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Frederic Sampedro, Sergio Escalera, Anna Domenech, & Ignasi Carrio. (2015). Automatic Tumor Volume Segmentation in Whole-Body PET/CT Scans: A Supervised Learning Approach Source. JMIHI - Journal of Medical Imaging and Health Informatics, 5(2), 192–201.
Abstract: Whole-body 3D PET/CT tumoral volume segmentation provides relevant diagnostic and prognostic information in clinical oncology and nuclear medicine. Carrying out this procedure manually by a medical expert is time consuming and suffers from inter- and intra-observer variabilities. In this paper, a completely automatic approach to this task is presented. First, the problem is stated and described both in clinical and technological terms. Then, a novel supervised learning segmentation framework is introduced. The segmentation by learning approach is defined within a Cascade of Adaboost classifiers and a 3D contextual proposal of Multiscale Stacked Sequential Learning. Segmentation accuracy results on 200 Breast Cancer whole body PET/CT volumes show mean 49% sensitivity, 99.993% specificity and 39% Jaccard overlap Index, which represent good performance results both at the clinical and technological level.
Keywords: CONTEXTUAL CLASSIFICATION; PET/CT; SUPERVISED LEARNING; TUMOR SEGMENTATION; WHOLE BODY
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Frederic Sampedro, Anna Domenech, & Sergio Escalera. (2014). Static and dynamic computational cancer spread quantification in whole body FDG-PET/CT scans. JMIHI - Journal of Medical Imaging and Health Informatics, 4(6), 825–831.
Abstract: In this work we address the computational cancer spread quantification scenario in whole body FDG-PET/CT scans. At the static level, this setting can be modeled as a clustering problem on the set of 3D connected components of the whole body PET tumoral segmentation mask carried out by nuclear medicine physicians. At the dynamic level, and ad-hoc algorithm is proposed in order to quantify the cancer spread time evolution which, when combined with other existing indicators, gives rise to the metabolic tumor volume-aggressiveness-spread time evolution chart, a novel tool that we claim that would prove useful in nuclear medicine and oncological clinical or research scenarios. Good performance results of the proposed methodologies both at the clinical and technological level are shown using a dataset of 48 segmented whole body FDG-PET/CT scans.
Keywords: CANCER SPREAD; COMPUTER AIDED DIAGNOSIS; MEDICAL IMAGING; TUMOR QUANTIFICATION
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Jordi Esquirol, Cristina Palmero, Vanessa Bayo, Miquel Angel Cos, Sergio Escalera, David Sanchez, et al. (2017). Automatic RBG-depth-pressure anthropometric analysis and individualised sleep solution prescription. JMET - Journal of Medical Engineering & Technology, 486–497.
Abstract: INTRODUCTION:
Sleep surfaces must adapt to individual somatotypic features to maintain a comfortable, convenient and healthy sleep, preventing diseases and injuries. Individually determining the most adequate rest surface can often be a complex and subjective question.
OBJECTIVES:
To design and validate an automatic multimodal somatotype determination model to automatically recommend an individually designed mattress-topper-pillow combination.
METHODS:
Design and validation of an automated prescription model for an individualised sleep system is performed through a single-image 2 D-3 D analysis and body pressure distribution, to objectively determine optimal individual sleep surfaces combining five different mattress densities, three different toppers and three cervical pillows.
RESULTS:
A final study (n = 151) and re-analysis (n = 117) defined and validated the model, showing high correlations between calculated and real data (>85% in height and body circumferences, 89.9% in weight, 80.4% in body mass index and more than 70% in morphotype categorisation).
CONCLUSIONS:
Somatotype determination model can accurately prescribe an individualised sleep solution. This can be useful for healthy people and for health centres that need to adapt sleep surfaces to people with special needs. Next steps will increase model's accuracy and analise, if this prescribed individualised sleep solution can improve sleep quantity and quality; additionally, future studies will adapt the model to mattresses with technological improvements, tailor-made production and will define interfaces for people with special needs.
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Carlos Martin Isla, Victor M Campello, Cristian Izquierdo, Kaisar Kushibar, Carla Sendra Balcells, Polyxeni Gkontra, et al. (2023). Deep Learning Segmentation of the Right Ventricle in Cardiac MRI: The M&ms Challenge. JBHI - IEEE Journal of Biomedical and Health Informatics, 27(7), 3302–3313.
Abstract: In recent years, several deep learning models have been proposed to accurately quantify and diagnose cardiac pathologies. These automated tools heavily rely on the accurate segmentation of cardiac structures in MRI images. However, segmentation of the right ventricle is challenging due to its highly complex shape and ill-defined borders. Hence, there is a need for new methods to handle such structure's geometrical and textural complexities, notably in the presence of pathologies such as Dilated Right Ventricle, Tricuspid Regurgitation, Arrhythmogenesis, Tetralogy of Fallot, and Inter-atrial Communication. The last MICCAI challenge on right ventricle segmentation was held in 2012 and included only 48 cases from a single clinical center. As part of the 12th Workshop on Statistical Atlases and Computational Models of the Heart (STACOM 2021), the M&Ms-2 challenge was organized to promote the interest of the research community around right ventricle segmentation in multi-disease, multi-view, and multi-center cardiac MRI. Three hundred sixty CMR cases, including short-axis and long-axis 4-chamber views, were collected from three Spanish hospitals using nine different scanners from three different vendors, and included a diverse set of right and left ventricle pathologies. The solutions provided by the participants show that nnU-Net achieved the best results overall. However, multi-view approaches were able to capture additional information, highlighting the need to integrate multiple cardiac diseases, views, scanners, and acquisition protocols to produce reliable automatic cardiac segmentation algorithms.
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Antonio Hernandez, Nadezhda Zlateva, Alexander Marinov, Miguel Reyes, Petia Radeva, Dimo Dimov, et al. (2012). Human Limb Segmentation in Depth Maps based on Spatio-Temporal Graph Cuts Optimization. JAISE - Journal of Ambient Intelligence and Smart Environments, 4(6), 535–546.
Abstract: We present a framework for object segmentation using depth maps based on Random Forest and Graph-cuts theory, and apply it to the segmentation of human limbs. First, from a set of random depth features, Random Forest is used to infer a set of label probabilities for each data sample. This vector of probabilities is used as unary term in α−β swap Graph-cuts algorithm. Moreover, depth values of spatio-temporal neighboring data points are used as boundary potentials. Results on a new multi-label human depth data set show high performance in terms of segmentation overlapping of the novel methodology compared to classical approaches.
Keywords: Multi-modal vision processing; Random Forest; Graph-cuts; multi-label segmentation; human body segmentation
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