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Frederic Sampedro; Anna Domenech; Sergio Escalera |
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Obtaining quantitative global tumoral state indicators based on whole-body PET/CT scans: A breast cancer case study |
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Journal Article |
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Year |
2014 |
Publication |
Nuclear Medicine Communications |
Abbreviated Journal |
NMC |
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Volume |
35 |
Issue |
4 |
Pages |
362-371 |
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Abstract |
Objectives: In this work we address the need for the computation of quantitative global tumoral state indicators from oncological whole-body PET/computed tomography scans. The combination of such indicators with other oncological information such as tumor markers or biopsy results would prove useful in oncological decision-making scenarios.
Materials and methods: From an ordering of 100 breast cancer patients on the basis of oncological state through visual analysis by a consensus of nuclear medicine specialists, a set of numerical indicators computed from image analysis of the PET/computed tomography scan is presented, which attempts to summarize a patient’s oncological state in a quantitative manner taking into consideration the total tumor volume, aggressiveness, and spread.
Results: Results obtained by comparative analysis of the proposed indicators with respect to the experts’ evaluation show up to 87% Pearson’s correlation coefficient when providing expert-guided PET metabolic tumor volume segmentation and 64% correlation when using completely automatic image analysis techniques.
Conclusion: Global quantitative tumor information obtained by whole-body PET/CT image analysis can prove useful in clinical nuclear medicine settings and oncological decision-making scenarios. The completely automatic computation of such indicators would improve its impact as time efficiency and specialist independence would be achieved. |
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HuPBA;MILAB |
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SDE2014a |
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2444 |
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Author |
Pedro Martins; Paulo Carvalho; Carlo Gatta |
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Title |
On the completeness of feature-driven maximally stable extremal regions |
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Journal Article |
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2016 |
Publication |
Pattern Recognition Letters |
Abbreviated Journal |
PRL |
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Volume |
74 |
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Pages |
9-16 |
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Local features; Completeness; Maximally Stable Extremal Regions |
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By definition, local image features provide a compact representation of the image in which most of the image information is preserved. This capability offered by local features has been overlooked, despite being relevant in many application scenarios. In this paper, we analyze and discuss the performance of feature-driven Maximally Stable Extremal Regions (MSER) in terms of the coverage of informative image parts (completeness). This type of features results from an MSER extraction on saliency maps in which features related to objects boundaries or even symmetry axes are highlighted. These maps are intended to be suitable domains for MSER detection, allowing this detector to provide a better coverage of informative image parts. Our experimental results, which were based on a large-scale evaluation, show that feature-driven MSER have relatively high completeness values and provide more complete sets than a traditional MSER detection even when sets of similar cardinality are considered. |
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Elsevier B.V. |
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0167-8655 |
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LAMP;MILAB; |
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Admin @ si @ MCG2016 |
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2748 |
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Sergio Escalera; Oriol Pujol; Petia Radeva |
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On the Decoding Process in Ternary Error-Correcting Output Codes |
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2010 |
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IEEE on Pattern Analysis and Machine Intelligence |
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TPAMI |
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32 |
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1 |
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120–134 |
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A common way to model multiclass classification problems is to design a set of binary classifiers and to combine them. Error-correcting output codes (ECOC) represent a successful framework to deal with these type of problems. Recent works in the ECOC framework showed significant performance improvements by means of new problem-dependent designs based on the ternary ECOC framework. The ternary framework contains a larger set of binary problems because of the use of a ldquodo not carerdquo symbol that allows us to ignore some classes by a given classifier. However, there are no proper studies that analyze the effect of the new symbol at the decoding step. In this paper, we present a taxonomy that embeds all binary and ternary ECOC decoding strategies into four groups. We show that the zero symbol introduces two kinds of biases that require redefinition of the decoding design. A new type of decoding measure is proposed, and two novel decoding strategies are defined. We evaluate the state-of-the-art coding and decoding strategies over a set of UCI machine learning repository data sets and into a real traffic sign categorization problem. The experimental results show that, following the new decoding strategies, the performance of the ECOC design is significantly improved. |
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0162-8828 |
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MILAB;HUPBA |
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BCNPCL @ bcnpcl @ EPR2010b |
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1277 |
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Author |
Miguel Angel Bautista; Sergio Escalera; Oriol Pujol |
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Title |
On the Design of an ECOC-Compliant Genetic Algorithm |
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Journal Article |
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Year |
2014 |
Publication |
Pattern Recognition |
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PR |
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47 |
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2 |
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865-884 |
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Genetic Algorithms (GA) have been previously applied to Error-Correcting Output Codes (ECOC) in state-of-the-art works in order to find a suitable coding matrix. Nevertheless, none of the presented techniques directly take into account the properties of the ECOC matrix. As a result the considered search space is unnecessarily large. In this paper, a novel Genetic strategy to optimize the ECOC coding step is presented. This novel strategy redefines the usual crossover and mutation operators in order to take into account the theoretical properties of the ECOC framework. Thus, it reduces the search space and lets the algorithm to converge faster. In addition, a novel operator that is able to enlarge the code in a smart way is introduced. The novel methodology is tested on several UCI datasets and four challenging computer vision problems. Furthermore, the analysis of the results done in terms of performance, code length and number of Support Vectors shows that the optimization process is able to find very efficient codes, in terms of the trade-off between classification performance and the number of classifiers. Finally, classification performance per dichotomizer results shows that the novel proposal is able to obtain similar or even better results while defining a more compact number of dichotomies and SVs compared to state-of-the-art approaches. |
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HuPBA;MILAB |
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Admin @ si @ BEP2013 |
Serial |
2254 |
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Author |
Sergio Escalera; David Masip; Eloi Puertas; Petia Radeva; Oriol Pujol |
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Title |
Online Error-Correcting Output Codes |
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Journal Article |
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Year |
2011 |
Publication |
Pattern Recognition Letters |
Abbreviated Journal |
PRL |
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32 |
Issue |
3 |
Pages |
458-467 |
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IF JCR CCIA 1.303 2009 54/103
This article proposes a general extension of the error correcting output codes framework to the online learning scenario. As a result, the final classifier handles the addition of new classes independently of the base classifier used. In particular, this extension supports the use of both online example incremental and batch classifiers as base learners. The extension of the traditional problem independent codings one-versus-all and one-versus-one is introduced. Furthermore, two new codings are proposed, unbalanced online ECOC and a problem dependent online ECOC. This last online coding technique takes advantage of the problem data for minimizing the number of dichotomizers used in the ECOC framework while preserving a high accuracy. These techniques are validated on an online setting of 11 data sets from UCI database and applied to two real machine vision applications: traffic sign recognition and face recognition. As a result, the online ECOC techniques proposed provide a feasible and robust way for handling new classes using any base classifier. |
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Elsevier |
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North Holland |
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0167-8655 |
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MILAB;OR;HuPBA;MV |
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Admin @ si @ EMP2011 |
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1714 |
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