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Fernando Vilariño; Panagiota Spyridonos; Fosca De Iorio; Jordi Vitria; Fernando Azpiroz; Petia Radeva |
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Title |
Intestinal Motility Assessment With Video Capsule Endoscopy: Automatic Annotation of Phasic Intestinal Contractions |
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Year |
2010 |
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IEEE Transactions on Medical Imaging |
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TMI |
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29 |
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2 |
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246-259 |
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Abstract |
Intestinal motility assessment with video capsule endoscopy arises as a novel and challenging clinical fieldwork. This technique is based on the analysis of the patterns of intestinal contractions shown in a video provided by an ingestible capsule with a wireless micro-camera. The manual labeling of all the motility events requires large amount of time for offline screening in search of findings with low prevalence, which turns this procedure currently unpractical. In this paper, we propose a machine learning system to automatically detect the phasic intestinal contractions in video capsule endoscopy, driving a useful but not feasible clinical routine into a feasible clinical procedure. Our proposal is based on a sequential design which involves the analysis of textural, color, and blob features together with SVM classifiers. Our approach tackles the reduction of the imbalance rate of data and allows the inclusion of domain knowledge as new stages in the cascade. We present a detailed analysis, both in a quantitative and a qualitative way, by providing several measures of performance and the assessment study of interobserver variability. Our system performs at 70% of sensitivity for individual detection, whilst obtaining equivalent patterns to those of the experts for density of contractions. |
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0278-0062 |
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800 |
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MILAB;MV;OR;SIAI |
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BCNPCL @ bcnpcl @ VSD2010; IAM @ iam @ VSI2010 |
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1281 |
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Author |
Fosca De Iorio; C. Malagelada; Fernando Azpiroz; M. Maluenda; C. Violanti; Laura Igual; Jordi Vitria; Juan R. Malagelada |
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Title |
Intestinal motor activity, endoluminal motion and transit |
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Journal Article |
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2009 |
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Neurogastroenterology & Motility |
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NEUMOT |
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21 |
Issue |
12 |
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1264–e119 |
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A programme for evaluation of intestinal motility has been recently developed based on endoluminal image analysis using computer vision methodology and machine learning techniques. Our aim was to determine the effect of intestinal muscle inhibition on wall motion, dynamics of luminal content and transit in the small bowel. Fourteen healthy subjects ingested the endoscopic capsule (Pillcam, Given Imaging) in fasting conditions. Seven of them received glucagon (4.8 microg kg(-1) bolus followed by a 9.6 microg kg(-1) h(-1) infusion during 1 h) and in the other seven, fasting activity was recorded, as controls. This dose of glucagon has previously shown to inhibit both tonic and phasic intestinal motor activity. Endoluminal image and displacement was analyzed by means of a computer vision programme specifically developed for the evaluation of muscular activity (contractile and non-contractile patterns), intestinal contents, endoluminal motion and transit. Thirty-minute periods before, during and after glucagon infusion were analyzed and compared with equivalent periods in controls. No differences were found in the parameters measured during the baseline (pretest) periods when comparing glucagon and control experiments. During glucagon infusion, there was a significant reduction in contractile activity (0.2 +/- 0.1 vs 4.2 +/- 0.9 luminal closures per min, P < 0.05; 0.4 +/- 0.1 vs 3.4 +/- 1.2% of images with radial wrinkles, P < 0.05) and a significant reduction of endoluminal motion (82 +/- 9 vs 21 +/- 10% of static images, P < 0.05). Endoluminal image analysis, by means of computer vision and machine learning techniques, can reliably detect reduced intestinal muscle activity and motion. |
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OR;MILAB;MV |
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BCNPCL @ bcnpcl @ DMA2009 |
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1251 |
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Francesco Ciompi; Oriol Pujol; Carlo Gatta; Marina Alberti; Simone Balocco; Xavier Carrillo; J. Mauri; Petia Radeva |
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Title |
HoliMab: A Holistic Approach for Media-Adventitia Border Detection in Intravascular Ultrasound |
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2012 |
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Medical Image Analysis |
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MIA |
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16 |
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6 |
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1085-1100 |
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Media–Adventitia border detection; Intravascular ultrasound; Multi-Scale Stacked Sequential Learning; Error-correcting output codes; Holistic segmentation |
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We present a fully automatic methodology for the detection of the Media-Adventitia border (MAb) in human coronary artery in Intravascular Ultrasound (IVUS) images. A robust border detection is achieved by means of a holistic interpretation of the detection problem where the target object, i.e. the media layer, is considered as part of the whole vessel in the image and all the relationships between tissues are learnt. A fairly general framework exploiting multi-class tissue characterization as well as contextual information on the morphology and the appearance of the tissues is presented. The methodology is (i) validated through an exhaustive comparison with both Inter-observer variability on two challenging databases and (ii) compared with state-of-the-art methods for the detection of the MAb in IVUS. The obtained averaged values for the mean radial distance and the percentage of area difference are 0.211 mm and 10.1%, respectively. The applicability of the proposed methodology to clinical practice is also discussed. |
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MILAB;HuPBA |
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Admin @ si @ CPG2012 |
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1995 |
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Francesco Ciompi; Oriol Pujol; Carlo Gatta; O. Rodriguez-Leor; J. Mauri; Petia Radeva |
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Title |
Fusing in-vitro and in-vivo intravascular ultrasound data for plaque characterization |
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2010 |
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International Journal of Cardiovascular Imaging |
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IJCI |
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26 |
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7 |
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763–779 |
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Accurate detection of in-vivo vulnerable plaque in coronary arteries is still an open problem. Recent studies show that it is highly related to tissue structure and composition. Intravascular Ultrasound (IVUS) is a powerful imaging technique that gives a detailed cross-sectional image of the vessel, allowing to explore arteries morphology. IVUS data validation is usually performed by comparing post-mortem (in-vitro) IVUS data and corresponding histological analysis of the tissue. The main drawback of this method is the few number of available case studies and validated data due to the complex procedure of histological analysis of the tissue. On the other hand, IVUS data from in-vivo cases is easy to obtain but it can not be histologically validated. In this work, we propose to enhance the in-vitro training data set by selectively including examples from in-vivo plaques. For this purpose, a Sequential Floating Forward Selection method is reformulated in the context of plaque characterization. The enhanced classifier performance is validated on in-vitro data set, yielding an overall accuracy of 91.59% in discriminating among fibrotic, lipidic and calcified plaques, while reducing the gap between in-vivo and in-vitro data analysis. Experimental results suggest that the obtained classifier could be properly applied on in-vivo plaque characterization and also demonstrate that the common hypothesis of assuming the difference between in-vivo and in-vitro as negligible is incorrect. |
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1569-5794 |
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MILAB;HUPBA |
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BCNPCL @ bcnpcl @ CPG2010 |
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1305 |
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Author |
Francesco Ciompi; Oriol Pujol; Petia Radeva |
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Title |
ECOC-DRF: Discriminative random fields based on error correcting output codes |
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Journal Article |
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2014 |
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Pattern Recognition |
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PR |
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47 |
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6 |
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2193-2204 |
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Discriminative random fields; Error-correcting output codes; Multi-class classification; Graphical models |
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We present ECOC-DRF, a framework where potential functions for Discriminative Random Fields are formulated as an ensemble of classifiers. We introduce the label trick, a technique to express transitions in the pairwise potential as meta-classes. This allows to independently learn any possible transition between labels without assuming any pre-defined model. The Error Correcting Output Codes matrix is used as ensemble framework for the combination of margin classifiers. We apply ECOC-DRF to a large set of classification problems, covering synthetic, natural and medical images for binary and multi-class cases, outperforming state-of-the art in almost all the experiments. |
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LAMP; HuPBA; MILAB; 605.203; 600.046; 601.043; 600.079 |
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Admin @ si @ CPR2014b |
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2470 |
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