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David Rotger, Misael Rosales, Jaume Garcia, Oriol Pujol, Josefina Mauri, & Petia Radeva. (2003). Active Vessel: A New Multimedia Workstation for Intravascular Ultrasound and Angiography Fusion. Computers in Cardiology, 30, 65–68.
Abstract: AcriveVessel is a new multimedia workstation which enables the visualization, acquisition and handling of both image modalities, on- and ofline. It enables DICOM v3.0 decompression and browsing, video acquisition,repmduction and storage for IntraVascular UltraSound (IVUS) and angiograms with their corresponding ECG,automatic catheter segmentation in angiography images (using fast marching algorithm). BSpline models definition for vessel layers on IVUS images sequence and an extensively validated tool to fuse information. This approach defines the correspondence of every IVUS image with its correspondent point in the angiogram and viceversa. The 3 0 reconstruction of the NUS catheterhessel enables real distance measurements as well as threedimensional visualization showing vessel tortuosity in the space.
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Sergio Vera, Debora Gil, Antonio Lopez, & Miguel Angel Gonzalez Ballester. (2012). Multilocal Creaseness Measure. IJ - The Insight Journal.
Abstract: This document describes the implementation using the Insight Toolkit of an algorithm for detecting creases (ridges and valleys) in N-dimensional images, based on the Local Structure Tensor of the image. In addition to the filter used to calculate the creaseness image, a filter for the computation of the structure tensor is also included in this submission.
Keywords: Ridges, Valley, Creaseness, Structure Tensor, Skeleton,
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Ferran Poveda, Enric Marti, Debora Gil, Francesc Carreras, & Manel Ballester. (2012). Helical Structure of Ventricular Anatomy by Diffusion Tensor Cardiac MR Tractography. JACC - Journal of American College of Cardiology, 5(7), 754–755.
Abstract: It is widely accepted that myocardial fiber architecture plays a critical role in myocardial contractility and relaxation (1). However, there is a lack of consensus about the distribution of the myocardial fibers and their spatial arrangement in the left and right ventricles. An understanding of the cardiac architecture should benefit the ventricular functional assessment, left ventricular reconstructive surgery planning, or resynchronization therapy in heart failure. Researchers have proposed several conceptual models to describe the architecture of the heart, ranging from gross dissection to histological presentation. The cardiac mesh model (2) proposes that the myocytes are arranged longitudinally and radially change their angulation along the myocardial depth. By contrast, the helical ventricular myocardial model states that the ventricular myocardium is a continuous anatomical helical layout of myocardial fibers (1
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David Roche, Debora Gil, & Jesus Giraldo. (2013). Mechanistic analysis of the function of agonists and allosteric modulators: Reconciling two-state and operational models. BJP - British Journal of Pharmacology, 169(6), 1189–202.
Abstract: Two-state and operational models of both agonism and allosterism are compared to identify and characterize common pharmacological parameters. To account for the receptor-dependent basal response, constitutive receptor activity is considered in the operational models. By arranging two-state models as the fraction of active receptors and operational models as the fractional response relative to the maximum effect of the system, a one-by-one correspondence between parameters is found. The comparative analysis allows a better understanding of complex allosteric interactions. In particular, the inclusion of constitutive receptor activity in the operational model of allosterism allows the characterization of modulators able to lower the basal response of the system; that is, allosteric modulators with negative intrinsic efficacy. Theoretical simulations and overall goodness of fit of the models to simulated data suggest that it is feasible to apply the models to experimental data and constitute one step forward in receptor theory formalism.
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Enric Marti, J.Roncaries, Debora Gil, Aura Hernandez-Sabate, Antoni Gurgui, & Ferran Poveda. (2015). PBL On Line: A proposal for the organization, part-time monitoring and assessment of PBL group activities. JOTSE - Journal of Technology and Science Education, 87–96.
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