2011 |
|
|
Xavier Carrillo, E Fernandez-Nofrerias, Francesco Ciompi, O. Rodriguez-Leor, Petia Radeva, Neus Salvatella, et al. (2011). Changes in Radial Artery Volume Assessed Using Intravascular Ultrasound: A Comparison of Two Vasodilator Regimens in Transradial Coronary Intervention. JOIC - Journal of Invasive Cardiology, 23(10), 401–404.
Abstract: OBJECTIVES:
This study used intravascular ultrasound (IVUS) to evaluate radial artery volume changes after intraarterial administration of nitroglycerin and/or verapamil.
BACKGROUND:
Radial artery spasm, which is associated with radial artery size, is the main limitation of the transradial approach in percutaneous coronary interventions (PCI).
METHODS:
This prospective, randomized study compared the effect of two intra-arterial vasodilator regimens on radial artery volume: 0.2 mg of nitroglycerin plus 2.5 mg of verapamil (Group 1; n = 15) versus 2.5 mg of verapamil alone (Group 2; n = 15). Radial artery lumen volume was assessed using IVUS at two time points: at baseline (5 minutes after sheath insertion) and post-vasodilator (1 minute after drug administration). The luminal volume of the radial artery was computed using ECOC Random Fields (ECOC-RF), a technique used for automatic segmentation of luminal borders in longitudinal cut images from IVUS sequences.
RESULTS:
There was a significant increase in arterial lumen volume in both groups, with an increase from 451 ± 177 mm³ to 508 ± 192 mm³ (p = 0.001) in Group 1 and from 456 ± 188 mm³ to 509 ± 170 mm³ (p = 0.001) in Group 2. There were no significant differences between the groups in terms of absolute volume increase (58 mm³ versus 53 mm³, respectively; p = 0.65) or in relative volume increase (14% versus 20%, respectively; p = 0.69).
CONCLUSIONS:
Administration of nitroglycerin plus verapamil or verapamil alone to the radial artery resulted in similar increases in arterial lumen volume according to ECOC-RF IVUS measurements.
Keywords: radial; vasodilator treatment; percutaneous coronary intervention; IVUS; volumetric IVUS analysis
|
|
2010 |
|
|
Francesco Ciompi, Oriol Pujol, Carlo Gatta, O. Rodriguez-Leor, J. Mauri, & Petia Radeva. (2010). Fusing in-vitro and in-vivo intravascular ultrasound data for plaque characterization. IJCI - International Journal of Cardiovascular Imaging, 26(7), 763–779.
Abstract: Accurate detection of in-vivo vulnerable plaque in coronary arteries is still an open problem. Recent studies show that it is highly related to tissue structure and composition. Intravascular Ultrasound (IVUS) is a powerful imaging technique that gives a detailed cross-sectional image of the vessel, allowing to explore arteries morphology. IVUS data validation is usually performed by comparing post-mortem (in-vitro) IVUS data and corresponding histological analysis of the tissue. The main drawback of this method is the few number of available case studies and validated data due to the complex procedure of histological analysis of the tissue. On the other hand, IVUS data from in-vivo cases is easy to obtain but it can not be histologically validated. In this work, we propose to enhance the in-vitro training data set by selectively including examples from in-vivo plaques. For this purpose, a Sequential Floating Forward Selection method is reformulated in the context of plaque characterization. The enhanced classifier performance is validated on in-vitro data set, yielding an overall accuracy of 91.59% in discriminating among fibrotic, lipidic and calcified plaques, while reducing the gap between in-vivo and in-vitro data analysis. Experimental results suggest that the obtained classifier could be properly applied on in-vivo plaque characterization and also demonstrate that the common hypothesis of assuming the difference between in-vivo and in-vitro as negligible is incorrect.
|
|
|
|
Sergio Escalera, Oriol Pujol, & Petia Radeva. (2010). Error-Correcting Output Codes Library. JMLR - Journal of Machine Learning Research, 11, 661–664.
Abstract: (Feb):661−664
In this paper, we present an open source Error-Correcting Output Codes (ECOC) library. The ECOC framework is a powerful tool to deal with multi-class categorization problems. This library contains both state-of-the-art coding (one-versus-one, one-versus-all, dense random, sparse random, DECOC, forest-ECOC, and ECOC-ONE) and decoding designs (hamming, euclidean, inverse hamming, laplacian, β-density, attenuated, loss-based, probabilistic kernel-based, and loss-weighted) with the parameters defined by the authors, as well as the option to include your own coding, decoding, and base classifier.
|
|
|
|
Sergio Escalera, Oriol Pujol, & Petia Radeva. (2010). On the Decoding Process in Ternary Error-Correcting Output Codes. TPAMI - IEEE on Pattern Analysis and Machine Intelligence, 32(1), 120–134.
Abstract: A common way to model multiclass classification problems is to design a set of binary classifiers and to combine them. Error-correcting output codes (ECOC) represent a successful framework to deal with these type of problems. Recent works in the ECOC framework showed significant performance improvements by means of new problem-dependent designs based on the ternary ECOC framework. The ternary framework contains a larger set of binary problems because of the use of a ldquodo not carerdquo symbol that allows us to ignore some classes by a given classifier. However, there are no proper studies that analyze the effect of the new symbol at the decoding step. In this paper, we present a taxonomy that embeds all binary and ternary ECOC decoding strategies into four groups. We show that the zero symbol introduces two kinds of biases that require redefinition of the decoding design. A new type of decoding measure is proposed, and two novel decoding strategies are defined. We evaluate the state-of-the-art coding and decoding strategies over a set of UCI machine learning repository data sets and into a real traffic sign categorization problem. The experimental results show that, following the new decoding strategies, the performance of the ECOC design is significantly improved.
|
|
|
|
Sergio Escalera, Oriol Pujol, & Petia Radeva. (2010). Re-coding ECOCs without retraining. PRL - Pattern Recognition Letters, 31(7), 555–562.
Abstract: A standard way to deal with multi-class categorization problems is by the combination of binary classifiers in a pairwise voting procedure. Recently, this classical approach has been formalized in the Error-Correcting Output Codes (ECOC) framework. In the ECOC framework, the one-versus-one coding demonstrates to achieve higher performance than the rest of coding designs. The binary problems that we train in the one-versus-one strategy are significantly smaller than in the rest of designs, and usually easier to be learnt, taking into account the smaller overlapping between classes. However, a high percentage of the positions coded by zero of the coding matrix, which implies a high sparseness degree, does not codify meta-class membership information. In this paper, we show that using the training data we can redefine without re-training, in a problem-dependent way, the one-versus-one coding matrix so that the new coded information helps the system to increase its generalization capability. Moreover, the new re-coding strategy is generalized to be applied over any binary code. The results over several UCI Machine Learning repository data sets and two real multi-class problems show that performance improvements can be obtained re-coding the classical one-versus-one and Sparse random designs compared to different state-of-the-art ECOC configurations.
|
|
