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Debora Gil, & Petia Radeva. (2004). Shape Restoration via a Regularized Curvature Flow. Journal of Mathematical Imaging and Vision, 21(3), 205–223.
Abstract: Any image filtering operator designed for automatic shape restoration should satisfy robustness (whatever the nature and degree of noise is) as well as non-trivial smooth asymptotic behavior. Moreover, a stopping criterion should be determined by characteristics of the evolved image rather than dependent on the number of iterations. Among the several PDE based techniques, curvature flows appear to be highly reliable for strongly noisy images compared to image diffusion processes.
In the present paper, we introduce a regularized curvature flow (RCF) that admits non-trivial steady states. It is based on a measure of the local curve smoothness that takes into account regularity of the curve curvature and serves as stopping term in the mean curvature flow. We prove that this measure decreases over the orbits of RCF, which endows the method with a natural stop criterion in terms of the magnitude of this measure. Further, in its discrete version it produces steady states consisting of piece-wise regular curves. Numerical experiments made on synthetic shapes corrupted with different kinds of noise show the abilities and limitations of each of the current geometric flows and the benefits of RCF. Finally, we present results on real images that illustrate the usefulness of the present approach in practical applications.
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Debora Gil, Oriol Rodriguez-Leor, Petia Radeva, & J. Mauri. (2008). Myocardial Perfusion Characterization From Contrast Angiography Spectral Distribution. IEEE Transactions on Medical Imaging, 27(5), 641–649.
Abstract: Despite recovering a normal coronary flow after acute myocardial infarction, percutaneous coronary intervention does not guarantee a proper perfusion (irrigation) of the infarcted area. This damage in microcirculation integrity may detrimentally affect the patient survival. Visual assessment of the myocardium opacification in contrast angiography serves to define a subjective score of the microcirculation integrity myocardial blush analysis (MBA). Although MBA correlates with patient prognosis its visual assessment is a very difficult task that requires of a highly expertise training in order to achieve a good intraobserver and interobserver agreement. In this paper, we provide objective descriptors of the myocardium staining pattern by analyzing the spectrum of the image local statistics. The descriptors proposed discriminate among the different phenomena observed in the angiographic sequence and allow defining an objective score of the myocardial perfusion.
Keywords: Contrast angiography; myocardial perfusion; spectral analysis.
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Debora Gil, Aura Hernandez-Sabate, Oriol Rodriguez, J. Mauri, & Petia Radeva. (2006). Statistical Strategy for Anisotropic Adventitia Modelling in IVUS. IEEE Transactions on Medical Imaging, 25(6), 768–778.
Abstract: Vessel plaque assessment by analysis of intravascular ultrasound sequences is a useful tool for cardiac disease diagnosis and intervention. Manual detection of luminal (inner) and mediaadventitia (external) vessel borders is the main activity of physicians in the process of lumen narrowing (plaque) quantification. Difficult definition of vessel border descriptors, as well as, shades, artifacts, and blurred signal response due to ultrasound physical properties trouble automated adventitia segmentation. In order to efficiently approach such a complex problem, we propose blending advanced anisotropic filtering operators and statistical classification techniques into a vessel border modelling strategy. Our systematic statistical analysis shows that the reported adventitia detection achieves an accuracy in the range of interobserver variability regardless of plaque nature, vessel geometry, and incomplete vessel borders. Index Terms–-Anisotropic processing, intravascular ultrasound (IVUS), vessel border segmentation, vessel structure classification.
Keywords: Corners; T-junctions; Wavelets
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David Rotger, Petia Radeva, & N. Bruining. (2010). Automatic Detection of Bioabsorbable Coronary Stents in IVUS Images using a Cascade of Classifiers. TITB - IEEE Transactions on Information Technology in Biomedicine, 14(2), 535 – 537.
Abstract: Bioabsorbable drug-eluting coronary stents present a very promising improvement to the common metallic ones solving some of the most important problems of stent implantation: the late restenosis. These stents made of poly-L-lactic acid cause a very subtle acoustic shadow (compared to the metallic ones) making difficult the automatic detection and measurements in images. In this paper, we propose a novel approach based on a cascade of GentleBoost classifiers to detect the stent struts using structural features to code the information of the different subregions of the struts. A stochastic gradient descent method is applied to optimize the overall performance of the detector. Validation results of struts detection are very encouraging with an average F-measure of 81%.
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David Rotger, Misael Rosales, Jaume Garcia, Oriol Pujol, J. Mauri, & Petia Radeva. (2003). Active Vessel: A New Multimedia Workstation for Intravascular Ultrasound and Angiography Fusion. Computers in Cardiology, 30, 65–68.
Abstract: AcriveVessel is a new multimedia workstation which enables the visualization, acquisition and handling of both image modalities, on- and ofline. It enables DICOM v3.0 decompression and browsing, video acquisition,repmduction and storage for IntraVascular UltraSound (IVUS) and angiograms with their corresponding ECG,automatic catheter segmentation in angiography images (using fast marching algorithm). BSpline models definition for vessel layers on IVUS images sequence and an extensively validated tool to fuse information. This approach defines the correspondence of every IVUS image with its correspondent point in the angiogram and viceversa. The 3 0 reconstruction of the NUS catheterhessel enables real distance measurements as well as threedimensional visualization showing vessel tortuosity in the space.
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