Abstract: The study of color vision has been aided by a whole battery of computational methods that attempt to describe the mechanisms that lead to our perception of colors in terms of the information-processing properties of the visual system. Their scope is highly interdisciplinary, linking apparently dissimilar disciplines such as mathematics, physics, computer science, neuroscience, cognitive science, and psychology. Since the sensation of color is a feature of our brains, computational approaches usually include biological features of neural systems in their descriptions, from retinal light-receptor interaction to subcortical color opponency, cortical signal decoding, and color categorization. They produce hypotheses that are usually tested by behavioral or psychophysical experiments.

Abstract: Clinical studies on atherosclerosis regression/progression performed by Intravascular Ultrasound analysis require the alignment of pullbacks of the same patient before and after clinical interventions. In this paper, a methodology for the automatic alignment of IVUS sequences based on the Dynamic Time Warping technique is proposed. The method is adapted to the specific IVUS alignment task by applying the non-rigid alignment technique to multidimensional morphological signals, and by introducing a sliding window approach together with a regularization term. To show the effectiveness of our method, an extensive validation is performed both on synthetic data and in-vivo IVUS sequences. The proposed method is robust to stent deployment and post dilation surgery and reaches an alignment error of approximately 0.7 mm for in-vivo data, which is comparable to the inter-observer variability.

Abstract: This paper describes an affect-responsive interactive photo-frame application that offers its user a different experience with every use. It relies on visual analysis of activity levels and facial expressions of its users to select responses from a database of short video segments. This ever-growing database is automatically prepared by an offline analysis of user-uploaded videos. The resulting system matches its user’s affect along dimensions of valence and arousal, and gradually adapts its response to each specific user. In an extended mode, two such systems are coupled and feed each other with visual content. The strengths and weaknesses of the system are assessed through a usability study, where a Wizard-of-Oz response logic is contrasted with the fully automatic system that uses affective and activity-based features, either alone, or in tandem.

Abstract: The investigation of spatio-temporal dynamics of bacterial cells and their molecular components requires automated image analysis tools to track cell shape properties and molecular component locations inside the cells. In the study of bacteria aging, the molecular components of interest are protein aggregates accumulated near bacteria boundaries. This particular location makes very ambiguous the correspondence between aggregates and cells, since computing accurately bacteria boundaries in phase-contrast time-lapse imaging is a challenging task. This paper proposes an active skeleton formulation for bacteria modelling which provides several advantages: an easy computation of shape properties (perimeter, length, thickness and orientation), an improved boundary accuracy in noisy images and a natural bacteria-centred coordinate system that permits the intrinsic location of molecular components inside the cell. Starting from an initial skeleton estimate, the medial axis of the bacterium is obtained by minimising an energy function which incorporates bacteria shape constraints. Experimental results on biological images and comparative evaluation of the performances validate the proposed approach for modelling cigar-shaped bacteria like Escherichia coli. The Image-J plugin of the proposed method can be found online at http://fluobactracker.inrialpes.fr.

Abstract: JCR Impact Factor 2010: 3.349
Background This study aimed to determine the proportion of cases with abnormal intestinal motility among patients with functional bowel disorders. To this end, we applied an original method, previously developed in our laboratory, for analysis of endoluminal images obtained by capsule endoscopy. This novel technology is based on computer vision and machine learning techniques.
 Methods The endoscopic capsule (Pillcam SB1; Given Imaging, Yokneam, Israel) was administered to 80 patients with functional bowel disorders and 70 healthy subjects. Endoluminal image analysis was performed with a computer vision program developed for the evaluation of contractile events (luminal occlusions and radial wrinkles), non-contractile patterns (open tunnel and smooth wall patterns), type of content (secretions, chyme) and motion of wall and contents. Normality range and discrimination of abnormal cases were established by a machine learning technique. Specifically, an iterative classifier (one-class support vector machine) was applied in a random population of 50 healthy subjects as a training set and the remaining subjects (20 healthy subjects and 80 patients) as a test set.
 Key Results The classifier identified as abnormal 29% of patients with functional diseases of the bowel (23 of 80), and as normal 97% of healthy subjects (68 of 70) (P < 0.05 by chi-squared test). Patients identified as abnormal clustered in two groups, which exhibited either a hyper- or a hypodynamic motility pattern. The motor behavior was unrelated to clinical features.
Conclusions &  Inferences With appropriate methodology, abnormal intestinal motility can be demonstrated in a significant proportion of patients with functional bowel disorders, implying a pathologic disturbance of gut physiology.