Abstract: Gliomas are the most common primary brain malignancies, with different degrees of aggressiveness, variable prognosis and various heterogeneous histologic sub-regions, i.e., peritumoral edematous/invaded tissue, necrotic core, active and non-enhancing core. This intrinsic heterogeneity is also portrayed in their radio-phenotype, as their sub-regions are depicted by varying intensity profiles disseminated across multiparametric magnetic resonance imaging (mpMRI) scans, reflecting varying biological properties. Their heterogeneous shape, extent, and location are some of the factors that make these tumors difficult to resect, and in some cases inoperable. The amount of resected tumor is a factor also considered in longitudinal scans, when evaluating the apparent tumor for potential diagnosis of progression. Furthermore, there is mounting evidence that accurate segmentation of the various tumor sub-regions can offer the basis for quantitative image analysis towards prediction of patient overall survival. This study assesses the state-of-the-art machine learning (ML) methods used for brain tumor image analysis in mpMRI scans, during the last seven instances of the International Brain Tumor Segmentation (BraTS) challenge, i.e. 2012-2018. Specifically, we focus on i) evaluating segmentations of the various glioma sub-regions in preoperative mpMRI scans, ii) assessing potential tumor progression by virtue of longitudinal growth of tumor sub-regions, beyond use of the RECIST criteria, and iii) predicting the overall survival from pre-operative mpMRI scans of patients that undergone gross total resection. Finally, we investigate the challenge of identifying the best ML algorithms for each of these tasks, considering that apart from being diverse on each instance of the challenge, the multi-institutional mpMRI BraTS dataset has also been a continuously evolving/growing dataset.

Abstract: CoRR abs/1905.04107
The availability and use of egocentric data are rapidly increasing due to the growing use of wearable cameras. Our aim is to study the effect (positive, neutral or negative) of egocentric images or events on an observer. Given egocentric photostreams capturing the wearer's days, we propose a method that aims to assign sentiment to events extracted from egocentric photostreams. Such moments can be candidates to retrieve according to their possibility of representing a positive experience for the camera's wearer. The proposed approach obtained a classification accuracy of 75% on the test set, with a deviation of 8%. Our model makes a step forward opening the door to sentiment recognition in egocentric photostreams.

Abstract: CoRR abs/1907.00856
Skin lesion segmentation in dermoscopic images is a challenge due to their blurry and irregular boundaries. Most of the segmentation approaches based on deep learning are time and memory consuming due to the hundreds of millions of parameters. Consequently, it is difficult to apply them to real dermatoscope devices with limited GPU and memory resources. In this paper, we propose a lightweight and efficient Generative Adversarial Networks (GAN) model, called MobileGAN for skin lesion segmentation. More precisely, the MobileGAN combines 1D non-bottleneck factorization networks with position and channel attention modules in a GAN model. The proposed model is evaluated on the test dataset of the ISBI 2017 challenges and the validation dataset of ISIC 2018 challenges. Although the proposed network has only 2.35 millions of parameters, it is still comparable with the state-of-the-art. The experimental results show that our MobileGAN obtains comparable performance with an accuracy of 97.61%.

Abstract: Outlier, or anomaly, detection is essential for optimal performance of machine learning methods and statistical predictive models. It is not just a technical step in a data cleaning process but a key topic in many fields such as fraudulent document detection, in medical applications and assisted diagnosis systems or detecting security threats. In contrast to population-based methods, neighborhood based local approaches are simple flexible methods that have the potential to perform well in small sample size unbalanced problems. However, a main concern of local approaches is the impact that the computation of each sample neighborhood has on the method performance. Most approaches use a distance in the feature space to define a single neighborhood that requires careful selection of several parameters. This work presents a local approach based on a local measure of the heterogeneity of sample labels in the feature space considered as a topological manifold. Topology is computed using the communities of a weighted graph codifying mutual nearest neighbors in the feature space. This way, we provide with a set of multiple neighborhoods able to describe the structure of complex spaces without parameter fine tuning. The extensive experiments on real-world data sets show that our approach overall outperforms, both, local and global strategies in multi and single view settings.

Abstract: CoRR abs/2006.02570
The outbreak of COVID-19 has shocked the entire world with its fairly rapid spread and has challenged different sectors. One of the most effective ways to limit its spread is the early and accurate diagnosis of infected patients. Medical imaging such as X-ray and Computed Tomography (CT) combined with the potential of Artificial Intelligence (AI) plays an essential role in supporting the medical staff in the diagnosis process. Thereby, the use of five different deep learning models (ResNet18, ResNet34, InceptionV3, InceptionResNetV2, and DenseNet161) and their Ensemble have been used in this paper, to classify COVID-19, pneumoniæ and healthy subjects using Chest X-Ray. Multi-label classification was performed to predict multiple pathologies for each patient, if present. Foremost, the interpretability of each of the networks was thoroughly studied using techniques like occlusion, saliency, input X gradient, guided backpropagation, integrated gradients, and DeepLIFT. The mean Micro-F1 score of the models for COVID-19 classifications ranges from 0.66 to 0.875, and is 0.89 for the Ensemble of the network models. The qualitative results depicted the ResNets to be the most interpretable model.

Abstract: arXiv:2010.12427
Unsupervised domain adaptation (UDA) aims to transfer the knowledge learned from a labeled source domain to an unlabeled target domain. Existing UDA methods require access to source data during adaptation, which may not be feasible in some real-world applications. In this paper, we address the source-free unsupervised domain adaptation (SFUDA) problem, where only the source model is available during the adaptation. We propose a method named BAIT to address SFUDA. Specifically, given only the source model, with the source classifier head fixed, we introduce a new learnable classifier. When adapting to the target domain, class prototypes of the new added classifier will act as a bait. They will first approach the target features which deviate from prototypes of the source classifier due to domain shift. Then those target features are pulled towards the corresponding prototypes of the source classifier, thus achieving feature alignment with the source classifier in the absence of source data. Experimental results show that the proposed method achieves state-of-the-art performance on several benchmark datasets compared with existing UDA and SFUDA methods.

Abstract: arXiv:2001.08311
Recent advances in unsupervised domain adaptation have shown the effectiveness of adversarial training to adapt features across domains, endowing neural networks with the capability of being tested on a target domain without requiring any training annotations in this domain. The great majority of existing domain adaptation models rely on image translation networks, which often contain a huge amount of domain-specific parameters. Additionally, the feature adaptation step often happens globally, at a coarse level, hindering its applicability to tasks such as semantic segmentation, where details are of crucial importance to provide sharp results. In this thesis, we present a novel architecture, which learns to adapt features across domains by taking into account per class information. To that aim, we design a conditional pixel-wise discriminator network, whose output is conditioned on the segmentation masks. Moreover, following recent advances in image translation, we adopt the recently introduced StarGAN architecture as image translation backbone, since it is able to perform translations across multiple domains by means of a single generator network. Preliminary results on a segmentation task designed to assess the effectiveness of the proposed approach highlight the potential of the model, improving upon strong baselines and alternative designs.