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Author
Marta Diez-Ferrer; Debora Gil; Cristian Tebe; Carles Sanchez
Title
Positive Airway Pressure to Enhance Computed Tomography Imaging for Airway Segmentation for Virtual Bronchoscopic Navigation
Type
Journal Article
Year
2018
Publication
Respiration
Abbreviated Journal
RES
Volume
96
Issue
6
Pages
525-534
Keywords
Multidetector computed tomography; Bronchoscopy; Continuous positive airway pressure; Image enhancement; Virtual bronchoscopic navigation
Abstract
Abstract
RATIONALE:
Virtual bronchoscopic navigation (VBN) guidance to peripheral pulmonary lesions is often limited by insufficient segmentation of the peripheral airways.
OBJECTIVES:
To test the effect of applying positive airway pressure (PAP) during CT acquisition to improve segmentation, particularly at end-expiration.
METHODS:
CT acquisitions in inspiration and expiration with 4 PAP protocols were recorded prospectively and compared to baseline inspiratory acquisitions in 20 patients. The 4 protocols explored differences between devices (flow vs. turbine), exposures (within seconds vs. 15-min) and pressure levels (10 vs. 14 cmH2O). Segmentation quality was evaluated with the number of airways and number of endpoints reached. A generalized mixed-effects model explored the estimated effect of each protocol.
MEASUREMENTS AND MAIN RESULTS:
Patient characteristics and lung function did not significantly differ between protocols. Compared to baseline inspiratory acquisitions, expiratory acquisitions after 15 min of 14 cmH2O PAP segmented 1.63-fold more airways (95% CI 1.07-2.48; p = 0.018) and reached 1.34-fold more endpoints (95% CI 1.08-1.66; p = 0.004). Inspiratory acquisitions performed immediately under 10 cmH2O PAP reached 1.20-fold (95% CI 1.09-1.33; p < 0.001) more endpoints; after 15 min the increase was 1.14-fold (95% CI 1.05-1.24; p < 0.001).
CONCLUSIONS:
CT acquisitions with PAP segment more airways and reach more endpoints than baseline inspiratory acquisitions. The improvement is particularly evident at end-expiration after 15 min of 14 cmH2O PAP. Further studies must confirm that the improvement increases diagnostic yield when using VBN to evaluate peripheral pulmonary lesions.
Address
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Publisher
Place of Publication
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Summary Language
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Series Editor
Series Title
Abbreviated Series Title
Series Volume
Series Issue
Edition
ISSN
ISBN
Medium
Area
Expedition
Conference
Notes
IAM; 600.145
Approved
no
Call Number
Admin @ si @ DGT2018
Serial
3135
Permanent link to this record
Author
Debora Gil; Antonio Esteban Lansaque; Agnes Borras; Carles Sanchez
Title
Enhancing virtual bronchoscopy with intra-operative data using a multi-objective GAN
Type
Journal Article
Year
2019
Publication
International Journal of Computer Assisted Radiology and Surgery
Abbreviated Journal
IJCAR
Volume
7
Issue
1
Pages
Keywords
Abstract
This manuscript has been withdrawn by bioRxiv due to upload of an incorrect version of the manuscript by the authors. Therefore, this manuscript should not be cited as reference for this project.
Address
Corporate Author
Thesis
Publisher
Place of Publication
Editor
Language
Summary Language
Original Title
Series Editor
Series Title
Abbreviated Series Title
Series Volume
Series Issue
Edition
ISSN
ISBN
Medium
Area
Expedition
Conference
Notes
IAM; 600.139; 600.145
Approved
no
Call Number
Admin @ si @ GEB2019
Serial
3307
Permanent link to this record
Author
Debora Gil; Carles Sanchez; Agnes Borras; Marta Diez-Ferrer; Antoni Rosell
Title
Segmentation of Distal Airways using Structural Analysis
Type
Journal Article
Year
2019
Publication
PloS one
Abbreviated Journal
Plos
Volume
14
Issue
12
Pages
Keywords
Abstract
Segmentation of airways in Computed Tomography (CT) scans is a must for accurate support of diagnosis and intervention of many pulmonary disorders. In particular, lung cancer diagnosis would benefit from segmentations reaching most distal airways. We present a method that combines descriptors of bronchi local appearance and graph global structural analysis to fine-tune thresholds on the descriptors adapted for each bronchial level. We have compared our method to the top performers of the EXACT09 challenge and to a commercial software for biopsy planning evaluated in an own-collected data-base of high resolution CT scans acquired under different breathing conditions. Results on EXACT09 data show that our method provides a high leakage reduction with minimum loss in airway detection. Results on our data-base show the reliability across varying breathing conditions and a competitive performance for biopsy planning compared to a commercial solution.
Address
Corporate Author
Thesis
Publisher
Place of Publication
Editor
Language
Summary Language
Original Title
Series Editor
Series Title
Abbreviated Series Title
Series Volume
Series Issue
Edition
ISSN
ISBN
Medium
Area
Expedition
Conference
Notes
IAM; 600.139; 600.145
Approved
no
Call Number
Admin @ si @ GSB2019
Serial
3357
Permanent link to this record
Author
Debora Gil; Antonio Esteban Lansaque; Agnes Borras; Esmitt Ramirez; Carles Sanchez
Title
Intraoperative Extraction of Airways Anatomy in VideoBronchoscopy
Type
Journal Article
Year
2020
Publication
IEEE Access
Abbreviated Journal
ACCESS
Volume
8
Issue
Pages
159696 - 159704
Keywords
Abstract
A main bottleneck in bronchoscopic biopsy sampling is to efficiently reach the lesion navigating across bronchial levels. Any guidance system should be able to localize the scope position during the intervention with minimal costs and alteration of clinical protocols. With the final goal of an affordable image-based guidance, this work presents a novel strategy to extract and codify the anatomical structure of bronchi, as well as, the scope navigation path from videobronchoscopy. Experiments using interventional data show that our method accurately identifies the bronchial structure. Meanwhile, experiments using simulated data verify that the extracted navigation path matches the 3D route.
Address
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Thesis
Publisher
Place of Publication
Editor
Language
Summary Language
Original Title
Series Editor
Series Title
Abbreviated Series Title
Series Volume
Series Issue
Edition
ISSN
ISBN
Medium
Area
Expedition
Conference
Notes
IAM; 600.139; 600.145
Approved
no
Call Number
Admin @ si @ GEB2020
Serial
3467
Permanent link to this record
Author
Guillermo Torres; Debora Gil
Title
A multi-shape loss function with adaptive class balancing for the segmentation of lung structures
Type
Journal Article
Year
2020
Publication
International Journal of Computer Assisted Radiology and Surgery
Abbreviated Journal
IJCAR
Volume
15
Issue
1
Pages
S154-55
Keywords
Abstract
Address
Corporate Author
Thesis
Publisher
Place of Publication
Editor
Language
Summary Language
Original Title
Series Editor
Series Title
Abbreviated Series Title
Series Volume
Series Issue
Edition
ISSN
ISBN
Medium
Area
Expedition
Conference
Notes
IAM
Approved
no
Call Number
Admin @ si @ ToG2020
Serial
3590
Permanent link to this record
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