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Author |
Debora Gil; Jaume Garcia; Manuel Vazquez; Ruth Aris; Guillaume Houzeaux |
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Title |
Patient-Sensitive Anatomic and Functional 3D Model of the Left Ventricle Function |
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2008 |
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8th World Congress on Computational Mechanichs (WCCM8)/5th European Congress on Computational Methods in Applied Sciences and Engineering (ECCOMAS 2008) |
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Left Ventricle; Electromechanical Models; Image Processing; Magnetic Resonance. |
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Early diagnosis and accurate treatment of Left Ventricle (LV) dysfunction significantly increases the patient survival. Impairment of LV contractility due to cardiovascular diseases is reflected in its motion patterns. Recent advances in medical imaging, such as Magnetic Resonance (MR), have encouraged research on 3D simulation and modelling of the LV dynamics. Most of the existing 3D models consider just the gross anatomy of the LV and restore a truncated ellipse which deforms along the cardiac cycle. The contraction mechanics of any muscle strongly depends on the spatial orientation of its muscular fibers since the motion that the muscle undergoes mainly takes place along the fibers. It follows that such simplified models do not allow evaluation of the heart electro-mechanical function and coupling, which has recently risen as the key point for understanding the LV functionality . In order to thoroughly understand the LV mechanics it is necessary to consider the complete anatomy of the LV given by the orientation of the myocardial fibres in 3D space as described by Torrent Guasp. We propose developing a 3D patient-sensitive model of the LV integrating, for the first time, the ven- tricular band anatomy (fibers orientation), the LV gross anatomy and its functionality. Such model will represent the LV function as a natural consequence of its own ventricular band anatomy. This might be decisive in restoring a proper LV contraction in patients undergoing pace marker treatment. The LV function is defined as soon as the propagation of the contractile electromechanical pulse has been modelled. In our experiments we have used the wave equation for the propagation of the electric pulse. The electromechanical wave moves on the myocardial surface and should have a conductivity tensor oriented along the muscular fibers. Thus, whatever mathematical model for electric pulse propa- gation [4] we consider, the complete anatomy of the LV should be extracted. The LV gross anatomy is obtained by processing multi slice MR images recorded for each patient. Information about the myocardial fibers distribution can only be extracted by Diffusion Tensor Imag- ing (DTI), which can not provide in vivo information for each patient. As a first approach, we have computed an average model of fibers from several DTI studies of canine hearts. This rough anatomy is the input for our electro-mechanical propagation model simulating LV dynamics. The average fiber orientation is updated until the simulated LV motion agrees with the experimental evidence provided by the LV motion observed in tagged MR (TMR) sequences. Experimental LV motion is recovered by applying image processing, differential geometry and interpolation techniques to 2D TMR slices [5]. The pipeline in figure 1 outlines the interaction between simulations and experimental data leading to our patient-tailored model. |
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Venezia (Italia) |
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B-31470-08 |
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IAM @ iam @ GGV2008c |
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1521 |
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Author |
Debora Gil; Oriol Rodriguez-Leor; Petia Radeva; J. Mauri |
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Title |
Myocardial Perfusion Characterization From Contrast Angiography Spectral Distribution |
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2008 |
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IEEE Transactions on Medical Imaging |
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27 |
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5 |
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641-649 |
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Contrast angiography; myocardial perfusion; spectral analysis. |
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Despite recovering a normal coronary flow after acute myocardial infarction, percutaneous coronary intervention does not guarantee a proper perfusion (irrigation) of the infarcted area. This damage in microcirculation integrity may detrimentally affect the patient survival. Visual assessment of the myocardium opacification in contrast angiography serves to define a subjective score of the microcirculation integrity myocardial blush analysis (MBA). Although MBA correlates with patient prognosis its visual assessment is a very difficult task that requires of a highly expertise training in order to achieve a good intraobserver and interobserver agreement. In this paper, we provide objective descriptors of the myocardium staining pattern by analyzing the spectrum of the image local statistics. The descriptors proposed discriminate among the different phenomena observed in the angiographic sequence and allow defining an objective score of the myocardial perfusion. |
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IAM @ iam @ GRR2008 |
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1541 |
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Author |
Aura Hernandez-Sabate; David Rotger; Debora Gil |
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Title |
Image-based ECG sampling of IVUS sequences |
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2008 |
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Proc. IEEE Ultrasonics Symp. IUS 2008 |
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1330-1333 |
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Longitudinal Motion; Image-based ECG-gating; Fourier analysis |
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Longitudinal motion artifacts in IntraVascular UltraSound (IVUS) sequences hinders a properly 3D reconstruction and vessel measurements. Most of current techniques base on the ECG signal to obtain a gated pullback without the longitudinal artifact by using a specific hardware or the ECG signal itself. The potential of IVUS images processing for phase retrieval still remains little explored. In this paper, we present a fast forward image-based algorithm to approach ECG sampling. Inspired on the fact that maximum and minimum lumen areas are related to end-systole and end-diastole, our cardiac phase retrieval is based on the analysis of tissue density of mass along the sequence. The comparison between automatic and manual phase retrieval (0.07 ± 0.07 mm. of error) encourages a deep validation contrasting with ECG signals. |
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Beijing (China) |
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IAM @ iam @ HRG2008 |
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1553 |
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Author |
Enric Marti |
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Aplicació de la metodología d’Aprenentatge basat en Proyectes en l’assignatura de Gràfics per Computador d’enginyeria Informàtica. Balanç de Quatre anys d’experiència |
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2008 |
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revista EINES |
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6 |
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85-99 |
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IAM @ iam @ MAR2008b |
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1585 |
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Author |
Enric Marti |
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Project Based Learning in engineering |
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2008 |
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Simposium on Problem Based learning (PBL) |
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Lleida |
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IAM @ iam @ MAR2008a |
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1586 |
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Enric Marti; Xavier Binefa; G.EstapeRV |
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Caronte, plataforma para la gestión de la actividad docente de una asignatura. Análisis de su impacto en ingenierías, para su adaptación al EEES |
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2008 |
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, Ministerio de Ciencia e Innovacion, DGU |
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Direccion General de Universidades |
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IAM;OR;RV |
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IAM @ iam @ MBE2008 |
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1589 |
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Enric Marti; G.Estape; S.Fernandez |
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Bluestar: Diseño e implementación de una aplicación para la visualización interactiva en 3D de funciones reales como herramienta de aprendizaje |
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2008 |
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V Congreso Internacional Docencia Universitaria e Innovación |
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Lleida |
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IAM @ iam @ MEF2008 |
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1590 |
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Enric Marti; Debora Gil; Carme Julia |
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Title |
Experiencia d aplicació de la metodología d aprenentatge per proyectes en assignatures d Enginyeria Informàtica per a una millor adaptació als crèdits ECTS i EEES |
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2008 |
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Experiències docents innovadores de la UAB en ciències experimentals i tecnologies i en ciències de la salud |
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1 |
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57-68 |
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UAB |
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IDES-UAB; M.Enric Martinez, E.A. |
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978-84-490-2576-1 |
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IAM;ADAS; |
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IAM @ iam @ MGJ2008 |
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1592 |
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Enric Marti; Debora Gil; Marc Vivet ; Carme Julia |
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Balance de cuatro años de experiencia en la implantación de la metodología de Aprendizaje Basado en Proyectos en la asignatura de Gráficos por Computador en ingeniería Informática |
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2008 |
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Actas V Jornadas Internacionales de Innovación Universitaria |
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Aprendizaje cooperativo; aprendizaje basado en proyectos; experiencias docentes. |
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En este trabajo se presentan los resultados de la aplicación de la metodología del aprendizaje cooperativo a la docencia de dos asignaturas de programación en ingeniería informática. ‘Algoritmos y programación’ y ‘Lenguajes de programación’ son dos asignaturas complementarias que se organizan entorno a un proyecto común que engloba los contenidos de ambas asignaturas. En la docencia de una parte muy importante de estas asignaturas, la metodología del aprendizaje cooperativo se ha adaptado a sus características específicas. Como muestra de esta adaptación presentamos dos ejemplos de las actividades desarrolladas dentro de la docencia de estas asignaturas. Después de tres años de aplicación, el análisis a nivel cualitativo y cuantitativo de los resultados muestra que éstos son muy satisfactorios y que la aplicación del método cooperativo ha mejorado de forma considerable el rendimiento de los alumnos en ambas asignaturas. |
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IAM;ADAS |
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IAM @ iam @ MGV2008a |
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1598 |
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Enric Marti; Debora Gil; Marc Vivet; Carme Julia |
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Balance de cuatro años de experiencia en la implantación de la metodología de Aprendizaje Basado en Proyectos en la asignatura de Gráficos por Computador en ingeniería Informática |
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2008 |
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VIII Jornadas de Innovación Universitaria |
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IAM @ iam @ MGV2008b |
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1599 |
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