Abstract: In this thesis we tackle the problem of automatic characterization of human coronary vessel in Intravascular Ultrasound (IVUS) image modality. The basis for the whole characterization process is machine learning applied to multi-class problems. In all the presented approaches, the Error-Correcting Output Codes (ECOC) framework is used as central element for the design of multi-class classifiers.
Two main topics are tackled in this thesis. First, the automatic detection of the vessel borders is presented. For this purpose, a novel context-aware classifier for multi-class classification of the vessel morphology is presented, namely ECOC-DRF. Based on ECOC-DRF, the lumen border and the media-adventitia border in IVUS are robustly detected by means of a novel holistic approach, achieving an error comparable with inter-observer variability and with state of the art methods.
The two vessel borders define the atheroma area of the vessel. In this area, tissue characterization is required. For this purpose, we present a framework for automatic plaque characterization by processing both texture in IVUS images and spectral information in raw Radio Frequency data. Furthermore, a novel method for fusing in-vivo and in-vitro IVUS data for plaque characterization is presented, namely pSFFS. The method demonstrates to effectively fuse data generating a classifier that improves the tissue characterization in both in-vitro and in-vivo datasets.
A novel method for automatic video summarization in IVUS sequences is also presented. The method aims to detect the key frames of the sequence, i.e., the frames representative of morphological changes. This novel method represents the basis for video summarization in IVUS as well as the markers for the partition of the vessel into morphological and clinically interesting events.
Finally, multi-class learning based on ECOC is applied to lung tissue characterization in Computed Tomography. The novel proposed approach, based on supervised and unsupervised learning, achieves accurate tissue classification on a large and heterogeneous dataset.

Abstract: 3D geometric information is essential for on-board perception in autonomous driving and driver assistance. Autonomous vehicles (AVs) are equipped with calibrated sensor suites. As part of these suites, we can find LiDARs, which are expensive active sensors in charge of providing the 3D geometric information. Depending on the operational conditions for the AV, calibrated stereo rigs may be also sufficient for obtaining 3D geometric information, being these rigs less expensive and easier to install than LiDARs. However, ensuring a proper maintenance and calibration of these types of sensors is not trivial. Accordingly, there is an increasing interest on performing monocular depth estimation (MDE) to obtain 3D geometric information on-board. MDE is very appealing since it allows for appearance and depth being on direct pixelwise correspondence without further calibration. Moreover, a set of single cameras with MDE capabilities would still be a cheap solution for on-board perception, relatively easy to integrate and maintain in an AV.
Best MDE models are based on Convolutional Neural Networks (CNNs) trained in a supervised manner, i.e., assuming pixelwise ground truth (GT). Accordingly, the overall goal of this PhD is to study methods for improving CNN-based MDE accuracy under different training settings. More specifically, this PhD addresses different research questions that are described below. When we started to work in this PhD, state-of-theart methods for MDE were already based on CNNs. In fact, a promising line of work consisted in using image-based semantic supervision (i.e., pixel-level class labels) while training CNNs for MDE using LiDAR-based supervision (i.e., depth). It was common practice to assume that the same raw training data are complemented by both types of supervision, i.e., with depth and semantic labels. However, in practice, it was more common to find heterogeneous datasets with either only depth supervision or only semantic supervision. Therefore, our first work was to research if we could train CNNs for MDE by leveraging depth and semantic information from heterogeneous datasets. We show that this is indeed possible, and we surpassed the state-of-the-art results on MDE at the time we did this research. To achieve our results, we proposed a particular CNN architecture and a new training protocol.
After this research, it was clear that the upper-bound setting to train CNN-based MDE models consists in using LiDAR data as supervision. However, it would be cheaper and more scalable if we would be able to train such models from monocular sequences. Obviously, this is far more challenging, but worth to research. Training MDE models using monocular sequences is possible by relying on structure-from-motion (SfM) principles to generate self-supervision. Nevertheless, problems of camouflaged objects, visibility changes, static-camera intervals, textureless areas, and scale ambiguity, diminish the usefulness of such self-supervision. To alleviate these problems, we perform MDE by virtual-world supervision and real-world SfM self-supervision. We call our proposalMonoDEVSNet. We compensate the SfM self-supervision limitations by leveraging
virtual-world images with accurate semantic and depth supervision, as well as addressing the virtual-to-real domain gap. MonoDEVSNet outperformed previous MDE CNNs trained on monocular and even stereo sequences. We have publicly released MonoDEVSNet at <https://github.com/HMRC-AEL/MonoDEVSNet>.
Finally, since MDE is performed to produce 3D information for being used in downstream tasks related to on-board perception. We also address the question of whether the standard metrics for MDE assessment are a good indicator for future MDE-based driving-related perception tasks. By using 3D object detection on point clouds as proxy of on-board perception, we conclude that, indeed, MDE evaluation metrics give rise to a ranking of methods which reflects relatively well the 3D object detection results we may expect.

Abstract: Image values are the result of a combination of visual information coming from multiple sources. Recovering information from the multiple factors thatproduced an image seems a hard and ill-posed problem. However, it is important to observe that humans develop the ability to interpret images and recognize and isolate specific physical properties of the scene.
Images describing a single physical characteristic of an scene are called intrinsic images. These images would benefit most computer vision tasks which are often affected by the multiple complex effects that are usually found in natural images (e.g. cast shadows, specularities, interreflections...).
In this thesis we analyze the problem of intrinsic image estimation from different perspectives, including the theoretical formulation of the problem, the visual cues that can be used to estimate the intrinsic components and the evaluation mechanisms of the problem.

Abstract: Feature matching is a fundamental problem in Computer Vision, having multiple applications such as tracking, image classification and retrieval, shape recognition and stereo fusion. In numerous domains, it is useful to represent the local structure of the matching features to increase the matching accuracy or to make the correspondence invariant to certain transformations (affine, homography, etc. . . ). However, encoding this knowledge requires complicating the model by establishing high-order relationships between the model elements, and therefore increasing the complexity of the optimization problem.
The importance of many-to-many matching is sometimes dismissed in the literature. Most methods are restricted to perform one-to-one matching, and are usually validated on synthetic, or non-realistic datasets. In a real challenging environment, with scale, pose and illumination variations of the object of interest, as well as the presence of occlusions, clutter, and noisy observations, many-to-many matching is necessary to achieve satisfactory results. As a consequence, finding the most likely many-to-many correspondence often involves a challenging combinatorial optimization process.
In this work, we design and demonstrate matching algorithms that compute many-to-many correspondences, applied to several challenging problems. Our goal is to make use of high-order representations to improve the expressive power of the matching, at the same time that we make feasible the process of inference or optimization of such models. We effectively use graphical models as our preferred representation because they provide an elegant probabilistic framework to tackle structured prediction problems.
We introduce a matching-based tracking algorithm which performs matching between frames of a video sequence in order to solve the difficult problem of headlight tracking at night-time. We also generalise this algorithm to solve the problem of data association applied to various tracking scenarios. We demonstrate the effectiveness of such approach in real video sequences and we show that our tracking algorithm can be used to improve the accuracy of a headlight classification system.
In the second part of this work, we move from single (point) matching to dense (region) matching and we introduce a new hierarchical image representation. We make use of such model to develop a high-order many-to-many matching between pairs of images. We show that the use of high-order models in comparison to simpler models improves not only the accuracy of the results, but also the convergence speed of the inference algorithm.
Finally, we keep exploiting the idea of region matching to design a fully unsupervised image co-segmentation algorithm that is able to perform competitively with state-of-the-art supervised methods. Our method also overcomes the typical drawbacks of some of the past works, such as avoiding the necessity of variate appearances on the image backgrounds. The region matching in this case is applied to effectively exploit inter-image information. We also extend this work to perform co-segmentation of videos, being the first time that such problem is addressed, as a way to perform video object segmentation

Abstract: Over the last few years, the number of consumer computer vision applications has increased dramatically. Today, computer vision solutions can be found in video game consoles, smartphone applications, driving assistance – just to name a few. Ideally, we require the performance of those applications, particularly those that are safety critical to remain constant under any external environment factors, such as changes in illumination or weather conditions. However, this is not always possible or very difficult to obtain by only using visible imagery, due to the inherent limitations of the images from that spectral band. For that reason, the use of images from different or multiple spectral bands is becoming more appealing.
The aforementioned possible advantages of using images from multiples spectral bands on various vision applications make multi-spectral image processing a relevant topic for research and development. Like in visible image processing, multi-spectral image processing needs tools and algorithms to handle information from various spectral bands. Furthermore, traditional tools such as local feature detection, which is the basis of many vision tasks such as visual odometry, image registration, or structure from motion, must be adjusted or reformulated to operate under new conditions. Traditional feature detection, description, and matching methods tend to underperform in multi-spectral settings, in comparison to mono-spectral settings, due to the natural differences between each spectral band.
The work in this thesis is focused on the local feature description problem when cross-spectral images are considered. In this context, this dissertation has three main contributions. Firstly, the work starts by proposing the usage of a combination of frequency and spatial information, in a multi-scale scheme, as feature description. Evaluations of this proposal, based on classical hand-made feature descriptors, and comparisons with state of the art cross-spectral approaches help to find and understand limitations of such strategy. Secondly, different convolutional neural network (CNN) based architectures are evaluated when used to describe cross-spectral image patches. Results showed that CNN-based methods, designed to work with visible monocular images, could be successfully applied to the description of images from two different spectral bands, with just minor modifications. In this framework, a novel CNN-based network model, specifically intended to describe image patches from two different spectral bands, is proposed. This network, referred to as Q-Net, outperforms state of the art in the cross-spectral domain, including both previous hand-made solutions as well as L2 CNN-based architectures. The third contribution of this dissertation is in the cross-spectral feature description application domain. The multispectral odometry problem is tackled showing a real application of cross-spectral descriptors
In addition to the three main contributions mentioned above, in this dissertation, two different multi-spectral datasets are generated and shared with the community to be used as benchmarks for further studies.

Abstract: Computer vision has gone through considerable changes in the last decade as neural networks have come into common use. As available computational capabilities have grown, neural networks have achieved breakthroughs in many computer vision tasks, and have even surpassed human performance in others. With accuracy being so high, focus has shifted to other issues and challenges. One research direction that saw a notable increase in interest is on lifelong learning systems. Such systems should be capable of efficiently performing tasks, identifying and learning new ones, and should moreover be able to deploy smaller versions of themselves which are experts on specific tasks. In this thesis, we contribute to research on lifelong learning and address the compression and adaptation of networks to small target domains, the incremental learning of networks faced with a variety of tasks, and finally the detection of out-of-distribution samples at inference time.
We explore how knowledge can be transferred from large pretrained models to more task-specific networks capable of running on smaller devices by extracting the most relevant information. Using a pretrained model provides more robust representations and a more stable initialization when learning a smaller task, which leads to higher performance and is known as domain adaptation. However, those models are too large for certain applications that need to be deployed on devices with limited memory and computational capacity. In this thesis we show that, after performing domain adaptation, some learned activations barely contribute to the predictions of the model. Therefore, we propose to apply network compression based on low-rank matrix decomposition using the activation statistics. This results in a significant reduction of the model size and the computational cost.
Like human intelligence, machine intelligence aims to have the ability to learn and remember knowledge. However, when a trained neural network is presented with learning a new task, it ends up forgetting previous ones. This is known as catastrophic forgetting and its avoidance is studied in continual learning. The work presented in this thesis extensively surveys continual learning techniques and presents an approach to avoid catastrophic forgetting in sequential task learning scenarios. Our technique is based on using ternary masks in order to update a network to new tasks, reusing the knowledge of previous ones while not forgetting anything about them. In contrast to earlier work, our masks are applied to the activations of each layer instead of the weights. This considerably reduces the number of parameters to be added for each new task. Furthermore, the analysis on a wide range of work on incremental learning without access to the task-ID, provides insight on current state-of-the-art approaches that focus on avoiding catastrophic forgetting by using regularization, rehearsal of previous tasks from a small memory, or compensating the task-recency bias.
Neural networks trained with a cross-entropy loss force the outputs of the model to tend toward a one-hot encoded vector. This leads to models being too overly confident when presented with images or classes that were not present in the training distribution. The capacity of a system to be aware of the boundaries of the learned tasks and identify anomalies or classes which have not been learned yet is key to lifelong learning and autonomous systems. In this thesis, we present a metric learning approach to out-of-distribution detection that learns the task at hand on an embedding space.