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Author Ester Conde; Susana Herandez; Rebeca Martinez; Barbara Angulo; Javier de Castro; Ana Collazo; Beatriz Jimenez; Alfonso Muriel; Jose Luis Mate; Teresa Moran; Ignacio Aranda; Bartomeu Massuti; Federico Rojo; Manuel Domine; Irene Sansano; Felipe Garcia; Enriqueta Felip; Nuria Mancheno; Oscar Juan; Julian Sanz; Jose Luis Gonzalez; Lidia Atienza; Esperanza Arriola; I. Abdulkader; J.Garcia; C. Camacho; D. Rodriguez; D. Teixido; N. Reguart; A.Gonzalez; M. Lazaro; MD. Lozano; J. Gomez; M. Lopez; L Pijuan; M Salido; E. Arriola; A. Company; A. Insa; I. Esteban; M. Saiz; E. Azkona; R. Alvarez; A. Artal; ML. Plaza; D. Aguiar; AB. Enguita, A. Benito; L. Paz; P. Garrido; F. Lopez edit  url
doi  openurl
  Title Assessment of a New ROS1 Immunohistochemistry Clone (SP384) for the Identification of ROS1 Rearrangements in Patients with Non–Small Cell Lung Carcinoma: the ROSING Study Type Journal Article
  Year 2019 Publication Journal of Thoracic Oncology Abbreviated Journal  
  Volume 14 Issue (up) 12 Pages 2120-2132  
  Keywords  
  Abstract Introduction
The ROS1 gene rearrangement has become an important biomarker in NSCLC. The College of American Pathologists/International Association for the Study of Lung Cancer/Association for Molecular Pathology testing guidelines support the use of ROS1 immunohistochemistry (IHC) as a screening test, followed by confirmation with fluorescence in situ hybridization (FISH) or a molecular test in all positive results. We have evaluated a novel anti-ROS1 IHC antibody (SP384) in a large multicenter series to obtain real-world data.

Methods
A total of 43 ROS1 FISH–positive and 193 ROS1 FISH–negative NSCLC samples were studied. All specimens were screened by using two antibodies (clone D4D6 from Cell Signaling Technology and clone SP384 from Ventana Medical Systems), and the different interpretation criteria were compared with break-apart FISH (Vysis). FISH-positive samples were also analyzed with next-generation sequencing (Oncomine Dx Target Test Panel, Thermo Fisher Scientific).

Results
An H-score of 150 or higher or the presence of at least 70% of tumor cells with an intensity of staining of 2+ or higher by the SP384 clone was the optimal cutoff value (both with 93% sensitivity and 100% specificity). The D4D6 clone showed similar results, with an H-score of at least 100 (91% sensitivity and 100% specificity). ROS1 expression in normal lung was more frequent with use of the SP384 clone (p < 0.0001). The ezrin gene (EZR)-ROS1 variant was associated with membranous staining and an isolated green signal FISH pattern (p = 0.001 and p = 0.017, respectively).

Conclusions
The new SP384 ROS1 IHC clone showed excellent sensitivity without compromising specificity, so it is another excellent analytical option for the proposed testing algorithm.
 
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  ISSN ISBN Medium  
  Area Expedition Conference  
  Notes IAM; 600.139; 600.145 Approved no  
  Call Number Admin @ si @ CHM2019 Serial 3471  
Permanent link to this record
 

 
Author Josep Llados; Horst Bunke; Enric Marti edit   pdf
url  doi
openurl 
  Title Finding rotational symmetries by cyclic string matching Type Journal Article
  Year 1997 Publication Pattern recognition letters Abbreviated Journal PRL  
  Volume 18 Issue (up) 14 Pages 1435-1442  
  Keywords Rotational symmetry; Reflectional symmetry; String matching  
  Abstract Symmetry is an important shape feature. In this paper, a simple and fast method to detect perfect and distorted rotational symmetries of 2D objects is described. The boundary of a shape is polygonally approximated and represented as a string. Rotational symmetries are found by cyclic string matching between two identical copies of the shape string. The set of minimum cost edit sequences that transform the shape string to a cyclically shifted version of itself define the rotational symmetry and its order. Finally, a modification of the algorithm is proposed to detect reflectional symmetries. Some experimental results are presented to show the reliability of the proposed algorithm  
  Address  
  Corporate Author Thesis  
  Publisher Elsevier Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference  
  Notes DAG;IAM; Approved no  
  Call Number IAM @ iam @ LBM1997a Serial 1562  
Permanent link to this record
 

 
Author Ernest Valveny; Enric Marti edit   pdf
doi  openurl
  Title A model for image generation and symbol recognition through the deformation of lineal shapes Type Journal Article
  Year 2003 Publication Pattern Recognition Letters Abbreviated Journal PRL  
  Volume 24 Issue (up) 15 Pages 2857-2867  
  Keywords  
  Abstract We describe a general framework for the recognition of distorted images of lineal shapes, which relies on three items: a model to represent lineal shapes and their deformations, a model for the generation of distorted binary images and the combination of both models in a common probabilistic framework, where the generation of deformations is related to an internal energy, and the generation of binary images to an external energy. Then, recognition consists in the minimization of a global energy function, performed by using the EM algorithm. This general framework has been applied to the recognition of hand-drawn lineal symbols in graphic documents.  
  Address  
  Corporate Author Thesis  
  Publisher Elsevier Science Inc. Place of Publication New York, NY, USA Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0167-8655 ISBN Medium  
  Area Expedition Conference  
  Notes DAG; IAM Approved no  
  Call Number IAM @ iam @ VAM2003 Serial 1653  
Permanent link to this record
 

 
Author Josep Llados; Gemma Sanchez; Enric Marti edit   pdf
doi  openurl
  Title A string based method to recognize symbols and structural textures in architectural plans Type Book Chapter
  Year 1998 Publication Graphics Recognition Algorithms and Systems Second International Workshop, GREC' 97 Nancy, France, August 22–23, 1997 Selected Papers Abbreviated Journal LNCS  
  Volume 1389 Issue (up) 1998 Pages 91-103  
  Keywords  
  Abstract This paper deals with the recognition of symbols and structural textures in architectural plans using string matching techniques. A plan is represented by an attributed graph whose nodes represent characteristic points and whose edges represent segments. Symbols and textures can be seen as a set of regions, i.e. closed loops in the graph, with a particular arrangement. The search for a symbol involves a graph matching between the regions of a model graph and the regions of the graph representing the document. Discriminating a texture means a clustering of neighbouring regions of this graph. Both procedures involve a similarity measure between graph regions. A string codification is used to represent the sequence of outlining edges of a region. Thus, the similarity between two regions is defined in terms of the string edit distance between their boundary strings. The use of string matching allows the recognition method to work also under presence of distortion.  
  Address  
  Corporate Author Thesis  
  Publisher Springer Link Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title LNCS Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference  
  Notes DAG; IAM Approved no  
  Call Number IAM @ iam @ SLE1998 Serial 1573  
Permanent link to this record
 

 
Author Marta Diez-Ferrer; Debora Gil; Elena Carreño; Susana Padrones; Samantha Aso edit  url
openurl 
  Title Positive Airway Pressure-Enhanced CT to Improve Virtual Bronchoscopic Navigation Type Journal Article
  Year 2017 Publication Journal of Thoracic Oncology Abbreviated Journal JTO  
  Volume 12 Issue (up) 1S Pages S596-S597  
  Keywords Thorax CT; diagnosis; Peripheral Pulmonary Nodule  
  Abstract A main weakness of virtual bronchoscopic navigation (VBN) is unsuccessful segmentation of distal branches approaching peripheral pulmonary nodules (PPN). CT scan acquisition protocol is pivotal for segmentation covering the utmost periphery. We hypothesize that application of continuous positive airway pressure (CPAP) during CT acquisition could improve visualization and segmentation of peripheral bronchi. The purpose of the present pilot study is to compare quality of segmentations under 4 CT acquisition modes: inspiration (INSP), expiration (EXP) and both with CPAP (INSP-CPAP and EXP-CPAP).  
  Address  
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  Publisher Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference  
  Notes IAM; 600.096; 600.075; 600.145 Approved no  
  Call Number Admin @ si @ DGC2017a Serial 2883  
Permanent link to this record
 

 
Author Oriol Rodriguez-Leon; Josefina Mauri;Eduard Fernandez-Nofrerias; Antonio Tovar; Vicente del Valle; Aura Hernandez-Sabate; Debora Gil; Petia Radeva edit  openurl
  Title Utilizacion de la estructura de los campos vectoriales para la deteccion de la Adventicia en imagenes de Ecografia Intracoronaria Type Journal
  Year 2004 Publication Revista Española de Cardiología Abbreviated Journal REC  
  Volume 57 Issue (up) 2 Pages 100  
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  Abstract  
  Address  
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  Publisher Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference SEC  
  Notes MILAB;IAM Approved no  
  Call Number BCNPCL @ bcnpcl @ RMF2004 Serial 566  
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Author Francesc Carreras; Jaume Garcia; Debora Gil; Sandra Pujadas; Chi ho Lion; R.Suarez-Arias; R.Leta; Xavier Alomar; Manuel Ballester; Guillem Pons-Llados edit  url
doi  openurl
  Title Left ventricular torsion and longitudinal shortening: two fundamental components of myocardial mechanics assessed by tagged cine-MRI in normal subjects Type Journal Article
  Year 2012 Publication International Journal of Cardiovascular Imaging Abbreviated Journal IJCI  
  Volume 28 Issue (up) 2 Pages 273-284  
  Keywords Magnetic resonance imaging (MRI); Tagging MRI; Cardiac mechanics; Ventricular torsion  
  Abstract Cardiac magnetic resonance imaging (Cardiac MRI) has become a gold standard diagnostic technique for the assessment of cardiac mechanics, allowing the non-invasive calculation of left ventric- ular long axis longitudinal shortening (LVLS) and absolute myocardial torsion (AMT) between basal and apical left ventricular slices, a movement directly related to the helicoidal anatomic disposition of the myocardial fibers. The aim of this study is to determine AMT and LVLS behaviour and normal values from a group of healthy subjects. A group of 21 healthy volunteers (15 males) (age: 23–55 y.o., mean:30.7 ± 7.5) were prospectively included in an obser- vational study by Cardiac MRI. Left ventricular rotation (degrees) was calculated by custom-made software (Harmonic Phase Flow) in consecutive LV short axis planes tagged cine-MRI sequences. AMT was determined from the difference between basal and apical planes LV rotations. LVLS (%) was determined from the LV longitudinal and horizontal axis cine-MRI images. All the 21 cases studied were interpretable, although in three cases the value of the LV apical rotation could not be determined. The mean rotation of the basal and apical planes at end-systole were -3.71° ± 0.84° and 6.73° ± 1.69° (n:18) respectively, resulting in a LV mean AMT of 10.48° ± 1.63° (n:18). End-systolic mean LVLS was 19.07 ± 2.71%. Cardiac MRI allows for the calculation of AMT and LVLS, fundamental functional components of the ventricular twist mechanics conditioned, in turn, by the anatomical helical layout of the myocardial fibers. These values provide complementary information about systolic ventricular function in relation to the traditional parameters used in daily practice.  
  Address  
  Corporate Author Thesis  
  Publisher Springer Netherlands Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 1569-5794 ISBN Medium  
  Area Expedition Conference  
  Notes IAM; Approved no  
  Call Number IAM @ iam @ CGG2012 Serial 1496  
Permanent link to this record
 

 
Author Oriol Rodriguez-Leon; Debora Gil; Eduard Fernandez-Nofrerias edit  openurl
  Title Analisis en los cambios en el nivel de gris en las secuencias angiograficas mediante descriptores estadisticos para determinar la perfusion miocardica Type Journal Article
  Year 2006 Publication Revista Española de Cardiología Abbreviated Journal REC  
  Volume 59 Supl 2-166 Issue (up) 2 Pages 128  
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  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference  
  Notes IAM; Approved no  
  Call Number IAM @ iam @ RGF2006 Serial 1640  
Permanent link to this record
 

 
Author Oriol Rodriguez-Leon; Josefina Mauri;Eduard Fernandez-Nofrerias; Antonio Tovar; Vicente del Valle; Aura Hernandez-Sabate; Debora Gil; Petia Radeva edit  openurl
  Title Utilización de la Estructura de los Campos Vectoriales para la Detección de la Adventicia en Imágenes de Ecografía Intracoronaria Type Journal Article
  Year 2004 Publication Revista Internacional de Enfermedades Cardiovasculares Revista Española de Cardiología Abbreviated Journal  
  Volume 57 Issue (up) 2 Pages 100  
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  Abstract  
  Address  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference SEC  
  Notes IAM;MILAB Approved no  
  Call Number IAM @ iam @ RMF2004 Serial 1642  
Permanent link to this record
 

 
Author Patricia Marquez;Debora Gil;Aura Hernandez-Sabate edit   pdf
doi  isbn
openurl 
  Title A Complete Confidence Framework for Optical Flow Type Conference Article
  Year 2012 Publication 12th European Conference on Computer Vision – Workshops and Demonstrations Abbreviated Journal  
  Volume 7584 Issue (up) 2 Pages 124-133  
  Keywords Optical flow, confidence measures, sparsification plots, error prediction plots  
  Abstract Medial representations are powerful tools for describing and parameterizing the volumetric shape of anatomical structures. Existing methods show excellent results when applied to 2D objects, but their quality drops across dimensions. This paper contributes to the computation of medial manifolds in two aspects. First, we provide a standard scheme for the computation of medial manifolds that avoid degenerated medial axis segments; second, we introduce an energy based method which performs independently of the dimension. We evaluate quantitatively the performance of our method with respect to existing approaches, by applying them to synthetic shapes of known medial geometry. Finally, we show results on shape representation of multiple abdominal organs, exploring the use of medial manifolds for the representation of multi-organ relations.  
  Address  
  Corporate Author Thesis  
  Publisher Springer-Verlag Place of Publication Florence, Italy, October 7-13, 2012 Editor Andrea Fusiello, Vittorio Murino ,Rita Cucchiara  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title LNCS  
  Series Volume Series Issue Edition  
  ISSN ISBN 978-3-642-33867-0 Medium  
  Area Expedition Conference ECCVW  
  Notes IAM;ADAS; Approved no  
  Call Number IAM @ iam @ MGH2012b Serial 1991  
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