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Author |
Debora Gil; Carles Sanchez; Agnes Borras; Marta Diez-Ferrer; Antoni Rosell |
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Title |
Segmentation of Distal Airways using Structural Analysis |
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2019 |
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PloS one |
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Plos |
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14 |
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12 |
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Segmentation of airways in Computed Tomography (CT) scans is a must for accurate support of diagnosis and intervention of many pulmonary disorders. In particular, lung cancer diagnosis would benefit from segmentations reaching most distal airways. We present a method that combines descriptors of bronchi local appearance and graph global structural analysis to fine-tune thresholds on the descriptors adapted for each bronchial level. We have compared our method to the top performers of the EXACT09 challenge and to a commercial software for biopsy planning evaluated in an own-collected data-base of high resolution CT scans acquired under different breathing conditions. Results on EXACT09 data show that our method provides a high leakage reduction with minimum loss in airway detection. Results on our data-base show the reliability across varying breathing conditions and a competitive performance for biopsy planning compared to a commercial solution. |
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IAM; 600.139; 600.145 |
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Admin @ si @ GSB2019 |
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3357 |
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Jose Elias Yauri; M. Lagos; H. Vega-Huerta; P. de-la-Cruz; G.L.E Maquen-Niño; E. Condor-Tinoco |
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Title |
Detection of Epileptic Seizures Based-on Channel Fusion and Transformer Network in EEG Recordings |
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Journal Article |
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Year |
2023 |
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International Journal of Advanced Computer Science and Applications |
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IJACSA |
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14 |
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5 |
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1067-1074 |
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Epilepsy; epilepsy detection; EEG; EEG channel fusion; convolutional neural network; self-attention |
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According to the World Health Organization, epilepsy affects more than 50 million people in the world, and specifically, 80% of them live in developing countries. Therefore, epilepsy has become among the major public issue for many governments and deserves to be engaged. Epilepsy is characterized by uncontrollable seizures in the subject due to a sudden abnormal functionality of the brain. Recurrence of epilepsy attacks change people’s lives and interferes with their daily activities. Although epilepsy has no cure, it could be mitigated with an appropriated diagnosis and medication. Usually, epilepsy diagnosis is based on the analysis of an electroencephalogram (EEG) of the patient. However, the process of searching for seizure patterns in a multichannel EEG recording is a visual demanding and time consuming task, even for experienced neurologists. Despite the recent progress in automatic recognition of epilepsy, the multichannel nature of EEG recordings still challenges current methods. In this work, a new method to detect epilepsy in multichannel EEG recordings is proposed. First, the method uses convolutions to perform channel fusion, and next, a self-attention network extracts temporal features to classify between interictal and ictal epilepsy states. The method was validated in the public CHB-MIT dataset using the k-fold cross-validation and achieved 99.74% of specificity and 99.15% of sensitivity, surpassing current approaches. |
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IAM |
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Admin @ si @ |
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3856 |
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Mireia Sole; Joan Blanco; Debora Gil; G. Fonseka; Richard Frodsham; Francesca Vidal; Zaida Sarrate |
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Title |
Noves perspectives en l estudi de la territorialitat cromosomica de cel·lules germinals masculines: estudis tridimensionals |
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2017 |
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Biologia de la Reproduccio |
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JBR |
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15 |
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73-78 |
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In somatic cells, chromosomes occupy specific nuclear regions called chromosome territories which are involved in the
maintenance and regulation of the genome. Preliminary data in male germ cells also suggest the importance of chromosome
territoriality in cell functionality. Nevertheless, the specific characteristics of testicular tissue (presence of different
cell types with different morphological characteristics, in different stages of development and with different ploidy)
makes difficult to achieve conclusive results. In this study we have developed a methodology to approach the threedimensional
study of all chromosome territories in male germ cells from C57BL/6J mice (Mus musculus). The method
includes the following steps: i) Optimized cell fixation to obtain an optimal preservation of the three-dimensionality cell
morphology, ii) Chromosome identification by FISH (Chromoprobe Multiprobe® OctoChrome™ Murine System; Cytocell)
and confocal microscopy (TCS-SP5, Leica Microsystems), iii) Cell type identification by immunofluorescence
iv) Image analysis using Matlab scripts, v) Numerical data extraction related to chromosome features, chromosome
radial position and chromosome relative position. This methodology allows the unequivocally identification and the
analysis of the chromosome territories of all spermatogenic stages. Results will provide information about the features
that determine chromosomal position, preferred associations between chromosomes, and the relationship between chromosome
positioning and genome regulation. |
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978-84-697-3767-5 |
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IAM; 600.096; 600.145 |
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no |
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Admin @ si @ SBG2017c |
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2961 |
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Author |
Guillermo Torres; Debora Gil |
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Title |
A multi-shape loss function with adaptive class balancing for the segmentation of lung structures |
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Journal Article |
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2020 |
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International Journal of Computer Assisted Radiology and Surgery |
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IJCAR |
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15 |
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1 |
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S154-55 |
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IAM |
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no |
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Admin @ si @ ToG2020 |
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3590 |
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Author |
Debora Gil; Oriol Ramos Terrades; Raquel Perez |
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Title |
Topological Radiomics (TOPiomics): Early Detection of Genetic Abnormalities in Cancer Treatment Evolution |
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Book Chapter |
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Year |
2021 |
Publication |
Extended Abstracts GEOMVAP 2019, Trends in Mathematics 15 |
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15 |
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89–93 |
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Abnormalities in radiomic measures correlate to genomic alterations prone to alter the outcome of personalized anti-cancer treatments. TOPiomics is a new method for the early detection of variations in tumor imaging phenotype from a topological structure in multi-view radiomic spaces. |
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Springer Nature |
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IAM; DAG; 600.120; 600.145; 600.139 |
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no |
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Admin @ si @ GRP2021 |
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3594 |
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Author |
Juan Borrego-Carazo; Carles Sanchez; David Castells; Jordi Carrabina; Debora Gil |
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A benchmark for the evaluation of computational methods for bronchoscopic navigation |
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2022 |
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International Journal of Computer Assisted Radiology and Surgery |
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IJCARS |
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17 |
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1 |
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IAM |
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Admin @ si @ BSC2022 |
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3832 |
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Antoni Rosell; Sonia Baeza; S. Garcia-Reina; JL. Mate; Ignasi Guasch; I. Nogueira; I. Garcia-Olive; Guillermo Torres; Carles Sanchez; Debora Gil |
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EP01.05-001 Radiomics to Increase the Effectiveness of Lung Cancer Screening Programs. Radiolung Preliminary Results |
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Journal Article |
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2022 |
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Journal of Thoracic Oncology |
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JTO |
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17 |
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9 |
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S182 |
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IAM |
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Admin @ si @ RBG2022b |
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3834 |
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Author |
Josep Llados; Horst Bunke; Enric Marti |
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Title |
Finding rotational symmetries by cyclic string matching |
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1997 |
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Pattern recognition letters |
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PRL |
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18 |
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14 |
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1435-1442 |
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Rotational symmetry; Reflectional symmetry; String matching |
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Symmetry is an important shape feature. In this paper, a simple and fast method to detect perfect and distorted rotational symmetries of 2D objects is described. The boundary of a shape is polygonally approximated and represented as a string. Rotational symmetries are found by cyclic string matching between two identical copies of the shape string. The set of minimum cost edit sequences that transform the shape string to a cyclically shifted version of itself define the rotational symmetry and its order. Finally, a modification of the algorithm is proposed to detect reflectional symmetries. Some experimental results are presented to show the reliability of the proposed algorithm |
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Elsevier |
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DAG;IAM; |
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IAM @ iam @ LBM1997a |
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1562 |
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David Roche; Debora Gil; Jesus Giraldo |
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Multiple active receptor conformation, agonist efficacy and maximum effect of the system: the conformation-based operational model of agonism, |
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2013 |
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Drug Discovery Today |
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DDT |
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18 |
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7-8 |
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365-371 |
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The operational model of agonism assumes that the maximum effect a particular receptor system can achieve (the Em parameter) is fixed. Em estimates are above but close to the asymptotic maximum effects of endogenous agonists. The concept of Em is contradicted by superagonists and those positive allosteric modulators that significantly increase the maximum effect of endogenous agonists. An extension of the operational model is proposed that assumes that the Em parameter does not necessarily have a single value for a receptor system but has multiple values associated to multiple active receptor conformations. The model provides a mechanistic link between active receptor conformation and agonist efficacy, which can be useful for the analysis of agonist response under different receptor scenarios. |
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Elsevier |
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IAM; 600.057; 600.054 |
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IAM @ iam @ RGG2013a |
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2190 |
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Author |
Aura Hernandez-Sabate; Lluis Albarracin; F. Javier Sanchez |
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Title |
Graph-Based Problem Explorer: A Software Tool to Support Algorithm Design Learning While Solving the Salesperson Problem |
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2020 |
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Mathematics |
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MATH |
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20 |
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8(9) |
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1595 |
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STEM education; Project-based learning; Coding; software tool |
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In this article, we present a sequence of activities in the form of a project in order to promote
learning on design and analysis of algorithms. The project is based on the resolution of a real problem, the salesperson problem, and it is theoretically grounded on the fundamentals of mathematical modelling. In order to support the students’ work, a multimedia tool, called Graph-based Problem Explorer (GbPExplorer), has been designed and refined to promote the development of computer literacy in engineering and science university students. This tool incorporates several modules to allow coding different algorithmic techniques solving the salesman problem. Based on an educational design research along five years, we observe that working with GbPExplorer during the project provides students with the possibility of representing the situation to be studied in the form of graphs and analyze them from a computational point of view. |
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September 2020 |
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IAM; ISE |
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Admin @ si @ |
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3722 |
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