Abstract: Recent advances in endoscopic devices have increased their use for minimal invasive diagnostic and intervention procedures. Among all endoscopic modalities, bronchoscopy is one of the most frequent with around 261 millions of procedures per year. Although the use of bronchoscopy is spread among clinical facilities it presents some drawbacks, being the visual inspection for the assessment of anatomical measurements the most prevalent of them. In
particular, inaccuracies in the estimation of the degree of stenosis (the percentage of obstructed airway) decreases its diagnostic yield and might lead to erroneous treatments. An objective computation of tracheal stenosis in bronchoscopy videos would constitute a breakthrough for this non-invasive technique and a reduction in treatment cost.
This thesis settles the first steps towards on-line reliable extraction of anatomical information from videobronchoscopy for computation of objective measures. In particular, we focus on the computation of the degree of stenosis, which is obtained by comparing the area delimited by a healthy tracheal ring and the stenosed lumen. Reliable extraction of airway structures in interventional videobronchoscopy is a challenging task. This is mainly due to the large variety of acquisition conditions (positions and illumination), devices (different digitalizations) and in videos acquired at the operating room the unpredicted presence of surgical devices (such as probe ends). This thesis contributes to on-line stenosis assessment in several ways. We
propose a parametric strategy for the extraction of lumen and tracheal rings regions based on the characterization of their geometry and appearance that guide a deformable model. The geometric and appearance characterization is based on a physical model describing the way bronchoscopy images are obtained and includes local and global descriptions. In order to ensure a systematic applicability we present a statistical framework to select the optimal
parameters of our method. Experiments perform on the first public annotated database, show that the performance of our method is comparable to the one provided by clinicians and its computation time allows for a on-line implementation in the operating room.

Abstract: In this work, we develop a generic framework that is able to handle the document retrieval problem in various scenarios such as searching for full page matches or retrieving the counterparts for specific document areas, focusing on their structural similarity or letting their visual resemblance to play a dominant role. Based on the spatial indexing technique, we propose to search for matches of local key-region pairs carrying both structural and visual information from the collection while a scheme allowing to adjust the relative contribution of structural and visual similarity is presented.
Based on the fact that the structure of documents is tightly linked with the distance among their elements, we firstly introduce an efficient detector named Distance Transform based Maximally Stable Extremal Regions (DTMSER). We illustrate that this detector is able to efficiently extract the structure of a document image as a dendrogram (hierarchical tree) of multi-scale key-regions that roughly correspond to letters, words and paragraphs. We demonstrate that, without benefiting from the structure information, the key-regions extracted by the DTMSER algorithm achieve better results comparing with state-of-the-art methods while much less amount of key-regions are employed.
We subsequently propose a pair-wise Bag of Words (BoW) framework to efficiently embed the explicit structure extracted by the DTMSER algorithm. We represent each document as a list of key-region pairs that correspond to the edges in the dendrogram where inclusion relationship is encoded. By employing those structural key-region pairs as the pooling elements for generating the histogram of features, the proposed method is able to encode the explicit inclusion relations into a BoW representation. The experimental results illustrate that the pair-wise BoW, powered by the embedded structural information, achieves remarkable improvement over the conventional BoW and spatial pyramidal BoW methods.
To handle various retrieval scenarios in one framework, we propose to directly query a series of key-region pairs, carrying both structure and visual information, from the collection. We introduce the spatial indexing techniques to the document retrieval community to speed up the structural relationship computation for key-region pairs. We firstly test the proposed framework in a full page retrieval scenario where structurally similar matches are expected. In this case, the pair-wise querying method achieves notable improvement over the BoW and spatial pyramidal BoW frameworks. Furthermore, we illustrate that the proposed method is also able to handle focused retrieval situations where the queries are defined as a specific interesting partial areas of the images. We examine our method on two types of focused queries: structure-focused and exact queries. The experimental results show that, the proposed generic framework obtains nearly perfect precision on both types of focused queries while it is the first framework able to tackle structure-focused queries, setting a new state of the art in the field.
Besides, we introduce a line verification method to check the spatial consistency among the matched key-region pairs. We propose a computationally efficient version of line verification through a two step implementation. We first compute tentative localizations of the query and subsequently employ them to divide the matched key-region pairs into several groups, then line verification is performed within each group while more precise bounding boxes are computed. We demonstrate that, comparing with the standard approach (based on RANSAC), the line verification proposed generally achieves much higher recall with slight loss on precision on specific queries.

Abstract: Intrinsic image decomposition is a challenging problem that consists in separating an image into its physical characteristics: reflectance and shading. This problem can be solved in different ways, but most methods have combined information from several visual cues. In this work we describe an extension of an existing method proposed by Serra et al. which considers two color descriptors and combines them by means of a Markov Random Field. We analyze in depth the weak points of the method and we explore more possibilities to use in both descriptors. The proposed extension depends on the combination of the cues considered to overcome some of the limitations of the original method. Our approach is tested on the MIT dataset and Beigpour et al. dataset, which contain images of real objects acquired under controlled conditions and synthetic images respectively, with their corresponding ground truth.

Abstract: Describing textures is a challenging problem in computer vision and pattern recognition. The classification problem involves assigning a category label to the texture class it belongs to. Several factors such as variations in scale, illumination and viewpoint make the problem of texture description extremely challenging. A variety of histogram based texture representations exists in literature.
However, combining multiple texture descriptors and assessing their complementarity is still an open research problem. In this paper, we first show that combining multiple local texture descriptors significantly improves the recognition performance compared to using a single best method alone. This
gain in performance is achieved at the cost of high-dimensional final image representation. To counter this problem, we propose to use an information-theoretic compression technique to obtain a compact texture description without any significant loss in accuracy. In addition, we perform a comprehensive
evaluation of pure color descriptors, popular in object recognition, for the problem of texture classification. Experiments are performed on four challenging texture datasets namely, KTH-TIPS-2a, KTH-TIPS-2b, FMD and Texture-10. The experiments clearly demonstrate that our proposed compact multi-texture approach outperforms the single best texture method alone. In all cases, discriminative color names outperforms other color features for texture classification. Finally, we show that combining discriminative color names with compact texture representation outperforms state-of-the-art methods by 7:8%, 4:3% and 5:0% on KTH-TIPS-2a, KTH-TIPS-2b and Texture-10 datasets respectively.

Abstract: Change detection is the most important task for video surveillance analytics such as foreground and anomaly detection. Current foreground detectors learn models from annotated images since the goal is to generate a robust foreground model able to detect changes in all possible scenarios. Unfortunately, manual labelling is very expensive. Most advanced supervised learning techniques based on generic object detection datasets currently exhibit very poor performance when applied to surveillance datasets because of the unconstrained nature of such environments in terms of types and appearances of objects. In this paper, we take advantage of change detection for training multiple foreground detectors in an unsupervised manner. We use statistical learning techniques which exploit the use of latent parameters for selecting the best foreground model parameters for a given scenario. In essence, the main novelty of our proposed approach is to combine the where (motion segmentation) and what (learning procedure) in change detection in an unsupervised way for improving the specificity and generalization power of foreground detectors at the same time. We propose a framework based on latent support vector machines that, given a noisy initialization based on motion cues, learns the correct position, aspect ratio, and appearance of all moving objects in a particular scene. Specificity is achieved by learning the particular change detections of a given scenario, and generalization is guaranteed since our method can be applied to any possible scene and foreground object, as demonstrated in the experimental results outperforming the state-of-the-art.

Abstract: OBJECTIVES:
The aim of the study was to address the need for quantifying the global cancer time evolution magnitude from a pair of time-consecutive positron emission tomography-computed tomography (PET-CT) scans. In particular, we focus on the computation of indicators using image-processing techniques that seek to model non-Hodgkin's lymphoma (NHL) progression or response severity.
MATERIALS AND METHODS:
A total of 89 pairs of time-consecutive PET-CT scans from NHL patients were stored in a nuclear medicine station for subsequent analysis. These were classified by a consensus of nuclear medicine physicians into progressions, partial responses, mixed responses, complete responses, and relapses. The cases of each group were ordered by magnitude following visual analysis. Thereafter, a set of quantitative indicators designed to model the cancer evolution magnitude within each group were computed using semiautomatic and automatic image-processing techniques. Performance evaluation of the proposed indicators was measured by a correlation analysis with the expert-based visual analysis.
RESULTS:
The set of proposed indicators achieved Pearson's correlation results in each group with respect to the expert-based visual analysis: 80.2% in progressions, 77.1% in partial response, 68.3% in mixed response, 88.5% in complete response, and 100% in relapse. In the progression and mixed response groups, the proposed indicators outperformed the common indicators used in clinical practice [changes in metabolic tumor volume, mean, maximum, peak standardized uptake value (SUV mean, SUV max, SUV peak), and total lesion glycolysis] by more than 40%.
CONCLUSION:
Computing global indicators of NHL response using PET-CT imaging techniques offers a strong correlation with the associated expert-based visual analysis, motivating the future incorporation of such quantitative and highly observer-independent indicators in oncological decision making or treatment response evaluation scenarios.

Abstract: We propose a meta-parameter free, off-the-shelf, simple and fast unsupervised feature learning algorithm, which exploits a new way of optimizing for sparsity. Experiments on CIFAR-10, STL- 10 and UCMerced show that the method achieves the state-of-theart performance, providing discriminative features that generalize well.