Abstract: In the early twenty first century Given Imaging Ltd. presented wireless capsule endoscopy (WCE) as a new technological breakthrough that allowed the visualization of
the intestine by using a small, swallowed camera. This small size device was received
with a high enthusiasm within the medical community, and until now, it is still one
of the medical devices with the highest use growth rate. WCE can be used as a novel
diagnostic tool that presents several clinical advantages, since it is non-invasive and
at the same time it provides, for the first time, a full picture of the small bowel morphology, contents and dynamics. Since its appearance, the WCE has been used to
detect several intestinal dysfunctions such as: polyps, ulcers and bleeding. However,
the visual analysis of WCE videos presents an important drawback: the long time
required by the physicians for proper video visualization. In this sense and regarding
to this limitation, the development of computer aided systems is required for the extensive use of WCE in the medical community.
The work presented in this thesis is a set of contributions for the automatic image
analysis and computer-aided diagnosis of intestinal motility disorders using WCE.
Until now, the diagnosis of small bowel motility dysfunctions was basically performed
by invasive techniques such as the manometry test, which can only be conducted at
some referral centers around the world owing to the complexity of the procedure and
the medial expertise required in the interpretation of the results.
Our contributions are divided in three main blocks:
1. Image analysis by computer vision techniques to detect events in the endoluminal WCE scene. Several methods have been proposed to detect visual events
such as: intestinal contractions, intestinal content, tunnel and wrinkles;
2. Machine learning techniques for the analysis and the manipulation of the data
from WCE. These methods have been proposed in order to overcome the problems that the analysis of WCE presents such as: video acquisition cost, unlabeled data and large number of data;
3. Two different systems for the computer-aided diagnosis of intestinal motility
disorders using WCE. The first system presents a fully automatic method that
aids at discriminating healthy subjects from patients with severe intestinal motor disorders like pseudo-obstruction or food intolerance. The second system presents another automatic method that models healthy subjects and discriminate them from mild intestinal motility patients.

Abstract: Put succinctly, the bag-of-words based image representation is the most successful approach for object and scene recognition. Within the bag-of-words framework the optimal fusion of multiple cues, such as shape, texture and color, still remains an active research domain. There exist two main approaches to combine color and shape information within the bag-of-words framework. The first approach called, early fusion, fuses color and shape at the feature level as a result of which a joint colorshape vocabulary is produced. The second approach, called late fusion, concatenates histogram representation of both color and shape, obtained independently. In the first part of this thesis, we analyze the theoretical implications of both early and late feature fusion. We demonstrate that both these approaches are suboptimal for a subset of object categories. Consequently, we propose a novel method for recognizing object categories when using multiple cues by separately processing the shape and color cues and combining them by modulating the shape features by category specific color attention. Color is used to compute bottom-up and top-down attention maps. Subsequently, the color attention maps are used to modulate the weights of the shape features. Shape features are given more weight in regions with higher attention and vice versa. The approach is tested on several benchmark object recognition data sets and the results clearly demonstrate the effectiveness of our proposed method. In the second part of the thesis, we investigate the problem of obtaining compact spatial pyramid representations for object and scene recognition. Spatial pyramids have been successfully applied to incorporate spatial information into bag-of-words based image representation. However, a major drawback of spatial pyramids is that it leads to high dimensional image representations. We present a novel framework for obtaining compact pyramid representation. The approach reduces the size of a high dimensional pyramid representation upto an order of magnitude without any significant reduction in accuracy. Moreover, we also investigate the optimal combination of multiple features such as color and shape within the context of our compact pyramid representation. Finally, we describe a novel technique to build discriminative visual words from multiple cues learned independently from training images. To this end, we use an information theoretic vocabulary compression technique to find discriminative combinations of visual cues and the resulting visual vocabulary is compact, has the cue binding property, and supports individual weighting of cues in the final image representation. The approach is tested on standard object recognition data sets. The results obtained clearly demonstrate the effectiveness of our approach.

Abstract: Pedestrian Protection Systems (PPSs) are on-board systems aimed at detecting and tracking people in the surroundings of a vehicle in order to avoid potentially dangerous situations. These systems, together with other Advanced Driver Assistance Systems (ADAS) such as lane departure warning or adaptive cruise control, are one of the most promising ways to improve traffic safety. By the use of computer vision, cameras working either in the visible or infra-red spectra have been demonstrated as a reliable sensor to perform this task. Nevertheless, the variability of human’s appearance, not only in terms of clothing and sizes but also as a result of their dynamic shape, makes pedestrians one of the most complex classes even for computer vision. Moreover, the unstructured changing and unpredictable environment in which such on-board systems must work makes detection a difficult task to be carried out with the demanded robustness. In this brief, the state of the art in PPSs is introduced through the review of the most relevant papers of the last decade. A common computational architecture is presented as a framework to organize each method according to its main contribution. More than 300 papers are referenced, most of them addressing pedestrian detection and others corresponding to the descriptors (features), pedestrian models, and learning machines used. In addition, an overview of topics such as real-time aspects, systems benchmarking and future challenges of this research area are presented.

Abstract: During the last decade vision-based human detection systems have started to play a key rolein multiple applications linked to driver assistance, surveillance, robot sensing and home automation.
Detecting humans is by far one of the most challenging tasks in Computer Vision.
This is mainly due to the high degree of variability in the human appearanceassociated to
the clothing, pose, shape and size. Besides, other factors such as cluttered scenarios, partial occlusions, or environmental conditions can make the detection task even harder.
Most promising methods of the state-of-the-art rely on discriminative learning paradigms which are fed with positive and negative examples. The training data is one of the most
relevant elements in order to build a robust detector as it has to cope the large variability of the target. In order to create this dataset human supervision is required. The drawback at this point is the arduous effort of annotating as well as looking for such claimed variability.
In this PhD thesis we address two recurrent problems in the literature. In the first stage,we aim to reduce the consuming task of annotating, namely, by using computer graphics.
More concretely, we develop a virtual urban scenario for later generating a pedestrian dataset.
Then, we train a detector using this dataset, and finally we assess if this detector can be successfully applied in a real scenario.
In the second stage, we focus on increasing the robustness of our pedestrian detectors
under partial occlusions. In particular, we present a novel occlusion handling approach to increase the performance of block-based holistic methods under partial occlusions. For this purpose, we make use of local experts via a RandomSubspaceMethod (RSM) to handle these cases. If the method infers a possible partial occlusion, then the RSM, based on performance statistics obtained from partially occluded data, is applied. The last objective of this thesis
is to propose a robust pedestrian detector based on an ensemble of local experts. To achieve this goal, we use the random forest paradigm, where the trees act as ensembles an their nodesare the local experts. In particular, each expert focus on performing a robust classification ofa pedestrian body patch. This approach offers computational efficiency and far less design complexity when compared to other state-of-the-artmethods, while reaching better accuracy

Abstract: Humans can effortlessly perceive faces, follow them over space and time, and decode their rich content, such as pose, identity and expression. However, despite many decades of research on automatic facial perception in areas like face detection, expression recognition, pose estimation and face recognition, and despite many successes, a complete solution remains elusive. This thesis is dedicated to three problems in automatic face perception, namely face detection, face tracking and pose estimation.
In face detection, an initial simple model is presented that uses pixel-based heuristics to segment skin locations and hand-crafted rules to determine the locations of the faces present in an image. Different colorspaces are studied to judge whether a colorspace transformation can aid skin color detection. The output of this study is used in the design of a more complex face detector that is able to successfully generalize to different scenarios.
In face tracking, a framework that combines estimation and control in a joint scheme is presented to track a face with a single pan-tilt-zoom camera. While this work is mainly motivated by tracking faces, it can be easily applied atop of any detector to track different objects. The applicability of this method is demonstrated on simulated as well as real-life scenarios.
The last and most important part of this thesis is dedicate to monocular head pose estimation. In this part, a method based on partial least squares (PLS) regression is proposed to estimate pose and solve the alignment problem simultaneously. The contributions of this work are two-fold: 1) demonstrating that the proposed method achieves better than state-of-the-art results on the estimation problem and 2) developing a technique to reduce misalignment based on the learned PLS factors that outperform multiple instance learning (MIL) without the need for any re-training or the inclusion of misaligned samples in the training process, as normally done in MIL.

Abstract: Pedestrian detection is of paramount interest for many applications, e.g. Advanced Driver Assistance Systems, Intelligent Video Surveillance and Multimedia systems. Most promising pedestrian detectors rely on appearance-based classifiers trained with annotated data. However, the required annotation step represents an intensive and subjective task for humans, what makes worth to minimize their intervention in this process by using computational tools like realistic virtual worlds. The reason to use these kind of tools relies in the fact that they allow the automatic generation of precise and rich annotations of visual information. Nevertheless, the use of this kind of data comes with the following question: can a pedestrian appearance model learnt with virtual-world data work successfully for pedestrian detection in real-world scenarios?. To answer this question, we conduct different experiments that suggest a positive answer. However, the pedestrian classifiers trained with virtual-world data can suffer the so called dataset shift problem as real-world based classifiers does. Accordingly, we have designed different domain adaptation techniques to face this problem, all of them integrated in a same framework (V-AYLA). We have explored different methods to train a domain adapted pedestrian classifiers by collecting a few pedestrian samples from the target domain (real world) and combining them with many samples of the source domain (virtual world). The extensive experiments we present show that pedestrian detectors developed within the V-AYLA framework do achieve domain adaptation. Ideally, we would like to adapt our system without any human intervention. Therefore, as a first proof of concept we also propose an unsupervised domain adaptation technique that avoids human intervention during the adaptation process. To the best of our knowledge, this Thesis work is the first demonstrating adaptation of virtual and real worlds for developing an object detector. Last but not least, we also assessed a different strategy to avoid the dataset shift that consists in collecting real-world samples and retrain with them in such a way that no bounding boxes of real-world pedestrians have to be provided. We show that the generated classifier is competitive with respect to the counterpart trained with samples collected by manually annotating pedestrian bounding boxes. The results presented on this Thesis not only end with a proposal for adapting a virtual-world pedestrian detector to the real world, but also it goes further by pointing out a new methodology that would allow the system to adapt to different situations, which we hope will provide the foundations for future research in this unexplored area.