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Author |
Frederic Sampedro; Anna Domenech; Sergio Escalera |
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Title |
Obtaining quantitative global tumoral state indicators based on whole-body PET/CT scans: A breast cancer case study |
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Journal Article |
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Year |
2014 |
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Nuclear Medicine Communications |
Abbreviated Journal |
NMC |
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35 |
Issue |
4 |
Pages |
362-371 |
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Abstract |
Objectives: In this work we address the need for the computation of quantitative global tumoral state indicators from oncological whole-body PET/computed tomography scans. The combination of such indicators with other oncological information such as tumor markers or biopsy results would prove useful in oncological decision-making scenarios.
Materials and methods: From an ordering of 100 breast cancer patients on the basis of oncological state through visual analysis by a consensus of nuclear medicine specialists, a set of numerical indicators computed from image analysis of the PET/computed tomography scan is presented, which attempts to summarize a patient’s oncological state in a quantitative manner taking into consideration the total tumor volume, aggressiveness, and spread.
Results: Results obtained by comparative analysis of the proposed indicators with respect to the experts’ evaluation show up to 87% Pearson’s correlation coefficient when providing expert-guided PET metabolic tumor volume segmentation and 64% correlation when using completely automatic image analysis techniques.
Conclusion: Global quantitative tumor information obtained by whole-body PET/CT image analysis can prove useful in clinical nuclear medicine settings and oncological decision-making scenarios. The completely automatic computation of such indicators would improve its impact as time efficiency and specialist independence would be achieved. |
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HuPBA;MILAB |
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SDE2014a |
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2444 |
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Author |
Frederic Sampedro; Anna Domenech; Sergio Escalera; Ignasi Carrio |
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Title |
Deriving global quantitative tumor response parameters from 18F-FDG PET-CT scans in patients with non-Hodgkins lymphoma |
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Journal Article |
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Year |
2015 |
Publication |
Nuclear Medicine Communications |
Abbreviated Journal |
NMC |
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Volume |
36 |
Issue |
4 |
Pages |
328-333 |
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Abstract |
OBJECTIVES:
The aim of the study was to address the need for quantifying the global cancer time evolution magnitude from a pair of time-consecutive positron emission tomography-computed tomography (PET-CT) scans. In particular, we focus on the computation of indicators using image-processing techniques that seek to model non-Hodgkin's lymphoma (NHL) progression or response severity.
MATERIALS AND METHODS:
A total of 89 pairs of time-consecutive PET-CT scans from NHL patients were stored in a nuclear medicine station for subsequent analysis. These were classified by a consensus of nuclear medicine physicians into progressions, partial responses, mixed responses, complete responses, and relapses. The cases of each group were ordered by magnitude following visual analysis. Thereafter, a set of quantitative indicators designed to model the cancer evolution magnitude within each group were computed using semiautomatic and automatic image-processing techniques. Performance evaluation of the proposed indicators was measured by a correlation analysis with the expert-based visual analysis.
RESULTS:
The set of proposed indicators achieved Pearson's correlation results in each group with respect to the expert-based visual analysis: 80.2% in progressions, 77.1% in partial response, 68.3% in mixed response, 88.5% in complete response, and 100% in relapse. In the progression and mixed response groups, the proposed indicators outperformed the common indicators used in clinical practice [changes in metabolic tumor volume, mean, maximum, peak standardized uptake value (SUV mean, SUV max, SUV peak), and total lesion glycolysis] by more than 40%.
CONCLUSION:
Computing global indicators of NHL response using PET-CT imaging techniques offers a strong correlation with the associated expert-based visual analysis, motivating the future incorporation of such quantitative and highly observer-independent indicators in oncological decision making or treatment response evaluation scenarios. |
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Admin @ si @ SDE2015 |
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2605 |
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Author |
Eloi Puertas; Sergio Escalera; Oriol Pujol |
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Title |
Generalized Multi-scale Stacked Sequential Learning for Multi-class Classification |
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Journal Article |
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Year |
2015 |
Publication |
Pattern Analysis and Applications |
Abbreviated Journal |
PAA |
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18 |
Issue |
2 |
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247-261 |
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Stacked sequential learning; Multi-scale; Error-correct output codes (ECOC); Contextual classification |
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In many classification problems, neighbor data labels have inherent sequential relationships. Sequential learning algorithms take benefit of these relationships in order to improve generalization. In this paper, we revise the multi-scale sequential learning approach (MSSL) for applying it in the multi-class case (MMSSL). We introduce the error-correcting output codesframework in the MSSL classifiers and propose a formulation for calculating confidence maps from the margins of the base classifiers. In addition, we propose a MMSSL compression approach which reduces the number of features in the extended data set without a loss in performance. The proposed methods are tested on several databases, showing significant performance improvement compared to classical approaches. |
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Springer-Verlag |
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1433-7541 |
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HuPBA;MILAB |
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Admin @ si @ PEP2013 |
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2251 |
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Author |
Mohammad Ali Bagheri; Qigang Gao; Sergio Escalera |
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Title |
Combining Local and Global Learners in the Pairwise Multiclass Classification |
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Journal Article |
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Year |
2015 |
Publication |
Pattern Analysis and Applications |
Abbreviated Journal |
PAA |
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18 |
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4 |
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845-860 |
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Multiclass classification; Pairwise approach; One-versus-one |
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Pairwise classification is a well-known class binarization technique that converts a multiclass problem into a number of two-class problems, one problem for each pair of classes. However, in the pairwise technique, nuisance votes of many irrelevant classifiers may result in a wrong class prediction. To overcome this problem, a simple, but efficient method is proposed and evaluated in this paper. The proposed method is based on excluding some classes and focusing on the most probable classes in the neighborhood space, named Local Crossing Off (LCO). This procedure is performed by employing a modified version of standard K-nearest neighbor and large margin nearest neighbor algorithms. The LCO method takes advantage of nearest neighbor classification algorithm because of its local learning behavior as well as the global behavior of powerful binary classifiers to discriminate between two classes. Combining these two properties in the proposed LCO technique will avoid the weaknesses of each method and will increase the efficiency of the whole classification system. On several benchmark datasets of varying size and difficulty, we found that the LCO approach leads to significant improvements using different base learners. The experimental results show that the proposed technique not only achieves better classification accuracy in comparison to other standard approaches, but also is computationally more efficient for tackling classification problems which have a relatively large number of target classes. |
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Springer London |
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1433-7541 |
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HuPBA;MILAB |
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Call Number |
Admin @ si @ BGE2014 |
Serial |
2441 |
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Author |
Alejandro Cartas; Juan Marin; Petia Radeva; Mariella Dimiccoli |
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Title |
Batch-based activity recognition from egocentric photo-streams revisited |
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Journal Article |
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Year |
2018 |
Publication |
Pattern Analysis and Applications |
Abbreviated Journal |
PAA |
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Volume |
21 |
Issue |
4 |
Pages |
953–965 |
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Egocentric vision; Lifelogging; Activity recognition; Deep learning; Recurrent neural networks |
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Abstract |
Wearable cameras can gather large amounts of image data that provide rich visual information about the daily activities of the wearer. Motivated by the large number of health applications that could be enabled by the automatic recognition of daily activities, such as lifestyle characterization for habit improvement, context-aware personal assistance and tele-rehabilitation services, we propose a system to classify 21 daily activities from photo-streams acquired by a wearable photo-camera. Our approach combines the advantages of a late fusion ensemble strategy relying on convolutional neural networks at image level with the ability of recurrent neural networks to account for the temporal evolution of high-level features in photo-streams without relying on event boundaries. The proposed batch-based approach achieved an overall accuracy of 89.85%, outperforming state-of-the-art end-to-end methodologies. These results were achieved on a dataset consists of 44,902 egocentric pictures from three persons captured during 26 days in average. |
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MILAB; no proj |
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Admin @ si @ CMR2018 |
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3186 |
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