Abstract: Guided image processing techniques are widely used to extract meaningful information from a guiding image and facilitate the enhancement of the guided one. This paper specifically addresses the challenge of guided thermal image super-resolution, where a low-resolution thermal image is enhanced using a high-resolution visible spectrum image. We propose a new strategy that enhances outcomes from current guided super-resolution methods. This is achieved by transforming the initial guiding data into a representation resembling a thermal-like image, which is more closely in sync with the intended output. Experimental results with upscale factors of 8 and 16, demonstrate the outstanding performance of our approach in guided thermal image super-resolution obtained by mapping the original guiding information to a thermal-like image representation.

Abstract: Previous studies suggested that lateral interactions of V1 cells are responsible, among other visual effects, of bottom-up visual attention (alternatively named visual salience or saliency). Our objective is to mimic these connections with a neurodynamic network of firing-rate neurons in order to predict visual attention. Early visual subcortical processes (i.e. retinal and thalamic) are functionally simulated. An implementation of the cortical magnification function is included to define the retinotopical projections towards V1, processing neuronal activity for each distinct view during scene observation. Novel computational definitions of top-down inhibition (in terms of inhibition of return, oculomotor and selection mechanisms), are also proposed to predict attention in Free-Viewing and Visual Search tasks. Results show that our model outpeforms other biologically inspired models of saliency prediction while predicting visual saccade sequences with the same model. We also show how temporal and spatial characteristics of saccade amplitude and inhibition of return can improve prediction of saccades, as well as how distinct search strategies (in terms of feature-selective or category-specific inhibition) can predict attention at distinct image contexts.

Abstract: Background Reliable predictive imaging markers of response to immune checkpoint inhibitors are needed. Purpose To develop and validate a pretreatment CT-based radiomics signature to predict response to immune checkpoint inhibitors in advanced solid tumors. Materials and Methods In this retrospective study, a radiomics signature was developed in patients with advanced solid tumors (including breast, cervix, gastrointestinal) treated with anti-programmed cell death-1 or programmed cell death ligand-1 monotherapy from August 2012 to May 2018 (cohort 1). This was tested in patients with bladder and lung cancer (cohorts 2 and 3). Radiomics variables were extracted from all metastases delineated at pretreatment CT and selected by using an elastic-net model. A regression model combined radiomics and clinical variables with response as the end point. Biologic validation of the radiomics score with RNA profiling of cytotoxic cells (cohort 4) was assessed with Mann-Whitney analysis. Results The radiomics signature was developed in 85 patients (cohort 1: mean age, 58 years ± 13 [standard deviation]; 43 men) and tested on 46 patients (cohort 2: mean age, 70 years ± 12; 37 men) and 47 patients (cohort 3: mean age, 64 years ± 11; 40 men). Biologic validation was performed in a further cohort of 20 patients (cohort 4: mean age, 60 years ± 13; 14 men). The radiomics signature was associated with clinical response to immune checkpoint inhibitors (area under the curve [AUC], 0.70; 95% CI: 0.64, 0.77; P < .001). In cohorts 2 and 3, the AUC was 0.67 (95% CI: 0.58, 0.76) and 0.67 (95% CI: 0.56, 0.77; P < .001), respectively. A radiomics-clinical signature (including baseline albumin level and lymphocyte count) improved on radiomics-only performance (AUC, 0.74 [95% CI: 0.63, 0.84; P < .001]; Akaike information criterion, 107.00 and 109.90, respectively). Conclusion A pretreatment CT-based radiomics signature is associated with response to immune checkpoint inhibitors, likely reflecting the tumor immunophenotype. © RSNA, 2021 Online supplemental material is available for this article. See also the editorial by Summers in this issue.

Abstract: We describe an equivalence of categories between the category of mixed Hodge structures and a category of equivariant vector bundles on a toric model of the complex projective plane which verify some semistability condition. We then apply this correspondence to define an invariant which generalizes the notion of R-split mixed Hodge structure and give calculations for the first group of cohomology of possibly non smooth or non-complete curves of genus 0 and 1. Finally, we describe some extension groups of mixed Hodge structures in terms of equivariant extensions of coherent sheaves. © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim

Abstract: Rain removal plays an important role in the restoration of degraded images. Recently, CNN-based methods have achieved remarkable success. However, these approaches neglect that the appearance of real-world rain is often accompanied by low light conditions, which will further degrade the image quality, thereby hindering the restoration mission. Therefore, it is very indispensable to jointly remove the rain and enhance illumination for real-world rain image restoration. To this end, we proposed a novel spatially-adaptive network, dubbed SANet, which can remove the rain and enhance illumination in one go with the guidance of degradation mask. Meanwhile, to fully utilize negative samples, a contrastive loss is proposed to preserve more natural textures and consistent illumination. In addition, we present a new synthetic dataset, named DarkRain, to boost the development of rain image restoration algorithms in practical scenarios. DarkRain not only contains different degrees of rain, but also considers different lighting conditions, and more realistically simulates real-world rainfall scenarios. SANet is extensively evaluated on the proposed dataset and attains new state-of-the-art performance against other combining methods. Moreover, after a simple transformation, our SANet surpasses existing the state-of-the-art algorithms in both rain removal and low-light image enhancement.

Abstract: We address the source-free domain adaptation (SFDA) problem, where only the source model is available during adaptation to the target domain. We consider two settings: the offline setting where all target data can be visited multiple times (epochs) to arrive at a prediction for each target sample, and the online setting where the target data needs to be directly classified upon arrival. Inspired by diverse classifier based domain adaptation methods, in this paper we introduce a second classifier, but with another classifier head fixed. When adapting to the target domain, the additional classifier initialized from source classifier is expected to find misclassified features. Next, when updating the feature extractor, those features will be pushed towards the right side of the source decision boundary, thus achieving source-free domain adaptation. Experimental results show that the proposed method achieves competitive results for offline SFDA on several benchmark datasets compared with existing DA and SFDA methods, and our method surpasses by a large margin other SFDA methods under online source-free domain adaptation setting.