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Author H. Martin ; Jens Fagertun; Sergio Vera; Debora Gil edit   pdf
openurl 
  Title Medial structure generation for registration of anatomical structures Type Book Chapter
  Year (down) 2017 Publication Skeletonization, Theory, Methods and Applications Abbreviated Journal  
  Volume 11 Issue Pages  
  Keywords  
  Abstract  
  Address  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference  
  Notes IAM; 600.096; 600.075; 600.145 Approved no  
  Call Number Admin @ si @ MFV2017a Serial 2935  
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Author David Roche edit  openurl
  Title A Statistical Framework for Terminating Evolutionary Algorithms at their Steady State Type Book Whole
  Year (down) 2015 Publication PhD Thesis, Universitat Autonoma de Barcelona-CVC Abbreviated Journal  
  Volume Issue Pages  
  Keywords  
  Abstract As any iterative technique, it is a necessary condition a stop criterion for terminating Evolutionary Algorithms (EA). In the case of optimization methods, the algorithm should stop at the time it has reached a steady state so it can not improve results anymore. Assessing the reliability of termination conditions for EAs is of prime importance. A wrong or weak stop criterion can negatively a ect both the computational e ort and the nal result.
In this Thesis, we introduce a statistical framework for assessing whether a termination condition is able to stop EA at its steady state. In one hand a numeric approximation to steady states to detect the point in which EA population has lost its diversity has been presented for EA termination. This approximation has been applied to di erent EA paradigms based on diversity and a selection of functions covering the properties most relevant for EA convergence. Experiments show that our condition works regardless of the search space dimension and function landscape and Di erential Evolution (DE) arises as the best paradigm. On the other hand, we use a regression model in order to determine the requirements ensuring that a measure derived from EA evolving population is related to the distance to the optimum in xspace.
Our theoretical framework is analyzed across several benchmark test functions
and two standard termination criteria based on function improvement in f-space and EA population x-space distribution for the DE paradigm. Results validate our statistical framework as a powerful tool for determining the capability of a measure for terminating EA and select the x-space distribution as the best-suited for accurately stopping DE in real-world applications.
 
  Address July 2015  
  Corporate Author Thesis Ph.D. thesis  
  Publisher Ediciones Graficas Rey Place of Publication Editor Debora Gil; Jesus Giraldo  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference  
  Notes IAM; 600.075 Approved no  
  Call Number Admin @ si @ Roc2015 Serial 2686  
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Author Debora Gil; F. Javier Sanchez; Gloria Fernandez-Esparrach; Jorge Bernal edit   pdf
doi  openurl
  Title 3D Stable Spatio-temporal Polyp Localization in Colonoscopy Videos Type Book Chapter
  Year (down) 2015 Publication Computer-Assisted and Robotic Endoscopy. Revised selected papers of Second International Workshop, CARE 2015, Held in Conjunction with MICCAI 2015 Abbreviated Journal  
  Volume 9515 Issue Pages 140-152  
  Keywords Colonoscopy, Polyp Detection, Polyp Localization, Region Extraction, Watersheds  
  Abstract Computational intelligent systems could reduce polyp miss rate in colonoscopy for colon cancer diagnosis and, thus, increase the efficiency of the procedure. One of the main problems of existing polyp localization methods is a lack of spatio-temporal stability in their response. We propose to explore the response of a given polyp localization across temporal windows in order to select
those image regions presenting the highest stable spatio-temporal response.
Spatio-temporal stability is achieved by extracting 3D watershed regions on the
temporal window. Stability in localization response is statistically determined by analysis of the variance of the output of the localization method inside each 3D region. We have explored the benefits of considering spatio-temporal stability in two different tasks: polyp localization and polyp detection. Experimental results indicate an average improvement of 21:5% in polyp localization and 43:78% in polyp detection.
 
  Address  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title LNCS  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference CARE  
  Notes IAM; MV; 600.075 Approved no  
  Call Number Admin @ si @ GSF2015 Serial 2733  
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Author Hanne Kause; Aura Hernandez-Sabate; Patricia Marquez; Andrea Fuster; Luc Florack; Hans van Assen; Debora Gil edit   pdf
doi  isbn
openurl 
  Title Confidence Measures for Assessing the HARP Algorithm in Tagged Magnetic Resonance Imaging Type Book Chapter
  Year (down) 2015 Publication Statistical Atlases and Computational Models of the Heart. Revised selected papers of Imaging and Modelling Challenges 6th International Workshop, STACOM 2015, Held in Conjunction with MICCAI 2015 Abbreviated Journal  
  Volume 9534 Issue Pages 69-79  
  Keywords  
  Abstract Cardiac deformation and changes therein have been linked to pathologies. Both can be extracted in detail from tagged Magnetic Resonance Imaging (tMRI) using harmonic phase (HARP) images. Although point tracking algorithms have shown to have high accuracies on HARP images, these vary with position. Detecting and discarding areas with unreliable results is crucial for use in clinical support systems. This paper assesses the capability of two confidence measures (CMs), based on energy and image structure, for detecting locations with reduced accuracy in motion tracking results. These CMs were tested on a database of simulated tMRI images containing the most common artifacts that may affect tracking accuracy. CM performance is assessed based on its capability for HARP tracking error bounding and compared in terms of significant differences detected using a multi comparison analysis of variance that takes into account the most influential factors on HARP tracking performance. Results showed that the CM based on image structure was better suited to detect unreliable optical flow vectors. In addition, it was shown that CMs can be used to detect optical flow vectors with large errors in order to improve the optical flow obtained with the HARP tracking algorithm.  
  Address Munich; Germany; January 2015  
  Corporate Author Thesis  
  Publisher Springer International Publishing Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title LNCS  
  Series Volume Series Issue Edition  
  ISSN 0302-9743 ISBN 978-3-319-28711-9 Medium  
  Area Expedition Conference STACOM  
  Notes ADAS; IAM; 600.075; 600.076; 600.060; 601.145 Approved no  
  Call Number Admin @ si @ KHM2015 Serial 2734  
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Author Patricia Marquez edit  isbn
openurl 
  Title A Confidence Framework for the Assessment of Optical Flow Performance Type Book Whole
  Year (down) 2015 Publication PhD Thesis, Universitat Autonoma de Barcelona-CVC Abbreviated Journal  
  Volume Issue Pages  
  Keywords  
  Abstract Optical Flow (OF) is the input of a wide range of decision support systems such as car driver assistance, UAV guiding or medical diagnose. In these real situations, the absence of ground truth forces to assess OF quality using quantities computed from either sequences or the computed optical flow itself. These quantities are generally known as Confidence Measures, CM. Even if we have a proper confidence measure we still need a way to evaluate its ability to discard pixels with an OF prone to have a large error. Current approaches only provide a descriptive evaluation of the CM performance but such approaches are not capable to fairly compare different confidence measures and optical flow algorithms. Thus, it is of prime importance to define a framework and a general road map for the evaluation of optical flow performance.

This thesis provides a framework able to decide which pairs “ optical flow – confidence measure” (OF-CM) are best suited for optical flow error bounding given a confidence level determined by a decision support system. To design this framework we cover the following points:

Descriptive scores. As a first step, we summarize and analyze the sources of inaccuracies in the output of optical flow algorithms. Second, we present several descriptive plots that visually assess CM capabilities for OF error bounding. In addition to the descriptive plots, given a plot representing OF-CM capabilities to bound the error, we provide a numeric score that categorizes the plot according to its decreasing profile, that is, a score assessing CM performance.
Statistical framework. We provide a comparison framework that assesses the best suited OF-CM pair for error bounding that uses a two stage cascade process. First of all we assess the predictive value of the confidence measures by means of a descriptive plot. Then, for a sample of descriptive plots computed over training frames, we obtain a generic curve that will be used for sequences with no ground truth. As a second step, we evaluate the obtained general curve and its capabilities to really reflect the predictive value of a confidence measure using the variability across train frames by means of ANOVA.

The presented framework has shown its potential in the application on clinical decision support systems. In particular, we have analyzed the impact of the different image artifacts such as noise and decay to the output of optical flow in a cardiac diagnose system and we have improved the navigation inside the bronchial tree on bronchoscopy.
 
  Address July 2015  
  Corporate Author Thesis Ph.D. thesis  
  Publisher Ediciones Graficas Rey Place of Publication Editor Debora Gil; Aura Hernandez  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN 978-84-943427-2-1 Medium  
  Area Expedition Conference  
  Notes IAM; 600.075 Approved no  
  Call Number Admin @ si @ Mar2015 Serial 2687  
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Author Sergio Vera edit  isbn
openurl 
  Title Anatomic Registration based on Medial Axis Parametrizations Type Book Whole
  Year (down) 2015 Publication PhD Thesis, Universitat Autonoma de Barcelona-CVC Abbreviated Journal  
  Volume Issue Pages  
  Keywords  
  Abstract Image registration has been for many years the gold standard method to bring two images into correspondence. It has been used extensively in the eld of medical imaging in order to put images of di erent patients into a common overlapping spatial position. However, medical image registration is a slow, iterative optimization process, where many variables and prone to fall into the pit traps local minima.
A coordinate system parameterizing the interior of organs is a powerful tool for a systematic localization of injured tissue. If the same coordinate values are assigned to speci c anatomical sites, parameterizations ensure integration of data across different medical image modalities. Harmonic mappings have been used to produce parametric meshes over the surface of anatomical shapes, given their ability to set values at speci c locations through boundary conditions. However, most of the existing implementations in medical imaging restrict to either anatomical surfaces, or the depth coordinate with boundary conditions is given at discrete sites of limited geometric diversity.
The medial surface of the shape can be used to provide a continuous basis for the de nition of a depth coordinate. However, given that di erent methods for generation of medial surfaces generate di erent manifolds, not all of them are equally suited to be the basis of radial coordinate for a parameterization. It would be desirable that the medial surface will be smooth, and robust to surface shape noise, with low number of spurious branches or surfaces.
In this thesis we present methods for computation of smooth medial manifolds and apply them to the generation of for anatomical volumetric parameterization that extends current harmonic parameterizations to the interior anatomy using information provided by the volume medial surface. This reference system sets a solid base for creating anatomical models of the anatomical shapes, and allows comparing several patients in a common framework of reference.
 
  Address November 2015  
  Corporate Author Thesis Ph.D. thesis  
  Publisher Ediciones Graficas Rey Place of Publication Editor Debora Gil; Miguel Angel Gonzalez Ballester  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN 978-84-943427-8-3 Medium  
  Area Expedition Conference  
  Notes IAM; 600.075 Approved no  
  Call Number Admin @ si @ Ver2015 Serial 2708  
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Author Carles Sanchez edit  isbn
openurl 
  Title Tracheal Structure Characterization using Geometric and Appearance Models for Efficient Assessment of Stenosis in Videobronchoscopy Type Book Whole
  Year (down) 2014 Publication PhD Thesis, Universitat Autonoma de Barcelona-CVC Abbreviated Journal  
  Volume Issue Pages  
  Keywords  
  Abstract Recent advances in endoscopic devices have increased their use for minimal invasive diagnostic and intervention procedures. Among all endoscopic modalities, bronchoscopy is one of the most frequent with around 261 millions of procedures per year. Although the use of bronchoscopy is spread among clinical facilities it presents some drawbacks, being the visual inspection for the assessment of anatomical measurements the most prevalent of them. In
particular, inaccuracies in the estimation of the degree of stenosis (the percentage of obstructed airway) decreases its diagnostic yield and might lead to erroneous treatments. An objective computation of tracheal stenosis in bronchoscopy videos would constitute a breakthrough for this non-invasive technique and a reduction in treatment cost.
This thesis settles the first steps towards on-line reliable extraction of anatomical information from videobronchoscopy for computation of objective measures. In particular, we focus on the computation of the degree of stenosis, which is obtained by comparing the area delimited by a healthy tracheal ring and the stenosed lumen. Reliable extraction of airway structures in interventional videobronchoscopy is a challenging task. This is mainly due to the large variety of acquisition conditions (positions and illumination), devices (different digitalizations) and in videos acquired at the operating room the unpredicted presence of surgical devices (such as probe ends). This thesis contributes to on-line stenosis assessment in several ways. We
propose a parametric strategy for the extraction of lumen and tracheal rings regions based on the characterization of their geometry and appearance that guide a deformable model. The geometric and appearance characterization is based on a physical model describing the way bronchoscopy images are obtained and includes local and global descriptions. In order to ensure a systematic applicability we present a statistical framework to select the optimal
parameters of our method. Experiments perform on the first public annotated database, show that the performance of our method is comparable to the one provided by clinicians and its computation time allows for a on-line implementation in the operating room.
 
  Address  
  Corporate Author Thesis Ph.D. thesis  
  Publisher Ediciones Graficas Rey Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN 978-84-940902-9-5 Medium  
  Area Expedition Conference  
  Notes IAM; 600.075 Approved no  
  Call Number Admin @ si @ San2014 Serial 2575  
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Author David Roche; Debora Gil; Jesus Giraldo edit  doi
isbn  openurl
  Title Mathematical modeling of G protein-coupled receptor function: What can we learn from empirical and mechanistic models? Type Book Chapter
  Year (down) 2014 Publication G Protein-Coupled Receptors – Modeling and Simulation Advances in Experimental Medicine and Biology Abbreviated Journal  
  Volume 796 Issue 3 Pages 159-181  
  Keywords β-arrestin; biased agonism; curve fitting; empirical modeling; evolutionary algorithm; functional selectivity; G protein; GPCR; Hill coefficient; intrinsic efficacy; inverse agonism; mathematical modeling; mechanistic modeling; operational model; parameter optimization; receptor dimer; receptor oligomerization; receptor constitutive activity; signal transduction; two-state model  
  Abstract Empirical and mechanistic models differ in their approaches to the analysis of pharmacological effect. Whereas the parameters of the former are not physical constants those of the latter embody the nature, often complex, of biology. Empirical models are exclusively used for curve fitting, merely to characterize the shape of the E/[A] curves. Mechanistic models, on the contrary, enable the examination of mechanistic hypotheses by parameter simulation. Regretfully, the many parameters that mechanistic models may include can represent a great difficulty for curve fitting, representing, thus, a challenge for computational method development. In the present study some empirical and mechanistic models are shown and the connections, which may appear in a number of cases between them, are analyzed from the curves they yield. It may be concluded that systematic and careful curve shape analysis can be extremely useful for the understanding of receptor function, ligand classification and drug discovery, thus providing a common language for the communication between pharmacologists and medicinal chemists.  
  Address  
  Corporate Author Thesis  
  Publisher Springer Netherlands Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0065-2598 ISBN 978-94-007-7422-3 Medium  
  Area Expedition Conference  
  Notes IAM; 600.075 Approved no  
  Call Number IAM @ iam @ RGG2014 Serial 2197  
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Author Ferran Poveda edit  openurl
  Title Computer Graphics and Vision Techniques for the Study of the Muscular Fiber Architecture of the Myocardium Type Book Whole
  Year (down) 2013 Publication PhD Thesis, Universitat Autonoma de Barcelona-CVC Abbreviated Journal  
  Volume Issue Pages  
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  Abstract  
  Address  
  Corporate Author Thesis Ph.D. thesis  
  Publisher Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
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  ISSN ISBN Medium  
  Area Expedition Conference  
  Notes IAM Approved no  
  Call Number Admin @ si @ Pov2013 Serial 2417  
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Author Aura Hernandez-Sabate; Debora Gil edit   pdf
url  doi
isbn  openurl
  Title The Benefits of IVUS Dynamics for Retrieving Stable Models of Arteries Type Book Chapter
  Year (down) 2012 Publication Intravascular Ultrasound Abbreviated Journal  
  Volume Issue Pages 185-206  
  Keywords  
  Abstract  
  Address  
  Corporate Author Thesis  
  Publisher Intech Place of Publication Editor Yasuhiro Honda  
  Language English Summary Language english Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN 978-953-307-900-4 Medium  
  Area Expedition Conference  
  Notes IAM; ADAS Approved no  
  Call Number IAM @ iam @ HeG2012 Serial 1684  
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