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	Author	Bojana Gajic; Ariel Amato; Ramon Baldrich; Joost Van de Weijer; Carlo Gatta
	Title	Area Under the ROC Curve Maximization for Metric Learning			Type	Conference Article
	Year	2022	Publication	CVPR 2022 Workshop on Efficien Deep Learning for Computer Vision (ECV 2022, 5th Edition)	Abbreviated Journal
	Volume		Issue		Pages
	Keywords	Training; Computer vision; Conferences; Area measurement; Benchmark testing; Pattern recognition
	Abstract	Most popular metric learning losses have no direct relation with the evaluation metrics that are subsequently applied to evaluate their performance. We hypothesize that training a metric learning model by maximizing the area under the ROC curve (which is a typical performance measure of recognition systems) can induce an implicit ranking suitable for retrieval problems. This hypothesis is supported by previous work that proved that a curve dominates in ROC space if and only if it dominates in Precision-Recall space. To test this hypothesis, we design and maximize an approximated, derivable relaxation of the area under the ROC curve. The proposed AUC loss achieves state-of-the-art results on two large scale retrieval benchmark datasets (Stanford Online Products and DeepFashion In-Shop). Moreover, the AUC loss achieves comparable performance to more complex, domain specific, state-of-the-art methods for vehicle re-identification.
	Address	New Orleans, USA; 20 June 2022
	Corporate Author				Thesis
	Publisher		Place of Publication		Editor
	Language		Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN		ISBN		Medium
	Area		Expedition		Conference	CVPRW
	Notes	CIC; LAMP;			Approved	no
	Call Number	Admin @ si @ GAB2022			Serial	3700
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	Author	Y. Mori; M.Misawa; Jorge Bernal; M. Bretthauer; S.Kudo; A. Rastogi; Gloria Fernandez Esparrach
	Title	Artificial Intelligence for Disease Diagnosis-the Gold Standard Challenge			Type	Journal Article
	Year	2022	Publication	Gastrointestinal Endoscopy	Abbreviated Journal
	Volume	96	Issue	2	Pages	370-372
	Keywords
	Abstract
	Address
	Corporate Author				Thesis
	Publisher		Place of Publication		Editor
	Language		Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN		ISBN		Medium
	Area		Expedition		Conference
	Notes	ISE			Approved	no
	Call Number	Admin @ si @ MMB2022			Serial	3701
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	Author	Juan Borrego-Carazo; Carles Sanchez; David Castells; Jordi Carrabina; Debora Gil
	Title	BronchoPose: an analysis of data and model configuration for vision-based bronchoscopy pose estimation			Type	Journal Article
	Year	2023	Publication	Computer Methods and Programs in Biomedicine	Abbreviated Journal	CMPB
	Volume	228	Issue		Pages	107241
	Keywords	Videobronchoscopy guiding; Deep learning; Architecture optimization; Datasets; Standardized evaluation framework; Pose estimation
	Abstract	Vision-based bronchoscopy (VB) models require the registration of the virtual lung model with the frames from the video bronchoscopy to provide effective guidance during the biopsy. The registration can be achieved by either tracking the position and orientation of the bronchoscopy camera or by calibrating its deviation from the pose (position and orientation) simulated in the virtual lung model. Recent advances in neural networks and temporal image processing have provided new opportunities for guided bronchoscopy. However, such progress has been hindered by the lack of comparative experimental conditions. In the present paper, we share a novel synthetic dataset allowing for a fair comparison of methods. Moreover, this paper investigates several neural network architectures for the learning of temporal information at different levels of subject personalization. In order to improve orientation measurement, we also present a standardized comparison framework and a novel metric for camera orientation learning. Results on the dataset show that the proposed metric and architectures, as well as the standardized conditions, provide notable improvements to current state-of-the-art camera pose estimation in video bronchoscopy.
	Address
	Corporate Author				Thesis
	Publisher	Elsevier	Place of Publication		Editor
	Language		Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN		ISBN		Medium
	Area		Expedition		Conference
	Notes	IAM;			Approved	no
	Call Number	Admin @ si @ BSC2023			Serial	3702
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	Author	Javad Zolfaghari Bengar; Joost Van de Weijer; Laura Lopez-Fuentes; Bogdan Raducanu
	Title	Class-Balanced Active Learning for Image Classification			Type	Conference Article
	Year	2022	Publication	Winter Conference on Applications of Computer Vision	Abbreviated Journal
	Volume		Issue		Pages
	Keywords
	Abstract	Active learning aims to reduce the labeling effort that is required to train algorithms by learning an acquisition function selecting the most relevant data for which a label should be requested from a large unlabeled data pool. Active learning is generally studied on balanced datasets where an equal amount of images per class is available. However, real-world datasets suffer from severe imbalanced classes, the so called long-tail distribution. We argue that this further complicates the active learning process, since the imbalanced data pool can result in suboptimal classifiers. To address this problem in the context of active learning, we proposed a general optimization framework that explicitly takes class-balancing into account. Results on three datasets showed that the method is general (it can be combined with most existing active learning algorithms) and can be effectively applied to boost the performance of both informative and representative-based active learning methods. In addition, we showed that also on balanced datasets our method 1 generally results in a performance gain.
	Address	Virtual; Waikoloa; Hawai; USA; January 2022
	Corporate Author				Thesis
	Publisher		Place of Publication		Editor
	Language		Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN		ISBN		Medium
	Area		Expedition		Conference	WACV
	Notes	LAMP; 602.200; 600.147; 600.120			Approved	no
	Call Number	Admin @ si @ ZWL2022			Serial	3703
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	Author	Alex Gomez-Villa; Bartlomiej Twardowski; Lu Yu; Andrew Bagdanov; Joost Van de Weijer
	Title	Continually Learning Self-Supervised Representations With Projected Functional Regularization			Type	Conference Article
	Year	2022	Publication	CVPR 2022 Workshop on Continual Learning (CLVision, 3rd Edition)	Abbreviated Journal
	Volume		Issue		Pages	3866-3876
	Keywords	Computer vision; Conferences; Self-supervised learning; Image representation; Pattern recognition
	Abstract	Recent self-supervised learning methods are able to learn high-quality image representations and are closing the gap with supervised approaches. However, these methods are unable to acquire new knowledge incrementally – they are, in fact, mostly used only as a pre-training phase over IID data. In this work we investigate self-supervised methods in continual learning regimes without any replay mechanism. We show that naive functional regularization,also known as feature distillation, leads to lower plasticity and limits continual learning performance. Instead, we propose Projected Functional Regularization in which a separate temporal projection network ensures that the newly learned feature space preserves information of the previous one, while at the same time allowing for the learning of new features. This prevents forgetting while maintaining the plasticity of the learner. Comparison with other incremental learning approaches applied to self-supervision demonstrates that our method obtains competitive performance in different scenarios and on multiple datasets.
	Address	New Orleans, USA; 20 June 2022
	Corporate Author				Thesis
	Publisher		Place of Publication		Editor
	Language		Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN		ISBN		Medium
	Area		Expedition		Conference	CVPRW
	Notes	LAMP: 600.147; 600.120			Approved	no
	Call Number	Admin @ si @ GTY2022			Serial	3704
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	Author	Jose Luis Gomez; Gabriel Villalonga; Antonio Lopez
	Title	Co-Training for Unsupervised Domain Adaptation of Semantic Segmentation Models			Type	Journal Article
	Year	2023	Publication	Sensors – Special Issue on “Machine Learning for Autonomous Driving Perception and Prediction”	Abbreviated Journal	SENS
	Volume	23	Issue	2	Pages	621
	Keywords	Domain adaptation; semi-supervised learning; Semantic segmentation; Autonomous driving
	Abstract	Semantic image segmentation is a central and challenging task in autonomous driving, addressed by training deep models. Since this training draws to a curse of human-based image labeling, using synthetic images with automatically generated labels together with unlabeled real-world images is a promising alternative. This implies to address an unsupervised domain adaptation (UDA) problem. In this paper, we propose a new co-training procedure for synth-to-real UDA of semantic segmentation models. It consists of a self-training stage, which provides two domain-adapted models, and a model collaboration loop for the mutual improvement of these two models. These models are then used to provide the final semantic segmentation labels (pseudo-labels) for the real-world images. The overall procedure treats the deep models as black boxes and drives their collaboration at the level of pseudo-labeled target images, i.e., neither modifying loss functions is required, nor explicit feature alignment. We test our proposal on standard synthetic and real-world datasets for on-board semantic segmentation. Our procedure shows improvements ranging from ∼13 to ∼26 mIoU points over baselines, so establishing new state-of-the-art results.
	Address
	Corporate Author				Thesis
	Publisher		Place of Publication		Editor
	Language		Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN		ISBN		Medium
	Area		Expedition		Conference
	Notes	ADAS; no proj			Approved	no
	Call Number	Admin @ si @ GVL2023			Serial	3705
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	Author	Reuben Dorent; Aaron Kujawa; Marina Ivory; Spyridon Bakas; Nikola Rieke; Samuel Joutard; Ben Glocker; Jorge Cardoso; Marc Modat; Kayhan Batmanghelich; Arseniy Belkov; Maria Baldeon Calisto; Jae Won Choi; Benoit M. Dawant; Hexin Dong; Sergio Escalera; Yubo Fan; Lasse Hansen; Mattias P. Heinrich; Smriti Joshi; Victoriya Kashtanova; Hyeon Gyu Kim; Satoshi Kondo; Christian N. Kruse; Susana K. Lai-Yuen; Hao Li; Han Liu; Buntheng Ly; Ipek Oguz; Hyungseob Shin; Boris Shirokikh; Zixian Su; Guotai Wang; Jianghao Wu; Yanwu Xu; Kai Yao; Li Zhang; Sebastien Ourselin,
	Title	CrossMoDA 2021 challenge: Benchmark of Cross-Modality Domain Adaptation techniques for Vestibular Schwannoma and Cochlea Segmentation			Type	Journal Article
	Year	2023	Publication	Medical Image Analysis	Abbreviated Journal	MIA
	Volume	83	Issue		Pages	102628
	Keywords	Domain Adaptation; Segmen tation; Vestibular Schwnannoma
	Abstract	Domain Adaptation (DA) has recently raised strong interests in the medical imaging community. While a large variety of DA techniques has been proposed for image segmentation, most of these techniques have been validated either on private datasets or on small publicly available datasets. Moreover, these datasets mostly addressed single-class problems. To tackle these limitations, the Cross-Modality Domain Adaptation (crossMoDA) challenge was organised in conjunction with the 24th International Conference on Medical Image Computing and Computer Assisted Intervention (MICCAI 2021). CrossMoDA is the first large and multi-class benchmark for unsupervised cross-modality DA. The challenge's goal is to segment two key brain structures involved in the follow-up and treatment planning of vestibular schwannoma (VS): the VS and the cochleas. Currently, the diagnosis and surveillance in patients with VS are performed using contrast-enhanced T1 (ceT1) MRI. However, there is growing interest in using non-contrast sequences such as high-resolution T2 (hrT2) MRI. Therefore, we created an unsupervised cross-modality segmentation benchmark. The training set provides annotated ceT1 (N=105) and unpaired non-annotated hrT2 (N=105). The aim was to automatically perform unilateral VS and bilateral cochlea segmentation on hrT2 as provided in the testing set (N=137). A total of 16 teams submitted their algorithm for the evaluation phase. The level of performance reached by the top-performing teams is strikingly high (best median Dice – VS:88.4%; Cochleas:85.7%) and close to full supervision (median Dice – VS:92.5%; Cochleas:87.7%). All top-performing methods made use of an image-to-image translation approach to transform the source-domain images into pseudo-target-domain images. A segmentation network was then trained using these generated images and the manual annotations provided for the source image.
	Address
	Corporate Author				Thesis
	Publisher		Place of Publication		Editor
	Language		Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN		ISBN		Medium
	Area		Expedition		Conference
	Notes	HUPBA			Approved	no
	Call Number	Admin @ si @ DKI2023			Serial	3706
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	Author	Julio C. S. Jacques Junior; Yagmur Gucluturk; Marc Perez; Umut Guçlu; Carlos Andujar; Xavier Baro; Hugo Jair Escalante; Isabelle Guyon; Marcel A. J. van Gerven; Rob van Lier; Sergio Escalera
	Title	First Impressions: A Survey on Vision-Based Apparent Personality Trait Analysis			Type	Journal Article
	Year	2022	Publication	IEEE Transactions on Affective Computing	Abbreviated Journal	TAC
	Volume	13	Issue	1	Pages	75-95
	Keywords	Personality computing; first impressions; person perception; big-five; subjective bias; computer vision; machine learning; nonverbal signals; facial expression; gesture; speech analysis; multi-modal recognition
	Abstract	Personality analysis has been widely studied in psychology, neuropsychology, and signal processing fields, among others. From the past few years, it also became an attractive research area in visual computing. From the computational point of view, by far speech and text have been the most considered cues of information for analyzing personality. However, recently there has been an increasing interest from the computer vision community in analyzing personality from visual data. Recent computer vision approaches are able to accurately analyze human faces, body postures and behaviors, and use these information to infer apparent personality traits. Because of the overwhelming research interest in this topic, and of the potential impact that this sort of methods could have in society, we present in this paper an up-to-date review of existing vision-based approaches for apparent personality trait recognition. We describe seminal and cutting edge works on the subject, discussing and comparing their distinctive features and limitations. Future venues of research in the field are identified and discussed. Furthermore, aspects on the subjectivity in data labeling/evaluation, as well as current datasets and challenges organized to push the research on the field are reviewed.
	Address	1 Jan.-March 2022
	Corporate Author				Thesis
	Publisher		Place of Publication		Editor
	Language		Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN		ISBN		Medium
	Area		Expedition		Conference
	Notes	HuPBA			Approved	no
	Call Number	Admin @ si @ JGP2022			Serial	3724
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	Author	Gemma Rotger; Francesc Moreno-Noguer; Felipe Lumbreras; Antonio Agudo
	Title	Single view facial hair 3D reconstruction			Type	Conference Article
	Year	2019	Publication	9th Iberian Conference on Pattern Recognition and Image Analysis	Abbreviated Journal
	Volume	11867	Issue		Pages	423-436
	Keywords	3D Vision; Shape Reconstruction; Facial Hair Modeling
	Abstract	n this work, we introduce a novel energy-based framework that addresses the challenging problem of 3D reconstruction of facial hair from a single RGB image. To this end, we identify hair pixels over the image via texture analysis and then determine individual hair fibers that are modeled by means of a parametric hair model based on 3D helixes. We propose to minimize an energy composed of several terms, in order to adapt the hair parameters that better fit the image detections. The final hairs respond to the resulting fibers after a post-processing step where we encourage further realism. The resulting approach generates realistic facial hair fibers from solely an RGB image without assuming any training data nor user interaction. We provide an experimental evaluation on real-world pictures where several facial hair styles and image conditions are observed, showing consistent results and establishing a comparison with respect to competing approaches.
	Address	Madrid; July 2019
	Corporate Author				Thesis
	Publisher		Place of Publication		Editor
	Language		Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title	LNCS
	Series Volume		Series Issue		Edition
	ISSN		ISBN		Medium
	Area		Expedition		Conference	IbPRIA
	Notes	MSIAU; 600.086; 600.130; 600.122			Approved	no
	Call Number	Admin @ si @			Serial	3707
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	Author	Gemma Rotger; Francesc Moreno-Noguer; Felipe Lumbreras; Antonio Agudo
	Title	Detailed 3D face reconstruction from a single RGB image			Type	Journal
	Year	2019	Publication	Journal of WSCG	Abbreviated Journal	JWSCG
	Volume	27	Issue	2	Pages	103-112
	Keywords	3D Wrinkle Reconstruction; Face Analysis, Optimization.
	Abstract	This paper introduces a method to obtain a detailed 3D reconstruction of facial skin from a single RGB image. To this end, we propose the exclusive use of an input image without requiring any information about the observed material nor training data to model the wrinkle properties. They are detected and characterized directly from the image via a simple and effective parametric model, determining several features such as location, orientation, width, and height. With these ingredients, we propose to minimize a photometric error to retrieve the final detailed 3D map, which is initialized by current techniques based on deep learning. In contrast with other approaches, we only require estimating a depth parameter, making our approach fast and intuitive. Extensive experimental evaluation is presented in a wide variety of synthetic and real images, including different skin properties and facial expressions. In all cases, our method outperforms the current approaches regarding 3D reconstruction accuracy, providing striking results for both large and fine wrinkles.
	Address	2019/11
	Corporate Author				Thesis
	Publisher		Place of Publication		Editor
	Language		Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN		ISBN		Medium
	Area		Expedition		Conference
	Notes	MSIAU; 600.086; 600.130; 600.122			Approved	no
	Call Number	Admin @ si @			Serial	3708
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	Author	Bojana Gajic; Ramon Baldrich
	Title	Cross-domain fashion image retrieval			Type	Conference Article
	Year	2018	Publication	CVPR 2018 Workshop on Women in Computer Vision (WiCV 2018, 4th Edition)	Abbreviated Journal
	Volume		Issue		Pages	19500-19502
	Keywords
	Abstract	Cross domain image retrieval is a challenging task that implies matching images from one domain to their pairs from another domain. In this paper we focus on fashion image retrieval, which involves matching an image of a fashion item taken by users, to the images of the same item taken in controlled condition, usually by professional photographer. When facing this problem, we have different products in train and test time, and we use triplet loss to train the network. We stress the importance of proper training of simple architecture, as well as adapting general models to the specific task.
	Address	Salt Lake City, USA; 22 June 2018
	Corporate Author				Thesis
	Publisher		Place of Publication		Editor
	Language		Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN		ISBN		Medium
	Area		Expedition		Conference	CVPRW
	Notes	CIC; 600.087			Approved	no
	Call Number	Admin @ si @			Serial	3709
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	Author	Bojana Gajic; Eduard Vazquez; Ramon Baldrich
	Title	Evaluation of Deep Image Descriptors for Texture Retrieval			Type	Conference Article
	Year	2017	Publication	Proceedings of the 12th International Joint Conference on Computer Vision, Imaging and Computer Graphics Theory and Applications (VISIGRAPP 2017)	Abbreviated Journal
	Volume		Issue		Pages	251-257
	Keywords	Texture Representation; Texture Retrieval; Convolutional Neural Networks; Psychophysical Evaluation
	Abstract	The increasing complexity learnt in the layers of a Convolutional Neural Network has proven to be of great help for the task of classification. The topic has received great attention in recently published literature. Nonetheless, just a handful of works study low-level representations, commonly associated with lower layers. In this paper, we explore recent findings which conclude, counterintuitively, the last layer of the VGG convolutional network is the best to describe a low-level property such as texture. To shed some light on this issue, we are proposing a psychophysical experiment to evaluate the adequacy of different layers of the VGG network for texture retrieval. Results obtained suggest that, whereas the last convolutional layer is a good choice for a specific task of classification, it might not be the best choice as a texture descriptor, showing a very poor performance on texture retrieval. Intermediate layers show the best performance, showing a good combination of basic filters, as in the primary visual cortex, and also a degree of higher level information to describe more complex textures.
	Address	Porto, Portugal; 27 February – 1 March 2017
	Corporate Author				Thesis
	Publisher		Place of Publication		Editor
	Language		Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN		ISBN		Medium
	Area		Expedition		Conference	VISIGRAPP
	Notes	CIC; 600.087			Approved	no
	Call Number	Admin @ si @			Serial	3710
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	Author	Jon Almazan; Bojana Gajic; Naila Murray; Diane Larlus
	Title	Re-ID done right: towards good practices for person re-identification			Type	Miscellaneous
	Year	2018	Publication	Arxiv	Abbreviated Journal
	Volume		Issue		Pages
	Keywords
	Abstract	Training a deep architecture using a ranking loss has become standard for the person re-identification task. Increasingly, these deep architectures include additional components that leverage part detections, attribute predictions, pose estimators and other auxiliary information, in order to more effectively localize and align discriminative image regions. In this paper we adopt a different approach and carefully design each component of a simple deep architecture and, critically, the strategy for training it effectively for person re-identification. We extensively evaluate each design choice, leading to a list of good practices for person re-identification. By following these practices, our approach outperforms the state of the art, including more complex methods with auxiliary components, by large margins on four benchmark datasets. We also provide a qualitative analysis of our trained representation which indicates that, while compact, it is able to capture information from localized and discriminative regions, in a manner akin to an implicit attention mechanism.
	Address	January 2018
	Corporate Author				Thesis
	Publisher		Place of Publication		Editor
	Language		Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN		ISBN		Medium
	Area		Expedition		Conference
	Notes				Approved	no
	Call Number	Admin @ si @			Serial	3711
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	Author	Oriol Ramos Terrades; Albert Berenguel; Debora Gil
	Title	A Flexible Outlier Detector Based on a Topology Given by Graph Communities			Type	Journal Article
	Year	2022	Publication	Big Data Research	Abbreviated Journal	BDR
	Volume	29	Issue		Pages	100332
	Keywords	Classification algorithms; Detection algorithms; Description of feature space local structure; Graph communities; Machine learning algorithms; Outlier detectors
	Abstract	Outlier detection is essential for optimal performance of machine learning methods and statistical predictive models. Their detection is especially determinant in small sample size unbalanced problems, since in such settings outliers become highly influential and significantly bias models. This particular experimental settings are usual in medical applications, like diagnosis of rare pathologies, outcome of experimental personalized treatments or pandemic emergencies. In contrast to population-based methods, neighborhood based local approaches compute an outlier score from the neighbors of each sample, are simple flexible methods that have the potential to perform well in small sample size unbalanced problems. A main concern of local approaches is the impact that the computation of each sample neighborhood has on the method performance. Most approaches use a distance in the feature space to define a single neighborhood that requires careful selection of several parameters, like the number of neighbors. This work presents a local approach based on a local measure of the heterogeneity of sample labels in the feature space considered as a topological manifold. Topology is computed using the communities of a weighted graph codifying mutual nearest neighbors in the feature space. This way, we provide with a set of multiple neighborhoods able to describe the structure of complex spaces without parameter fine tuning. The extensive experiments on real-world and synthetic data sets show that our approach outperforms, both, local and global strategies in multi and single view settings.
	Address	August 28, 2022
	Corporate Author				Thesis
	Publisher		Place of Publication		Editor
	Language		Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN		ISBN		Medium
	Area		Expedition		Conference
	Notes	DAG; IAM; 600.140; 600.121; 600.139; 600.145; 600.159			Approved	no
	Call Number	Admin @ si @ RBG2022a			Serial	3718
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	Author	Mireia Sole; Joan Blanco; Debora Gil; Oliver Valero; B. Cardenas; G. Fonseka; E. Anton; Alvaro Pascual; Richard Frodsham; Zaida Sarrate
	Title	Time to match; when do homologous chromosomes become closer?			Type	Journal Article
	Year	2022	Publication	Chromosoma	Abbreviated Journal	CHRO
	Volume		Issue		Pages
	Keywords
	Abstract	In most eukaryotes, pairing of homologous chromosomes is an essential feature of meiosis that ensures homologous recombination and segregation. However, when the pairing process begins, it is still under investigation. Contrasting data exists in Mus musculus, since both leptotene DSB-dependent and preleptotene DSB-independent mechanisms have been described. To unravel this contention, we examined homologous pairing in pre-meiotic and meiotic Mus musculus cells using a threedimensional fuorescence in situ hybridization-based protocol, which enables the analysis of the entire karyotype using DNA painting probes. Our data establishes in an unambiguously manner that 73.83% of homologous chromosomes are already paired at premeiotic stages (spermatogonia-early preleptotene spermatocytes). The percentage of paired homologous chromosomes increases to 84.60% at mid-preleptotene-zygotene stage, reaching 100% at pachytene stage. Importantly, our results demonstrate a high percentage of homologous pairing observed before the onset of meiosis; this pairing does not occur randomly, as the percentage was higher than that observed in somatic cells (19.47%) and between nonhomologous chromosomes (41.1%). Finally, we have also observed that premeiotic homologous pairing is asynchronous and independent of the chromosome size, GC content, or presence of NOR regions.
	Address	August, 2022
	Corporate Author				Thesis
	Publisher		Place of Publication		Editor
	Language		Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN		ISBN		Medium
	Area		Expedition		Conference
	Notes	IAM; 601.139; 600.145; 600.096			Approved	no
	Call Number	Admin @ si @ SBG2022			Serial	3719
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