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Frederic Sampedro, Anna Domenech, Sergio Escalera, & Ignasi Carrio. (2017). Computing quantitative indicators of structural renal damage in pediatric DMSA scans. REMNIM - Revista Española de Medicina Nuclear e Imagen Molecular, 36(2), 72–77.
Abstract: OBJECTIVES:
The proposal and implementation of a computational framework for the quantification of structural renal damage from 99mTc-dimercaptosuccinic acid (DMSA) scans. The aim of this work is to propose, implement, and validate a computational framework for the quantification of structural renal damage from DMSA scans and in an observer-independent manner.
MATERIALS AND METHODS:
From a set of 16 pediatric DMSA-positive scans and 16 matched controls and using both expert-guided and automatic approaches, a set of image-derived quantitative indicators was computed based on the relative size, intensity and histogram distribution of the lesion. A correlation analysis was conducted in order to investigate the association of these indicators with other clinical data of interest in this scenario, including C-reactive protein (CRP), white cell count, vesicoureteral reflux, fever, relative perfusion, and the presence of renal sequelae in a 6-month follow-up DMSA scan.
RESULTS:
A fully automatic lesion detection and segmentation system was able to successfully classify DMSA-positive from negative scans (AUC=0.92, sensitivity=81% and specificity=94%). The image-computed relative size of the lesion correlated with the presence of fever and CRP levels (p<0.05), and a measurement derived from the distribution histogram of the lesion obtained significant performance results in the detection of permanent renal damage (AUC=0.86, sensitivity=100% and specificity=75%).
CONCLUSIONS:
The proposal and implementation of a computational framework for the quantification of structural renal damage from DMSA scans showed a promising potential to complement visual diagnosis and non-imaging indicators.
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Simone Balocco, Carlo Gatta, Francesco Ciompi, A. Wahle, Petia Radeva, S. Carlier, et al. (2014). Standardized evaluation methodology and reference database for evaluating IVUS image segmentation. CMIG - Computerized Medical Imaging and Graphics, 38(2), 70–90.
Abstract: This paper describes an evaluation framework that allows a standardized and quantitative comparison of IVUS lumen and media segmentation algorithms. This framework has been introduced at the MICCAI 2011 Computing and Visualization for (Intra)Vascular Imaging (CVII) workshop, comparing the results of eight teams that participated.
We describe the available data-base comprising of multi-center, multi-vendor and multi-frequency IVUS datasets, their acquisition, the creation of the reference standard and the evaluation measures. The approaches address segmentation of the lumen, the media, or both borders; semi- or fully-automatic operation; and 2-D vs. 3-D methodology. Three performance measures for quantitative analysis have
been proposed. The results of the evaluation indicate that segmentation of the vessel lumen and media is possible with an accuracy that is comparable to manual annotation when semi-automatic methods are used, as well as encouraging results can be obtained also in case of fully-automatic segmentation. The analysis performed in this paper also highlights the challenges in IVUS segmentation that remains to be
solved.
Keywords: IVUS (intravascular ultrasound); Evaluation framework; Algorithm comparison; Image segmentation
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Pejman Rasti, Salma Samiei, Mary Agoyi, Sergio Escalera, & Gholamreza Anbarjafari. (2016). Robust non-blind color video watermarking using QR decomposition and entropy analysis. JVCIR - Journal of Visual Communication and Image Representation, 38, 838–847.
Abstract: Issues such as content identification, document and image security, audience measurement, ownership and copyright among others can be settled by the use of digital watermarking. Many recent video watermarking methods show drops in visual quality of the sequences. The present work addresses the aforementioned issue by introducing a robust and imperceptible non-blind color video frame watermarking algorithm. The method divides frames into moving and non-moving parts. The non-moving part of each color channel is processed separately using a block-based watermarking scheme. Blocks with an entropy lower than the average entropy of all blocks are subject to a further process for embedding the watermark image. Finally a watermarked frame is generated by adding moving parts to it. Several signal processing attacks are applied to each watermarked frame in order to perform experiments and are compared with some recent algorithms. Experimental results show that the proposed scheme is imperceptible and robust against common signal processing attacks.
Keywords: Video watermarking; QR decomposition; Discrete Wavelet Transformation; Chirp Z-transform; Singular value decomposition; Orthogonal–triangular decomposition
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Miguel Angel Bautista, Oriol Pujol, Fernando De la Torre, & Sergio Escalera. (2018). Error-Correcting Factorization. TPAMI - IEEE Transactions on Pattern Analysis and Machine Intelligence, 40, 2388–2401.
Abstract: Error Correcting Output Codes (ECOC) is a successful technique in multi-class classification, which is a core problem in Pattern Recognition and Machine Learning. A major advantage of ECOC over other methods is that the multi- class problem is decoupled into a set of binary problems that are solved independently. However, literature defines a general error-correcting capability for ECOCs without analyzing how it distributes among classes, hindering a deeper analysis of pair-wise error-correction. To address these limitations this paper proposes an Error-Correcting Factorization (ECF) method, our contribution is three fold: (I) We propose a novel representation of the error-correction capability, called the design matrix, that enables us to build an ECOC on the basis of allocating correction to pairs of classes. (II) We derive the optimal code length of an ECOC using rank properties of the design matrix. (III) ECF is formulated as a discrete optimization problem, and a relaxed solution is found using an efficient constrained block coordinate descent approach. (IV) Enabled by the flexibility introduced with the design matrix we propose to allocate the error-correction on classes that are prone to confusion. Experimental results in several databases show that when allocating the error-correction to confusable classes ECF outperforms state-of-the-art approaches.
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Hugo Bertiche, Meysam Madadi, & Sergio Escalera. (2021). PBNS: Physically Based Neural Simulation for Unsupervised Garment Pose Space Deformation. ACM Transactions on Graphics, 40(6), 1–14.
Abstract: We present a methodology to automatically obtain Pose Space Deformation (PSD) basis for rigged garments through deep learning. Classical approaches rely on Physically Based Simulations (PBS) to animate clothes. These are general solutions that, given a sufficiently fine-grained discretization of space and time, can achieve highly realistic results. However, they are computationally expensive and any scene modification prompts the need of re-simulation. Linear Blend Skinning (LBS) with PSD offers a lightweight alternative to PBS, though, it needs huge volumes of data to learn proper PSD. We propose using deep learning, formulated as an implicit PBS, to unsupervisedly learn realistic cloth Pose Space Deformations in a constrained scenario: dressed humans. Furthermore, we show it is possible to train these models in an amount of time comparable to a PBS of a few sequences. To the best of our knowledge, we are the first to propose a neural simulator for cloth.
While deep-based approaches in the domain are becoming a trend, these are data-hungry models. Moreover, authors often propose complex formulations to better learn wrinkles from PBS data. Supervised learning leads to physically inconsistent predictions that require collision solving to be used. Also, dependency on PBS data limits the scalability of these solutions, while their formulation hinders its applicability and compatibility. By proposing an unsupervised methodology to learn PSD for LBS models (3D animation standard), we overcome both of these drawbacks. Results obtained show cloth-consistency in the animated garments and meaningful pose-dependant folds and wrinkles. Our solution is extremely efficient, handles multiple layers of cloth, allows unsupervised outfit resizing and can be easily applied to any custom 3D avatar.
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