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Sandra Pujades;Francesc Carreras;Manuel Ballester; Jaume Garcia; Debora Gil |
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Title |
A Normalized Parametric Domain for the Analysis of the Left Ventricular Function |
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Conference Article |
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2008 |
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Proceedings of the Third International Conference on Computer Vision Theory and Applications (VISAPP’08) |
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1 |
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267-274 |
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Helical Ventricular Myocardial Band; Myocardial Fiber; Tagged Magnetic Resonance; HARP; Optical Flow Variational Framework; Gabor Filters; B-Splines. |
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Impairment of left ventricular (LV) contractility due to cardiovascular diseases is reflected in LV motion patterns. The mechanics of any muscle strongly depends on the spatial orientation of its muscular fibers since the motion that the muscle undergoes mainly takes place along the fiber. The helical ventricular myocardial band (HVMB) concept describes the myocardial muscle as a unique muscular band that twists in space in a non homogeneous fashion. The 3D anisotropy of the ventricular band fibers suggests a regional analysis of the heart motion. Computation of normality models of such motion can help in the detection and localization of any cardiac disorder. In this paper we introduce, for the first time, a normalized parametric domain that allows comparison of the left ventricle motion across patients. We address, both, extraction of the LV motion from Tagged Magnetic Resonance images, as well as, defining a mapping of the LV to a common normalized domain. Extraction of normality motion patterns from 17 healthy volunteers shows the clinical potential of our LV parametrization. |
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IAM @ iam @ GGP2008 |
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1627 |
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Oriol Rodriguez-Leon; Josefina Mauri; Eduard Fernandez-Nofrerias; M.Gomez; Antonio Tovar; L.Cano; C.Diego; Carme Julia; Vicente del Valle; Debora Gil; Petia Radeva |
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Ecografia Intracoronària: Segmentació Automàtica de area de la llum |
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2002 |
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XXXVIII Congreso Nacional de la Sociedad Española de Cardiología. |
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IAM;ADAS;MILAB |
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IAM @ iam @ RMF2002 |
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1638 |
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Oriol Rodriguez-Leon; Debora Gil; Eduard Fernandez-Nofrerias; H.Tizon; S.Montserrat; Vicente del Valle;Josefina Mauri |
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Caracterització de la Perfusió Miocàrdica mitjançant anàlisi estadístic de l espectre en l angiografia de contrast |
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Conference Article |
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2007 |
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XIX Congrés de la Societat Catalana de Cardiologia de Barcelona |
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130 |
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La valoració de la integritat de la microcirculació coronària aporta informació pronòstica en pacients amb infart agut de miocardi en els que es realitza angioplastia primària. Aquesta valoració és subjectiva i presenta una important variabilitat si no es duta a terme per personal experimentat. Presentem una eina d’anàlisi d’imatge que permet fer una valoració de la microcirculació coronària a partir de seqüències d’angiografia. Hem analitzat les variacions locals en el nivell de gris de la imatge durant la seqüència angiogràfica. Hem identificat els principals fenòmens observats (respiració, batec cardíac, tinció arterial, tinció miocàrdica i soroll radiològic) mitjançant un anàlisi estadístic de l’espectre de Fourier de l’evolució al llarg del temps de la mitja local. Aquest mateix anàlisis permet determinat la influència de cadascun d’ells en la extracció del patró de tinció i selecciona la respiració com el fenomen que més distorsiona el patró de tinció original. Els descriptors proposats s’obtenen fora del rang espectral respiratori. Hem testat la seva capacitat per a detectar els tres fenòmens principals (tinció miocàrdica (MS), tinció arterial (AS) i soroll (NS)) independentment de la respiració. La capacitat de discriminació dels descriptors ha estat valorada mitjançant un mètode de crossvalidation en 30 seqüències d’angiografia. Els descriptors emprats permeten caracteritzar la tinció miocàrdica amb una alta eficiència i fiabilitat. A més no hi ha diferències significatives en l’anàlisi de les seqüències obtingudes amb el pacient respirant amb normalitat o en apnea |
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Barcelona (Spain) |
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IAM @ iam @ RGF2007 |
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1639 |
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Oriol Rodriguez-Leon; Eduard Fernandez-Nofrerias; Josefina Mauri; Vicente del Valle; Debora Gil; A.Barrios; E.Garcia; Petia Radeva |
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Perfusion ratio: A new tool to objectively assess microcirculation perfusion after primary Percutaneous Coronary Intervention |
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2006 |
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World Congress of Cardiology |
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859 |
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Barcelona (Spain) |
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IAM @ iam @ RFM2006c |
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1643 |
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Oriol Rodriguez-Leon; Josefina Mauri; Eduard Fernandez-Nofrerias; Vicente de Valle; E.Garcia; A.Barrios; Debora Gil; Petia Radeva |
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Analysis of the changes in angiography local grey-level values to determine myocardial perfusion |
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Conference Article |
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2006 |
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World Congress of Cardiology |
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862 |
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IAM @ iam @ RMF2006 |
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1644 |
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Aura Hernandez-Sabate; Debora Gil; David Roche; Monica M. S. Matsumoto; Sergio S. Furuie |
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Inferring the Performance of Medical Imaging Algorithms |
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2011 |
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14th International Conference on Computer Analysis of Images and Patterns |
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6854 |
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520-528 |
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Validation, Statistical Inference, Medical Imaging Algorithms. |
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Evaluation of the performance and limitations of medical imaging algorithms is essential to estimate their impact in social, economic or clinical aspects. However, validation of medical imaging techniques is a challenging task due to the variety of imaging and clinical problems involved, as well as, the difficulties for systematically extracting a reliable solely ground truth. Although specific validation protocols are reported in any medical imaging paper, there are still two major concerns: definition of standardized methodologies transversal to all problems and generalization of conclusions to the whole clinical data set.
We claim that both issues would be fully solved if we had a statistical model relating ground truth and the output of computational imaging techniques. Such a statistical model could conclude to what extent the algorithm behaves like the ground truth from the analysis of a sampling of the validation data set. We present a statistical inference framework reporting the agreement and describing the relationship of two quantities. We show its transversality by applying it to validation of two different tasks: contour segmentation and landmark correspondence. |
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Sevilla |
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Springer-Verlag Berlin Heidelberg |
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Berlin |
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Pedro Real; Daniel Diaz-Pernil; Helena Molina-Abril; Ainhoa Berciano; Walter Kropatsch |
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CAIP |
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IAM @ iam @ HGR2011 |
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1676 |
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David Roche; Debora Gil; Jesus Giraldo |
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Using statistical inference for designing termination conditions ensuring convergence of Evolutionary Algorithms |
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2011 |
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11th European Conference on Artificial Life |
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A main challenge in Evolutionary Algorithms (EAs) is determining a termination condition ensuring stabilization close to the optimum in real-world applications. Although for known test functions distribution-based quantities are good candidates (as far as suitable parameters are used), in real-world problems an open question still remains unsolved. How can we estimate an upper-bound for the termination condition value ensuring a given accuracy for the (unknown) EA solution?
We claim that the termination problem would be fully solved if we defined a quantity (depending only on the EA output) behaving like the solution accuracy. The open question would be, then, satisfactorily answered if we had a model relating both quantities, since accuracy could be predicted from the alternative quantity. We present a statistical inference framework addressing two topics: checking the correlation between the two quantities and defining a regression model for predicting (at a given confidence level) accuracy values from the EA output. |
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Paris, France |
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ECAL |
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IAM @ iam @ RGG2011b |
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1678 |
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Ferran Poveda; Debora Gil ;Albert Andaluz ;Enric Marti |
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Multiscale Tractography for Representing Heart Muscular Architecture |
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2011 |
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In MICCAI 2011 Workshop on Computational Diffusion MRI |
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Deep understanding of myocardial structure of the heart would unravel crucial knowledge for clinical and medical procedures. Although the muscular architecture of the heart has been debated by countless researchers, the controversy is still alive. Diffusion Tensor MRI, DT-MRI, is a unique imaging technique for computational validation of the muscular structure of the heart. By the complex arrangement of myocites, existing techniques can not provide comprehensive descriptions of the global muscular architecture. In this paper we introduce a multiresolution reconstruction technique based on DT-MRI streamlining for simplified global myocardial model generation. Our reconstructions can restore the most complex myocardial structures and indicate a global helical organization |
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CDRMI |
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IAM @ iam @ PGA2011 |
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1681 |
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Patricia Marquez; Debora Gil; Aura Hernandez-Sabate |
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A Confidence Measure for Assessing Optical Flow Accuracy in the Absence of Ground Truth |
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2011 |
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IEEE International Conference on Computer Vision – Workshops |
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2042-2049 |
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IEEE International Conference on Computer Vision – Workshops |
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Optical flow is a valuable tool for motion analysis in autonomous navigation systems. A reliable application requires determining the accuracy of the computed optical flow. This is a main challenge given the absence of ground truth in real world sequences. This paper introduces a measure of optical flow accuracy for Lucas-Kanade based flows in terms of the numerical stability of the data-term. We call this measure optical flow condition number. A statistical analysis over ground-truth data show a good statistical correlation between the condition number and optical flow error. Experiments on driving sequences illustrate its potential for autonomous navigation systems. |
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IEEE |
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Barcelona (Spain) |
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ICCVW |
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IAM @ iam @ MGH2011 |
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1682 |
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David Roche; Debora Gil; Jesus Giraldo |
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Assessing agonist efficacy in an uncertain Em world |
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2012 |
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40th Keystone Symposia on mollecular and celular biology |
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79 |
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The operational model of agonism has been widely used for the analysis of agonist action since its formulation in 1983. The model includes the Em parameter, which is defined as the maximum response of the system. The methods for Em estimation provide Em values not significantly higher than the maximum responses achieved by full agonists. However, it has been found that that some classes of compounds as, for instance, superagonists and positive allosteric modulators can increase the full agonist maximum response, implying upper limits for Em and thereby posing doubts on the validity of Em estimates. Because of the correlation between Em and operational efficacy, τ, wrong Em estimates will yield wrong τ estimates.
In this presentation, the operational model of agonism and various methods for the simulation of allosteric modulation will be analyzed. Alternatives for curve fitting will be presented and discussed. |
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Fairmont Banff Springs, Banff, Alberta, Canada |
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Keystone Symposia |
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Keystone Symposia |
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A. Christopoulus and M. Bouvier |
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english |
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KSMCB |
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IAM @ iam @ RGG2012 |
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1855 |
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