Abstract: BACKGROUND : Artificial intelligence (AI) research in colonoscopy is progressing rapidly but widespread clinical implementation is not yet a reality. We aimed to identify the top implementation research priorities. METHODS : An established modified Delphi approach for research priority setting was used. Fifteen international experts, including endoscopists and translational computer scientists/engineers, from nine countries participated in an online survey over 9 months. Questions related to AI implementation in colonoscopy were generated as a long-list in the first round, and then scored in two subsequent rounds to identify the top 10 research questions. RESULTS : The top 10 ranked questions were categorized into five themes. Theme 1: clinical trial design/end points (4 questions), related to optimum trial designs for polyp detection and characterization, determining the optimal end points for evaluation of AI, and demonstrating impact on interval cancer rates. Theme 2: technological developments (3 questions), including improving detection of more challenging and advanced lesions, reduction of false-positive rates, and minimizing latency. Theme 3: clinical adoption/integration (1 question), concerning the effective combination of detection and characterization into one workflow. Theme 4: data access/annotation (1 question), concerning more efficient or automated data annotation methods to reduce the burden on human experts. Theme 5: regulatory approval (1 question), related to making regulatory approval processes more efficient. CONCLUSIONS : This is the first reported international research priority setting exercise for AI in colonoscopy. The study findings should be used as a framework to guide future research with key stakeholders to accelerate the clinical implementation of AI in endoscopy.

Abstract: IF = 3.32
Many facial-analysis approaches rely on robust and accurate automatic facial landmarking to correctly function. In this paper, we describe a statistical method for automatic facial-landmark localization. Our landmarking relies on a parsimonious mixture model of Gabor wavelet features, computed in coarse-to-fine fashion and complemented with a shape prior. We assess the accuracy and the robustness of the proposed approach in extensive cross-database conditions conducted on four face data sets (Face Recognition Grand Challenge, Cohn-Kanade, Bosphorus, and BioID). Our method has 99.33% accuracy on the Bosphorus database and 97.62% accuracy on the BioID database on the average, which improves the state of the art. We show that the method is not significantly affected by low-resolution images, small rotations, facial expressions, and natural occlusions such as beard and mustache. We further test the goodness of the landmarks in a facial expression recognition application and report landmarking-induced improvement over baseline on two separate databases for video-based expression recognition (Cohn-Kanade and BU-4DFE).

Abstract: Impact factor 2010: 2.92
Impact factor 2011/12?: 3.32
Head pose and eye location for gaze estimation have been separately studied in numerous works in the literature. Previous research shows that satisfactory accuracy in head pose and eye location estimation can be achieved in constrained settings. However, in the presence of nonfrontal faces, eye locators are not adequate to accurately locate the center of the eyes. On the other hand, head pose estimation techniques are able to deal with these conditions; hence, they may be suited to enhance the accuracy of eye localization. Therefore, in this paper, a hybrid scheme is proposed to combine head pose and eye location information to obtain enhanced gaze estimation. To this end, the transformation matrix obtained from the head pose is used to normalize the eye regions, and in turn, the transformation matrix generated by the found eye location is used to correct the pose estimation procedure. The scheme is designed to enhance the accuracy of eye location estimations, particularly in low-resolution videos, to extend the operative range of the eye locators, and to improve the accuracy of the head pose tracker. These enhanced estimations are then combined to obtain a novel visual gaze estimation system, which uses both eye location and head information to refine the gaze estimates. From the experimental results, it can be derived that the proposed unified scheme improves the accuracy of eye estimations by 16% to 23%. Furthermore, it considerably extends its operating range by more than 15° by overcoming the problems introduced by extreme head poses. Moreover, the accuracy of the head pose tracker is improved by 12% to 24%. Finally, the experimentation on the proposed combined gaze estimation system shows that it is accurate (with a mean error between 2° and 5°) and that it can be used in cases where classic approaches would fail without imposing restraints on the position of the head.