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Oriol Rodriguez-Leor; Debora Gil; Eduard Fernandez-Nofrerias; H. Tizon; S. Montserrat; Vicente del Valle; J. Mauri |
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Caracterització de la Perfusió Miocàrdica mitjançant anàlisi estadístic de l espectre en l angiografia de contrast |
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Conference Article |
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2007 |
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XIX Congrés de la Societat Catalana de Cardiologia de Barcelona |
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130 |
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La valoració de la integritat de la microcirculació coronària aporta informació pronòstica en pacients amb infart agut de miocardi en els que es realitza angioplastia primària. Aquesta valoració és subjectiva i presenta una important variabilitat si no es duta a terme per personal experimentat. Presentem una eina d’anàlisi d’imatge que permet fer una valoració de la microcirculació coronària a partir de seqüències d’angiografia. Hem analitzat les variacions locals en el nivell de gris de la imatge durant la seqüència angiogràfica. Hem identificat els principals fenòmens observats (respiració, batec cardíac, tinció arterial, tinció miocàrdica i soroll radiològic) mitjançant un anàlisi estadístic de l’espectre de Fourier de l’evolució al llarg del temps de la mitja local. Aquest mateix anàlisis permet determinat la influència de cadascun d’ells en la extracció del patró de tinció i selecciona la respiració com el fenomen que més distorsiona el patró de tinció original. Els descriptors proposats s’obtenen fora del rang espectral respiratori. Hem testat la seva capacitat per a detectar els tres fenòmens principals (tinció miocàrdica (MS), tinció arterial (AS) i soroll (NS)) independentment de la respiració. La capacitat de discriminació dels descriptors ha estat valorada mitjançant un mètode de crossvalidation en 30 seqüències d’angiografia. Els descriptors emprats permeten caracteritzar la tinció miocàrdica amb una alta eficiència i fiabilitat. A més no hi ha diferències significatives en l’anàlisi de les seqüències obtingudes amb el pacient respirant amb normalitat o en apnea |
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Barcelona (Spain) |
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IAM @ iam @ RGF2007 |
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1639 |
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Author |
Oriol Rodriguez-Leor; Debora Gil; Eduard Fernandez-Nofrerias |
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Analisis en los cambios en el nivel de gris en las secuencias angiograficas mediante descriptores estadisticos para determinar la perfusion miocardica |
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2006 |
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Revista Española de Cardiología |
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REC |
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59 Supl 2-166 |
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2 |
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128 |
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IAM; |
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IAM @ iam @ RGF2006 |
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1640 |
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Jaume Garcia; Debora Gil; Aura Hernandez-Sabate |
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Endowing Canonical Geometries to Cardiac Structures |
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2010 |
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Statistical Atlases And Computational Models Of The Heart |
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6364 |
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124-133 |
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International conference on Cardiac electrophysiological simulation challenge
In this paper, we show that canonical (shape-based) geometries can be endowed to cardiac structures using tubular coordinates defined over their medial axis. We give an analytic formulation of these geometries by means of B-Splines. Since B-Splines present vector space structure PCA can be applied to their control points and statistical models relating boundaries and the interior of the anatomical structures can be derived. We demonstrate the applicability in two cardiac structures, the 3D Left Ventricular volume, and the 2D Left-Right ventricle set in 2D Short Axis view. |
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Springer Berlin / Heidelberg |
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Camara, O.; Pop, M.; Rhode, K.; Sermesant, M.; Smith, N.; Young, A. |
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Lecture Notes in Computer Science |
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LNCS |
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IAM @ iam @ GGH2010b |
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1515 |
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Patricia Marquez;Debora Gil;Aura Hernandez-Sabate |
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Title |
A Complete Confidence Framework for Optical Flow |
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2012 |
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12th European Conference on Computer Vision – Workshops and Demonstrations |
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7584 |
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2 |
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124-133 |
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Optical flow, confidence measures, sparsification plots, error prediction plots |
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Medial representations are powerful tools for describing and parameterizing the volumetric shape of anatomical structures. Existing methods show excellent results when applied to 2D objects, but their quality drops across dimensions. This paper contributes to the computation of medial manifolds in two aspects. First, we provide a standard scheme for the computation of medial manifolds that avoid degenerated medial axis segments; second, we introduce an energy based method which performs independently of the dimension. We evaluate quantitatively the performance of our method with respect to existing approaches, by applying them to synthetic shapes of known medial geometry. Finally, we show results on shape representation of multiple abdominal organs, exploring the use of medial manifolds for the representation of multi-organ relations. |
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Springer-Verlag |
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Florence, Italy, October 7-13, 2012 |
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Andrea Fusiello, Vittorio Murino ,Rita Cucchiara |
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LNCS |
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978-3-642-33867-0 |
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ECCVW |
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IAM;ADAS; |
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IAM @ iam @ MGH2012b |
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1991 |
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Jaume Garcia; Debora Gil; Francesc Carreras ; Sandra Pujades; R.Leta; Xavier Alomar; Guillem Pons-LLados |
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Title |
Un Model 3D del Ventricle Esquerre Integrant Anatomia i Funcionalitat |
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Conference Article |
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2008 |
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XX Congrés de la Societat Catalana de Cardiologia, Actes del Congres |
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122 |
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Els canvis en la dinàmica del Ventricle Esquerre (VE) reflecteixen la majoria de malalties cardiovasculars . Els avenços en imatge mèdica han impulsat la recerca en models i simulacions de la dinàmica 3D del VE . La majoria dels models existents sols consideren l’anatomia externa del VE i no permeten una avaluació de l’acoblament electromecànic . Donat que la mecànica d’un muscle depèn de la orientació de les seves fibres, un model realista hauria d’incloure la disposició espacial de la banda ventricular helicoidal (BVH) .
Proposem desenvolupar un model del VE adaptat a cada pacient que integri, per primer cop, l’anatomia de la banda ventricular, l’anatomia externa del VE i la seva funcionalitat, per a una millor determinació del patró d’activació electromecànica |
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Barcelona |
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catalan |
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catalan |
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IAM |
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IAM @ iam @ GGC2008c |
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1504 |
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Author |
Joel Barajas; Jaume Garcia; Karla Lizbeth Caballero; Francesc Carreras; Sandra Pujades; Petia Radeva |
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Correction of Misalignment Artifacts Among 2-D Cardiac MR Images in 3-D Space |
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Conference Article |
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2006 |
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1st International Wokshop on Computer Vision for Intravascular and Intracardiac Imaging (CVII’06) |
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3217 |
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114-121 |
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Cardiac Magnetic Resonance images offer the opportunity to study the heart in detail. One of the main issues in its modelling is to create an accurate 3-D reconstruction of the left ventricle from 2-D views. A first step to achieve this goal is the correct registration among the different image planes due to patient movements. In this article, we present an accurate method to correct displacement artifacts using the Normalized Mutual Information. Here, the image views are treated as planes in order to diminish the approximation error caused by the association of a certain thickness, and moved simultaneously to avoid any kind of bias in the alignment process. This method has been validated using real and syntectic plane displacements, yielding promising results. |
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Copenhagen (Denmark) |
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978-3-540-22977-3 |
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IAM;MILAB |
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IAM @ iam @ BGC2006 |
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1485 |
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Author |
Debora Gil; Petia Radeva |
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Title |
Extending anisotropic operators to recover smooth shapes |
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Journal Article |
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2005 |
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Computer Vision and Image Understanding |
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99 |
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1 |
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110-125 |
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Contour completion; Functional extension; Differential operators; Riemmanian manifolds; Snake segmentation |
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Anisotropic differential operators are widely used in image enhancement processes. Recently, their property of smoothly extending functions to the whole image domain has begun to be exploited. Strong ellipticity of differential operators is a requirement that ensures existence of a unique solution. This condition is too restrictive for operators designed to extend image level sets: their own functionality implies that they should restrict to some vector field. The diffusion tensor that defines the diffusion operator links anisotropic processes with Riemmanian manifolds. In this context, degeneracy implies restricting diffusion to the varieties generated by the vector fields of positive eigenvalues, provided that an integrability condition is satisfied. We will use that any smooth vector field fulfills this integrability requirement to design line connection algorithms for contour completion. As application we present a segmenting strategy that assures convergent snakes whatever the geometry of the object to be modelled is. |
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1077-3142 |
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IAM;MILAB |
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IAM @ iam @ GIR2005 |
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1530 |
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Marta Ligero; Alonso Garcia Ruiz; Cristina Viaplana; Guillermo Villacampa; Maria V Raciti; Jaid Landa; Ignacio Matos; Juan Martin Liberal; Maria Ochoa de Olza; Cinta Hierro; Joaquin Mateo; Macarena Gonzalez; Rafael Morales Barrera; Cristina Suarez; Jordi Rodon; Elena Elez; Irene Braña; Eva Muñoz-Couselo; Ana Oaknin; Roberta Fasani; Paolo Nuciforo; Debora Gil; Carlota Rubio Perez; Joan Seoane; Enriqueta Felip; Manuel Escobar; Josep Tabernero; Joan Carles; Rodrigo Dienstmann; Elena Garralda; Raquel Perez Lopez |
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A CT-based radiomics signature is associated with response to immune checkpoint inhibitors in advanced solid tumors |
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Journal Article |
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2021 |
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Radiology |
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299 |
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1 |
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109-119 |
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Background Reliable predictive imaging markers of response to immune checkpoint inhibitors are needed. Purpose To develop and validate a pretreatment CT-based radiomics signature to predict response to immune checkpoint inhibitors in advanced solid tumors. Materials and Methods In this retrospective study, a radiomics signature was developed in patients with advanced solid tumors (including breast, cervix, gastrointestinal) treated with anti-programmed cell death-1 or programmed cell death ligand-1 monotherapy from August 2012 to May 2018 (cohort 1). This was tested in patients with bladder and lung cancer (cohorts 2 and 3). Radiomics variables were extracted from all metastases delineated at pretreatment CT and selected by using an elastic-net model. A regression model combined radiomics and clinical variables with response as the end point. Biologic validation of the radiomics score with RNA profiling of cytotoxic cells (cohort 4) was assessed with Mann-Whitney analysis. Results The radiomics signature was developed in 85 patients (cohort 1: mean age, 58 years ± 13 [standard deviation]; 43 men) and tested on 46 patients (cohort 2: mean age, 70 years ± 12; 37 men) and 47 patients (cohort 3: mean age, 64 years ± 11; 40 men). Biologic validation was performed in a further cohort of 20 patients (cohort 4: mean age, 60 years ± 13; 14 men). The radiomics signature was associated with clinical response to immune checkpoint inhibitors (area under the curve [AUC], 0.70; 95% CI: 0.64, 0.77; P < .001). In cohorts 2 and 3, the AUC was 0.67 (95% CI: 0.58, 0.76) and 0.67 (95% CI: 0.56, 0.77; P < .001), respectively. A radiomics-clinical signature (including baseline albumin level and lymphocyte count) improved on radiomics-only performance (AUC, 0.74 [95% CI: 0.63, 0.84; P < .001]; Akaike information criterion, 107.00 and 109.90, respectively). Conclusion A pretreatment CT-based radiomics signature is associated with response to immune checkpoint inhibitors, likely reflecting the tumor immunophenotype. © RSNA, 2021 Online supplemental material is available for this article. See also the editorial by Summers in this issue. |
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IAM; 600.145 |
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Admin @ si @ LGV2021 |
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3593 |
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Author |
Joel Barajas; Jaume Garcia; Francesc Carreras; Sandra Pujades; Petia Radeva |
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Title |
Angle Images Using Gabor Filters in Cardiac Tagged MRI |
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Conference Article |
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2005 |
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Proceeding of the 2005 conference on Artificial Intelligence Research and Development |
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107-114 |
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Angle Images, Gabor Filters, Harp, Tagged Mri |
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Tagged Magnetic Resonance Imaging (MRI) is a non-invasive technique used to examine cardiac deformation in vivo. An Angle Image is a representation of a Tagged MRI which recovers the relative position of the tissue respect to the distorted tags. Thus cardiac deformation can be estimated. This paper describes a new approach to generate Angle Images using a bank of Gabor filters in short axis cardiac Tagged MRI. Our method improves the Angle Images obtained by global techniques, like HARP, with a local frequency analysis. We propose to use the phase response of a combination of a Gabor filters bank, and use it to find a more precise deformation of the left ventricle. We demonstrate the accuracy of our method over HARP by several experimental results. |
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Amsterdam; The Netherlands |
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IOS Press |
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Amsterdam, The Netherlands |
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1-58603-560-6 |
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CAIRD |
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BCNPCL @ bcnpcl @ BGC2005; IAM @ iam |
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595 |
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Ole Vilhelm-Larsen; Petia Radeva; Enric Marti |
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Guidelines for choosing optimal parameters of elasticity for snakes |
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1995 |
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Computer Analysis Of Images And Patterns |
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LNCS |
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970 |
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106-113 |
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This paper proposes a guidance in the process of choosing and using the parameters of elasticity of a snake in order to obtain a precise segmentation. A new two step procedure is defined based on upper and lower bounds on the parameters. Formulas, by which these bounds can be calculated for real images where parts of the contour may be missing, are presented. Experiments on segmentation of bone structures in X-ray images have verified the usefulness of the new procedure. |
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Lecture Notes in Computer Science |
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IAM @ iam @ LRM1995b |
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1558 |
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