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Author Mireia Sole; Joan Blanco; Debora Gil; Oliver Valero; B. Cardenas; G. Fonseka; E. Anton; Alvaro Pascual; Richard Frodsham; Zaida Sarrate edit  doi
openurl 
  Title Time to match; when do homologous chromosomes become closer? Type Journal Article
  Year 2022 Publication Chromosoma Abbreviated Journal CHRO  
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  Abstract In most eukaryotes, pairing of homologous chromosomes is an essential feature of meiosis that ensures homologous recombination and segregation. However, when the pairing process begins, it is still under investigation. Contrasting data exists in Mus musculus, since both leptotene DSB-dependent and preleptotene DSB-independent mechanisms have been described. To unravel this contention, we examined homologous pairing in pre-meiotic and meiotic Mus musculus cells using a threedimensional fuorescence in situ hybridization-based protocol, which enables the analysis of the entire karyotype using DNA painting probes. Our data establishes in an unambiguously manner that 73.83% of homologous chromosomes are already paired at premeiotic stages (spermatogonia-early preleptotene spermatocytes). The percentage of paired homologous chromosomes increases to 84.60% at mid-preleptotene-zygotene stage, reaching 100% at pachytene stage. Importantly, our results demonstrate a high percentage of homologous pairing observed before the onset of meiosis; this pairing does not occur randomly, as the percentage was higher than that observed in somatic cells (19.47%) and between nonhomologous chromosomes (41.1%). Finally, we have also observed that premeiotic homologous pairing is asynchronous and independent of the chromosome size, GC content, or presence of NOR regions.  
  Address August, 2022  
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  Notes (up) IAM; 601.139; 600.145; 600.096 Approved no  
  Call Number Admin @ si @ SBG2022 Serial 3719  
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Author Sergio Vera; Debora Gil; Agnes Borras; Marius George Linguraru; Miguel Angel Gonzalez Ballester edit   pdf
url  doi
openurl 
  Title Geometric Steerable Medial Maps Type Journal Article
  Year 2013 Publication Machine Vision and Applications Abbreviated Journal MVA  
  Volume 24 Issue 6 Pages 1255-1266  
  Keywords Medial Representations ,Medial Manifolds Comparation , Surface , Reconstruction  
  Abstract In order to provide more intuitive and easily interpretable representations of complex shapes/organs, medial manifolds should reach a compromise between simplicity in geometry and capability for restoring the anatomy/shape of the organ/volume. Existing morphological methods show excellent results when applied to 2D objects, but their quality drops across dimensions.
This paper contributes to the computation of medial manifolds in two aspects. First, we provide a standard scheme for the computation of medial manifolds that avoids degenerated medial axis segments. Second, we introduce a continuous operator for accurate and efficient computation of medial structures of arbitrary dimension. We evaluate quantitatively the performance of our method with respect to existing approaches, by applying them to syn- thetic shapes of known medial geometry. We also show its higher performance for medical imaging applications in terms of simplicity of medial structures and capability for reconstructing the anatomical volume.
 
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  Publisher Springer Berlin Heidelberg Place of Publication Editor Mubarak Shah  
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  ISSN 0932-8092 ISBN Medium  
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  Notes (up) IAM; 605.203; 600.060; 600.044 Approved no  
  Call Number IAM @ iam @ VGB2013 Serial 2192  
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Author Debora Gil; Aura Hernandez-Sabate; Mireia Brunat;Steven Jansen; Jordi Martinez-Vilalta edit   pdf
doi  openurl
  Title Structure-preserving smoothing of biomedical images Type Journal Article
  Year 2011 Publication Pattern Recognition Abbreviated Journal PR  
  Volume 44 Issue 9 Pages 1842-1851  
  Keywords Non-linear smoothing; Differential geometry; Anatomical structures; segmentation; Cardiac magnetic resonance; Computerized tomography  
  Abstract Smoothing of biomedical images should preserve gray-level transitions between adjacent tissues, while restoring contours consistent with anatomical structures. Anisotropic diffusion operators are based on image appearance discontinuities (either local or contextual) and might fail at weak inter-tissue transitions. Meanwhile, the output of block-wise and morphological operations is prone to present a block structure due to the shape and size of the considered pixel neighborhood. In this contribution, we use differential geometry concepts to define a diffusion operator that restricts to image consistent level-sets. In this manner, the final state is a non-uniform intensity image presenting homogeneous inter-tissue transitions along anatomical structures, while smoothing intra-structure texture. Experiments on different types of medical images (magnetic resonance, computerized tomography) illustrate its benefit on a further process (such as segmentation) of images.  
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  ISSN 0031-3203 ISBN Medium  
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  Notes (up) IAM; ADAS Approved no  
  Call Number IAM @ iam @ GHB2011 Serial 1526  
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Author Enric Marti; J.Roncaries; Debora Gil; Aura Hernandez-Sabate; Antoni Gurgui; Ferran Poveda edit  doi
openurl 
  Title PBL On Line: A proposal for the organization, part-time monitoring and assessment of PBL group activities Type Journal
  Year 2015 Publication Journal of Technology and Science Education Abbreviated Journal JOTSE  
  Volume 5 Issue 2 Pages 87-96  
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  Notes (up) IAM; ADAS; 600.076; 600.075 Approved no  
  Call Number Admin @ si @ MRG2015 Serial 2608  
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Author Aura Hernandez-Sabate; Jose Elias Yauri; Pau Folch; Miquel Angel Piera; Debora Gil edit  doi
openurl 
  Title Recognition of the Mental Workloads of Pilots in the Cockpit Using EEG Signals Type Journal Article
  Year 2022 Publication Applied Sciences Abbreviated Journal APPLSCI  
  Volume 12 Issue 5 Pages 2298  
  Keywords Cognitive states; Mental workload; EEG analysis; Neural networks; Multimodal data fusion  
  Abstract The commercial flightdeck is a naturally multi-tasking work environment, one in which interruptions are frequent come in various forms, contributing in many cases to aviation incident reports. Automatic characterization of pilots’ workloads is essential to preventing these kind of incidents. In addition, minimizing the physiological sensor network as much as possible remains both a challenge and a requirement. Electroencephalogram (EEG) signals have shown high correlations with specific cognitive and mental states, such as workload. However, there is not enough evidence in the literature to validate how well models generalize in cases of new subjects performing tasks with workloads similar to the ones included during the model’s training. In this paper, we propose a convolutional neural network to classify EEG features across different mental workloads in a continuous performance task test that partly measures working memory and working memory capacity. Our model is valid at the general population level and it is able to transfer task learning to pilot mental workload recognition in a simulated operational environment.  
  Address February 2022  
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  Notes (up) IAM; ADAS; 600.139; 600.145; 600.118 Approved no  
  Call Number Admin @ si @ HYF2022 Serial 3720  
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