David Roche, Debora Gil, & Jesus Giraldo. (2012). Assessing agonist efficacy in an uncertain Em world. In A. Christopoulus and M. Bouvier (Ed.), 40th Keystone Symposia on mollecular and celular biology (79). Keystone Symposia.
Abstract: The operational model of agonism has been widely used for the analysis of agonist action since its formulation in 1983. The model includes the Em parameter, which is defined as the maximum response of the system. The methods for Em estimation provide Em values not significantly higher than the maximum responses achieved by full agonists. However, it has been found that that some classes of compounds as, for instance, superagonists and positive allosteric modulators can increase the full agonist maximum response, implying upper limits for Em and thereby posing doubts on the validity of Em estimates. Because of the correlation between Em and operational efficacy, τ, wrong Em estimates will yield wrong τ estimates.
In this presentation, the operational model of agonism and various methods for the simulation of allosteric modulation will be analyzed. Alternatives for curve fitting will be presented and discussed.
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Naveen Onkarappa, Sujay M. Veerabhadrappa, & Angel Sappa. (2012). Optical Flow in Onboard Applications: A Study on the Relationship Between Accuracy and Scene Texture. In 4th International Conference on Signal and Image Processing (Vol. 221, pp. 257–267).
Abstract: Optical flow has got a major role in making advanced driver assistance systems (ADAS) a reality. ADAS applications are expected to perform efficiently in all kinds of environments, those are highly probable, that one can drive the vehicle in different kinds of roads, times and seasons. In this work, we study the relationship of optical flow with different roads, that is by analyzing optical flow accuracy on different road textures. Texture measures such as TeX , TeX and TeX are evaluated for this purpose. Further, the relation of regularization weight to the flow accuracy in the presence of different textures is also analyzed. Additionally, we present a framework to generate synthetic sequences of different textures in ADAS scenarios with ground-truth optical flow.
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Alex Pardo, Albert Clapes, Sergio Escalera, & Oriol Pujol. (2013). Actions in Context: System for people with Dementia. In 2nd International Workshop on Citizen Sensor Networks (Citisen2013) at the European Conference on Complex Systems (pp. 3–14). Springer International Publishing.
Abstract: In the next forty years, the number of people living with dementia is expected to triple. In the last stages, people affected by this disease become dependent. This hinders the autonomy of the patient and has a huge social impact in time, money and effort. Given this scenario, we propose an ubiquitous system capable of recognizing daily specific actions. The system fuses and synchronizes data obtained from two complementary modalities – ambient and egocentric. The ambient approach consists in a fixed RGB-Depth camera for user and object recognition and user-object interaction, whereas the egocentric point of view is given by a personal area network (PAN) formed by a few wearable sensors and a smartphone, used for gesture recognition. The system processes multi-modal data in real-time, performing paralleled task recognition and modality synchronization, showing high performance recognizing subjects, objects, and interactions, showing its reliability to be applied in real case scenarios.
Keywords: Multi-modal data Fusion; Computer vision; Wearable sensors; Gesture recognition; Dementia
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S.Grau, Ana Puig, Sergio Escalera, & Maria Salamo. (2013). Intelligent Interactive Volume Classification. In Pacific Graphics (Vol. 32, pp. 23–28).
Abstract: This paper defines an intelligent and interactive framework to classify multiple regions of interest from the original data on demand, without requiring any preprocessing or previous segmentation. The proposed intelligent and interactive approach is divided in three stages: visualize, training and testing. First, users visualize and label some samples directly on slices of the volume. Training and testing are based on a framework of Error Correcting Output Codes and Adaboost classifiers that learn to classify each region the user has painted. Later, at the testing stage, each classifier is directly applied on the rest of samples and combined to perform multi-class labeling, being used in the final rendering. We also parallelized the training stage using a GPU-based implementation for
obtaining a rapid interaction and classification.
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Mohammad Rouhani, & Angel Sappa. (2012). Implicit Polynomial Representation through a Fast Fitting Error Estimation. TIP - IEEE Transactions on Image Processing, 21(4), 2089–2098.
Abstract: Impact Factor
This paper presents a simple distance estimation for implicit polynomial fitting. It is computed as the height of a simplex built between the point and the surface (i.e., a triangle in 2-D or a tetrahedron in 3-D), which is used as a coarse but reliable estimation of the orthogonal distance. The proposed distance can be described as a function of the coefficients of the implicit polynomial. Moreover, it is differentiable and has a smooth behavior . Hence, it can be used in any gradient-based optimization. In this paper, its use in a Levenberg-Marquardt framework is shown, which is particularly devoted for nonlinear least squares problems. The proposed estimation is a generalization of the gradient-based distance estimation, which is widely used in the literature. Experimental results, both in 2-D and 3-D data sets, are provided. Comparisons with state-of-the-art techniques are presented, showing the advantages of the proposed approach.
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M. Visani, Oriol Ramos Terrades, & Salvatore Tabbone. (2011). A Protocol to Characterize the Descriptive Power and the Complementarity of Shape Descriptors. IJDAR - International Journal on Document Analysis and Recognition, 14(1), 87–100.
Abstract: Most document analysis applications rely on the extraction of shape descriptors, which may be grouped into different categories, each category having its own advantages and drawbacks (O.R. Terrades et al. in Proceedings of ICDAR’07, pp. 227–231, 2007). In order to improve the richness of their description, many authors choose to combine multiple descriptors. Yet, most of the authors who propose a new descriptor content themselves with comparing its performance to the performance of a set of single state-of-the-art descriptors in a specific applicative context (e.g. symbol recognition, symbol spotting...). This results in a proliferation of the shape descriptors proposed in the literature. In this article, we propose an innovative protocol, the originality of which is to be as independent of the final application as possible and which relies on new quantitative and qualitative measures. We introduce two types of measures: while the measures of the first type are intended to characterize the descriptive power (in terms of uniqueness, distinctiveness and robustness towards noise) of a descriptor, the second type of measures characterizes the complementarity between multiple descriptors. Characterizing upstream the complementarity of shape descriptors is an alternative to the usual approach where the descriptors to be combined are selected by trial and error, considering the performance characteristics of the overall system. To illustrate the contribution of this protocol, we performed experimental studies using a set of descriptors and a set of symbols which are widely used by the community namely ART and SC descriptors and the GREC 2003 database.
Keywords: Document analysis; Shape descriptors; Symbol description; Performance characterization; Complementarity analysis
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Carles Sanchez. (2011). Tracheal ring detection in bronchoscopy (F. J. S. Debora Gil, Ed.) (Vol. 168). Master's thesis, , .
Abstract: Endoscopy is the process in which a camera is introduced inside a human.
Given that endoscopy provides realistic images (in contrast to other modalities) and allows non-invase minimal intervention procedures (which can aid in diagnosis and surgical interventions), its use has spreaded during last decades.
In this project we will focus on bronchoscopic procedures, during which the camera is introduced through the trachea in order to have a diagnostic of the patient. The diagnostic interventions are focused on: degree of stenosis (reduction in tracheal area), prosthesis or early diagnosis of tumors. In the first case, assessment of the luminal area and the calculation of the diameters of the tracheal rings are required. A main limitation is that all the process is done by hand,
which means that the doctor takes all the measurements and decisions just by looking at the screen. As far as we know there is no computational framework for helping the doctors in the diagnosis.
This project will consist of analysing bronchoscopic videos in order to extract useful information for the diagnostic of the degree of stenosis. In particular we will focus on segmentation of the tracheal rings. As a result of this project several strategies (for detecting tracheal rings) had been implemented in order to compare their performance.
Keywords: Bronchoscopy, tracheal ring, segmentation
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Hamdi Dibeklioglu, M.O. Hortas, I. Kosunen, P. Zuzánek, Albert Ali Salah, & Theo Gevers. (2011). Design and implementation of an affect-responsive interactive photo frame. JMUI - Journal on Multimodal User Interfaces, 81–95.
Abstract: This paper describes an affect-responsive interactive photo-frame application that offers its user a different experience with every use. It relies on visual analysis of activity levels and facial expressions of its users to select responses from a database of short video segments. This ever-growing database is automatically prepared by an offline analysis of user-uploaded videos. The resulting system matches its user’s affect along dimensions of valence and arousal, and gradually adapts its response to each specific user. In an extended mode, two such systems are coupled and feed each other with visual content. The strengths and weaknesses of the system are assessed through a usability study, where a Wizard-of-Oz response logic is contrasted with the fully automatic system that uses affective and activity-based features, either alone, or in tandem.
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A. Toet, M. Henselmans, M.P. Lucassen, & Theo Gevers. (2011). Emotional effects of dynamic textures. iPER - i-Perception, 969 – 991.
Abstract: This study explores the effects of various spatiotemporal dynamic texture characteristics on human emotions. The emotional experience of auditory (eg, music) and haptic repetitive patterns has been studied extensively. In contrast, the emotional experience of visual dynamic textures is still largely unknown, despite their natural ubiquity and increasing use in digital media. Participants watched a set of dynamic textures, representing either water or various different media, and self-reported their emotional experience. Motion complexity was found to have mildly relaxing and nondominant effects. In contrast, motion change complexity was found to be arousing and dominant. The speed of dynamics had arousing, dominant, and unpleasant effects. The amplitude of dynamics was also regarded as unpleasant. The regularity of the dynamics over the textures’ area was found to be uninteresting, nondominant, mildly relaxing, and mildly pleasant. The spatial scale of the dynamics had an unpleasant, arousing, and dominant effect, which was larger for textures with diverse content than for water textures. For water textures, the effects of spatial contrast were arousing, dominant, interesting, and mildly unpleasant. None of these effects were observed for textures of diverse content. The current findings are relevant for the design and synthesis of affective multimedia content and for affective scene indexing and retrieval.
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Marcel P. Lucassen, Theo Gevers, & Arjan Gijsenij. (2011). Texture Affects Color Emotion. CRA - Color Research & Applications, 36(6), 426–436.
Abstract: Several studies have recorded color emotions in subjects viewing uniform color (UC) samples. We conduct an experiment to measure and model how these color emotions change when texture is added to the color samples. Using a computer monitor, our subjects arrange samples along four scales: warm–cool, masculine–feminine, hard–soft, and heavy–light. Three sample types of increasing visual complexity are used: UC, grayscale textures, and color textures (CTs). To assess the intraobserver variability, the experiment is repeated after 1 week. Our results show that texture fully determines the responses on the Hard-Soft scale, and plays a role of decreasing weight for the masculine–feminine, heavy–light, and warm–cool scales. Using some 25,000 observer responses, we derive color emotion functions that predict the group-averaged scale responses from the samples' color and texture parameters. For UC samples, the accuracy of our functions is significantly higher (average R2 = 0.88) than that of previously reported functions applied to our data. The functions derived for CT samples have an accuracy of R2 = 0.80. We conclude that when textured samples are used in color emotion studies, the psychological responses may be strongly affected by texture. © 2010 Wiley Periodicals, Inc. Col Res Appl, 2010
Keywords: color;texture;color emotion;observer variability;ranking
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Albert Ali Salah, E. Pauwels, R. Tavenard, & Theo Gevers. (2010). T-Patterns Revisited: Mining for Temporal Patterns in Sensor Data. SENS - Sensors, 10(8), 7496–7513.
Abstract: The trend to use large amounts of simple sensors as opposed to a few complex sensors to monitor places and systems creates a need for temporal pattern mining algorithms to work on such data. The methods that try to discover re-usable and interpretable patterns in temporal event data have several shortcomings. We contrast several recent approaches to the problem, and extend the T-Pattern algorithm, which was previously applied for detection of sequential patterns in behavioural sciences. The temporal complexity of the T-pattern approach is prohibitive in the scenarios we consider. We remedy this with a statistical model to obtain a fast and robust algorithm to find patterns in temporal data. We test our algorithm on a recent database collected with passive infrared sensors with millions of events.
Keywords: sensor networks; temporal pattern extraction; T-patterns; Lempel-Ziv; Gaussian mixture model; MERL motion data
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Koen E.A. van de Sande, Theo Gevers, & C.G.M. Snoek. (2010). Evaluating Color Descriptors for Object and Scene Recognition. TPAMI - IEEE Transaction on Pattern Analysis and Machine Intelligence, 32(9), 1582–1596.
Abstract: Impact factor: 5.308
Image category recognition is important to access visual information on the level of objects and scene types. So far, intensity-based descriptors have been widely used for feature extraction at salient points. To increase illumination invariance and discriminative power, color descriptors have been proposed. Because many different descriptors exist, a structured overview is required of color invariant descriptors in the context of image category recognition. Therefore, this paper studies the invariance properties and the distinctiveness of color descriptors (software to compute the color descriptors from this paper is available from http://www.colordescriptors.com) in a structured way. The analytical invariance properties of color descriptors are explored, using a taxonomy based on invariance properties with respect to photometric transformations, and tested experimentally using a data set with known illumination conditions. In addition, the distinctiveness of color descriptors is assessed experimentally using two benchmarks, one from the image domain and one from the video domain. From the theoretical and experimental results, it can be derived that invariance to light intensity changes and light color changes affects category recognition. The results further reveal that, for light intensity shifts, the usefulness of invariance is category-specific. Overall, when choosing a single descriptor and no prior knowledge about the data set and object and scene categories is available, the OpponentSIFT is recommended. Furthermore, a combined set of color descriptors outperforms intensity-based SIFT and improves category recognition by 8 percent on the PASCAL VOC 2007 and by 7 percent on the Mediamill Challenge.
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J. Stöttinger, A. Hanbury, N. Sebe, & Theo Gevers. (2012). Spars Color Interest Points for Image Retrieval and Object Categorization. TIP - IEEE Transactions on Image Processing, 21(5), 2681–2692.
Abstract: Impact factor 2010: 2.92
IF 2011/2012?: 3.32
Interest point detection is an important research area in the field of image processing and computer vision. In particular, image retrieval and object categorization heavily rely on interest point detection from which local image descriptors are computed for image matching. In general, interest points are based on luminance, and color has been largely ignored. However, the use of color increases the distinctiveness of interest points. The use of color may therefore provide selective search reducing the total number of interest points used for image matching. This paper proposes color interest points for sparse image representation. To reduce the sensitivity to varying imaging conditions, light-invariant interest points are introduced. Color statistics based on occurrence probability lead to color boosted points, which are obtained through saliency-based feature selection. Furthermore, a principal component analysis-based scale selection method is proposed, which gives a robust scale estimation per interest point. From large-scale experiments, it is shown that the proposed color interest point detector has higher repeatability than a luminance-based one. Furthermore, in the context of image retrieval, a reduced and predictable number of color features show an increase in performance compared to state-of-the-art interest points. Finally, in the context of object recognition, for the Pascal VOC 2007 challenge, our method gives comparable performance to state-of-the-art methods using only a small fraction of the features, reducing the computing time considerably.
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R. Valenti, N. Sebe, & Theo Gevers. (2012). What are you looking at? Improving Visual gaze Estimation by Saliency. IJCV - International Journal of Computer Vision, 98(3), 324–334.
Abstract: Impact factor 2010: 5.15
Impact factor 2011/12?: 5.36
In this paper we present a novel mechanism to obtain enhanced gaze estimation for subjects looking at a scene or an image. The system makes use of prior knowledge about the scene (e.g. an image on a computer screen), to define a probability map of the scene the subject is gazing at, in order to find the most probable location. The proposed system helps in correcting the fixations which are erroneously estimated by the gaze estimation device by employing a saliency framework to adjust the resulting gaze point vector. The system is tested on three scenarios: using eye tracking data, enhancing a low accuracy webcam based eye tracker, and using a head pose tracker. The correlation between the subjects in the commercial eye tracking data is improved by an average of 13.91%. The correlation on the low accuracy eye gaze tracker is improved by 59.85%, and for the head pose tracker we obtain an improvement of 10.23%. These results show the potential of the system as a way to enhance and self-calibrate different visual gaze estimation systems.
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R. Valenti, & Theo Gevers. (2012). Accurate Eye Center Location through Invariant Isocentric Patterns. TPAMI - IEEE Transaction on Pattern Analysis and Machine Intelligence, 34(9), 1785–1798.
Abstract: Impact factor 2010: 5.308
Impact factor 2011/12?: 5.96
Locating the center of the eyes allows for valuable information to be captured and used in a wide range of applications. Accurate eye center location can be determined using commercial eye-gaze trackers, but additional constraints and expensive hardware make these existing solutions unattractive and impossible to use on standard (i.e., visible wavelength), low-resolution images of eyes. Systems based solely on appearance are proposed in the literature, but their accuracy does not allow us to accurately locate and distinguish eye centers movements in these low-resolution settings. Our aim is to bridge this gap by locating the center of the eye within the area of the pupil on low-resolution images taken from a webcam or a similar device. The proposed method makes use of isophote properties to gain invariance to linear lighting changes (contrast and brightness), to achieve in-plane rotational invariance, and to keep low-computational costs. To further gain scale invariance, the approach is applied to a scale space pyramid. In this paper, we extensively test our approach for its robustness to changes in illumination, head pose, scale, occlusion, and eye rotation. We demonstrate that our system can achieve a significant improvement in accuracy over state-of-the-art techniques for eye center location in standard low-resolution imagery.
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