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Author |
Josep Llados;Horst Bunke; Enric Marti |
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Title |
Using Cyclic String Matching to Find Rotational and Reflectional Symmetries in Shapes |
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Conference Article |
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1997 |
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Intelligent Robots: Sensing, Modeling and Planning |
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164-179 |
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Dagstuhl Workshop |
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World Scientific Press |
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9810231857 |
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DAG;IAM; |
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IAM @ iam @ LBM1997b |
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1563 |
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Author |
Enric Marti; Jordi Regincos; Juan Jose Villanueva; Jaime Lopez-Krahe |
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Title |
Line drawing interpretation as polyhedral objects to man-machine interaction in CAD systems |
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Book Chapter |
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1994 |
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Advances in Pattern Recognition and Image Analysis, |
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158-169 |
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World Scientific Pub. |
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981-02-1872-9 |
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IAM;ISE |
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IAM @ iam @ MRL1994 |
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1609 |
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Author |
Debora Gil; Jaume Garcia; Mariano Vazquez; Ruth Aris; Guilleaume Houzeaux |
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Title |
Patient-Sensitive Anatomic and Functional 3D Model of the Left Ventricle Function |
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Conference Article |
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Year |
2008 |
Publication |
8th World Congress on Computational Mechanichs (WCCM8) |
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Left Ventricle, Electromechanical Models, Image Processing, Magnetic Resonance. |
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Early diagnosis and accurate treatment of Left Ventricle (LV) dysfunction significantly increases the patient survival. Impairment of LV contractility due to cardiovascular diseases is reflected in its motion patterns. Recent advances in medical imaging, such as Magnetic Resonance (MR), have encouraged research on 3D simulation and modelling of the LV dynamics. Most of the existing 3D models [1] consider just the gross anatomy of the LV and restore a truncated ellipse which deforms along the cardiac cycle. The contraction mechanics of any muscle strongly depends on the spatial orientation of its muscular fibers since the motion that the muscle undergoes mainly takes place along the fibers. It follows that such simplified models do not allow evaluation of the heart electro-mechanical function and coupling, which has recently risen as the key point for understanding the LV functionality [2]. In order to thoroughly understand the LV mechanics it is necessary to consider the complete anatomy of the LV given by the orientation of the myocardial fibres in 3D space as described by Torrent Guasp [3].
We propose developing a 3D patient-sensitive model of the LV integrating, for the first time, the ven- tricular band anatomy (fibers orientation), the LV gross anatomy and its functionality. Such model will represent the LV function as a natural consequence of its own ventricular band anatomy. This might be decisive in restoring a proper LV contraction in patients undergoing pace marker treatment.
The LV function is defined as soon as the propagation of the contractile electromechanical pulse has been modelled. In our experiments we have used the wave equation for the propagation of the electric pulse. The electromechanical wave moves on the myocardial surface and should have a conductivity tensor oriented along the muscular fibers. Thus, whatever mathematical model for electric pulse propa- gation [4] we consider, the complete anatomy of the LV should be extracted.
The LV gross anatomy is obtained by processing multi slice MR images recorded for each patient. Information about the myocardial fibers distribution can only be extracted by Diffusion Tensor Imag- ing (DTI), which can not provide in vivo information for each patient. As a first approach, we have
Figure 1: Scheme for the Left Ventricle Patient-Sensitive Model.
computed an average model of fibers from several DTI studies of canine hearts. This rough anatomy is the input for our electro-mechanical propagation model simulating LV dynamics. The average fiber orientation is updated until the simulated LV motion agrees with the experimental evidence provided by the LV motion observed in tagged MR (TMR) sequences. Experimental LV motion is recovered by applying image processing, differential geometry and interpolation techniques to 2D TMR slices [5]. The pipeline in figure 1 outlines the interaction between simulations and experimental data leading to our patient-tailored model. |
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Venice; Italy |
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9788496736559 |
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IAM; |
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IAM @ iam @ GGV2008b |
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993 |
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Author |
Carles Sanchez; Debora Gil; Antoni Rosell; Albert Andaluz; F. Javier Sanchez |
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Title |
Segmentation of Tracheal Rings in Videobronchoscopy combining Geometry and Appearance |
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Conference Article |
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Year |
2013 |
Publication |
Proceedings of the International Conference on Computer Vision Theory and Applications |
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1 |
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153--161 |
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Video-bronchoscopy, tracheal ring segmentation, trachea geometric and appearance model |
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Videobronchoscopy is a medical imaging technique that allows interactive navigation inside the respiratory pathways and minimal invasive interventions. Tracheal procedures are ordinary interventions that require measurement of the percentage of obstructed pathway for injury (stenosis) assessment. Visual assessment of stenosis in videobronchoscopic sequences requires high expertise of trachea anatomy and is prone to human error. Accurate detection of tracheal rings is the basis for automated estimation of the size of stenosed trachea. Processing of videobronchoscopic images acquired at the operating room is a challenging task due to the wide range of artifacts and acquisition conditions. We present a model of the geometric-appearance of tracheal rings for its detection in videobronchoscopic videos. Experiments on sequences acquired at the operating room, show a performance close to inter-observer variability |
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Barcelona; February 2013 |
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SciTePress |
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Portugal |
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Sebastiano Battiato and José Braz |
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LNCS |
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978-989-8565-47-1 |
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800 |
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VISAPP |
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IAM;MV; 600.044; 600.047; 600.060; 605.203 |
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IAM @ iam @ SGR2013 |
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2123 |
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Author |
Antoni Gurgui; Debora Gil; Enric Marti |
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Title |
Laplacian Unitary Domain for Texture Morphing |
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Conference Article |
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2015 |
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Proceedings of the 10th International Conference on Computer Vision Theory and Applications VISIGRAPP2015 |
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1 |
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693-699 |
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Facial; metamorphosis;LaplacianMorphing |
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Deformation of expressive textures is the gateway to realistic computer synthesis of expressions. By their good mathematical properties and flexible formulation on irregular meshes, most texture mappings rely on solutions to the Laplacian in the cartesian space. In the context of facial expression morphing, this approximation can be seen from the opposite point of view by neglecting the metric. In this paper, we use the properties of the Laplacian in manifolds to present a novel approach to warping expressive facial images in order to generate a morphing between them. |
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Munich; Germany; February 2015 |
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SciTePress |
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978-989-758-089-5 |
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VISAPP |
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IAM; 600.075 |
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Admin @ si @ GGM2015 |
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2614 |
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Author |
Aura Hernandez-Sabate; Debora Gil |
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Title |
The Benefits of IVUS Dynamics for Retrieving Stable Models of Arteries |
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Book Chapter |
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Year |
2012 |
Publication |
Intravascular Ultrasound |
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185-206 |
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Intech |
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Editor |
Yasuhiro Honda |
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Language |
English |
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english |
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978-953-307-900-4 |
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IAM; ADAS |
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IAM @ iam @ HeG2012 |
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1684 |
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Author |
David Roche; Debora Gil; Jesus Giraldo |
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Title |
Mathematical modeling of G protein-coupled receptor function: What can we learn from empirical and mechanistic models? |
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Book Chapter |
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2014 |
Publication |
G Protein-Coupled Receptors – Modeling and Simulation Advances in Experimental Medicine and Biology |
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796 |
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3 |
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159-181 |
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β-arrestin; biased agonism; curve fitting; empirical modeling; evolutionary algorithm; functional selectivity; G protein; GPCR; Hill coefficient; intrinsic efficacy; inverse agonism; mathematical modeling; mechanistic modeling; operational model; parameter optimization; receptor dimer; receptor oligomerization; receptor constitutive activity; signal transduction; two-state model |
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Empirical and mechanistic models differ in their approaches to the analysis of pharmacological effect. Whereas the parameters of the former are not physical constants those of the latter embody the nature, often complex, of biology. Empirical models are exclusively used for curve fitting, merely to characterize the shape of the E/[A] curves. Mechanistic models, on the contrary, enable the examination of mechanistic hypotheses by parameter simulation. Regretfully, the many parameters that mechanistic models may include can represent a great difficulty for curve fitting, representing, thus, a challenge for computational method development. In the present study some empirical and mechanistic models are shown and the connections, which may appear in a number of cases between them, are analyzed from the curves they yield. It may be concluded that systematic and careful curve shape analysis can be extremely useful for the understanding of receptor function, ligand classification and drug discovery, thus providing a common language for the communication between pharmacologists and medicinal chemists. |
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Springer Netherlands |
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0065-2598 |
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978-94-007-7422-3 |
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IAM; 600.075 |
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IAM @ iam @ RGG2014 |
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2197 |
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Author |
Sergio Vera |
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Title |
Anatomic Registration based on Medial Axis Parametrizations |
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Book Whole |
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2015 |
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PhD Thesis, Universitat Autonoma de Barcelona-CVC |
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Image registration has been for many years the gold standard method to bring two images into correspondence. It has been used extensively in the eld of medical imaging in order to put images of dierent patients into a common overlapping spatial position. However, medical image registration is a slow, iterative optimization process, where many variables and prone to fall into the pit traps local minima.
A coordinate system parameterizing the interior of organs is a powerful tool for a systematic localization of injured tissue. If the same coordinate values are assigned to specic anatomical sites, parameterizations ensure integration of data across different medical image modalities. Harmonic mappings have been used to produce parametric meshes over the surface of anatomical shapes, given their ability to set values at specic locations through boundary conditions. However, most of the existing implementations in medical imaging restrict to either anatomical surfaces, or the depth coordinate with boundary conditions is given at discrete sites of limited geometric diversity.
The medial surface of the shape can be used to provide a continuous basis for the denition of a depth coordinate. However, given that dierent methods for generation of medial surfaces generate dierent manifolds, not all of them are equally suited to be the basis of radial coordinate for a parameterization. It would be desirable that the medial surface will be smooth, and robust to surface shape noise, with low number of spurious branches or surfaces.
In this thesis we present methods for computation of smooth medial manifolds and apply them to the generation of for anatomical volumetric parameterization that extends current harmonic parameterizations to the interior anatomy using information provided by the volume medial surface. This reference system sets a solid base for creating anatomical models of the anatomical shapes, and allows comparing several patients in a common framework of reference. |
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November 2015 |
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Thesis |
Ph.D. thesis |
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Publisher |
Ediciones Graficas Rey |
Place of Publication |
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Editor |
Debora Gil;Miguel Angel Gonzalez Ballester |
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978-84-943427-8-3 |
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IAM; 600.075 |
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no |
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Call Number |
Admin @ si @ Ver2015 |
Serial |
2708 |
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Author |
Patricia Marquez |
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Title |
A Confidence Framework for the Assessment of Optical Flow Performance |
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Book Whole |
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Year |
2015 |
Publication |
PhD Thesis, Universitat Autonoma de Barcelona-CVC |
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Optical Flow (OF) is the input of a wide range of decision support systems such as car driver assistance, UAV guiding or medical diagnose. In these real situations, the absence of ground truth forces to assess OF quality using quantities computed from either sequences or the computed optical flow itself. These quantities are generally known as Confidence Measures, CM. Even if we have a proper confidence measure we still need a way to evaluate its ability to discard pixels with an OF prone to have a large error. Current approaches only provide a descriptive evaluation of the CM performance but such approaches are not capable to fairly compare different confidence measures and optical flow algorithms. Thus, it is of prime importance to define a framework and a general road map for the evaluation of optical flow performance.
This thesis provides a framework able to decide which pairs “ optical flow – confidence measure” (OF-CM) are best suited for optical flow error bounding given a confidence level determined by a decision support system. To design this framework we cover the following points:
Descriptive scores. As a first step, we summarize and analyze the sources of inaccuracies in the output of optical flow algorithms. Second, we present several descriptive plots that visually assess CM capabilities for OF error bounding. In addition to the descriptive plots, given a plot representing OF-CM capabilities to bound the error, we provide a numeric score that categorizes the plot according to its decreasing profile, that is, a score assessing CM performance.
Statistical framework. We provide a comparison framework that assesses the best suited OF-CM pair for error bounding that uses a two stage cascade process. First of all we assess the predictive value of the confidence measures by means of a descriptive plot. Then, for a sample of descriptive plots computed over training frames, we obtain a generic curve that will be used for sequences with no ground truth. As a second step, we evaluate the obtained general curve and its capabilities to really reflect the predictive value of a confidence measure using the variability across train frames by means of ANOVA.
The presented framework has shown its potential in the application on clinical decision support systems. In particular, we have analyzed the impact of the different image artifacts such as noise and decay to the output of optical flow in a cardiac diagnose system and we have improved the navigation inside the bronchial tree on bronchoscopy. |
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July 2015 |
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Corporate Author |
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Thesis |
Ph.D. thesis |
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Publisher |
Ediciones Graficas Rey |
Place of Publication |
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Editor |
Debora Gil;Aura Hernandez |
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978-84-943427-2-1 |
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IAM; 600.075 |
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no |
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Call Number |
Admin @ si @ Mar2015 |
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2687 |
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Author |
Carles Sanchez |
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Title |
Tracheal Structure Characterization using Geometric and Appearance Models for Efficient Assessment of Stenosis in Videobronchoscopy |
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Book Whole |
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Year |
2014 |
Publication |
PhD Thesis, Universitat Autonoma de Barcelona-CVC |
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Recent advances in endoscopic devices have increased their use for minimal invasive diagnostic and intervention procedures. Among all endoscopic modalities, bronchoscopy is one of the most frequent with around 261 millions of procedures per year. Although the use of bronchoscopy is spread among clinical facilities it presents some drawbacks, being the visual inspection for the assessment of anatomical measurements the most prevalent of them. In
particular, inaccuracies in the estimation of the degree of stenosis (the percentage of obstructed airway) decreases its diagnostic yield and might lead to erroneous treatments. An objective computation of tracheal stenosis in bronchoscopy videos would constitute a breakthrough for this non-invasive technique and a reduction in treatment cost.
This thesis settles the first steps towards on-line reliable extraction of anatomical information from videobronchoscopy for computation of objective measures. In particular, we focus on the computation of the degree of stenosis, which is obtained by comparing the area delimited by a healthy tracheal ring and the stenosed lumen. Reliable extraction of airway structures in interventional videobronchoscopy is a challenging task. This is mainly due to the large variety of acquisition conditions (positions and illumination), devices (different digitalizations) and in videos acquired at the operating room the unpredicted presence of surgical devices (such as probe ends). This thesis contributes to on-line stenosis assessment in several ways. We
propose a parametric strategy for the extraction of lumen and tracheal rings regions based on the characterization of their geometry and appearance that guide a deformable model. The geometric and appearance characterization is based on a physical model describing the way bronchoscopy images are obtained and includes local and global descriptions. In order to ensure a systematic applicability we present a statistical framework to select the optimal
parameters of our method. Experiments perform on the first public annotated database, show that the performance of our method is comparable to the one provided by clinicians and its computation time allows for a on-line implementation in the operating room. |
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Ph.D. thesis |
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Ediciones Graficas Rey |
Place of Publication |
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Editor |
F. Javier Sanchez;Debora Gil;Jorge Bernal |
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978-84-940902-9-5 |
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IAM; 600.075 |
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Call Number |
Admin @ si @ San2014 |
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2575 |
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