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Carolina Malagelada, F.De Lorio, Santiago Segui, S. Mendez, Michal Drozdzal, Jordi Vitria, et al. (2012). Functional gut disorders or disordered gut function? Small bowel dysmotility evidenced by an original technique. NEUMOT - Neurogastroenterology & Motility, 24(3), 223–230.
Abstract: JCR Impact Factor 2010: 3.349
Background This study aimed to determine the proportion of cases with abnormal intestinal motility among patients with functional bowel disorders. To this end, we applied an original method, previously developed in our laboratory, for analysis of endoluminal images obtained by capsule endoscopy. This novel technology is based on computer vision and machine learning techniques.
Methods The endoscopic capsule (Pillcam SB1; Given Imaging, Yokneam, Israel) was administered to 80 patients with functional bowel disorders and 70 healthy subjects. Endoluminal image analysis was performed with a computer vision program developed for the evaluation of contractile events (luminal occlusions and radial wrinkles), non-contractile patterns (open tunnel and smooth wall patterns), type of content (secretions, chyme) and motion of wall and contents. Normality range and discrimination of abnormal cases were established by a machine learning technique. Specifically, an iterative classifier (one-class support vector machine) was applied in a random population of 50 healthy subjects as a training set and the remaining subjects (20 healthy subjects and 80 patients) as a test set.
Key Results The classifier identified as abnormal 29% of patients with functional diseases of the bowel (23 of 80), and as normal 97% of healthy subjects (68 of 70) (P < 0.05 by chi-squared test). Patients identified as abnormal clustered in two groups, which exhibited either a hyper- or a hypodynamic motility pattern. The motor behavior was unrelated to clinical features.
Conclusions & Inferences With appropriate methodology, abnormal intestinal motility can be demonstrated in a significant proportion of patients with functional bowel disorders, implying a pathologic disturbance of gut physiology.
Keywords: capsule endoscopy;computer vision analysis;machine learning technique;small bowel motility
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Carolina Malagelada, Michal Drozdzal, Santiago Segui, Sara Mendez, Jordi Vitria, Petia Radeva, et al. (2015). Classification of functional bowel disorders by objective physiological criteria based on endoluminal image analysis. AJPGI - American Journal of Physiology-Gastrointestinal and Liver Physiology, 309(6), G413–G419.
Abstract: We have previously developed an original method to evaluate small bowel motor function based on computer vision analysis of endoluminal images obtained by capsule endoscopy. Our aim was to demonstrate intestinal motor abnormalities in patients with functional bowel disorders by endoluminal vision analysis. Patients with functional bowel disorders (n = 205) and healthy subjects (n = 136) ingested the endoscopic capsule (Pillcam-SB2, Given-Imaging) after overnight fast and 45 min after gastric exit of the capsule a liquid meal (300 ml, 1 kcal/ml) was administered. Endoluminal image analysis was performed by computer vision and machine learning techniques to define the normal range and to identify clusters of abnormal function. After training the algorithm, we used 196 patients and 48 healthy subjects, completely naive, as test set. In the test set, 51 patients (26%) were detected outside the normal range (P < 0.001 vs. 3 healthy subjects) and clustered into hypo- and hyperdynamic subgroups compared with healthy subjects. Patients with hypodynamic behavior (n = 38) exhibited less luminal closure sequences (41 ± 2% of the recording time vs. 61 ± 2%; P < 0.001) and more static sequences (38 ± 3 vs. 20 ± 2%; P < 0.001); in contrast, patients with hyperdynamic behavior (n = 13) had an increased proportion of luminal closure sequences (73 ± 4 vs. 61 ± 2%; P = 0.029) and more high-motion sequences (3 ± 1 vs. 0.5 ± 0.1%; P < 0.001). Applying an original methodology, we have developed a novel classification of functional gut disorders based on objective, physiological criteria of small bowel function.
Keywords: capsule endoscopy; computer vision analysis; functional bowel disorders; intestinal motility; machine learning
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Hugo Jair Escalante, Victor Ponce, Sergio Escalera, Xavier Baro, Alicia Morales-Reyes, & Jose Martinez-Carranza. (2017). Evolving weighting schemes for the Bag of Visual Words. Neural Computing and Applications - Neural Computing and Applications, 28(5), 925–939.
Abstract: The Bag of Visual Words (BoVW) is an established representation in computer vision. Taking inspiration from text mining, this representation has proved
to be very effective in many domains. However, in most cases, standard term-weighting schemes are adopted (e.g.,term-frequency or TF-IDF). It remains open the question of whether alternative weighting schemes could boost the
performance of methods based on BoVW. More importantly, it is unknown whether it is possible to automatically learn and determine effective weighting schemes from
scratch. This paper brings some light into both of these unknowns. On the one hand, we report an evaluation of the most common weighting schemes used in text mining, but rarely used in computer vision tasks. Besides, we propose an evolutionary algorithm capable of automatically learning weighting schemes for computer vision problems. We report empirical results of an extensive study in several computer vision problems. Results show the usefulness of the proposed method.
Keywords: Bag of Visual Words; Bag of features; Genetic programming; Term-weighting schemes; Computer vision
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Jorge Bernal, Aymeric Histace, Marc Masana, Quentin Angermann, Cristina Sanchez Montes, Cristina Rodriguez de Miguel, et al. (2019). GTCreator: a flexible annotation tool for image-based datasets. IJCAR - International Journal of Computer Assisted Radiology and Surgery, 14(2), 191–201.
Abstract: Abstract Purpose: Methodology evaluation for decision support systems for health is a time consuming-task. To assess performance of polyp detection
methods in colonoscopy videos, clinicians have to deal with the annotation
of thousands of images. Current existing tools could be improved in terms of
exibility and ease of use. Methods:We introduce GTCreator, a exible annotation tool for providing image and text annotations to image-based datasets.
It keeps the main basic functionalities of other similar tools while extending
other capabilities such as allowing multiple annotators to work simultaneously
on the same task or enhanced dataset browsing and easy annotation transfer aiming to speed up annotation processes in large datasets. Results: The
comparison with other similar tools shows that GTCreator allows to obtain
fast and precise annotation of image datasets, being the only one which offers
full annotation editing and browsing capabilites. Conclusions: Our proposed
annotation tool has been proven to be efficient for large image dataset annota-
tion, as well as showing potential of use in other stages of method evaluation
such as experimental setup or results analysis.
Keywords: Annotation tool; Validation Framework; Benchmark; Colonoscopy; Evaluation
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Petia Radeva, Judit Martinez, A. Tovar, X. Binefa, Jordi Vitria, & Juan J. Villanueva. (1999). CORKIDENT: an automatic vision system for real-time inspection of natural products.
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