitting will be presented and discussed.
 
  Address Fairmont Banff Springs, Banff, Alberta, Canada  
  Corporate Author Keystone Symposia Thesis  
  Publisher Keystone Symposia Place of Publication Editor A. Christopoulus and M. Bouvier  
  Language (down) english Summary Language english Original Title  
  Series Editor Keystone Symposia Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference KSMCB  
  Notes IAM Approved no  
  Call Number IAM @ iam @ RGG2012 Serial 1855  
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Author Patricia Marquez; Debora Gil ; Aura Hernandez-Sabate edit   pdf
doi  isbn
openurl 
  Title Error Analysis for Lucas-Kanade Based Schemes Type Conference Article
  Year 2012 Publication 9th International Conference on Image Analysis and Recognition Abbreviated Journal  
  Volume 7324 Issue I Pages 184-191  
  Keywords Optical flow, Confidence measure, Lucas-Kanade, Cardiac Magnetic Resonance  
  Abstract Optical flow is a valuable tool for motion analysis in medical imaging sequences. A reliable application requires determining the accuracy of the computed optical flow. This is a main challenge given the absence of ground truth in medical sequences. This paper presents an error analysis of Lucas-Kanade schemes in terms of intrinsic design errors and numerical stability of the algorithm. Our analysis provides a confidence measure that is naturally correlated to the accuracy of the flow field. Our experiments show the higher predictive value of our confidence measure compared to existing measures.  
  Address Aveiro, Portugal  
  Corporate Author Thesis  
  Publisher Springer-Verlag Berlin Heidelberg Place of Publication Editor  
  Language (down) english Summary Language Original Title  
  Series Editor Campilho, Aurélio and Kamel, Mohamed Series Title Lecture Notes in Computer Science Abbreviated Series Title LNCS  
  Series Volume Series Issue Edition  
  ISSN 0302-9743 ISBN 978-3-642-31294-6 Medium  
  Area Expedition Conference ICIAR  
  Notes IAM Approved no  
  Call Number IAM @ iam @ MGH2012a Serial 1899  
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Author Jaume Garcia; Debora Gil; Francesc Carreras; Sandra Pujades; R.Leta; Xavier Alomar; Guillem Pons-LLados edit   pdf
url  openurl
  Title Patrons de Normalitat Regional per la Valoració de la Funció del Ventricle Esquerre Type Conference Article
  Year 2008 Publication XX Congrés de la Societat Catalana de Cardiologia Abbreviated Journal  
  Volume Issue Pages 60  
  Keywords  
  Abstract Les malalties cardiovasculars afecten les propietats contràctils de la banda ventricular i provoquen una variació de la funció del Ventricle Esquerre (VE) . Només els indicadors locals (strains, la deformació del teixit) són capaços de detectar anomalies en territoris específics del VE . Patrons de normalitat regionals d’aquests paràmetres serien d’utilitat a l’hora de valorar-ne la funció .
Presentem un Domini Paramètric Normalitzat (DPN) que permet comparar dades de diferents pacients i definir Patrons de Normalitat Regional (PNR)
 
  Address  
  Corporate Author Thesis  
  Publisher Place of Publication Barcelona Editor  
  Language (down) catalan Summary Language catalan Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference  
  Notes IAM; Approved no  
  Call Number IAM @ iam @ GGC2008b Serial 1503  
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Author Jaume Garcia; Debora Gil; Francesc Carreras ; Sandra Pujades; R.Leta; Xavier Alomar; Guillem Pons-LLados edit   pdf
openurl 
  Title Un Model 3D del Ventricle Esquerre Integrant Anatomia i Funcionalitat Type Conference Article
  Year 2008 Publication XX Congrés de la Societat Catalana de Cardiologia, Actes del Congres Abbreviated Journal  
  Volume Issue Pages 122  
  Keywords  
  Abstract Els canvis en la dinàmica del Ventricle Esquerre (VE) reflecteixen la majoria de malalties cardiovasculars . Els avenços en imatge mèdica han impulsat la recerca en models i simulacions de la dinàmica 3D del VE . La majoria dels models existents sols consideren l’anatomia externa del VE i no permeten una avaluació de l’acoblament electromecànic . Donat que la mecànica d’un muscle depèn de la orientació de les seves fibres, un model realista hauria d’incloure la disposició espacial de la banda ventricular helicoidal (BVH) .
Proposem desenvolupar un model del VE adaptat a cada pacient que integri, per primer cop, l’anatomia de la banda ventricular, l’anatomia externa del VE i la seva funcionalitat, per a una millor determinació del patró d’activació electromecànica
 
  Address  
  Corporate Author Thesis  
  Publisher Place of Publication Barcelona Editor  
  Language (down) catalan Summary Language catalan Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference  
  Notes IAM Approved no  
  Call Number IAM @ iam @ GGC2008c Serial 1504  
Permanent link to this record
 

 
Author Joel Barajas; Jaume Garcia; Francesc Carreras; Sandra Pujades; Petia Radeva edit   pdf
url  isbn
openurl 
  Title Angle Images Using Gabor Filters in Cardiac Tagged MRI Type Conference Article
  Year 2005 Publication Proceeding of the 2005 conference on Artificial Intelligence Research and Development Abbreviated Journal  
  Volume Issue Pages 107-114  
  Keywords Angle Images, Gabor Filters, Harp, Tagged Mri  
  Abstract Tagged Magnetic Resonance Imaging (MRI) is a non-invasive technique used to examine cardiac deformation in vivo. An Angle Image is a representation of a Tagged MRI which recovers the relative position of the tissue respect to the distorted tags. Thus cardiac deformation can be estimated. This paper describes a new approach to generate Angle Images using a bank of Gabor filters in short axis cardiac Tagged MRI. Our method improves the Angle Images obtained by global techniques, like HARP, with a local frequency analysis. We propose to use the phase response of a combination of a Gabor filters bank, and use it to find a more precise deformation of the left ventricle. We demonstrate the accuracy of our method over HARP by several experimental results.  
  Address Amsterdam; The Netherlands  
  Corporate Author Thesis  
  Publisher IOS Press Place of Publication Amsterdam, The Netherlands Editor  
  Language (down) Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN 1-58603-560-6 Medium  
  Area Expedition Conference CAIRD  
  Notes IAM;MILAB Approved no  
  Call Number BCNPCL @ bcnpcl @ BGC2005; IAM @ iam Serial 595  
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Author Jaume Garcia; Joel Barajas; Francesc Carreras; Sandra Pujades; Petia Radeva edit   pdf
doi  isbn
openurl 
  Title An intuitive validation technique to compare local versus global tagged MRI analysis Type Conference Article
  Year 2005 Publication Computers In Cardiology Abbreviated Journal  
  Volume 32 Issue Pages 29–32  
  Keywords  
  Abstract Myocardium appears as a uniform tissue that seen in convectional Magnetic Resonance Images (MRI) shows just the contractile part of its movement. MR Tagging is a unique imaging technique that prints a grid over the tissue which moves according to the underlying movement of the myocardium revealing the true deformation of the cardiac muscle. Optical flow techniques based on spectral information estimate tissue displacement by analyzing information encoded in the phase maps which can be obtained using, local (Gabor) and global (HARP) methods. In this paper we compare both in synthetic and real Tagged MR sequences. We conclude that local method is slightly more accurate than the global one. On the other hand, global method is more efficient as it is much faster and less parameters have to be taken into account  
  Address Lyon (France)  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language (down) Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN 0-7803-9337-6 Medium  
  Area Expedition Conference  
  Notes IAM;MILAB Approved no  
  Call Number IAM @ iam @ GBC2005 Serial 639  
Permanent link to this record
 

 
Author Debora Gil; Jaume Garcia; Mariano Vazquez; Ruth Aris; Guilleaume Houzeaux edit   pdf
isbn  openurl
  Title Patient-Sensitive Anatomic and Functional 3D Model of the Left Ventricle Function Type Conference Article
  Year 2008 Publication 8th World Congress on Computational Mechanichs (WCCM8) Abbreviated Journal  
  Volume Issue Pages  
  Keywords Left Ventricle, Electromechanical Models, Image Processing, Magnetic Resonance.  
  Abstract Early diagnosis and accurate treatment of Left Ventricle (LV) dysfunction significantly increases the patient survival. Impairment of LV contractility due to cardiovascular diseases is reflected in its motion patterns. Recent advances in medical imaging, such as Magnetic Resonance (MR), have encouraged research on 3D simulation and modelling of the LV dynamics. Most of the existing 3D models [1] consider just the gross anatomy of the LV and restore a truncated ellipse which deforms along the cardiac cycle. The contraction mechanics of any muscle strongly depends on the spatial orientation of its muscular fibers since the motion that the muscle undergoes mainly takes place along the fibers. It follows that such simplified models do not allow evaluation of the heart electro-mechanical function and coupling, which has recently risen as the key point for understanding the LV functionality [2]. In order to thoroughly understand the LV mechanics it is necessary to consider the complete anatomy of the LV given by the orientation of the myocardial fibres in 3D space as described by Torrent Guasp [3].
We propose developing a 3D patient-sensitive model of the LV integrating, for the first time, the ven- tricular band anatomy (fibers orientation), the LV gross anatomy and its functionality. Such model will represent the LV function as a natural consequence of its own ventricular band anatomy. This might be decisive in restoring a proper LV contraction in patients undergoing pace marker treatment.
The LV function is defined as soon as the propagation of the contractile electromechanical pulse has been modelled. In our experiments we have used the wave equation for the propagation of the electric pulse. The electromechanical wave moves on the myocardial surface and should have a conductivity tensor oriented along the muscular fibers. Thus, whatever mathematical model for electric pulse propa- gation [4] we consider, the complete anatomy of the LV should be extracted.
The LV gross anatomy is obtained by processing multi slice MR images recorded for each patient. Information about the myocardial fibers distribution can only be extracted by Diffusion Tensor Imag- ing (DTI), which can not provide in vivo information for each patient. As a first approach, we have
Figure 1: Scheme for the Left Ventricle Patient-Sensitive Model.
computed an average model of fibers from several DTI studies of canine hearts. This rough anatomy is the input for our electro-mechanical propagation model simulating LV dynamics. The average fiber orientation is updated until the simulated LV motion agrees with the experimental evidence provided by the LV motion observed in tagged MR (TMR) sequences. Experimental LV motion is recovered by applying image processing, differential geometry and interpolation techniques to 2D TMR slices [5]. The pipeline in figure 1 outlines the interaction between simulations and experimental data leading to our patient-tailored model.
 
  Address Venice; Italy  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language (down) Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN 9788496736559 Medium  
  Area Expedition Conference  
  Notes IAM; Approved no  
  Call Number IAM @ iam @ GGV2008b Serial 993  
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