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H. Martin Kjer; Jens Fagertun; Sergio Vera; Debora Gil |
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Medial structure generation for registration of anatomical structures |
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2017 |
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Skeletonization, Theory, Methods and Applications |
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IAM; 600.096; 600.075; 600.145 |
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Admin @ si @ MFV2017a |
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2935 |
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Mireia Sole; Joan Blanco; Debora Gil; Oliver Valero; G. Fonseka; M. Lawrie; Francesca Vidal; Zaida Sarrate |
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Title |
Chromosome Territories in Mice Spermatogenesis: A new three-dimensional methodology of study |
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Conference Article |
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2017 |
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11th European CytoGenesis Conference |
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Florencia; Italia; July 2017 |
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ECA |
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IAM; 600.096; 600.145 |
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Admin @ si @ SBG2017a |
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2936 |
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Author |
Carles Sanchez; Debora Gil; T. Gache; N. Koufos; Marta Diez-Ferrer; Antoni Rosell |
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Title |
SENSA: a System for Endoscopic Stenosis Assessment |
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2016 |
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28th Conference of the international Society for Medical Innovation and Technology |
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Documenting the severity of a static or dynamic Central Airway Obstruction (CAO) is crucial to establish proper diagnosis and treatment, predict possible treatment effects and better follow-up the patients. The subjective visual evaluation of a stenosis during video-bronchoscopy still remains the most common way to assess a CAO in spite of a consensus among experts for a need to standardize all calculations [1].
The Computer Vision Center in cooperation with the «Hospital de Bellvitge», has developed a System for Endoscopic Stenosis Assessment (SENSA), which computes CAO directly by analyzing standard bronchoscopic data without the need of using other imaging tecnologies. |
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Rotterdam; The Netherlands; October 2016 |
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SMIT |
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IAM; |
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Admin @ si @ SGG2016 |
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2942 |
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Carles Sanchez; Antonio Esteban Lansaque; Agnes Borras; Marta Diez-Ferrer; Antoni Rosell; Debora Gil |
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Towards a Videobronchoscopy Localization System from Airway Centre Tracking |
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2017 |
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12th International Conference on Computer Vision Theory and Applications |
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352-359 |
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Video-bronchoscopy; Lung cancer diagnosis; Airway lumen detection; Region tracking; Guided bronchoscopy navigation |
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Bronchoscopists use fluoroscopy to guide flexible bronchoscopy to the lesion to be biopsied without any kind of incision. Being fluoroscopy an imaging technique based on X-rays, the risk of developmental problems and cancer is increased in those subjects exposed to its application, so minimizing radiation is crucial. Alternative guiding systems such as electromagnetic navigation require specific equipment, increase the cost of the clinical procedure and still require fluoroscopy. In this paper we propose an image based guiding system based on the extraction of airway centres from intra-operative videos. Such anatomical landmarks are matched to the airway centreline extracted from a pre-planned CT to indicate the best path to the nodule. We present a
feasibility study of our navigation system using simulated bronchoscopic videos and a multi-expert validation of landmarks extraction in 3 intra-operative ultrathin explorations. |
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Porto; Portugal; February 2017 |
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VISAPP |
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IAM; 600.096; 600.075; 600.145 |
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Admin @ si @ SEB2017 |
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2943 |
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Marta Diez-Ferrer; Debora Gil; Elena Carreño; Susana Padrones; Samantha Aso; Vanesa Vicens; Noelia Cubero de Frutos; Rosa Lopez Lisbona; Carles Sanchez; Agnes Borras; Antoni Rosell |
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Title |
Positive Airway Pressure-Enhanced CT to Improve Virtual Bronchoscopic Navigation |
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2017 |
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European Respiratory Journal |
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ERJ |
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Admin @ si @ DGC2017b |
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3632 |
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Author |
Debora Gil; Oriol Ramos Terrades; Elisa Minchole; Carles Sanchez; Noelia Cubero de Frutos; Marta Diez-Ferrer; Rosa Maria Ortiz; Antoni Rosell |
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Title |
Classification of Confocal Endomicroscopy Patterns for Diagnosis of Lung Cancer |
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Conference Article |
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2017 |
Publication |
6th Workshop on Clinical Image-based Procedures: Translational Research in Medical Imaging |
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10550 |
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151-159 |
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Confocal Laser Endomicroscopy (CLE) is an emerging imaging technique that allows the in-vivo acquisition of cell patterns of potentially malignant lesions. Such patterns could discriminate between inflammatory and neoplastic lesions and, thus, serve as a first in-vivo biopsy to discard cases that do not actually require a cell biopsy.
The goal of this work is to explore whether CLE images obtained during videobronchoscopy contain enough visual information to discriminate between benign and malign peripheral lesions for lung cancer diagnosis. To do so, we have performed a pilot comparative study with 12 patients (6 adenocarcinoma and 6 benign-inflammatory) using 2 different methods for CLE pattern analysis: visual analysis by 3 experts and a novel methodology that uses graph methods to find patterns in pre-trained feature spaces. Our preliminary results indicate that although visual analysis can only achieve a 60.2% of accuracy, the accuracy of the proposed unsupervised image pattern classification raises to 84.6%.
We conclude that CLE images visual information allow in-vivo detection of neoplastic lesions and graph structural analysis applied to deep-learning feature spaces can achieve competitive results. |
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Quebec; Canada; September 2017 |
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CLIP |
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IAM; 600.096; 600.075; 600.145;DAG |
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Admin @ si @ GRM2017 |
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2957 |
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Author |
Mireia Sole; Joan Blanco; Debora Gil; G. Fonseka; Richard Frodsham; Oliver Valero; Francesca Vidal; Zaida Sarrate |
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Title |
Is there a pattern of Chromosome territoriality along mice spermatogenesis? |
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Conference Article |
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2017 |
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3rd Spanish MeioNet Meeting Abstract Book |
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55-56 |
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Miraflores de la Sierra; Madrid; June 2017 |
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MEIONET |
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IAM; 600.096; 600.145 |
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Admin @ si @ |
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2958 |
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Mireia Sole; Joan Blanco; Debora Gil; G. Fonseka; Richard Frodsham; Oliver Valero; Francesca Vidal; Zaida Sarrate |
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Title |
Unraveling the enigmas of chromosome territoriality during spermatogenesis |
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Conference Article |
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2017 |
Publication |
IX Jornada del Departament de Biologia Cel•lular, Fisiologia i Immunologia |
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UAB; Barcelona; June 2017 |
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IAM; 600.145 |
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Admin @ si @ SBG2017b |
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2959 |
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Mireia Sole; Joan Blanco; Debora Gil; G. Fonseka; Richard Frodsham; Francesca Vidal; Zaida Sarrate |
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Title |
Noves perspectives en l estudi de la territorialitat cromosomica de cel·lules germinals masculines: estudis tridimensionals |
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2017 |
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Biologia de la Reproduccio |
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JBR |
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15 |
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73-78 |
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Abstract |
In somatic cells, chromosomes occupy specific nuclear regions called chromosome territories which are involved in the
maintenance and regulation of the genome. Preliminary data in male germ cells also suggest the importance of chromosome
territoriality in cell functionality. Nevertheless, the specific characteristics of testicular tissue (presence of different
cell types with different morphological characteristics, in different stages of development and with different ploidy)
makes difficult to achieve conclusive results. In this study we have developed a methodology to approach the threedimensional
study of all chromosome territories in male germ cells from C57BL/6J mice (Mus musculus). The method
includes the following steps: i) Optimized cell fixation to obtain an optimal preservation of the three-dimensionality cell
morphology, ii) Chromosome identification by FISH (Chromoprobe Multiprobe® OctoChrome™ Murine System; Cytocell)
and confocal microscopy (TCS-SP5, Leica Microsystems), iii) Cell type identification by immunofluorescence
iv) Image analysis using Matlab scripts, v) Numerical data extraction related to chromosome features, chromosome
radial position and chromosome relative position. This methodology allows the unequivocally identification and the
analysis of the chromosome territories of all spermatogenic stages. Results will provide information about the features
that determine chromosomal position, preferred associations between chromosomes, and the relationship between chromosome
positioning and genome regulation. |
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978-84-697-3767-5 |
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IAM; 600.096; 600.145 |
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Admin @ si @ SBG2017c |
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2961 |
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Pau Cano; Alvaro Caravaca; Debora Gil; Eva Musulen |
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Title |
Diagnosis of Helicobacter pylori using AutoEncoders for the Detection of Anomalous Staining Patterns in Immunohistochemistry Images |
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Miscellaneous |
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2023 |
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Arxiv |
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107241 |
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This work addresses the detection of Helicobacter pylori a bacterium classified since 1994 as class 1 carcinogen to humans. By its highest specificity and sensitivity, the preferred diagnosis technique is the analysis of histological images with immunohistochemical staining, a process in which certain stained antibodies bind to antigens of the biological element of interest. This analysis is a time demanding task, which is currently done by an expert pathologist that visually inspects the digitized samples.
We propose to use autoencoders to learn latent patterns of healthy tissue and detect H. pylori as an anomaly in image staining. Unlike existing classification approaches, an autoencoder is able to learn patterns in an unsupervised manner (without the need of image annotations) with high performance. In particular, our model has an overall 91% of accuracy with 86\% sensitivity, 96% specificity and 0.97 AUC in the detection of H. pylori. |
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IAM |
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Admin @ si @ CCG2023 |
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3855 |
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