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Author |
Debora Gil; Petia Radeva |
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Title  |
Inhibition of False Landmarks |
Type |
Book Chapter |
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Year |
2004 |
Publication |
Recent Advances in Artificial Intelligence Research and Development |
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Pages |
233-244 |
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Abstract |
We argue that a corner detector should be based on the degree of continuity of the tangent vector to the image level sets, work on the image domain and need no assumptions on neither the image local structure nor the particular geometry of the corner/junction. An operator measuring the degree of differentiability of the projection matrix on the image gradient fulfills the above requirements. Its high sensitivity to changes in vector directions makes it suitable for landmark location in real images prone to need smoothing to reduce the impact of noise. Because using smoothing kernels leads to corner misplacement, we suggest an alternative fake response remover based on the receptive field inhibition of spurious details. The combination of both orientation discontinuity detection and noise inhibition produce our Inhibition Orientation Energy (IOE) landmark locator. |
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IOS Press |
Place of Publication |
Barcelona (Spain) |
Editor |
al, J.V. et |
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IAM;MILAB |
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Call Number |
IAM @ iam @ GiR2004a |
Serial |
1533 |
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Author |
David Roche; Debora Gil; Jesus Giraldo |
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Title |
Mathematical modeling of G protein-coupled receptor function: What can we learn from empirical and mechanistic models? |
Type |
Book Chapter |
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Year |
2014 |
Publication |
G Protein-Coupled Receptors – Modeling and Simulation Advances in Experimental Medicine and Biology |
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Volume |
796 |
Issue |
3 |
Pages |
159-181 |
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Keywords |
β-arrestin; biased agonism; curve fitting; empirical modeling; evolutionary algorithm; functional selectivity; G protein; GPCR; Hill coefficient; intrinsic efficacy; inverse agonism; mathematical modeling; mechanistic modeling; operational model; parameter optimization; receptor dimer; receptor oligomerization; receptor constitutive activity; signal transduction; two-state model |
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Abstract |
Empirical and mechanistic models differ in their approaches to the analysis of pharmacological effect. Whereas the parameters of the former are not physical constants those of the latter embody the nature, often complex, of biology. Empirical models are exclusively used for curve fitting, merely to characterize the shape of the E/[A] curves. Mechanistic models, on the contrary, enable the examination of mechanistic hypotheses by parameter simulation. Regretfully, the many parameters that mechanistic models may include can represent a great difficulty for curve fitting, representing, thus, a challenge for computational method development. In the present study some empirical and mechanistic models are shown and the connections, which may appear in a number of cases between them, are analyzed from the curves they yield. It may be concluded that systematic and careful curve shape analysis can be extremely useful for the understanding of receptor function, ligand classification and drug discovery, thus providing a common language for the communication between pharmacologists and medicinal chemists. |
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Springer Netherlands |
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ISSN |
0065-2598 |
ISBN |
978-94-007-7422-3 |
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Notes |
IAM; 600.075 |
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Call Number |
IAM @ iam @ RGG2014 |
Serial |
2197 |
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Author |
H. Martin ; Jens Fagertun; Sergio Vera; Debora Gil |
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Title |
Medial structure generation for registration of anatomical structures |
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Book Chapter |
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Year |
2017 |
Publication |
Skeletonization, Theory, Methods and Applications |
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11 |
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IAM; 600.096; 600.075; 600.145 |
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Call Number |
Admin @ si @ MFV2017a |
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2935 |
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Author |
Sergio Vera; Miguel Angel Gonzalez Ballester; Debora Gil |
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Title |
Optimal Medial Surface Generation for Anatomical Volume Representations |
Type |
Book Chapter |
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Year |
2012 |
Publication |
Abdominal Imaging. Computational and Clinical Applications |
Abbreviated Journal |
LNCS |
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7601 |
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265-273 |
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Keywords |
Medial surface representation; volume reconstruction |
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Abstract |
Medial representations are a widely used technique in abdominal organ shape representation and parametrization. Those methods require good medial manifolds as a starting point. Any medial
surface used to parametrize a volume should be simple enough to allow an easy manipulation and complete enough to allow an accurate reconstruction of the volume. Obtaining good quality medial
surfaces is still a problem with current iterative thinning methods. This forces the usage of generic, pre-calculated medial templates that are adapted to the final shape at the cost of a drop in volume reconstruction.
This paper describes an operator for generation of medial structures that generates clean and complete manifolds well suited for their further use in medial representations of abdominal organ volumes. While being simpler than thinning surfaces, experiments show its high performance in volume reconstruction and preservation of medial surface main branching topology. |
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Address |
Nice, France |
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Springer Berlin Heidelberg |
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Editor |
Yoshida, Hiroyuki and Hawkes, David and Vannier, MichaelW. |
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Lecture Notes in Computer Science |
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ISSN |
0302-9743 |
ISBN |
978-3-642-33611-9 |
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STACOM |
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Call Number |
IAM @ iam @ VGG2012b |
Serial |
1988 |
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Author |
Misael Rosales; Petia Radeva; Oriol Rodriguez; Debora Gil |
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Title |
Suppression of IVUS Image Rotation. A Kinematic Approach |
Type |
Book Chapter |
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Year |
2005 |
Publication |
Functional Imaging and Modeling of the Heart |
Abbreviated Journal |
LNCS |
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3504 |
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Pages |
889-892 |
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Abstract |
IntraVascular Ultrasound (IVUS) is an exploratory technique used in interventional procedures that shows cross section images of arteries and provides qualitative information about the causes and severity of the arterial lumen narrowing. Cross section analysis as well as visualization of plaque extension in a vessel segment during the catheter imaging pullback are the technique main advantages. However, IVUS sequence exhibits a periodic rotation artifact that makes difficult the longitudinal lesion inspection and hinders any segmentation algorithm. In this paper we propose a new kinematic method to estimate and remove the image rotation of IVUS images sequences. Results on several IVUS sequences show good results and prompt some of the clinical applications to vessel dynamics study, and relation to vessel pathology. |
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Publisher |
Springer Berlin / Heidelberg |
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Editor |
Frangi, Alejandro and Radeva, Petia and Santos, Andres and Hernandez, Monica |
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Series Title |
Lecture Notes in Computer Science |
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LNCS |
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3504 |
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IAM;MILAB |
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no |
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Call Number |
IAM @ iam @ RRR2005 |
Serial |
1645 |
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Author |
Aura Hernandez-Sabate; Debora Gil |
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Title |
The Benefits of IVUS Dynamics for Retrieving Stable Models of Arteries |
Type |
Book Chapter |
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Year |
2012 |
Publication |
Intravascular Ultrasound |
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Pages |
185-206 |
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Publisher |
Intech |
Place of Publication |
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Editor |
Yasuhiro Honda |
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Language |
English |
Summary Language |
english |
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978-953-307-900-4 |
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Notes |
IAM; ADAS |
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no |
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Call Number |
IAM @ iam @ HeG2012 |
Serial |
1684 |
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Author |
Debora Gil; Oriol Ramos Terrades; Raquel Perez |
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Title |
Topological Radiomics (TOPiomics): Early Detection of Genetic Abnormalities in Cancer Treatment Evolution |
Type |
Book Chapter |
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Year |
2021 |
Publication |
Extended Abstracts GEOMVAP 2019, Trends in Mathematics 15 |
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15 |
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89–93 |
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Abstract |
Abnormalities in radiomic measures correlate to genomic alterations prone to alter the outcome of personalized anti-cancer treatments. TOPiomics is a new method for the early detection of variations in tumor imaging phenotype from a topological structure in multi-view radiomic spaces. |
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Springer Nature |
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IAM; DAG; 600.120; 600.145; 600.139 |
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Call Number |
Admin @ si @ GRP2021 |
Serial |
3594 |
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