Abstract: Motion perception is an amazing innate ability of the creatures on the planet. This adroitness entails a functional advantage that enables species to compete better in the wild. The motion perception ability is usually employed at different levels, allowing from the simplest interaction with the ’physis’ up to the most transcendental survival tasks. Among the five classical perception system , vision is the most widely used in the motion perception field. Millions years of evolution have led to a highly specialized visual system in humans, which is characterized by a tremendous accuracy as well as an extraordinary robustness. Although humans and an immense diversity of species can distinguish moving object with a seeming simplicity, it has proven to be a difficult and non trivial problem from a computational perspective. In the field of Computer Vision, the detection of moving objects is a challenging and fundamental research area. This can be referred to as the ’origin’ of vast and numerous vision-based research sub-areas. Nevertheless, from the bottom to the top of this hierarchical analysis, the foundations still relies on when and where motion has occurred in an image. Pixels corresponding to moving objects in image sequences can be identified by measuring changes in their values. However, a pixel’s value (representing a combination of color and brightness) could also vary due to other factors such as: variation in scene illumination, camera noise and nonlinear sensor responses among others. The challenge lies in detecting if the changes in pixels’ value are caused by a genuine object movement or not. An additional challenging aspect in motion detection is represented by moving cast shadows. The paradox arises because a moving object and its cast shadow share similar motion patterns. However, a moving cast shadow is not a moving object. In fact, a shadow represents a photometric illumination effect caused by the relative position of the object with respect to the light sources. Shadow detection methods are mainly divided in two domains depending on the application field. One normally consists of static images where shadows are casted by static objects, whereas the second one is referred to image sequences where shadows are casted by moving objects. For the first case, shadows can provide additional geometric and semantic cues about shape and position of its casting object as well as the localization of the light source. Although the previous information can be extracted from static images as well as video sequences, the main focus in the second area is usually change detection, scene matching or surveillance. In this context, a shadow can severely affect with the analysis and interpretation of the scene. The work done in the thesis is focused on the second case, thus it addresses the problem of detection and removal of moving cast shadows in video sequences in order to enhance the detection of moving object.

Abstract: Praxis test is a gesture-based diagnostic test which has been accepted as diagnostically indicative of cortical pathologies such as Alzheimer’s disease. Despite being simple, this test is oftentimes skipped by the clinicians. In this paper, we propose a novel framework to investigate the potential of static and dynamic upper-body gestures based on the Praxis test and their potential in a medical framework to automatize the test procedures for computer-assisted cognitive assessment of older adults.
In order to carry out gesture recognition as well as correctness assessment of the performances we have recollected a novel challenging RGB-D gesture video dataset recorded by Kinect v2, which contains 29 specific gestures suggested by clinicians and recorded from both experts and patients performing the gesture set. Moreover, we propose a framework to learn the dynamics of upper-body gestures, considering the videos as sequences of short-term clips of gestures. Our approach first uses body part detection to extract image patches surrounding the hands and then, by means of a fine-tuned convolutional neural network (CNN) model, it learns deep hand features which are then linked to a long short-term memory to capture the temporal dependencies between video frames.
We report the results of four developed methods using different modalities. The experiments show effectiveness of our deep learning based approach in gesture recognition and performance assessment tasks. Satisfaction of clinicians from the assessment reports indicates the impact of framework corresponding to the diagnosis.

Abstract: Purpose: Atheromatic plaque progression is affected, among others phenomena, by biomechanical, biochemical, and physiological factors. In this paper, the authors introduce a novel framework able to provide both morphological (vessel radius, plaque thickness, and type) and biomechanical (wall shear stress and Von Mises stress) indices of coronary arteries.Methods: First, the approach reconstructs the three-dimensional morphology of the vessel from intravascular ultrasound (IVUS) and Angiographic sequences, requiring minimal user interaction. Then, a computational pipeline allows to automatically assess fluid-dynamic and mechanical indices. Ten coronary arteries are analyzed illustrating the capabilities of the tool and confirming previous technical and clinical observations.Results: The relations between the arterial indices obtained by IVUS measurement and simulations have been quantitatively analyzed along the whole surface of the artery, extending the analysis of the coronary arteries shown in previous state of the art studies. Additionally, for the first time in the literature, the framework allows the computation of the membrane stresses using a simplified mechanical model of the arterial wall.Conclusions: Circumferentially (within a given frame), statistical analysis shows an inverse relation between the wall shear stress and the plaque thickness. At the global level (comparing a frame within the entire vessel), it is observed that heavy plaque accumulations are in general calcified and are located in the areas of the vessel having high wall shear stress. Finally, in their experiments the inverse proportionality between fluid and structural stresses is observed.