Abstract: This paper presents a supervised subspace learning method called Kernel Generalized Discriminative Common Vectors (KGDCV), as a novel extension of the known Discriminative Common Vectors method with Kernels. Our method combines the advantages of kernel methods to model complex data and solve nonlinear
problems with moderate computational complexity, with the better generalization properties of generalized approaches for large dimensional data. These attractive combination makes KGDCV specially suited for feature extraction and classification in computer vision, image processing and pattern recognition applications. Two different approaches to this generalization are proposed, a first one based on the kernel trick (KT) and a second one based on the nonlinear projection trick (NPT) for even higher efficiency. Both methodologies
have been validated on four different image datasets containing faces, objects and handwritten digits, and compared against well known non-linear state-of-art methods. Results show better discriminant properties than other generalized approaches both linear or kernel. In addition, the KGDCV-NPT approach presents a considerable computational gain, without compromising the accuracy of the model.

Abstract: Background:
Suicide risk assessment usually involves an interaction between doctors and patients. However, a significant number of people with mental disorders receive no treatment for their condition due to the limited access to mental health care facilities; the reduced availability of clinicians; the lack of awareness; and stigma, neglect, and discrimination surrounding mental disorders. In contrast, internet access and social media usage have increased significantly, providing experts and patients with a means of communication that may contribute to the development of methods to detect mental health issues among social media users.
Objective:
This paper aimed to describe an approach for the suicide risk assessment of Spanish-speaking users on social media. We aimed to explore behavioral, relational, and multimodal data extracted from multiple social platforms and develop machine learning models to detect users at risk.
Methods:
We characterized users based on their writings, posting patterns, relations with other users, and images posted. We also evaluated statistical and deep learning approaches to handle multimodal data for the detection of users with signs of suicidal ideation (suicidal ideation risk group). Our methods were evaluated over a dataset of 252 users annotated by clinicians. To evaluate the performance of our models, we distinguished 2 control groups: users who make use of suicide-related vocabulary (focused control group) and generic random users (generic control group).
Results:
We identified significant statistical differences between the textual and behavioral attributes of each of the control groups compared with the suicidal ideation risk group. At a 95% CI, when comparing the suicidal ideation risk group and the focused control group, the number of friends (P=.04) and median tweet length (P=.04) were significantly different. The median number of friends for a focused control user (median 578.5) was higher than that for a user at risk (median 372.0). Similarly, the median tweet length was higher for focused control users, with 16 words against 13 words of suicidal ideation risk users. Our findings also show that the combination of textual, visual, relational, and behavioral data outperforms the accuracy of using each modality separately. We defined text-based baseline models based on bag of words and word embeddings, which were outperformed by our models, obtaining an increase in accuracy of up to 8% when distinguishing users at risk from both types of control users.
Conclusions:
The types of attributes analyzed are significant for detecting users at risk, and their combination outperforms the results provided by generic, exclusively text-based baseline models. After evaluating the contribution of image-based predictive models, we believe that our results can be improved by enhancing the models based on textual and relational features. These methods can be extended and applied to different use cases related to other mental disorders.

Abstract: Whole-body 3D PET/CT tumoral volume segmentation provides relevant diagnostic and prognostic information in clinical oncology and nuclear medicine. Carrying out this procedure manually by a medical expert is time consuming and suffers from inter- and intra-observer variabilities. In this paper, a completely automatic approach to this task is presented. First, the problem is stated and described both in clinical and technological terms. Then, a novel supervised learning segmentation framework is introduced. The segmentation by learning approach is defined within a Cascade of Adaboost classifiers and a 3D contextual proposal of Multiscale Stacked Sequential Learning. Segmentation accuracy results on 200 Breast Cancer whole body PET/CT volumes show mean 49% sensitivity, 99.993% specificity and 39% Jaccard overlap Index, which represent good performance results both at the clinical and technological level.

Abstract: INTRODUCTION:
Sleep surfaces must adapt to individual somatotypic features to maintain a comfortable, convenient and healthy sleep, preventing diseases and injuries. Individually determining the most adequate rest surface can often be a complex and subjective question.
OBJECTIVES:
To design and validate an automatic multimodal somatotype determination model to automatically recommend an individually designed mattress-topper-pillow combination.
METHODS:
Design and validation of an automated prescription model for an individualised sleep system is performed through a single-image 2 D-3 D analysis and body pressure distribution, to objectively determine optimal individual sleep surfaces combining five different mattress densities, three different toppers and three cervical pillows.
RESULTS:
A final study (n = 151) and re-analysis (n = 117) defined and validated the model, showing high correlations between calculated and real data (>85% in height and body circumferences, 89.9% in weight, 80.4% in body mass index and more than 70% in morphotype categorisation).
CONCLUSIONS:
Somatotype determination model can accurately prescribe an individualised sleep solution. This can be useful for healthy people and for health centres that need to adapt sleep surfaces to people with special needs. Next steps will increase model's accuracy and analise, if this prescribed individualised sleep solution can improve sleep quantity and quality; additionally, future studies will adapt the model to mattresses with technological improvements, tailor-made production and will define interfaces for people with special needs.

Abstract: Biologically inspired homing methods, such as the Average Landmark Vector, are an interesting solution for local navigation due to its simplicity. However, usually they require a modification of the environment by placing artificial landmarks in order to work reliably. In this paper we combine the Average Landmark Vector with invariant feature points automatically detected in panoramic images to overcome this limitation. The proposed approach has been evaluated first in simulation and, as promising results are found, also in two data sets of panoramas from real world environments.

Abstract: Colorectal cancer (CRC) is the third cause of cancer death world-wide. Currently, the standard approach to reduce CRC-related mortality is to perform regular screening in search for polyps and colonoscopy is the screening tool of choice. The main limitations of this screening procedure are polyp miss- rate and inability to perform visual assessment of polyp malignancy. These drawbacks can be reduced by designing Decision Support Systems (DSS) aim- ing to help clinicians in the different stages of the procedure by providing endoluminal scene segmentation. Thus, in this paper, we introduce an extended benchmark of colonoscopy image segmentation, with the hope of establishing a new strong benchmark for colonoscopy image analysis research. The proposed dataset consists of 4 relevant classes to inspect the endolumninal scene, tar- geting different clinical needs. Together with the dataset and taking advantage of advances in semantic segmentation literature, we provide new baselines by training standard fully convolutional networks (FCN). We perform a compar- ative study to show that FCN significantly outperform, without any further post-processing, prior results in endoluminal scene segmentation, especially with respect to polyp segmentation and localization.

Abstract: Otolith end organs of vertebrates sense linear accelerations of the head and gravitation. The hair cells on their epithelia are responsible for transduction. In mammals, the striola, parallel to the line where hair cells reverse their polarization, is a narrow region centered on a curve with curvature and torsion. It has been shown that the striolar region is functionally different from the rest, being involved in a phasic vestibular pathway. We propose a mathematical and computational model that explains the necessity of this amazing geometry for the striola to be able to carry out its function. Our hypothesis, related to the biophysics of the hair cells and to the physiology of their afferent neurons, is that striolar afferents collect information from several type I hair cells to detect the jerk in a large domain of acceleration directions. This predicts a mean number of two calyces for afferent neurons, as measured in rodents. The domain of acceleration directions sensed by our striolar model is compatible with the experimental results obtained on monkeys considering all afferents. Therefore, the main result of our study is that phasic and tonic vestibular afferents cover the same geometrical fields, but at different dynamical and frequency domains.