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Oriol Rodriguez-Leon, Debora Gil, Eduard Fernandez-Nofrerias, H.Tizon, S.Montserrat, Vicente del Valle, et al. (2007)." Caracterització de la Perfusió Miocàrdica mitjançant anàlisi estadístic de l espectre en l angiografia de contrast" In XIX Congrés de la Societat Catalana de Cardiologia de Barcelona (130). Barcelona (Spain).
Abstract: La valoració de la integritat de la microcirculació coronària aporta informació pronòstica en pacients amb infart agut de miocardi en els que es realitza angioplastia primària. Aquesta valoració és subjectiva i presenta una important variabilitat si no es duta a terme per personal experimentat. Presentem una eina d’anàlisi d’imatge que permet fer una valoració de la microcirculació coronària a partir de seqüències d’angiografia. Hem analitzat les variacions locals en el nivell de gris de la imatge durant la seqüència angiogràfica. Hem identificat els principals fenòmens observats (respiració, batec cardíac, tinció arterial, tinció miocàrdica i soroll radiològic) mitjançant un anàlisi estadístic de l’espectre de Fourier de l’evolució al llarg del temps de la mitja local. Aquest mateix anàlisis permet determinat la influència de cadascun d’ells en la extracció del patró de tinció i selecciona la respiració com el fenomen que més distorsiona el patró de tinció original. Els descriptors proposats s’obtenen fora del rang espectral respiratori. Hem testat la seva capacitat per a detectar els tres fenòmens principals (tinció miocàrdica (MS), tinció arterial (AS) i soroll (NS)) independentment de la respiració. La capacitat de discriminació dels descriptors ha estat valorada mitjançant un mètode de crossvalidation en 30 seqüències d’angiografia. Els descriptors emprats permeten caracteritzar la tinció miocàrdica amb una alta eficiència i fiabilitat. A més no hi ha diferències significatives en l’anàlisi de les seqüències obtingudes amb el pacient respirant amb normalitat o en apnea
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Sonia Baeza, Debora Gil, Carles Sanchez, Guillermo Torres, Ignasi Garcia Olive, Ignasi Guasch, et al. (2023)." Biopsia virtual radiomica para el diagnóstico histológico de nódulos pulmonares – Resultados intermedios del proyecto Radiolung" In SEPAR.
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Carles Sanchez, Miguel Viñas, Coen Antens, Agnes Borras, & Debora Gil. (2018). "Back to Front Architecture for Diagnosis as a Service " In 20th International Symposium on Symbolic and Numeric Algorithms for Scientific Computing (pp. 343–346).
Abstract: Software as a Service (SaaS) is a cloud computing model in which a provider hosts applications in a server that customers use via internet. Since SaaS does not require to install applications on customers' own computers, it allows the use by multiple users of highly specialized software without extra expenses for hardware acquisition or licensing. A SaaS tailored for clinical needs not only would alleviate licensing costs, but also would facilitate easy access to new methods for diagnosis assistance. This paper presents a SaaS client-server architecture for Diagnosis as a Service (DaaS). The server is based on docker technology in order to allow execution of softwares implemented in different languages with the highest portability and scalability. The client is a content management system allowing the design of websites with multimedia content and interactive visualization of results allowing user editing. We explain a usage case that uses our DaaS as crowdsourcing platform in a multicentric pilot study carried out to evaluate the clinical benefits of a software for assessment of central airway obstruction.
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Josefina Mauri, Eduard Fernandez-Nofrerias, J. Comin, B. Garcia del Blanco, E. Iraculis, J.A. Gomez-Hospital, et al. (2000)." Avaluació del Conjunt Stent/Artèria mitjançant ecografia intracoronària: lentorn informàtic" In Congrés de la Societat Catalana de Cardiologia..
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Debora Gil, Petia Radeva, Jordi Saludes, & Josefina Mauri. (2000). "Automatic Segmentation of Artery Wall in Coronary IVUS Images: A Probabilistic Approach " In International Conference on Pattern Recognition (Vol. 4, pp. 352–355).
Abstract: Intravascular ultrasound images represent a unique tool to analyze the morphology of arteries and vessels (plaques, restenosis, etc). The poor quality of these images makes unsupervised segmentation based on traditional segmentation algorithms (such as edge or ridge/valley detection) fail to achieve the expected results. In this paper we present a probabilistic flexible template to separate different regions in the image. In particular, we use elliptic templates to model and detect the shape of the vessel inner wall in IVUS images. We present the results of successful segmentation obtained from patients undergoing stent treatment. A physician team has validated these results.
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Debora Gil, Petia Radeva, Jordi Saludes, & Josefina Mauri. (2000). "Automatic Segmentation of Artery Wall in Coronary IVUS Images: a Probabilistic Approach " In Proceedings of CIC’2000. Cambridge, Massachussets.
Abstract: Intravascular ultrasound images represent a unique tool to analyze the morphology of arteries and vessels (plaques, restenosis, etc). The poor quality of these images makes unsupervised segmentation based on traditional segmentation algorithms (such as edge or ridge/valley detection) fail to achieve the expected results. In this paper we present a probabilistic flexible template to separate different regions in the image. In particular, we use elliptic templates to model and detect the shape of the vessel inner wall in IVUS images. We present the results of successful segmentation obtained from patients undergoing stent treatment. A physician team has validated these results.
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David Roche, Debora Gil, & Jesus Giraldo. (2012). "Assessing agonist efficacy in an uncertain Em world " In A. Christopoulus and M. Bouvier (Ed.), 40th Keystone Symposia on mollecular and celular biology (79). Keystone Symposia.
Abstract: The operational model of agonism has been widely used for the analysis of agonist action since its formulation in 1983. The model includes the Em parameter, which is defined as the maximum response of the system. The methods for Em estimation provide Em values not significantly higher than the maximum responses achieved by full agonists. However, it has been found that that some classes of compounds as, for instance, superagonists and positive allosteric modulators can increase the full agonist maximum response, implying upper limits for Em and thereby posing doubts on the validity of Em estimates. Because of the correlation between Em and operational efficacy, τ, wrong Em estimates will yield wrong τ estimates.
In this presentation, the operational model of agonism and various methods for the simulation of allosteric modulation will be analyzed. Alternatives for curve fitting will be presented and discussed.
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Ernest Valveny, & Enric Marti. (1999). "Application of deformable template matching to symbol recognition in hand-written architectural draw " In Proceedings of the Fifth International Conference on. Bangalore (India).
Abstract: We propose to use deformable template matching as a new approach to recognize characters and lineal symbols in hand-written line drawings, instead of traditional methods based on vectorization and feature extraction. Bayesian formulation of the deformable template matching allows combining fidelity to the ideal shape of the symbol with maximum flexibility to get the best fit to the input image. Lineal nature of symbols can be exploited to define a suitable representation of models and the set of deformations to be applied to them. Matching, however, is done over the original binary image to avoid losing relevant features during vectorization. We have applied this method to hand-written architectural drawings and experimental results demonstrate that symbols with high distortions from ideal shape can be accurately identified.
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Aura Hernandez-Sabate, Debora Gil, Petia Radeva, & E.N.Nofrerias. (2004). "Anisotropic processing of image structures for adventitia detection in intravascular ultrasound images " In Proc. Computers in Cardiology (Vol. 31, pp. 229–232). Chicago (USA).
Abstract: The adventitia layer appears as a weak edge in IVUS images with a non-uniform grey level, which difficulties its detection. In order to enhance edges, we apply an anisotropic filter that homogenizes the grey level along the image significant structures (ridges, valleys and edges). A standard edge detector applied to the filtered image yields a set of candidate points prone to be unconnected. The final model is obtained by interpolating the former line segments along the tangent direction to the level curves of the filtered image with an anisotropic contour closing technique based on functional extension principles
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Debora Gil, Petia Radeva, & Fernando Vilariño. (2003). "Anisotropic Contour Completion " In Proceedings of the IEEE International Conference on Image Processing. Barcelona, Spain.
Abstract: In this paper we introduce a novel application of the diffusion tensor for anisotropic image processing. The Anisotropic Contour Completion (ACC) we suggest consists in extending the characteristic function of the open curve by means of a degenerated diffusion tensor that prevents any diffusion in the normal direction. We show that ACC is equivalent to a dilation with a continuous elliptic structural element that takes into account the local orientation of the contours to be closed. Experiments on contours extracted from real images show that ACC produces shapes able to adapt to any curve in an active contour framework. 1.
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