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Sumit K. Banchhor; Tadashi Araki; Narendra D. Londhe; Nobutaka Ikeda; Petia Radeva; Ayman El-Baz; Luca Saba; Andrew Nicolaides; Shoaib Shafique; John R. Laird; Jasjit S. Suri |
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Title  |
Five multiresolution-based calcium volume measurement techniques from coronary IVUS videos: A comparative approach |
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Journal Article |
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Year |
2016 |
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Computer Methods and Programs in Biomedicine |
Abbreviated Journal |
CMPB |
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134 |
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237-258 |
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BACKGROUND AND OBJECTIVE:
Fast intravascular ultrasound (IVUS) video processing is required for calcium volume computation during the planning phase of percutaneous coronary interventional (PCI) procedures. Nonlinear multiresolution techniques are generally applied to improve the processing time by down-sampling the video frames.
METHODS:
This paper presents four different segmentation methods for calcium volume measurement, namely Threshold-based, Fuzzy c-Means (FCM), K-means, and Hidden Markov Random Field (HMRF) embedded with five different kinds of multiresolution techniques (bilinear, bicubic, wavelet, Lanczos, and Gaussian pyramid). This leads to 20 different kinds of combinations. IVUS image data sets consisting of 38,760 IVUS frames taken from 19 patients were collected using 40 MHz IVUS catheter (Atlantis® SR Pro, Boston Scientific®, pullback speed of 0.5 mm/sec.). The performance of these 20 systems is compared with and without multiresolution using the following metrics: (a) computational time; (b) calcium volume; (c) image quality degradation ratio; and (d) quality assessment ratio.
RESULTS:
Among the four segmentation methods embedded with five kinds of multiresolution techniques, FCM segmentation combined with wavelet-based multiresolution gave the best performance. FCM and wavelet experienced the highest percentage mean improvement in computational time of 77.15% and 74.07%, respectively. Wavelet interpolation experiences the highest mean precision-of-merit (PoM) of 94.06 ± 3.64% and 81.34 ± 16.29% as compared to other multiresolution techniques for volume level and frame level respectively. Wavelet multiresolution technique also experiences the highest Jaccard Index and Dice Similarity of 0.7 and 0.8, respectively. Multiresolution is a nonlinear operation which introduces bias and thus degrades the image. The proposed system also provides a bias correction approach to enrich the system, giving a better mean calcium volume similarity for all the multiresolution-based segmentation methods. After including the bias correction, bicubic interpolation gives the largest increase in mean calcium volume similarity of 4.13% compared to the rest of the multiresolution techniques. The system is automated and can be adapted in clinical settings.
CONCLUSIONS:
We demonstrated the time improvement in calcium volume computation without compromising the quality of IVUS image. Among the 20 different combinations of multiresolution with calcium volume segmentation methods, the FCM embedded with wavelet-based multiresolution gave the best performance. |
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Admin @ si @ BAL2016 |
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2830 |
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Mariella Dimiccoli |
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Title |
Figure-ground segregation: A fully nonlocal approach |
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Journal Article |
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2016 |
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Vision Research |
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VR |
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126 |
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308-317 |
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Figure-ground segregation; Nonlocal approach; Directional linear voting; Nonlinear diffusion |
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We present a computational model that computes and integrates in a nonlocal fashion several configural cues for automatic figure-ground segregation. Our working hypothesis is that the figural status of each pixel is a nonlocal function of several geometric shape properties and it can be estimated without explicitly relying on object boundaries. The methodology is grounded on two elements: multi-directional linear voting and nonlinear diffusion. A first estimation of the figural status of each pixel is obtained as a result of a voting process, in which several differently oriented line-shaped neighborhoods vote to express their belief about the figural status of the pixel. A nonlinear diffusion process is then applied to enforce the coherence of figural status estimates among perceptually homogeneous regions. Computer simulations fit human perception and match the experimental evidence that several cues cooperate in defining figure-ground segregation. The results of this work suggest that figure-ground segregation involves feedback from cells with larger receptive fields in higher visual cortical areas. |
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Admin @ si @ Dim2016b |
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2623 |
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Simone Balocco; O. Camara; E. Vivas; T. Sola; L. Guimaraens; H. A. van Andel; C. B. Majoie; J. M. Pozo; B. H. Bijnens; Alejandro F. Frangi |
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Title |
Feasibility of Estimating Regional Mechanical Properties of Cerebral Aneurysms In Vivo |
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2010 |
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Medical Physics |
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MEDPHYS |
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37 |
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4 |
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1689–1706 |
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PURPOSE:
In this article, the authors studied the feasibility of estimating regional mechanical properties in cerebral aneurysms, integrating information extracted from imaging and physiological data with generic computational models of the arterial wall behavior.
METHODS:
A data assimilation framework was developed to incorporate patient-specific geometries into a given biomechanical model, whereas wall motion estimates were obtained from applying registration techniques to a pair of simulated MR images and guided the mechanical parameter estimation. A simple incompressible linear and isotropic Hookean model coupled with computational fluid-dynamics was employed as a first approximation for computational purposes. Additionally, an automatic clustering technique was developed to reduce the number of parameters to assimilate at the optimization stage and it considerably accelerated the convergence of the simulations. Several in silico experiments were designed to assess the influence of aneurysm geometrical characteristics and the accuracy of wall motion estimates on the mechanical property estimates. Hence, the proposed methodology was applied to six real cerebral aneurysms and tested against a varying number of regions with different elasticity, different mesh discretization, imaging resolution, and registration configurations.
RESULTS:
Several in silico experiments were conducted to investigate the feasibility of the proposed workflow, results found suggesting that the estimation of the mechanical properties was mainly influenced by the image spatial resolution and the chosen registration configuration. According to the in silico experiments, the minimal spatial resolution needed to extract wall pulsation measurements with enough accuracy to guide the proposed data assimilation framework was of 0.1 mm.
CONCLUSIONS:
Current routine imaging modalities do not have such a high spatial resolution and therefore the proposed data assimilation framework cannot currently be used on in vivo data to reliably estimate regional properties in cerebral aneurysms. Besides, it was observed that the incorporation of fluid-structure interaction in a biomechanical model with linear and isotropic material properties did not have a substantial influence in the final results. |
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BCNPCL @ bcnpcl @ BCV2010 |
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1313 |
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Carlo Gatta; Oriol Pujol; O. Rodriguez-Leor; J. M. Ferre; Petia Radeva |
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Title |
Fast Rigid Registration of Vascular Structures in IVUS Sequences |
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Journal Article |
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2009 |
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IEEE Transactions on Information Technology in Biomedicine |
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13 |
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6 |
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106-1011 |
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Intravascular ultrasound (IVUS) technology permits visualization of high-resolution images of internal vascular structures. IVUS is a unique image-guiding tool to display longitudinal view of the vessels, and estimate the length and size of vascular structures with the goal of accurate diagnosis. Unfortunately, due to pulsatile contraction and expansion of the heart, the captured images are affected by different motion artifacts that make visual inspection difficult. In this paper, we propose an efficient algorithm that aligns vascular structures and strongly reduces the saw-shaped oscillation, simplifying the inspection of longitudinal cuts; it reduces the motion artifacts caused by the displacement of the catheter in the short-axis plane and the catheter rotation due to vessel tortuosity. The algorithm prototype aligns 3.16 frames/s and clearly outperforms state-of-the-art methods with similar computational cost. The speed of the algorithm is crucial since it allows to inspect the corrected sequence during patient intervention. Moreover, we improved an indirect methodology for IVUS rigid registration algorithm evaluation. |
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1089-7771 |
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MILAB;HuPBA |
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BCNPCL @ bcnpcl @ GPL2009 |
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1250 |
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Debora Gil; Petia Radeva |
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Title |
Extending anisotropic operators to recover smooth shapes |
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2005 |
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Computer Vision and Image Understanding |
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99 |
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1 |
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110-125 |
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Contour completion; Functional extension; Differential operators; Riemmanian manifolds; Snake segmentation |
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Anisotropic differential operators are widely used in image enhancement processes. Recently, their property of smoothly extending functions to the whole image domain has begun to be exploited. Strong ellipticity of differential operators is a requirement that ensures existence of a unique solution. This condition is too restrictive for operators designed to extend image level sets: their own functionality implies that they should restrict to some vector field. The diffusion tensor that defines the diffusion operator links anisotropic processes with Riemmanian manifolds. In this context, degeneracy implies restricting diffusion to the varieties generated by the vector fields of positive eigenvalues, provided that an integrability condition is satisfied. We will use that any smooth vector field fulfills this integrability requirement to design line connection algorithms for contour completion. As application we present a segmenting strategy that assures convergent snakes whatever the geometry of the object to be modelled is. |
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1077-3142 |
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IAM;MILAB |
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IAM @ iam @ GIR2005 |
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1530 |
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