Abstract: Chapter 9

Abstract: This paper presents results from the second Thermal Image Super-Resolution (TISR) challenge organized in the framework of the Perception Beyond the Visible Spectrum (PBVS) 2021 workshop. For this second edition, the same thermal image dataset considered during the first challenge has been used; only mid-resolution (MR) and high-resolution (HR) sets have been considered. The dataset consists of 951 training images and 50 testing images for each resolution. A set of 20 images for each resolution is kept aside for evaluation. The two evaluation methodologies proposed for the first challenge are also considered in this opportunity. The first evaluation task consists of measuring the PSNR and SSIM between the obtained SR image and the corresponding ground truth (i.e., the HR thermal image downsampled by four). The second evaluation also consists of measuring the PSNR and SSIM, but in this case, considers the x2 SR obtained from the given MR thermal image; this evaluation is performed between the SR image with respect to the semi-registered HR image, which has been acquired with another camera. The results outperformed those from the first challenge, thus showing an improvement in both evaluation metrics.

Abstract: This paper proposes a new lightweight network, LiNet, that enhancing technical efficiency in lightweight super resolution and operating approximately like very large and costly networks in terms of number of network parameters and operations. The proposed architecture allows the network to learn more abstract properties by avoiding low-level information via multiple links. LiNet introduces a Compact Dense Module, which contains set of inner and outer blocks, to efficiently extract meaningful information, to better leverage multi-level representations before upsampling stage, and to allow an efficient information and gradient flow within the network. Experiments on benchmark datasets show that the proposed LiNet achieves favorable performance against lightweight state-of-the-art methods.

Abstract: Session-based recommenders, used for making predictions out of users’ uninterrupted sequences of actions, are attractive for many applications. Here, for this task we propose using metric learning, where a common embedding space for sessions and items is created, and distance measures dissimilarity between the provided sequence of users’ events and the next action. We discuss and compare metric learning approaches to commonly used learning-to-rank methods, where some synergies exist. We propose a simple architecture for problem analysis and demonstrate that neither extensively big nor deep architectures are necessary in order to outperform existing methods. The experimental results against strong baselines on four datasets are provided with an ablation study.

Abstract: In class-incremental learning, an agent with limited resources needs to learn a sequence of classification tasks, forming an ever growing classification problem, with the constraint of not being able to access data from previous tasks. The main difference with task-incremental learning, where a task-ID is available at inference time, is that the learner also needs to perform crosstask discrimination, i.e. distinguish between classes that have not been seen together. Approaches to tackle this problem are numerous and mostly make use of an external memory (buffer) of non-negligible size. In this paper, we ablate the learning of crosstask features and study its influence on the performance of basic replay strategies used for class-IL. We also define a new forgetting measure for class-incremental learning, and see that forgetting is not the principal cause of low performance. Our experimental results show that future algorithms for class-incremental learning should not only prevent forgetting, but also aim to improve the quality of the cross-task features. This is especially important when the number of classes per task is small.

Abstract: Background Reliable predictive imaging markers of response to immune checkpoint inhibitors are needed. Purpose To develop and validate a pretreatment CT-based radiomics signature to predict response to immune checkpoint inhibitors in advanced solid tumors. Materials and Methods In this retrospective study, a radiomics signature was developed in patients with advanced solid tumors (including breast, cervix, gastrointestinal) treated with anti-programmed cell death-1 or programmed cell death ligand-1 monotherapy from August 2012 to May 2018 (cohort 1). This was tested in patients with bladder and lung cancer (cohorts 2 and 3). Radiomics variables were extracted from all metastases delineated at pretreatment CT and selected by using an elastic-net model. A regression model combined radiomics and clinical variables with response as the end point. Biologic validation of the radiomics score with RNA profiling of cytotoxic cells (cohort 4) was assessed with Mann-Whitney analysis. Results The radiomics signature was developed in 85 patients (cohort 1: mean age, 58 years ± 13 [standard deviation]; 43 men) and tested on 46 patients (cohort 2: mean age, 70 years ± 12; 37 men) and 47 patients (cohort 3: mean age, 64 years ± 11; 40 men). Biologic validation was performed in a further cohort of 20 patients (cohort 4: mean age, 60 years ± 13; 14 men). The radiomics signature was associated with clinical response to immune checkpoint inhibitors (area under the curve [AUC], 0.70; 95% CI: 0.64, 0.77; P < .001). In cohorts 2 and 3, the AUC was 0.67 (95% CI: 0.58, 0.76) and 0.67 (95% CI: 0.56, 0.77; P < .001), respectively. A radiomics-clinical signature (including baseline albumin level and lymphocyte count) improved on radiomics-only performance (AUC, 0.74 [95% CI: 0.63, 0.84; P < .001]; Akaike information criterion, 107.00 and 109.90, respectively). Conclusion A pretreatment CT-based radiomics signature is associated with response to immune checkpoint inhibitors, likely reflecting the tumor immunophenotype. © RSNA, 2021 Online supplemental material is available for this article. See also the editorial by Summers in this issue.