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Carles Sanchez, Jorge Bernal, Debora Gil, & F. Javier Sanchez. (2013). "On-line lumen centre detection in gastrointestinal and respiratory endoscopy " In Klaus Miguel Angel and Drechsler Stefan and González Ballester Raj and Wesarg Cristina and Shekhar Marius George and Oyarzun Laura M. and L. Erdt (Ed.), Second International Workshop Clinical Image-Based Procedures (Vol. 8361, pp. 31–38). Springer International Publishing.
Abstract: We present in this paper a novel lumen centre detection for gastrointestinal and respiratory endoscopic images. The proposed method is based on the appearance and geometry of the lumen, which we defined as the darkest image region which centre is a hub of image gradients. Experimental results validated on the first public annotated gastro-respiratory database prove the reliability of the method for a wide range of images (with precision over 95 %).
Keywords: Lumen centre detection; Bronchoscopy; Colonoscopy
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Debora Gil, Aura Hernandez-Sabate, Antoni Carol, Oriol Rodriguez, & Petia Radeva. (2005). "A Deterministic-Statistic Adventitia Detection in IVUS Images " In 3rd International workshop on International Workshop on Functional Imaging and Modeling of the Heart (pp. 65–74).
Abstract: Plaque analysis in IVUS planes needs accurate intima and adventitia models. Large variety in adventitia descriptors difficulties its detection and motivates using a classification strategy for selecting points on the structure. Whatever the set of descriptors used, the selection stage suffers from fake responses due to noise and uncompleted true curves. In order to smooth background noise while strengthening responses, we apply a restricted anisotropic filter that homogenizes grey levels along the image significant structures. Candidate points are extracted by means of a simple semi supervised adaptive classification of the filtered image response to edge and calcium detectors. The final model is obtained by interpolating the former line segments with an anisotropic contour closing technique based on functional extension principles.
Keywords: Electron microscopy; Unbending; 2D crystal; Interpolation; Approximation
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Debora Gil, Jaume Garcia, Mariano Vazquez, Ruth Aris, & Guilleaume Houzeaux. (2008). "Patient-Sensitive Anatomic and Functional 3D Model of the Left Ventricle Function " In 8th World Congress on Computational Mechanichs (WCCM8).
Abstract: Early diagnosis and accurate treatment of Left Ventricle (LV) dysfunction significantly increases the patient survival. Impairment of LV contractility due to cardiovascular diseases is reflected in its motion patterns. Recent advances in medical imaging, such as Magnetic Resonance (MR), have encouraged research on 3D simulation and modelling of the LV dynamics. Most of the existing 3D models [1] consider just the gross anatomy of the LV and restore a truncated ellipse which deforms along the cardiac cycle. The contraction mechanics of any muscle strongly depends on the spatial orientation of its muscular fibers since the motion that the muscle undergoes mainly takes place along the fibers. It follows that such simplified models do not allow evaluation of the heart electro-mechanical function and coupling, which has recently risen as the key point for understanding the LV functionality [2]. In order to thoroughly understand the LV mechanics it is necessary to consider the complete anatomy of the LV given by the orientation of the myocardial fibres in 3D space as described by Torrent Guasp [3].
We propose developing a 3D patient-sensitive model of the LV integrating, for the first time, the ven- tricular band anatomy (fibers orientation), the LV gross anatomy and its functionality. Such model will represent the LV function as a natural consequence of its own ventricular band anatomy. This might be decisive in restoring a proper LV contraction in patients undergoing pace marker treatment.
The LV function is defined as soon as the propagation of the contractile electromechanical pulse has been modelled. In our experiments we have used the wave equation for the propagation of the electric pulse. The electromechanical wave moves on the myocardial surface and should have a conductivity tensor oriented along the muscular fibers. Thus, whatever mathematical model for electric pulse propa- gation [4] we consider, the complete anatomy of the LV should be extracted.
The LV gross anatomy is obtained by processing multi slice MR images recorded for each patient. Information about the myocardial fibers distribution can only be extracted by Diffusion Tensor Imag- ing (DTI), which can not provide in vivo information for each patient. As a first approach, we have
Figure 1: Scheme for the Left Ventricle Patient-Sensitive Model.
computed an average model of fibers from several DTI studies of canine hearts. This rough anatomy is the input for our electro-mechanical propagation model simulating LV dynamics. The average fiber orientation is updated until the simulated LV motion agrees with the experimental evidence provided by the LV motion observed in tagged MR (TMR) sequences. Experimental LV motion is recovered by applying image processing, differential geometry and interpolation techniques to 2D TMR slices [5]. The pipeline in figure 1 outlines the interaction between simulations and experimental data leading to our patient-tailored model.
Keywords: Left Ventricle, Electromechanical Models, Image Processing, Magnetic Resonance.
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C. Santa-Marta, Jaume Garcia, A. Bajo, J.J. Vaquero, M. Ledesma-Carbayo, & Debora Gil. (2008)." Influence of the Temporal Resolution on the Quantification of Displacement Fields in Cardiac Magnetic Resonance Tagged Images" In S. A. Roberto hornero (Ed.), XXVI Congreso Anual de la Sociedad Española de Ingenieria Biomedica (352–353).
Abstract: It is difficult to acquire tagged cardiac MR images with a high temporal and spatial resolution using clinical MR scanners. However, if such images are used for quantifying scores based on motion, it is essential a resolution as high as possibl e. This paper explores the influence of the temporal resolution of a tagged series on the quantification of myocardial dynamic parameters. To such purpose we have designed a SPAMM (Spatial Modulation of Magnetization) sequence allowing acquisition of sequences at simple and double temporal resolution. Sequences are processed to compute myocardial motion by an automatic technique based on the tracking of the harmonic phase of tagged images (the Harmonic Phase Flow, HPF). The results have been compared to manual tracking of myocardial tags. The error in displacement fields for double resolution sequences reduces 17%.
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Cristina Cañero, Petia Radeva, Oriol Pujol, Ricardo Toledo, Debora Gil, J. Saludes, et al. (1999). "Optimal Stent Implantation: Three-dimensional Evaluation of the Mutual Position of Stent and Vessel via Intracoronary Ecography " In Proceedings of International Conference on Computer in Cardiology (CIC´99).
Abstract: We present a new automatic technique to visualize and quantify the mutual position between the stent and the vessel wall by considering their three-dimensional reconstruction. Two deformable generalized cylinders adapt to the image features in all IVUS planes corresponding to the vessel wall and the stent in order to reconstruct the boundaries of the stent and the vessel in space. The image features that characterize the stent and the vessel wall are determined in terms of edge and ridge image detectors taking into account the gray level of the image pixels. We show that the 30 reconstruction by deformable cylinders is accurate and robust due to the spatial data coherence in the considered volumetric IVUS image. The main clinic utility of the stent and vessel reconstruction by deformable’ cylinders consists of its possibility to visualize and to assess the optimal stent introduction.
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Cristina Cañero, Petia Radeva, Oriol Pujol, Ricardo Toledo, Debora Gil, J. Saludes, et al. (1999). "Three-dimensional reconstruction and quantification of the coronary tree using intravascular ultrasound images " In Proceedings of International Conference on Computer in Cardiology (CIC´99).
Abstract: In this paper we propose a new Computer Vision technique to reconstruct the vascular wall in space using a deformable model-based technique and compounding methods, based in biplane angiography and intravascular ultrasound data jicsion. It is also proposed a generalpurpose three-dimensional guided interpolation method. The three dimensional centerline of the vessel is reconstructed from geometrically corrected biplane angiographies using automatic segmentation methods and snakes. The IVUS image planes are located in the threedimensional space and correctly oriented. A led interpolation method based in B-SurJaces and snakes isused to fill the gaps among image planes
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Jaume Garcia, Debora Gil, Francesc Carreras, Sandra Pujades, R.Leta, Xavier Alomar, et al. (2008). "Un Model 3D del Ventricle Esquerre Integrant Anatomia i Funcionalitat " In XX Congrés de la Societat Catalana de Cardiologia, Actes del Congres (122). Barcelona.
Abstract: Els canvis en la dinàmica del Ventricle Esquerre (VE) reflecteixen la majoria de malalties cardiovasculars . Els avenços en imatge mèdica han impulsat la recerca en models i simulacions de la dinàmica 3D del VE . La majoria dels models existents sols consideren l’anatomia externa del VE i no permeten una avaluació de l’acoblament electromecànic . Donat que la mecànica d’un muscle depèn de la orientació de les seves fibres, un model realista hauria d’incloure la disposició espacial de la banda ventricular helicoidal (BVH) .
Proposem desenvolupar un model del VE adaptat a cada pacient que integri, per primer cop, l’anatomia de la banda ventricular, l’anatomia externa del VE i la seva funcionalitat, per a una millor determinació del patró d’activació electromecànica
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Jaume Garcia, Debora Gil, Francesc Carreras, Sandra Pujades, & R.Leta. (2007). "Modelització 4-Dimensional de la Funció Siatólica del Ventricle Esquerre " In XIX Congrés de la Societat Catalana de Cardiologia de Barcelona (pp. 133–134). Barcelona (Spain).
Abstract: L’evolució tecnològica en el tractament de les imatges mèdiques permet reconstruir, amb el software apropiat, imatges tridimensionals de les estructures cardiovasculars i dotar-les de moviment. Les imatges 4D resultants faciliten l’estudi de la fisiopatologia de la insuficiència cardíaca en base als transtorns de l’activació electromecànica ventricular, el que pot ser d’interès en el procés de selecció de pacients candidats a teràpies de resincronització. Presentem els resultats preliminars de la reconstrucció 4D del ventricle esquerre (VE) a partir de les seqüències de tagging miocàrdic del VE.
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Jaume Garcia, Debora Gil, Joel Barajas, Francesc Carreras, Sandra Pujades, & Petia Radeva. (2006). "Characterization of ventricular torsion in healthy subjects using Gabor filters and a variational framework " In Proc. Computers in Cardiology (pp. 877–880).
Abstract: In this work, we present a fully automated method for tissue deformation estimation in tagged magnetic resonance images (TMRI). Gabor filter banks, tuned independently for each left ventricle level, provide optimally filtered complex images which phase remains constant along the cardiac cycle. This fact can be thought as the brightness constancy condition required by classical optical flow (OF) methods. Pairs of these filtered sequences, together with a variational formulation are used in a second step to obtain dense continuous deformation maps that we call Harmonic Phase Flow. This method has been used to determine reference values of ventricular torsion (VT) in a set of 8 healthy volunteers. The results encourage the use of VT as a useful parameter for ventricular function assessment in clinical routine.
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M. Gomez, J. Mauri, Eduard Fernandez-Nofrerias, Oriol Rodriguez-Leor, Carme Julia, Debora Gil, et al. (2002)." Reconstrucción de un modelo espacio-temporal de la luz del vaso a partir de secuencias de ecografía intracoronaria" In XXXVIII Congreso Nacional de la Sociedad Española de Cardiología..
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