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Author Oriol Rodriguez-Leon; Josefina Mauri;Eduard Fernandez-Nofrerias; Antonio Tovar; Vicente del Valle; Aura Hernandez-Sabate; Debora Gil; Petia Radeva edit  openurl
  Title Utilización de la Estructura de los Campos Vectoriales para la Detección de la Adventicia en Imágenes de Ecografía Intracoronaria Type Journal Article
  Year 2004 Publication Revista Internacional de Enfermedades Cardiovasculares Revista Española de Cardiología Abbreviated Journal  
  Volume 57 Issue 2 Pages 100  
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  Area Expedition Conference SEC  
  Notes IAM;MILAB Approved no  
  Call Number IAM @ iam @ RMF2004 Serial 1642  
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Author Alberto Hidalgo; Ferran Poveda; Enric Marti;Debora Gil;Albert Andaluz; Francesc Carreras; Manuel Ballester edit   pdf
url  doi
openurl 
  Title Evidence of continuous helical structure of the cardiac ventricular anatomy assessed by diffusion tensor imaging magnetic resonance multiresolution tractography Type Journal Article
  Year 2012 Publication European Radiology Abbreviated Journal ECR  
  Volume 3 Issue 1 Pages 361-362  
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  Abstract Deep understanding of myocardial structure linking morphology and func- tion of the heart would unravel crucial knowledge for medical and surgical clinical procedures and studies. Diffusion tensor MRI provides a discrete measurement of the 3D arrangement of myocardial fibres by the observation of local anisotropic
diffusion of water molecules in biological tissues. In this work, we present a multi- scale visualisation technique based on DT-MRI streamlining capable of uncovering additional properties of the architectural organisation of the heart. Methods and Materials: We selected the John Hopkins University (JHU) Canine Heart Dataset, where the long axis cardiac plane is aligned with the scanner’s Z- axis. Their equipment included a 4-element passed array coil emitting a 1.5 T. For DTI acquisition, a 3D-FSE sequence is apply. We used 200 seeds for full-scale tractography, while we applied a MIP mapping technique for simplified tractographic reconstruction. In this case, we reduced each DTI 3D volume dimensions by order- two magnitude before streamlining.
Our simplified tractographic reconstruction method keeps the main geometric features of fibres, allowing for an easier identification of their global morphological disposition, including the ventricular basal ring. Moreover, we noticed a clearly visible helical disposition of the myocardial fibres, in line with the helical myocardial band ventricular structure described by Torrent-Guasp. Finally, our simplified visualisation with single tracts identifies the main segments of the helical ventricular architecture.
DT-MRI makes possible the identification of a continuous helical architecture of the myocardial fibres, which validates Torrent-Guasp’s helical myocardial band ventricular anatomical model.
 
  Address Viena, Austria  
  Corporate Author Thesis  
  Publisher Springer Link Place of Publication Editor  
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  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 1869-4101 ISBN Medium  
  Area Expedition Conference  
  Notes IAM Approved no  
  Call Number IAM @ iam @ HPM2012 Serial 1858  
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Author Ferran Poveda; Enric Marti; Debora Gil; Francesc Carreras; Manel Ballester edit   pdf
url  doi
openurl 
  Title Helical Structure of Ventricular Anatomy by Diffusion Tensor Cardiac MR Tractography Type Journal Article
  Year 2012 Publication Journal of American College of Cardiology Abbreviated Journal JACC  
  Volume 5 Issue 7 Pages 754-755  
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  Abstract It is widely accepted that myocardial fiber architecture plays a critical role in myocardial contractility and relaxation (1). However, there is a lack of consensus about the distribution of the myocardial fibers and their spatial arrangement in the left and right ventricles. An understanding of the cardiac architecture should benefit the ventricular functional assessment, left ventricular reconstructive surgery planning, or resynchronization therapy in heart failure. Researchers have proposed several conceptual models to describe the architecture of the heart, ranging from gross dissection to histological presentation. The cardiac mesh model (2) proposes that the myocytes are arranged longitudinally and radially change their angulation along the myocardial depth. By contrast, the helical ventricular myocardial model states that the ventricular myocardium is a continuous anatomical helical layout of myocardial fibers (1  
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  ISSN 1936-878X ISBN Medium  
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  Notes IAM Approved no  
  Call Number IAM @ iam @ PMG2012 Serial 1985  
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Author David Roche; Debora Gil; Jesus Giraldo edit  url
doi  openurl
  Title Multiple active receptor conformation, agonist efficacy and maximum effect of the system: the conformation-based operational model of agonism, Type Journal Article
  Year 2013 Publication Drug Discovery Today Abbreviated Journal DDT  
  Volume 18 Issue 7-8 Pages 365-371  
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  Abstract The operational model of agonism assumes that the maximum effect a particular receptor system can achieve (the Em parameter) is fixed. Em estimates are above but close to the asymptotic maximum effects of endogenous agonists. The concept of Em is contradicted by superagonists and those positive allosteric modulators that significantly increase the maximum effect of endogenous agonists. An extension of the operational model is proposed that assumes that the Em parameter does not necessarily have a single value for a receptor system but has multiple values associated to multiple active receptor conformations. The model provides a mechanistic link between active receptor conformation and agonist efficacy, which can be useful for the analysis of agonist response under different receptor scenarios.  
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  Publisher Elsevier Place of Publication Editor  
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  Notes IAM; 600.057; 600.054 Approved no  
  Call Number IAM @ iam @ RGG2013a Serial 2190  
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Author David Roche; Debora Gil; Jesus Giraldo edit  doi
openurl 
  Title Mechanistic analysis of the function of agonists and allosteric modulators: Reconciling two-state and operational models Type Journal Article
  Year 2013 Publication British Journal of Pharmacology Abbreviated Journal BJP  
  Volume 169 Issue 6 Pages 1189-202  
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  Abstract Two-state and operational models of both agonism and allosterism are compared to identify and characterize common pharmacological parameters. To account for the receptor-dependent basal response, constitutive receptor activity is considered in the operational models. By arranging two-state models as the fraction of active receptors and operational models as the fractional response relative to the maximum effect of the system, a one-by-one correspondence between parameters is found. The comparative analysis allows a better understanding of complex allosteric interactions. In particular, the inclusion of constitutive receptor activity in the operational model of allosterism allows the characterization of modulators able to lower the basal response of the system; that is, allosteric modulators with negative intrinsic efficacy. Theoretical simulations and overall goodness of fit of the models to simulated data suggest that it is feasible to apply the models to experimental data and constitute one step forward in receptor theory formalism.  
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  Notes IAM; 600.044; 605.203 Approved no  
  Call Number IAM @ iam @ RGG2013b Serial 2195  
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Author Enric Marti; J.Roncaries; Debora Gil; Aura Hernandez-Sabate; Antoni Gurgui; Ferran Poveda edit  doi
openurl 
  Title PBL On Line: A proposal for the organization, part-time monitoring and assessment of PBL group activities Type Journal
  Year 2015 Publication Journal of Technology and Science Education Abbreviated Journal JOTSE  
  Volume 5 Issue 2 Pages 87-96  
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  Notes IAM; ADAS; 600.076; 600.075 Approved no  
  Call Number Admin @ si @ MRG2015 Serial 2608  
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Author Carles Sanchez; Oriol Ramos Terrades; Patricia Marquez; Enric Marti; J.Roncaries; Debora Gil edit  doi
openurl 
  Title Automatic evaluation of practices in Moodle for Self Learning in Engineering Type Journal
  Year 2015 Publication Journal of Technology and Science Education Abbreviated Journal JOTSE  
  Volume 5 Issue 2 Pages 97-106  
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  Notes IAM; DAG; 600.075; 600.077 Approved no  
  Call Number Admin @ si @ SRM2015 Serial 2610  
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Author Carles Sanchez; Jorge Bernal; F. Javier Sanchez; Antoni Rosell; Marta Diez-Ferrer; Debora Gil edit   pdf
doi  openurl
  Title Towards On-line Quantification of Tracheal Stenosis from Videobronchoscopy Type Journal Article
  Year 2015 Publication International Journal of Computer Assisted Radiology and Surgery Abbreviated Journal IJCAR  
  Volume 10 Issue 6 Pages 935-945  
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  Notes IAM; MV; 600.075 Approved no  
  Call Number Admin @ si @ SBS2015a Serial 2611  
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Author H.Martin Kjer; Jens Fagertuna; Sergio Vera; Debora Gil; Miguel Angel Gonzalez Ballester; Rasmus R. Paulsena edit   pdf
url  openurl
  Title Free-form image registration of human cochlear uCT data using skeleton similarity as anatomical prior Type Journal Article
  Year 2016 Publication Patter Recognition Letters Abbreviated Journal PRL  
  Volume 76 Issue 1 Pages 76-82  
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  Notes IAM; 600.060 Approved no  
  Call Number Admin @ si @ MFV2017b Serial 2941  
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Author Marta Diez-Ferrer; Debora Gil; Elena Carreño; Susana Padrones; Samantha Aso; Vanesa Vicens; Noelia Cubero de Frutos; Rosa Lopez Lisbona; Carles Sanchez; Agnes Borras; Antoni Rosell edit   pdf
url  openurl
  Title Positive Airway Pressure-Enhanced CT to Improve Virtual Bronchoscopic Navigation Type Journal Article
  Year 2017 Publication European Respiratory Journal Abbreviated Journal ERJ  
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  Notes IAM Approved no  
  Call Number Admin @ si @ DGC2017b Serial 3632  
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