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Tadashi Araki; Sumit K. Banchhor; Narendra D. Londhe; Nobutaka Ikeda; Petia Radeva; Devarshi Shukla; Luca Saba; Antonella Balestrieri; Andrew Nicolaides; Shoaib Shafique; John R. Laird; Jasjit S. Suri |
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Title |
Reliable and Accurate Calcium Volume Measurement in Coronary Artery Using Intravascular Ultrasound Videos |
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Year |
2016 |
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Journal of Medical Systems |
Abbreviated Journal |
JMS |
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40 |
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3 |
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51:1-51:20 |
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Interventional cardiology; Atherosclerosis; Coronary arteries; IVUS; calcium volume; Soft computing; Performance Reliability; Accuracy |
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Quantitative assessment of calcified atherosclerotic volume within the coronary artery wall is vital for cardiac interventional procedures. The goal of this study is to automatically measure the calcium volume, given the borders of coronary vessel wall for all the frames of the intravascular ultrasound (IVUS) video. Three soft computing fuzzy classification techniques were adapted namely Fuzzy c-Means (FCM), K-means, and Hidden Markov Random Field (HMRF) for automated segmentation of calcium regions and volume computation. These methods were benchmarked against previously developed threshold-based method. IVUS image data sets (around 30,600 IVUS frames) from 15 patients were collected using 40 MHz IVUS catheter (Atlantis® SR Pro, Boston Scientific®, pullback speed of 0.5 mm/s). Calcium mean volume for FCM, K-means, HMRF and threshold-based method were 37.84 ± 17.38 mm3, 27.79 ± 10.94 mm3, 46.44 ± 19.13 mm3 and 35.92 ± 16.44 mm3 respectively. Cross-correlation, Jaccard Index and Dice Similarity were highest between FCM and threshold-based method: 0.99, 0.92 ± 0.02 and 0.95 + 0.02 respectively. Student’s t-test, z-test and Wilcoxon-test are also performed to demonstrate consistency, reliability and accuracy of the results. Given the vessel wall region, the system reliably and automatically measures the calcium volume in IVUS videos. Further, we validated our system against a trained expert using scoring: K-means showed the best performance with an accuracy of 92.80 %. Out procedure and protocol is along the line with method previously published clinically. |
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MILAB; |
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no |
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Admin @ si @ ABL2016 |
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2729 |
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Mariella Dimiccoli; Jean-Pascal Jacob; Lionel Moisan |
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Title |
Particle detection and tracking in fluorescence time-lapse imaging: a contrario approach |
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Journal Article |
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Year |
2016 |
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Journal of Machine Vision and Applications |
Abbreviated Journal |
MVAP |
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27 |
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511-527 |
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particle detection; particle tracking; a-contrario approach; time-lapse fluorescence imaging |
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In this work, we propose a probabilistic approach for the detection and the
tracking of particles on biological images. In presence of very noised and poor
quality data, particles and trajectories can be characterized by an a-contrario
model, that estimates the probability of observing the structures of interest
in random data. This approach, first introduced in the modeling of human visual
perception and then successfully applied in many image processing tasks, leads
to algorithms that do not require a previous learning stage, nor a tedious
parameter tuning and are very robust to noise. Comparative evaluations against
a well established baseline show that the proposed approach outperforms the
state of the art. |
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MILAB; |
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Admin @ si @ DJM2016 |
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2735 |
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Maedeh Aghaei; Mariella Dimiccoli; Petia Radeva |
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Multi-face tracking by extended bag-of-tracklets in egocentric photo-streams |
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2016 |
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Computer Vision and Image Understanding |
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CVIU |
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149 |
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146-156 |
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Wearable cameras offer a hands-free way to record egocentric images of daily experiences, where social events are of special interest. The first step towards detection of social events is to track the appearance of multiple persons involved in them. In this paper, we propose a novel method to find correspondences of multiple faces in low temporal resolution egocentric videos acquired through a wearable camera. This kind of photo-stream imposes additional challenges to the multi-tracking problem with respect to conventional videos. Due to the free motion of the camera and to its low temporal resolution, abrupt changes in the field of view, in illumination condition and in the target location are highly frequent. To overcome such difficulties, we propose a multi-face tracking method that generates a set of tracklets through finding correspondences along the whole sequence for each detected face and takes advantage of the tracklets redundancy to deal with unreliable ones. Similar tracklets are grouped into the so called extended bag-of-tracklets (eBoT), which is aimed to correspond to a specific person. Finally, a prototype tracklet is extracted for each eBoT, where the occurred occlusions are estimated by relying on a new measure of confidence. We validated our approach over an extensive dataset of egocentric photo-streams and compared it to state of the art methods, demonstrating its effectiveness and robustness. |
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MILAB; |
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Admin @ si @ ADR2016b |
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2742 |
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Author |
Mariella Dimiccoli |
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Title |
Fundamentals of cone regression |
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2016 |
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Journal of Statistics Surveys |
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10 |
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53-99 |
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cone regression; linear complementarity problems; proximal operators. |
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Cone regression is a particular case of quadratic programming that minimizes a weighted sum of squared residuals under a set of linear inequality constraints. Several important statistical problems such as isotonic, concave regression or ANOVA under partial orderings, just to name a few, can be considered as particular instances of the cone regression problem. Given its relevance in Statistics, this paper aims to address the fundamentals of cone regression from a theoretical and practical point of view. Several formulations of the cone regression problem are considered and, focusing on the particular case of concave regression as an example, several algorithms are analyzed and compared both qualitatively and quantitatively through numerical simulations. Several improvements to enhance numerical stability and bound the computational cost are proposed. For each analyzed algorithm, the pseudo-code and its corresponding code in Matlab are provided. The results from this study demonstrate that the choice of the optimization approach strongly impacts the numerical performances. It is also shown that methods are not currently available to solve efficiently cone regression problems with large dimension (more than many thousands of points). We suggest further research to fill this gap by exploiting and adapting classical multi-scale strategy to compute an approximate solution. |
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1935-7516 |
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MILAB; |
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Admin @ si @Dim2016a |
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2783 |
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Author |
J.P. Jacob; Mariella Dimiccoli; L. Moisan |
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Active skeleton for bacteria modelling |
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2017 |
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Computer Methods in Biomechanics and Biomedical Engineering: Imaging and Visualization |
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CMBBE |
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5 |
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4 |
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274-286 |
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The investigation of spatio-temporal dynamics of bacterial cells and their molecular components requires automated image analysis tools to track cell shape properties and molecular component locations inside the cells. In the study of bacteria aging, the molecular components of interest are protein aggregates accumulated near bacteria boundaries. This particular location makes very ambiguous the correspondence between aggregates and cells, since computing accurately bacteria boundaries in phase-contrast time-lapse imaging is a challenging task. This paper proposes an active skeleton formulation for bacteria modelling which provides several advantages: an easy computation of shape properties (perimeter, length, thickness and orientation), an improved boundary accuracy in noisy images and a natural bacteria-centred coordinate system that permits the intrinsic location of molecular components inside the cell. Starting from an initial skeleton estimate, the medial axis of the bacterium is obtained by minimising an energy function which incorporates bacteria shape constraints. Experimental results on biological images and comparative evaluation of the performances validate the proposed approach for modelling cigar-shaped bacteria like Escherichia coli. The Image-J plugin of the proposed method can be found online at http://fluobactracker.inrialpes.fr. |
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Taylor & Francis Group |
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MILAB; |
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Admin @ si @JDM2017 |
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2784 |
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