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Tadashi Araki; Nobutaka Ikeda; Nilanjan Dey; Sayan Chakraborty; Luca Saba; Dinesh Kumar; Elisa Cuadrado Godia; Xiaoyi Jiang; Ajay Gupta; Petia Radeva; John R. Laird; Andrew Nicolaides; Jasjit S. Suri |
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A comparative approach of four different image registration techniques for quantitative assessment of coronary artery calcium lesions using intravascular ultrasound |
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Journal Article |
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2015 |
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Computer Methods and Programs in Biomedicine |
Abbreviated Journal |
CMPB |
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118 |
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2 |
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158-172 |
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Admin @ si @ AID2015 |
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2640 |
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R.A.Bendezu; E.Barba; E.Burri; D.Cisternas; Carolina Malagelada; Santiago Segui; Anna Accarino; S.Quiroga; E.Monclus; I.Navazo |
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Intestinal gas content and distribution in health and in patients with functional gut symptoms |
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Journal Article |
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2015 |
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Neurogastroenterology & Motility |
Abbreviated Journal |
NEUMOT |
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27 |
Issue |
9 |
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1249-1257 |
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Abstract |
BACKGROUND:
The precise relation of intestinal gas to symptoms, particularly abdominal bloating and distension remains incompletely elucidated. Our aim was to define the normal values of intestinal gas volume and distribution and to identify abnormalities in relation to functional-type symptoms.
METHODS:
Abdominal computed tomography scans were evaluated in healthy subjects (n = 37) and in patients in three conditions: basal (when they were feeling well; n = 88), during an episode of abdominal distension (n = 82) and after a challenge diet (n = 24). Intestinal gas content and distribution were measured by an original analysis program. Identification of patients outside the normal range was performed by machine learning techniques (one-class classifier). Results are expressed as median (IQR) or mean ± SE, as appropriate.
KEY RESULTS:
In healthy subjects the gut contained 95 (71, 141) mL gas distributed along the entire lumen. No differences were detected between patients studied under asymptomatic basal conditions and healthy subjects. However, either during a spontaneous bloating episode or once challenged with a flatulogenic diet, luminal gas was found to be increased and/or abnormally distributed in about one-fourth of the patients. These patients detected outside the normal range by the classifier exhibited a significantly greater number of abnormal features than those within the normal range (3.7 ± 0.4 vs 0.4 ± 0.1; p < 0.001).
CONCLUSIONS & INFERENCES:
The analysis of a large cohort of subjects using original techniques provides unique and heretofore unavailable information on the volume and distribution of intestinal gas in normal conditions and in relation to functional gastrointestinal symptoms. |
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Admin @ si @ BBB2015 |
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2667 |
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G.Blasco; Simone Balocco; J.Puig; J.Sanchez-Gonzalez; W.Ricart; J.Daunis-I-Estadella; X.Molina; S.Pedraza; J.M.Fernandez-Real |
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Carotid pulse wave velocity by magnetic resonance imaging is increased in middle-aged subjects with the metabolic syndrome |
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Journal Article |
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2015 |
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International Journal of Cardiovascular Imaging |
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ICJI |
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31 |
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3 |
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603-612 |
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Metabolic syndrome; Arterial stiffness; Pulse wave velocity; Carotid artery; Magnetic resonance |
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Arterial pulse wave velocity (PWV), an independent predictor of cardiovascular disease, physiologically increases with age; however, growing evidence suggests metabolic syndrome (MetS) accelerates this increase. Magnetic resonance imaging (MRI) enables reliable noninvasive assessment of arterial stiffness by measuring arterial PWV in specific vascular segments. We investigated the association between the presence of MetS and its components with carotid PWV (cPWV) in asymptomatic subjects without diabetes. We assessed cPWV by MRI in 61 individuals (mean age, 55.3 ± 14.1 years; median age, 55 years): 30 with MetS and 31 controls with similar age, sex, body mass index, and LDL-cholesterol levels. The study population was dichotomized by the median age. To remove the physiological association between PWV and age, unpaired t tests and multiple regression analyses were performed using the residuals of the regression between PWV and age. cPWV was higher in middle-aged subjects with MetS than in those without (p = 0.001), but no differences were found in elder subjects (p = 0.313). cPWV was associated with diastolic blood pressure (r = 0.276, p = 0.033) and waist circumference (r = 0.268, p = 0.038). The presence of MetS was associated with increased cPWV regardless of age, sex, blood pressure, and waist (p = 0.007). The MetS components contributing independently to an increased cPWV were hypertension (p = 0.018) and hypertriglyceridemia (p = 0.002). The presence of MetS is associated with an increased cPWV in middle-aged subjects. In particular, hypertension and hypertriglyceridemia may contribute to early progression of carotid stiffness. |
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Springer Netherlands |
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1569-5794 |
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MILAB |
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no |
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Admin @ si @ BBP2015 |
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2670 |
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Lluis Garrido; M.Guerrieri; Laura Igual |
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Title |
Image Segmentation with Cage Active Contours |
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Journal Article |
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2015 |
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IEEE Transactions on Image Processing |
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TIP |
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24 |
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12 |
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5557 - 5566 |
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Level sets; Mean value coordinates; Parametrized active contours; level sets; mean value coordinates |
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In this paper, we present a framework for image segmentation based on parametrized active contours. The evolving contour is parametrized according to a reduced set of control points that form a closed polygon and have a clear visual interpretation. The parametrization, called mean value coordinates, stems from the techniques used in computer graphics to animate virtual models. Our framework allows to easily formulate region-based energies to segment an image. In particular, we present three different local region-based energy terms: 1) the mean model; 2) the Gaussian model; 3) and the histogram model. We show the behavior of our method on synthetic and real images and compare the performance with state-of-the-art level set methods. |
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1057-7149 |
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MILAB |
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Admin @ si @ GGI2015 |
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2673 |
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Author |
Jean-Pascal Jacob; Mariella Dimiccoli; Lionel Moisan |
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Title |
Active skeleton for bacteria modeling |
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Journal Article |
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Year |
2016 |
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Computer Methods in Biomechanics and Biomedical Engineering: Imaging and Visualization |
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CMBBE |
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5 |
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4 |
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274-286 |
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Bacteria modelling; medial axis; active contours; active skeleton; shape contraints |
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The investigation of spatio-temporal dynamics of bacterial cells and their molecular components requires automated image analysis tools to track cell shape properties and molecular component locations inside the cells. In the study of bacteria aging, the molecular components of interest are protein aggregates accumulated near bacteria boundaries. This particular location makes very ambiguous the correspondence between aggregates and cells, since computing accurately bacteria boundaries in phase-contrast time-lapse imaging is a challenging task. This paper proposes an active skeleton formulation for bacteria modeling which provides several advantages: an easy computation of shape properties (perimeter, length, thickness, orientation), an improved boundary accuracy in noisy images, and a natural bacteria-centered coordinate system that permits the intrinsic location of molecular components inside the cell. Starting from an initial skeleton estimate, the medial axis of the bacterium is obtained by minimizing an energy function which incorporates bacteria shape constraints. Experimental results on biological images and comparative evaluation of the performances validate the proposed approach for modeling cigar-shaped bacteria like Escherichia coli. The Image-J plugin of the proposed method can be found online at this http URL |
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Admin @ si @ JDM2016 |
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2711 |
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