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Esmitt Ramirez, Carles Sanchez, Agnes Borras, Marta Diez-Ferrer, Antoni Rosell, & Debora Gil. (2018). "Image-Based Bronchial Anatomy Codification for Biopsy Guiding in Video Bronchoscopy " In OR 2.0 Context-Aware Operating Theaters, Computer Assisted Robotic Endoscopy, Clinical Image-Based Procedures, and Skin Image Analysis (Vol. 11041).
Abstract: Bronchoscopy examinations allow biopsy of pulmonary nodules with minimum risk for the patient. Even for experienced bronchoscopists, it is difficult to guide the bronchoscope to most distal lesions and obtain an accurate diagnosis. This paper presents an image-based codification of the bronchial anatomy for bronchoscopy biopsy guiding. The 3D anatomy of each patient is codified as a binary tree with nodes representing bronchial levels and edges labeled using their position on images projecting the 3D anatomy from a set of branching points. The paths from the root to leaves provide a codification of navigation routes with spatially consistent labels according to the anatomy observes in video bronchoscopy explorations. We evaluate our labeling approach as a guiding system in terms of the number of bronchial levels correctly codified, also in the number of labels-based instructions correctly supplied, using generalized mixed models and computer-generated data. Results obtained for three independent observers prove the consistency and reproducibility of our guiding system. We trust that our codification based on viewer’s projection might be used as a foundation for the navigation process in Virtual Bronchoscopy systems.
Keywords: Biopsy guiding; Bronchoscopy; Lung biopsy; Intervention guiding; Airway codification
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Carles Sanchez, Miguel Viñas, Coen Antens, Agnes Borras, & Debora Gil. (2018). "Back to Front Architecture for Diagnosis as a Service " In 20th International Symposium on Symbolic and Numeric Algorithms for Scientific Computing (pp. 343–346).
Abstract: Software as a Service (SaaS) is a cloud computing model in which a provider hosts applications in a server that customers use via internet. Since SaaS does not require to install applications on customers' own computers, it allows the use by multiple users of highly specialized software without extra expenses for hardware acquisition or licensing. A SaaS tailored for clinical needs not only would alleviate licensing costs, but also would facilitate easy access to new methods for diagnosis assistance. This paper presents a SaaS client-server architecture for Diagnosis as a Service (DaaS). The server is based on docker technology in order to allow execution of softwares implemented in different languages with the highest portability and scalability. The client is a content management system allowing the design of websites with multimedia content and interactive visualization of results allowing user editing. We explain a usage case that uses our DaaS as crowdsourcing platform in a multicentric pilot study carried out to evaluate the clinical benefits of a software for assessment of central airway obstruction.
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Debora Gil, Agnes Borras, Sergio Vera, & Miguel Angel Gonzalez Ballester. (2013). "A Validation Benchmark for Assessment of Medial Surface Quality for Medical Applications " In 9th International Conference on Computer Vision Systems (Vol. 7963, pp. 334–343). Springer Berlin Heidelberg.
Abstract: Confident use of medial surfaces in medical decision support systems requires evaluating their quality for detecting pathological deformations and describing anatomical volumes. Validation in the medical imaging field is a challenging task mainly due to the difficulties for getting consensual ground truth. In this paper we propose a validation benchmark for assessing medial surfaces in the context of medical applications. Our benchmark includes a home-made database of synthetic medial surfaces and volumes and specific scores for evaluating surface accuracy, its stability against volume deformations and its capabilities for accurate reconstruction of anatomical volumes.
Keywords: Medial Surfaces; Shape Representation; Medical Applications; Performance Evaluation
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Debora Gil, Agnes Borras, Ruth Aris, Mariano Vazquez, Pierre Lafortune, & Guillame Houzeaux. (2012). "What a difference in biomechanics cardiac fiber makes " In Statistical Atlases And Computational Models Of The Heart: Imaging and Modelling Challenges (Vol. 7746, pp. 253–260). Springer Berlin Heidelberg.
Abstract: Computational simulations of the heart are a powerful tool for a comprehensive understanding of cardiac function and its intrinsic relationship with its muscular architecture. Cardiac biomechanical models require a vector field representing the orientation of cardiac fibers. A wrong orientation of the fibers can lead to a
non-realistic simulation of the heart functionality. In this paper we explore the impact of the fiber information on the simulated biomechanics of cardiac muscular anatomy. We have used the John Hopkins database to perform a biomechanical simulation using both a synthetic benchmark fiber distribution and the data obtained experimentally from DTI. Results illustrate how differences in fiber orientation affect heart deformation along cardiac cycle.
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