Abstract: International benchmarking competitions have become fundamental for the comparative performance assessment of image analysis methods. However, little attention has been given to investigating what can be learnt from these competitions. Do they really generate scientific progress? What are common and successful participation strategies? What makes a solution superior to a competing method? To address this gap in the literature, we performed a multi-center study with all 80 competitions that were conducted in the scope of IEEE ISBI 2021 and MICCAI 2021. Statistical analyses performed based on comprehensive descriptions of the submitted algorithms linked to their rank as well as the underlying participation strategies revealed common characteristics of winning solutions. These typically include the use of multi-task learning (63%) and/or multi-stage pipelines (61%), and a focus on augmentation (100%), image preprocessing (97%), data curation (79%), and postprocessing (66%). The “typical” lead of a winning team is a computer scientist with a doctoral degree, five years of experience in biomedical image analysis, and four years of experience in deep learning. Two core general development strategies stood out for highly-ranked teams: the reflection of the metrics in the method design and the focus on analyzing and handling failure cases. According to the organizers, 43% of the winning algorithms exceeded the state of the art but only 11% completely solved the respective domain problem. The insights of our study could help researchers (1) improve algorithm development strategies when approaching new problems, and (2) focus on open research questions revealed by this work.

Abstract: Deep neural networks represent a compelling technique to tackle complex real-world problems, but are over-parameterized and often suffer from over- or under-confident estimates. Deep ensembles have shown better parameter estimations and often provide reliable uncertainty estimates that contribute to the robustness of the results. In this work, we propose a new metric to identify samples that are hard to classify. Our metric is defined as coincidence score for deep ensembles which measures the agreement of its individual models. The main hypothesis we rely on is that deep learning algorithms learn the low-loss samples better compared to large-loss samples. In order to compensate for this, we use controlled over-sampling on the identified ”hard” samples using proper data augmentation schemes to enable the models to learn those samples better. We validate the proposed metric using two public food datasets on different backbone architectures and show the improvements compared to the conventional deep neural network training using different performance metrics.

Abstract: We consider a quantum system that is being continuously monitored, giving rise to a measurement signal. From such a stream of data, information needs to be inferred about the underlying system's dynamics. Here we focus on hypothesis testing problems and put forward the usage of sequential strategies where the signal is analyzed in real time, allowing the experiment to be concluded as soon as the underlying hypothesis can be identified with a certified prescribed success probability. We analyze the performance of sequential tests by studying the stopping-time behavior, showing a considerable advantage over currently-used strategies based on a fixed predetermined measurement time.

Abstract: This paper investigates the effectiveness of different deep learning HTR families, including LSTM, Seq2Seq, and transformer-based approaches with self-supervised pretraining, in recognizing ciphered manuscripts from different historical periods and cultures. The goal is to identify the most suitable method or training techniques for recognizing ciphered manuscripts and to provide insights into the challenges and opportunities in this field of research. We evaluate the performance of these models on several datasets of ciphered manuscripts and discuss their results. This study contributes to the development of more accurate and efficient methods for recognizing historical manuscripts for the preservation and dissemination of our cultural heritage.

Abstract: Self-supervised learning has recently emerged as a strong alternative in document analysis. These approaches are now capable of learning high-quality image representations and overcoming the limitations of supervised methods, which require a large amount of labeled data. However, these methods are unable to capture new knowledge in an incremental fashion, where data is presented to the model sequentially, which is closer to the realistic scenario. In this paper, we explore the potential of continual self-supervised learning to alleviate the catastrophic forgetting problem in handwritten text recognition, as an example of sequence recognition. Our method consists in adding intermediate layers called adapters for each task, and efficiently distilling knowledge from the previous model while learning the current task. Our proposed framework is efficient in both computation and memory complexity. To demonstrate its effectiveness, we evaluate our method by transferring the learned model to diverse text recognition downstream tasks, including Latin and non-Latin scripts. As far as we know, this is the first application of continual self-supervised learning for handwritten text recognition. We attain state-of-the-art performance on English, Italian and Russian scripts, whilst adding only a few parameters per task. The code and trained models will be publicly available.

Abstract: Multi-label zero-shot learning strives to classify images into multiple unseen categories for which no data is available during training. The test samples can additionally contain seen categories in the generalized variant. Existing approaches rely on learning either shared or label-specific attention from the seen classes. Nevertheless, computing reliable attention maps for unseen classes during inference in a multi-label setting is still a challenge. In contrast, state-of-the-art single-label generative adversarial network (GAN) based approaches learn to directly synthesize the class-specific visual features from the corresponding class attribute embeddings. However, synthesizing multi-label features from GANs is still unexplored in the context of zero-shot setting. When multiple objects occur jointly in a single image, a critical question is how to effectively fuse multi-class information. In this work, we introduce different fusion approaches at the attribute-level, feature-level and cross-level (across attribute and feature-levels) for synthesizing multi-label features from their corresponding multi-label class embeddings. To the best of our knowledge, our work is the first to tackle the problem of multi-label feature synthesis in the (generalized) zero-shot setting. Our cross-level fusion-based generative approach outperforms the state-of-the-art on three zero-shot benchmarks: NUS-WIDE, Open Images and MS COCO. Furthermore, we show the generalization capabilities of our fusion approach in the zero-shot detection task on MS COCO, achieving favorable performance against existing methods.

Abstract: This work addresses the detection of Helicobacter pylori a bacterium classified since 1994 as class 1 carcinogen to humans. By its highest specificity and sensitivity, the preferred diagnosis technique is the analysis of histological images with immunohistochemical staining, a process in which certain stained antibodies bind to antigens of the biological element of interest. This analysis is a time demanding task, which is currently done by an expert pathologist that visually inspects the digitized samples.
We propose to use autoencoders to learn latent patterns of healthy tissue and detect H. pylori as an anomaly in image staining. Unlike existing classification approaches, an autoencoder is able to learn patterns in an unsupervised manner (without the need of image annotations) with high performance. In particular, our model has an overall 91% of accuracy with 86\% sensitivity, 96% specificity and 0.97 AUC in the detection of H. pylori.

Abstract: Global visual localization estimates the absolute pose of a camera using a single image, in a previously mapped area. Obtaining the pose from a single image enables many robotics and augmented/virtual reality applications. Inspired by latest advances in deep learning, many existing approaches directly learn and regress 6 DoF pose from an input image. However, these methods do not fully utilize the underlying scene geometry for pose regression. The challenge in monocular relocalization is the minimal availability of supervised training data, which is just the corresponding 6 DoF poses of the images. In this letter, we propose to utilize these minimal available labels (i.e., poses) to learn the underlying 3D geometry of the scene and use the geometry to estimate the 6 DoF camera pose. We present a learning method that uses these pose labels and rigid alignment to learn two 3D geometric representations ( X, Y, Z coordinates ) of the scene, one in camera coordinate frame and the other in global coordinate frame. Given a single image, it estimates these two 3D scene representations, which are then aligned to estimate a pose that matches the pose label. This formulation allows for the active inclusion of additional learning constraints to minimize 3D alignment errors between the two 3D scene representations, and 2D re-projection errors between the 3D global scene representation and 2D image pixels, resulting in improved localization accuracy. During inference, our model estimates the 3D scene geometry in camera and global frames and aligns them rigidly to obtain pose in real-time. We evaluate our work on three common visual localization datasets, conduct ablation studies, and show that our method exceeds state-of-the-art regression methods' pose accuracy on all datasets.