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Giuseppe Pezzano, Vicent Ribas Ripoll, & Petia Radeva. (2021). CoLe-CNN: Context-learning convolutional neural network with adaptive loss function for lung nodule segmentation. CMPB - Computer Methods and Programs in Biomedicine, 198, 105792.
Abstract: Background and objective:An accurate segmentation of lung nodules in computed tomography images is a crucial step for the physical characterization of the tumour. Being often completely manually accomplished, nodule segmentation turns to be a tedious and time-consuming procedure and this represents a high obstacle in clinical practice. In this paper, we propose a novel Convolutional Neural Network for nodule segmentation that combines a light and efficient architecture with innovative loss function and segmentation strategy. Methods:In contrast to most of the standard end-to-end architectures for nodule segmentation, our network learns the context of the nodules by producing two masks representing all the background and secondary-important elements in the Computed Tomography scan. The nodule is detected by subtracting the context from the original scan image. Additionally, we introduce an asymmetric loss function that automatically compensates for potential errors in the nodule annotations. We trained and tested our Neural Network on the public LIDC-IDRI database, compared it with the state of the art and run a pseudo-Turing test between four radiologists and the network. Results:The results proved that the behaviour of the algorithm is very near to the human performance and its segmentation masks are almost indistinguishable from the ones made by the radiologists. Our method clearly outperforms the state of the art on CT nodule segmentation in terms of F1 score and IoU of and respectively. Conclusions: The main structure of the network ensures all the properties of the UNet architecture, while the Multi Convolutional Layers give a more accurate pattern recognition. The newly adopted solutions also increase the details on the border of the nodule, even under the noisiest conditions. This method can be applied now for single CT slice nodule segmentation and it represents a starting point for the future development of a fully automatic 3D segmentation software.
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Giuseppe Pezzano, Oliver Diaz, Vicent Ribas Ripoll, & Petia Radeva. (2021). CoLe-CNN+: Context learning – Convolutional neural network for COVID-19-Ground-Glass-Opacities detection and segmentation. CBM - Computers in Biology and Medicine, 136, 104689.
Abstract: The most common tool for population-wide COVID-19 identification is the Reverse Transcription-Polymerase Chain Reaction test that detects the presence of the virus in the throat (or sputum) in swab samples. This test has a sensitivity between 59% and 71%. However, this test does not provide precise information regarding the extension of the pulmonary infection. Moreover, it has been proven that through the reading of a computed tomography (CT) scan, a clinician can provide a more complete perspective of the severity of the disease. Therefore, we propose a comprehensive system for fully-automated COVID-19 detection and lesion segmentation from CT scans, powered by deep learning strategies to support decision-making process for the diagnosis of COVID-19.
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Gerard Canal, Sergio Escalera, & Cecilio Angulo. (2016). A Real-time Human-Robot Interaction system based on gestures for assistive scenarios. CVIU - Computer Vision and Image Understanding, 149, 65–77.
Abstract: Natural and intuitive human interaction with robotic systems is a key point to develop robots assisting people in an easy and effective way. In this paper, a Human Robot Interaction (HRI) system able to recognize gestures usually employed in human non-verbal communication is introduced, and an in-depth study of its usability is performed. The system deals with dynamic gestures such as waving or nodding which are recognized using a Dynamic Time Warping approach based on gesture specific features computed from depth maps. A static gesture consisting in pointing at an object is also recognized. The pointed location is then estimated in order to detect candidate objects the user may refer to. When the pointed object is unclear for the robot, a disambiguation procedure by means of either a verbal or gestural dialogue is performed. This skill would lead to the robot picking an object in behalf of the user, which could present difficulties to do it by itself. The overall system — which is composed by a NAO and Wifibot robots, a KinectTM v2 sensor and two laptops — is firstly evaluated in a structured lab setup. Then, a broad set of user tests has been completed, which allows to assess correct performance in terms of recognition rates, easiness of use and response times.
Keywords: Gesture recognition; Human Robot Interaction; Dynamic Time Warping; Pointing location estimation
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G.Blasco, Simone Balocco, J.Puig, J.Sanchez-Gonzalez, W.Ricart, J.Daunis-I-Estadella, et al. (2015). Carotid pulse wave velocity by magnetic resonance imaging is increased in middle-aged subjects with the metabolic syndrome. ICJI - International Journal of Cardiovascular Imaging, 31(3), 603–612.
Abstract: Arterial pulse wave velocity (PWV), an independent predictor of cardiovascular disease, physiologically increases with age; however, growing evidence suggests metabolic syndrome (MetS) accelerates this increase. Magnetic resonance imaging (MRI) enables reliable noninvasive assessment of arterial stiffness by measuring arterial PWV in specific vascular segments. We investigated the association between the presence of MetS and its components with carotid PWV (cPWV) in asymptomatic subjects without diabetes. We assessed cPWV by MRI in 61 individuals (mean age, 55.3 ± 14.1 years; median age, 55 years): 30 with MetS and 31 controls with similar age, sex, body mass index, and LDL-cholesterol levels. The study population was dichotomized by the median age. To remove the physiological association between PWV and age, unpaired t tests and multiple regression analyses were performed using the residuals of the regression between PWV and age. cPWV was higher in middle-aged subjects with MetS than in those without (p = 0.001), but no differences were found in elder subjects (p = 0.313). cPWV was associated with diastolic blood pressure (r = 0.276, p = 0.033) and waist circumference (r = 0.268, p = 0.038). The presence of MetS was associated with increased cPWV regardless of age, sex, blood pressure, and waist (p = 0.007). The MetS components contributing independently to an increased cPWV were hypertension (p = 0.018) and hypertriglyceridemia (p = 0.002). The presence of MetS is associated with an increased cPWV in middle-aged subjects. In particular, hypertension and hypertriglyceridemia may contribute to early progression of carotid stiffness.
Keywords: Metabolic syndrome; Arterial stiffness; Pulse wave velocity; Carotid artery; Magnetic resonance
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G. Zahnd, Simone Balocco, A. Serusclat, P. Moulin, M. Orkisz, & D. Vray. (2015). Progressive attenuation of the longitudinal kinetics in the common carotid artery: preliminary in vivo assessment Ultrasound in Medicine and Biology. UMB - Ultrasound in Medicine and Biology, 41(1), 339–345.
Abstract: Longitudinal kinetics (LOKI) of the arterial wall consists of the shearing motion of the intima-media complex over the adventitia layer in the direction parallel to the blood flow during the cardiac cycle. The aim of this study was to investigate the local variability of LOKI amplitude along the length of the vessel. By use of a previously validated motion-estimation framework, 35 in vivo longitudinal B-mode ultrasound cine loops of healthy common carotid arteries were analyzed. Results indicated that LOKI amplitude is progressively attenuated along the length of the artery, as it is larger in regions located on the proximal side of the image (i.e., toward the heart) and smaller in regions located on the distal side of the image (i.e., toward the head), with an average attenuation coefficient of -2.5 ± 2.0%/mm. Reported for the first time in this study, this phenomenon is likely to be of great importance in improving understanding of atherosclerosis mechanisms, and has the potential to be a novel index of arterial stiffness.
Keywords: Arterial stiffness; Atherosclerosis; Common carotid artery; Longitudinal kinetics; Motion tracking; Ultrasound imaging
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