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Author |
Guillermo Torres; Sonia Baeza; Carles Sanchez; Ignasi Guasch; Antoni Rosell; Debora Gil |
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Title |
An Intelligent Radiomic Approach for Lung Cancer Screening |
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Journal Article |
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2022 |
Publication |
Applied Sciences |
Abbreviated Journal |
APPLSCI |
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Volume |
12 |
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3 |
Pages |
1568 |
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Lung cancer; Early diagnosis; Screening; Neural networks; Image embedding; Architecture optimization |
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Abstract  |
The efficiency of lung cancer screening for reducing mortality is hindered by the high rate of false positives. Artificial intelligence applied to radiomics could help to early discard benign cases from the analysis of CT scans. The available amount of data and the fact that benign cases are a minority, constitutes a main challenge for the successful use of state of the art methods (like deep learning), which can be biased, over-fitted and lack of clinical reproducibility. We present an hybrid approach combining the potential of radiomic features to characterize nodules in CT scans and the generalization of the feed forward networks. In order to obtain maximal reproducibility with minimal training data, we propose an embedding of nodules based on the statistical significance of radiomic features for malignancy detection. This representation space of lesions is the input to a feed
forward network, which architecture and hyperparameters are optimized using own-defined metrics of the diagnostic power of the whole system. Results of the best model on an independent set of patients achieve 100% of sensitivity and 83% of specificity (AUC = 0.94) for malignancy detection. |
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Jan 2022 |
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IAM; 600.139; 600.145 |
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Admin @ si @ TBS2022 |
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3699 |
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Author |
Miquel Angel Piera; Jose Luis Muñoz; Debora Gil; Gonzalo Martin; Jordi Manzano |
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Title |
A Socio-Technical Simulation Model for the Design of the Future Single Pilot Cockpit: An Opportunity to Improve Pilot Performance |
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Journal Article |
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Year |
2022 |
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IEEE Access |
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ACCESS |
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10 |
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22330-22343 |
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Human factors ; Performance evaluation ; Simulation; Sociotechnical systems ; System performance |
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The future deployment of single pilot operations must be supported by new cockpit computer services. Such services require an adaptive context-aware integration of technical functionalities with the concurrent tasks that a pilot must deal with. Advanced artificial intelligence supporting services and improved communication capabilities are the key enabling technologies that will render future cockpits more integrated with the present digitalized air traffic management system. However, an issue in the integration of such technologies is the lack of socio-technical analysis in the design of these teaming mechanisms. A key factor in determining how and when a service support should be provided is the dynamic evolution of pilot workload. This paper investigates how the socio-technical model-based systems engineering approach paves the way for the design of a digital assistant framework by formalizing this workload. The model was validated in an Airbus A-320 cockpit simulator, and the results confirmed the degraded pilot behavioral model and the performance impact according to different contextual flight deck information. This study contributes to practical knowledge for designing human-machine task-sharing systems. |
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Feb 2022 |
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IAM; |
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Admin @ si @ PMG2022 |
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3697 |
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Author |
Paula Fritzsche; C.Roig; Ana Ripoll; Emilio Luque; Aura Hernandez-Sabate |
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Title |
A Performance Prediction Methodology for Data-dependent Parallel Applications |
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Conference Article |
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2006 |
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Proceedings of the IEEE International Conference on Cluster Computing |
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1-8 |
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The increase in the use of parallel distributed architectures in order to solve large-scale scientific problems has generated the need for performance prediction for both deterministic applications and non-deterministic applications. In particular, the performance prediction of data dependent programs is an extremely challenging problem because for a specific issue the input datasets may cause different execution times. Generally, a parallel application is characterized as a collection of tasks and their interrelations. If the application is time-critical it is not enough to work with only one value per task, and consequently knowledge of the distribution of task execution times is crucial. The development of a new prediction methodology to estimate the performance of data-dependent parallel applications is the primary target of this study. This approach makes it possible to evaluate the parallel performance of an application without the need of implementation. A real data-dependent arterial structure detection application model is used to apply the methodology proposed. The predicted times obtained using the new methodology for genuine datasets are compared with predicted times that arise from using only one execution value per task. Finally, the experimental study shows that the new methodology generates more precise predictions. |
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IAM |
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IAM @ iam @ FRR2006 |
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1497 |
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Author |
Petia Radeva; Enric Marti |
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Title |
An improved model of snakes for model-based segmentation |
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Conference Article |
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Year |
1995 |
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Proceedings of Computer Analysis of Images and Patterns |
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515-520 |
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The main advantage of segmentation by snakes consists in its ability to incorporate smoothness constraints on the detected shapes that can occur. Likewise, we propose to model snakes with other properties that reflect the information provided about the object of interest in a different extent. We consider different kinds of snakes, those searching for contours with a certain direction, those preserving an object’s model, those seeking for symmetry, those expanding open, etc. The availability of such a collection of snakes allows not only the more complete use of the knowledge about the segmented object, but also to solve some problems of the existing snakes. Our experiments on segmentation of facial features justify the usefulness of snakes with different properties. |
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CAIP |
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MILAB;IAM |
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IAM @ iam @ RaM1995b |
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1632 |
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Author |
Jaume Garcia; David Rotger; Francesc Carreras; R.Leta; Petia Radeva |
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Title |
Contrast echography segmentation and tracking by trained deformable models |
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Conference Article |
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Year |
2003 |
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Proc. Computers in Cardiology |
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30 |
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173-176 |
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The objective of this work is to segment the human left ventricle myocardium (LVM) in contrast echocardiography imaging and thus track it along a cardiac cycle in order to extract quantitative data about heart function. Ultrasound images are hard to work with due to their speckle appearance. To overcome this we report the combination of active contour models (ACM) or snakes and active shape models (ASM). The ability of ACM in giving closed and smooth curves in addition to the power of the ASM in producing shapes similar to the ones learned, evoke to a robust algorithm. Meanwhile the snake is attracted towards image main features, ASM acts as a correction factor. The algorithm was tested independently on 180 frames and satisfying results were obtained: in 95% the maximum difference between automatic and experts segmentation was less than 12 pixels. |
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Centre de Visió per Computador – Dept. Informàtica, UAB Edifici O – Campus UAB, 08193 Bellater |
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0276-6547 |
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0-7803-8170-X |
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IAM;MILAB |
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IAM @ iam @ GRC2003 |
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1512 |
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Author |
David Roche; Debora Gil; Jesus Giraldo |
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Title |
Multiple active receptor conformation, agonist efficacy and maximum effect of the system: the conformation-based operational model of agonism, |
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Journal Article |
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2013 |
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Drug Discovery Today |
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DDT |
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18 |
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7-8 |
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365-371 |
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The operational model of agonism assumes that the maximum effect a particular receptor system can achieve (the Em parameter) is fixed. Em estimates are above but close to the asymptotic maximum effects of endogenous agonists. The concept of Em is contradicted by superagonists and those positive allosteric modulators that significantly increase the maximum effect of endogenous agonists. An extension of the operational model is proposed that assumes that the Em parameter does not necessarily have a single value for a receptor system but has multiple values associated to multiple active receptor conformations. The model provides a mechanistic link between active receptor conformation and agonist efficacy, which can be useful for the analysis of agonist response under different receptor scenarios. |
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Elsevier |
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IAM; 600.057; 600.054 |
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IAM @ iam @ RGG2013a |
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2190 |
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Author |
David Roche; Debora Gil; Jesus Giraldo |
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Title |
Assessing agonist efficacy in an uncertain Em world |
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Conference Article |
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2012 |
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40th Keystone Symposia on mollecular and celular biology |
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79 |
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The operational model of agonism has been widely used for the analysis of agonist action since its formulation in 1983. The model includes the Em parameter, which is defined as the maximum response of the system. The methods for Em estimation provide Em values not significantly higher than the maximum responses achieved by full agonists. However, it has been found that that some classes of compounds as, for instance, superagonists and positive allosteric modulators can increase the full agonist maximum response, implying upper limits for Em and thereby posing doubts on the validity of Em estimates. Because of the correlation between Em and operational efficacy, τ, wrong Em estimates will yield wrong τ estimates.
In this presentation, the operational model of agonism and various methods for the simulation of allosteric modulation will be analyzed. Alternatives for curve fitting will be presented and discussed. |
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Fairmont Banff Springs, Banff, Alberta, Canada |
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Keystone Symposia |
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Keystone Symposia |
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A. Christopoulus and M. Bouvier |
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english |
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english |
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Keystone Symposia |
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KSMCB |
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IAM |
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IAM @ iam @ RGG2012 |
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1855 |
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Author |
Gemma Sanchez; Josep Llados; Enric Marti |
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Title |
Segmentation and analysis of linial texture in plans |
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Conference Article |
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1997 |
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Actes de la conférence Artificielle et Complexité. |
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Structural Texture, Voronoi, Hierarchical Clustering, String Matching. |
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The problem of texture segmentation and interpretation is one of the main concerns in the field of document analysis. Graphical documents often contain areas characterized by a structural texture whose recognition allows both the document understanding, and its storage in a more compact way. In this work, we focus on structural linial textures of regular repetition contained in plan documents. Starting from an atributed graph which represents the vectorized input image, we develop a method to segment textured areas and recognize their placement rules. We wish to emphasize that the searched textures do not follow a predefined pattern. Minimal closed loops of the input graph are computed, and then hierarchically clustered. In this hierarchical clustering, a distance function between two closed loops is defined in terms of their areas difference and boundary resemblance computed by a string matching procedure. Finally it is noted that, when the texture consists of isolated primitive elements, the same method can be used after computing a Voronoi Tesselation of the input graph. |
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Paris, France |
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Paris |
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AERFAI |
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DAG;IAM; |
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Call Number |
IAM @ iam @ SLM1997 |
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1649 |
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Author |
Josep Llados; Ernest Valveny; Gemma Sanchez; Enric Marti |
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Title |
Symbol recognition: current advances and perspectives |
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Book Chapter |
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2002 |
Publication |
Graphics Recognition Algorithms And Applications |
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LNCS |
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2390 |
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104-128 |
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The recognition of symbols in graphic documents is an intensive research activity in the community of pattern recognition and document analysis. A key issue in the interpretation of maps, engineering drawings, diagrams, etc. is the recognition of domain dependent symbols according to a symbol database. In this work we first review the most outstanding symbol recognition methods from two different points of view: application domains and pattern recognition methods. In the second part of the paper, open and unaddressed problems involved in symbol recognition are described, analyzing their current state of art and discussing future research challenges. Thus, issues such as symbol representation, matching, segmentation, learning, scalability of recognition methods and performance evaluation are addressed in this work. Finally, we discuss the perspectives of symbol recognition concerning to new paradigms such as user interfaces in handheld computers or document database and WWW indexing by graphical content. |
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London, UK |
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Springer-Verlag |
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Dorothea Blostein and Young- Bin Kwon |
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Lecture Notes in Computer Science |
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LNCS |
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3-540-44066-6 |
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GREC |
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DAG; IAM; |
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IAM @ iam @ LVS2002 |
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1572 |
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Author |
Josep Llados; Enric Marti; Juan J.Villanueva |
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Title |
Symbol recognition by error-tolerant subgraph matching between region adjacency graphs |
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Journal Article |
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2001 |
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IEEE Transactions on Pattern Analysis and Machine Intelligence |
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23 |
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10 |
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1137-1143 |
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The recognition of symbols in graphic documents is an intensive research activity in the community of pattern recognition and document analysis. A key issue in the interpretation of maps, engineering drawings, diagrams, etc. is the recognition of domain dependent symbols according to a symbol database. In this work we first review the most outstanding symbol recognition methods from two different points of view: application domains and pattern recognition methods. In the second part of the paper, open and unaddressed problems involved in symbol recognition are described, analyzing their current state of art and discussing future research challenges. Thus, issues such as symbol representation, matching, segmentation, learning, scalability of recognition methods and performance evaluation are addressed in this work. Finally, we discuss the perspectives of symbol recognition concerning to new paradigms such as user interfaces in handheld computers or document database and WWW indexing by graphical content. |
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DAG;IAM;ISE; |
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IAM @ iam @ LMV2001 |
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1581 |
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