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Laura Igual, Joan Carles Soliva, Antonio Hernandez, Sergio Escalera, Xavier Jimenez, Oscar Vilarroya, et al. (2011). A fully-automatic caudate nucleus segmentation of brain MRI: Application in volumetric analysis of pediatric attention-deficit/hyperactivity disorder. BEO - BioMedical Engineering Online, 10(105), 1–23.
Abstract: Background
Accurate automatic segmentation of the caudate nucleus in magnetic resonance images (MRI) of the brain is of great interest in the analysis of developmental disorders. Segmentation methods based on a single atlas or on multiple atlases have been shown to suitably localize caudate structure. However, the atlas prior information may not represent the structure of interest correctly. It may therefore be useful to introduce a more flexible technique for accurate segmentations.
Method
We present Cau-dateCut: a new fully-automatic method of segmenting the caudate nucleus in MRI. CaudateCut combines an atlas-based segmentation strategy with the Graph Cut energy-minimization framework. We adapt the Graph Cut model to make it suitable for segmenting small, low-contrast structures, such as the caudate nucleus, by defining new energy function data and boundary potentials. In particular, we exploit information concerning the intensity and geometry, and we add supervised energies based on contextual brain structures. Furthermore, we reinforce boundary detection using a new multi-scale edgeness measure.
Results
We apply the novel CaudateCut method to the segmentation of the caudate nucleus to a new set of 39 pediatric attention-deficit/hyperactivity disorder (ADHD) patients and 40 control children, as well as to a public database of 18 subjects. We evaluate the quality of the segmentation using several volumetric and voxel by voxel measures. Our results show improved performance in terms of segmentation compared to state-of-the-art approaches, obtaining a mean overlap of 80.75%. Moreover, we present a quantitative volumetric analysis of caudate abnormalities in pediatric ADHD, the results of which show strong correlation with expert manual analysis.
Conclusion
CaudateCut generates segmentation results that are comparable to gold-standard segmentations and which are reliable in the analysis of differentiating neuroanatomical abnormalities between healthy controls and pediatric ADHD.
Keywords: Brain caudate nucleus; segmentation; MRI; atlas-based strategy; Graph Cut framework
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Razieh Rastgoo, Kourosh Kiani, & Sergio Escalera. (2023). A deep co-attentive hand-based video question answering framework using multi-view skeleton. MTAP - Multimedia Tools and Applications, 82, 1401–1429.
Abstract: In this paper, we present a novel hand –based Video Question Answering framework, entitled Multi-View Video Question Answering (MV-VQA), employing the Single Shot Detector (SSD), Convolutional Neural Network (CNN), Long Short-Term Memory (LSTM), Bidirectional Encoder Representations from Transformers (BERT), and Co-Attention mechanism with RGB videos as the inputs. Our model includes three main blocks: vision, language, and attention. In the vision block, we employ a novel representation to obtain some efficient multiview features from the hand object using the combination of five 3DCNNs and one LSTM network. To obtain the question embedding, we use the BERT model in language block. Finally, we employ a co-attention mechanism on vision and language features to recognize the final answer. For the first time, we propose such a hand-based Video-QA framework including the multi-view hand skeleton features combined with the question embedding and co-attention mechanism. Our framework is capable of processing the arbitrary numbers of questions in the dataset annotations. There are different application domains for this framework. Here, as an application domain, we applied our framework to dynamic hand gesture recognition for the first time. Since the main object in dynamic hand gesture recognition is the human hand, we performed a step-by-step analysis of the hand detection and multi-view hand skeleton impact on the model performance. Evaluation results on five datasets, including two datasets in VideoQA, two datasets in dynamic hand gesture, and one dataset in hand action recognition show that MV-VQA outperforms state-of-the-art alternatives.
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Frederic Sampedro, Sergio Escalera, Anna Domenech, & Ignasi Carrio. (2014). A computational framework for cancer response assessment based on oncological PET-CT scans. CBM - Computers in Biology and Medicine, 55, 92–99.
Abstract: In this work we present a comprehensive computational framework to help in the clinical assessment of cancer response from a pair of time consecutive oncological PET-CT scans. In this scenario, the design and implementation of a supervised machine learning system to predict and quantify cancer progression or response conditions by introducing a novel feature set that models the underlying clinical context is described. Performance results in 100 clinical cases (corresponding to 200 whole body PET-CT scans) in comparing expert-based visual analysis and classifier decision making show up to 70% accuracy within a completely automatic pipeline and 90% accuracy when providing the system with expert-guided PET tumor segmentation masks.
Keywords: Computer aided diagnosis; Nuclear medicine; Machine learning; Image processing; Quantitative analysis
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