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Author |
Juan Borrego-Carazo; Carles Sanchez; David Castells; Jordi Carrabina; Debora Gil |
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Title |
BronchoPose: an analysis of data and model configuration for vision-based bronchoscopy pose estimation |
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Journal Article |
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2023 |
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Computer Methods and Programs in Biomedicine |
Abbreviated Journal |
CMPB |
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228 |
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107241 |
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Videobronchoscopy guiding; Deep learning; Architecture optimization; Datasets; Standardized evaluation framework; Pose estimation |
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Abstract |
Vision-based bronchoscopy (VB) models require the registration of the virtual lung model with the frames from the video bronchoscopy to provide effective guidance during the biopsy. The registration can be achieved by either tracking the position and orientation of the bronchoscopy camera or by calibrating its deviation from the pose (position and orientation) simulated in the virtual lung model. Recent advances in neural networks and temporal image processing have provided new opportunities for guided bronchoscopy. However, such progress has been hindered by the lack of comparative experimental conditions.
In the present paper, we share a novel synthetic dataset allowing for a fair comparison of methods. Moreover, this paper investigates several neural network architectures for the learning of temporal information at different levels of subject personalization. In order to improve orientation measurement, we also present a standardized comparison framework and a novel metric for camera orientation learning. Results on the dataset show that the proposed metric and architectures, as well as the standardized conditions, provide notable improvements to current state-of-the-art camera pose estimation in video bronchoscopy. |
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Elsevier |
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IAM; |
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Admin @ si @ BSC2023 |
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3702 |
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Author |
Oriol Ramos Terrades; Albert Berenguel; Debora Gil |
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Title |
A Flexible Outlier Detector Based on a Topology Given by Graph Communities |
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Journal Article |
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Year |
2022 |
Publication |
Big Data Research |
Abbreviated Journal |
BDR |
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29 |
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100332 |
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Classification algorithms; Detection algorithms; Description of feature space local structure; Graph communities; Machine learning algorithms; Outlier detectors |
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Outlier detection is essential for optimal performance of machine learning methods and statistical predictive models. Their detection is especially determinant in small sample size unbalanced problems, since in such settings outliers become highly influential and significantly bias models. This particular experimental settings are usual in medical applications, like diagnosis of rare pathologies, outcome of experimental personalized treatments or pandemic emergencies. In contrast to population-based methods, neighborhood based local approaches compute an outlier score from the neighbors of each sample, are simple flexible methods that have the potential to perform well in small sample size unbalanced problems. A main concern of local approaches is the impact that the computation of each sample neighborhood has on the method performance. Most approaches use a distance in the feature space to define a single neighborhood that requires careful selection of several parameters, like the number of neighbors.
This work presents a local approach based on a local measure of the heterogeneity of sample labels in the feature space considered as a topological manifold. Topology is computed using the communities of a weighted graph codifying mutual nearest neighbors in the feature space. This way, we provide with a set of multiple neighborhoods able to describe the structure of complex spaces without parameter fine tuning. The extensive experiments on real-world and synthetic data sets show that our approach outperforms, both, local and global strategies in multi and single view settings. |
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August 28, 2022 |
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DAG; IAM; 600.140; 600.121; 600.139; 600.145; 600.159 |
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Admin @ si @ RBG2022a |
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3718 |
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Debora Gil; Ruth Aris; Agnes Borras; Esmitt Ramirez; Rafael Sebastian; Mariano Vazquez |
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Title |
Influence of fiber connectivity in simulations of cardiac biomechanics |
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Year |
2019 |
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International Journal of Computer Assisted Radiology and Surgery |
Abbreviated Journal |
IJCAR |
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14 |
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1 |
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63–72 |
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Cardiac electromechanical simulations; Diffusion tensor imaging; Fiber connectivity |
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PURPOSE:
Personalized computational simulations of the heart could open up new improved approaches to diagnosis and surgery assistance systems. While it is fully recognized that myocardial fiber orientation is central for the construction of realistic computational models of cardiac electromechanics, the role of its overall architecture and connectivity remains unclear. Morphological studies show that the distribution of cardiac muscular fibers at the basal ring connects epicardium and endocardium. However, computational models simplify their distribution and disregard the basal loop. This work explores the influence in computational simulations of fiber distribution at different short-axis cuts.
METHODS:
We have used a highly parallelized computational solver to test different fiber models of ventricular muscular connectivity. We have considered two rule-based mathematical models and an own-designed method preserving basal connectivity as observed in experimental data. Simulated cardiac functional scores (rotation, torsion and longitudinal shortening) were compared to experimental healthy ranges using generalized models (rotation) and Mahalanobis distances (shortening, torsion).
RESULTS:
The probability of rotation was significantly lower for ruled-based models [95% CI (0.13, 0.20)] in comparison with experimental data [95% CI (0.23, 0.31)]. The Mahalanobis distance for experimental data was in the edge of the region enclosing 99% of the healthy population.
CONCLUSIONS:
Cardiac electromechanical simulations of the heart with fibers extracted from experimental data produce functional scores closer to healthy ranges than rule-based models disregarding architecture connectivity. |
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IAM; 600.096; 601.323; 600.139; 600.145 |
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Admin @ si @ GAB2019a |
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3133 |
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Author |
Carles Sanchez; Jorge Bernal; F. Javier Sanchez; Antoni Rosell; Marta Diez-Ferrer; Debora Gil |
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Title |
Towards On-line Quantification of Tracheal Stenosis from Videobronchoscopy |
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Journal Article |
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2015 |
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International Journal of Computer Assisted Radiology and Surgery |
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IJCAR |
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10 |
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6 |
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935-945 |
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IAM; MV; 600.075 |
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Admin @ si @ SBS2015a |
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2611 |
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Author |
Debora Gil; David Roche; Agnes Borras; Jesus Giraldo |
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Title |
Terminating Evolutionary Algorithms at their Steady State |
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Journal Article |
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Year |
2015 |
Publication |
Computational Optimization and Applications |
Abbreviated Journal |
COA |
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61 |
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2 |
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489-515 |
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Evolutionary algorithms; Termination condition; Steady state; Differential evolution |
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Assessing the reliability of termination conditions for evolutionary algorithms (EAs) is of prime importance. An erroneous or weak stop criterion can negatively affect both the computational effort and the final result. We introduce a statistical framework for assessing whether a termination condition is able to stop an EA at its steady state, so that its results can not be improved anymore. We use a regression model in order to determine the requirements ensuring that a measure derived from EA evolving population is related to the distance to the optimum in decision variable space. Our framework is analyzed across 24 benchmark test functions and two standard termination criteria based on function fitness value in objective function space and EA population decision variable space distribution for the differential evolution (DE) paradigm. Results validate our framework as a powerful tool for determining the capability of a measure for terminating EA and the results also identify the decision variable space distribution as the best-suited for accurately terminating DE in real-world applications. |
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Springer US |
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0926-6003 |
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IAM; 600.044; 605.203; 600.060; 600.075 |
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Admin @ si @ GRB2015 |
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2560 |
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Mireia Sole; Joan Blanco; Debora Gil; Oliver Valero; B. Cardenas; G. Fonseka; E. Anton; Alvaro Pascual; Richard Frodsham; Zaida Sarrate |
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Time to match; when do homologous chromosomes become closer? |
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2022 |
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Chromosoma |
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CHRO |
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In most eukaryotes, pairing of homologous chromosomes is an essential feature of meiosis that ensures homologous recombination and segregation. However, when the pairing process begins, it is still under investigation. Contrasting data exists in Mus musculus, since both leptotene DSB-dependent and preleptotene DSB-independent mechanisms have been described. To unravel this contention, we examined homologous pairing in pre-meiotic and meiotic Mus musculus cells using a threedimensional fuorescence in situ hybridization-based protocol, which enables the analysis of the entire karyotype using DNA painting probes. Our data establishes in an unambiguously manner that 73.83% of homologous chromosomes are already paired at premeiotic stages (spermatogonia-early preleptotene spermatocytes). The percentage of paired homologous chromosomes increases to 84.60% at mid-preleptotene-zygotene stage, reaching 100% at pachytene stage. Importantly, our results demonstrate a high percentage of homologous pairing observed before the onset of meiosis; this pairing does not occur randomly, as the percentage was higher than that observed in somatic cells (19.47%) and between nonhomologous chromosomes (41.1%). Finally, we have also observed that premeiotic homologous pairing is asynchronous and independent of the chromosome size, GC content, or presence of NOR regions. |
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August, 2022 |
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IAM; 601.139; 600.145; 600.096 |
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Admin @ si @ SBG2022 |
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3719 |
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Author |
Ole Larsen; Petia Radeva; Enric Marti |
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Title |
Bounds on the optimal elasticity parameters for a snake |
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1995 |
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Image Analysis and Processing |
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37-42 |
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This paper develops a formalism by which an estimate for the upper and lower bounds for the elasticity parameters for a snake can be obtained. Objects different in size and shape give rise to different bounds. The bounds can be obtained based on an analysis of the shape of the object of interest. Experiments on synthetic images show a good correlation between the estimated behaviour of the snake and the one actually observed. Experiments on real X-ray images show that the parameters for optimal segmentation lie within the estimated bounds. |
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MILAB;IAM |
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IAM @ iam @ LRM1995a |
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1559 |
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Ernest Valveny; Enric Marti |
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Deformable Template Matching within a Bayesian Framework for Hand-Written Graphic Symbol Recognition |
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2000 |
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Graphics Recognition Recent Advances |
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1941 |
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193-208 |
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We describe a method for hand-drawn symbol recognition based on deformable template matching able to handle uncertainty and imprecision inherent to hand-drawing. Symbols are represented as a set of straight lines and their deformations as geometric transformations of these lines. Matching, however, is done over the original binary image to avoid loss of information during line detection. It is defined as an energy minimization problem, using a Bayesian framework which allows to combine fidelity to ideal shape of the symbol and flexibility to modify the symbol in order to get the best fit to the binary input image. Prior to matching, we find the best global transformation of the symbol to start the recognition process, based on the distance between symbol lines and image lines. We have applied this method to the recognition of dimensions and symbols in architectural floor plans and we show its flexibility to recognize distorted symbols. |
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Springer Verlag |
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Springer Verlag |
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IAM @ iam @ MVA2000 |
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1655 |
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Oriol Rodriguez-Leor; J. Mauri; Eduard Fernandez-Nofrerias; M. Gomez; Antonio Tovar; L. Cano; C. Diego; Carme Julia; Vicente del Valle; Debora Gil; Petia Radeva |
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Ecografia Intracoronaria: Segmentacio Automatica de area de la llum |
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2002 |
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Revista Societat Catalana de Cardiologia |
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42 |
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Barcelona |
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XIVe Congres de la Societat Catalana de Cardiologia |
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MILAB;IAM |
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BCNPCL @ bcnpcl @ RMF2002 |
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435 |
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Oriol Rodriguez-Leor; J. Mauri; Eduard Fernandez-Nofrerias; Antonio Tovar; Vicente del Valle; Aura Hernandez-Sabate; Debora Gil; Petia Radeva |
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Utilizacion de la estructura de los campos vectoriales para la deteccion de la Adventicia en imagenes de Ecografia Intracoronaria |
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2004 |
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Revista Española de Cardiología |
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REC |
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57 |
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100 |
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BCNPCL @ bcnpcl @ RMF2004 |
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