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Frederic Sampedro; Anna Domenech; Sergio Escalera; Ignasi Carrio |
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Title |
Deriving global quantitative tumor response parameters from 18F-FDG PET-CT scans in patients with non-Hodgkins lymphoma |
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Journal Article |
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Year |
2015 |
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Nuclear Medicine Communications |
Abbreviated Journal |
NMC |
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36 |
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4 |
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328-333 |
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OBJECTIVES:
The aim of the study was to address the need for quantifying the global cancer time evolution magnitude from a pair of time-consecutive positron emission tomography-computed tomography (PET-CT) scans. In particular, we focus on the computation of indicators using image-processing techniques that seek to model non-Hodgkin's lymphoma (NHL) progression or response severity.
MATERIALS AND METHODS:
A total of 89 pairs of time-consecutive PET-CT scans from NHL patients were stored in a nuclear medicine station for subsequent analysis. These were classified by a consensus of nuclear medicine physicians into progressions, partial responses, mixed responses, complete responses, and relapses. The cases of each group were ordered by magnitude following visual analysis. Thereafter, a set of quantitative indicators designed to model the cancer evolution magnitude within each group were computed using semiautomatic and automatic image-processing techniques. Performance evaluation of the proposed indicators was measured by a correlation analysis with the expert-based visual analysis.
RESULTS:
The set of proposed indicators achieved Pearson's correlation results in each group with respect to the expert-based visual analysis: 80.2% in progressions, 77.1% in partial response, 68.3% in mixed response, 88.5% in complete response, and 100% in relapse. In the progression and mixed response groups, the proposed indicators outperformed the common indicators used in clinical practice [changes in metabolic tumor volume, mean, maximum, peak standardized uptake value (SUV mean, SUV max, SUV peak), and total lesion glycolysis] by more than 40%.
CONCLUSION:
Computing global indicators of NHL response using PET-CT imaging techniques offers a strong correlation with the associated expert-based visual analysis, motivating the future incorporation of such quantitative and highly observer-independent indicators in oncological decision making or treatment response evaluation scenarios. |
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HuPBA;MILAB |
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Admin @ si @ SDE2015 |
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2605 |
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Author |
Jean-Pascal Jacob; Mariella Dimiccoli; Lionel Moisan |
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Title |
Active skeleton for bacteria modeling |
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Journal Article |
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2016 |
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Computer Methods in Biomechanics and Biomedical Engineering: Imaging and Visualization |
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CMBBE |
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5 |
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4 |
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274-286 |
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Bacteria modelling; medial axis; active contours; active skeleton; shape contraints |
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The investigation of spatio-temporal dynamics of bacterial cells and their molecular components requires automated image analysis tools to track cell shape properties and molecular component locations inside the cells. In the study of bacteria aging, the molecular components of interest are protein aggregates accumulated near bacteria boundaries. This particular location makes very ambiguous the correspondence between aggregates and cells, since computing accurately bacteria boundaries in phase-contrast time-lapse imaging is a challenging task. This paper proposes an active skeleton formulation for bacteria modeling which provides several advantages: an easy computation of shape properties (perimeter, length, thickness, orientation), an improved boundary accuracy in noisy images, and a natural bacteria-centered coordinate system that permits the intrinsic location of molecular components inside the cell. Starting from an initial skeleton estimate, the medial axis of the bacterium is obtained by minimizing an energy function which incorporates bacteria shape constraints. Experimental results on biological images and comparative evaluation of the performances validate the proposed approach for modeling cigar-shaped bacteria like Escherichia coli. The Image-J plugin of the proposed method can be found online at this http URL |
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MILAB |
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Admin @ si @ JDM2016 |
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2711 |
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Jean-Pascal Jacob; Mariella Dimiccoli; L. Moisan |
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Active skeleton for bacteria modelling |
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2017 |
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Computer Methods in Biomechanics and Biomedical Engineering: Imaging and Visualization |
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CMBBE |
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5 |
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4 |
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274-286 |
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The investigation of spatio-temporal dynamics of bacterial cells and their molecular components requires automated image analysis tools to track cell shape properties and molecular component locations inside the cells. In the study of bacteria aging, the molecular components of interest are protein aggregates accumulated near bacteria boundaries. This particular location makes very ambiguous the correspondence between aggregates and cells, since computing accurately bacteria boundaries in phase-contrast time-lapse imaging is a challenging task. This paper proposes an active skeleton formulation for bacteria modelling which provides several advantages: an easy computation of shape properties (perimeter, length, thickness and orientation), an improved boundary accuracy in noisy images and a natural bacteria-centred coordinate system that permits the intrinsic location of molecular components inside the cell. Starting from an initial skeleton estimate, the medial axis of the bacterium is obtained by minimising an energy function which incorporates bacteria shape constraints. Experimental results on biological images and comparative evaluation of the performances validate the proposed approach for modelling cigar-shaped bacteria like Escherichia coli. The Image-J plugin of the proposed method can be found online at http://fluobactracker.inrialpes.fr. |
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Taylor & Francis Group |
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MILAB; |
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Admin @ si @JDM2017 |
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2784 |
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Marc Oliu; Ciprian Corneanu; Kamal Nasrollahi; Olegs Nikisins; Sergio Escalera; Yunlian Sun; Haiqing Li; Zhenan Sun; Thomas B. Moeslund; Modris Greitans |
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Improved RGB-D-T based Face Recognition |
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Journal Article |
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2016 |
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IET Biometrics |
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BIO |
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5 |
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4 |
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297 - 303 |
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Reliable facial recognition systems are of crucial importance in various applications from entertainment to security. Thanks to the deep-learning concepts introduced in the field, a significant improvement in the performance of the unimodal facial recognition systems has been observed in the recent years. At the same time a multimodal facial recognition is a promising approach. This study combines the latest successes in both directions by applying deep learning convolutional neural networks (CNN) to the multimodal RGB, depth, and thermal (RGB-D-T) based facial recognition problem outperforming previously published results. Furthermore, a late fusion of the CNN-based recognition block with various hand-crafted features (local binary patterns, histograms of oriented gradients, Haar-like rectangular features, histograms of Gabor ordinal measures) is introduced, demonstrating even better recognition performance on a benchmark RGB-D-T database. The obtained results in this study show that the classical engineered features and CNN-based features can complement each other for recognition purposes. |
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HuPBA;MILAB; |
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Admin @ si @ OCN2016 |
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2854 |
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Author |
Alejandro Cartas; Juan Marin; Petia Radeva; Mariella Dimiccoli |
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Title |
Batch-based activity recognition from egocentric photo-streams revisited |
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Journal Article |
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Year |
2018 |
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Pattern Analysis and Applications |
Abbreviated Journal |
PAA |
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21 |
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4 |
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953–965 |
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Egocentric vision; Lifelogging; Activity recognition; Deep learning; Recurrent neural networks |
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Wearable cameras can gather large amounts of image data that provide rich visual information about the daily activities of the wearer. Motivated by the large number of health applications that could be enabled by the automatic recognition of daily activities, such as lifestyle characterization for habit improvement, context-aware personal assistance and tele-rehabilitation services, we propose a system to classify 21 daily activities from photo-streams acquired by a wearable photo-camera. Our approach combines the advantages of a late fusion ensemble strategy relying on convolutional neural networks at image level with the ability of recurrent neural networks to account for the temporal evolution of high-level features in photo-streams without relying on event boundaries. The proposed batch-based approach achieved an overall accuracy of 89.85%, outperforming state-of-the-art end-to-end methodologies. These results were achieved on a dataset consists of 44,902 egocentric pictures from three persons captured during 26 days in average. |
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MILAB; no proj |
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Admin @ si @ CMR2018 |
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3186 |
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