Abstract: A programme for evaluation of intestinal motility has been recently developed based on endoluminal image analysis using computer vision methodology and machine learning techniques. Our aim was to determine the effect of intestinal muscle inhibition on wall motion, dynamics of luminal content and transit in the small bowel. Fourteen healthy subjects ingested the endoscopic capsule (Pillcam, Given Imaging) in fasting conditions. Seven of them received glucagon (4.8 microg kg(-1) bolus followed by a 9.6 microg kg(-1) h(-1) infusion during 1 h) and in the other seven, fasting activity was recorded, as controls. This dose of glucagon has previously shown to inhibit both tonic and phasic intestinal motor activity. Endoluminal image and displacement was analyzed by means of a computer vision programme specifically developed for the evaluation of muscular activity (contractile and non-contractile patterns), intestinal contents, endoluminal motion and transit. Thirty-minute periods before, during and after glucagon infusion were analyzed and compared with equivalent periods in controls. No differences were found in the parameters measured during the baseline (pretest) periods when comparing glucagon and control experiments. During glucagon infusion, there was a significant reduction in contractile activity (0.2 +/- 0.1 vs 4.2 +/- 0.9 luminal closures per min, P < 0.05; 0.4 +/- 0.1 vs 3.4 +/- 1.2% of images with radial wrinkles, P < 0.05) and a significant reduction of endoluminal motion (82 +/- 9 vs 21 +/- 10% of static images, P < 0.05). Endoluminal image analysis, by means of computer vision and machine learning techniques, can reliably detect reduced intestinal muscle activity and motion.

Abstract: (Editorial for the Special Issue on Online pattern recognition and machine learning techniques)
In real life, visual learning is supposed to be a continuous process. This paradigm has found its way also in artificial vision systems. There is an increasing trend in pattern recognition represented by online learning approaches, which aims at continuously updating the data representation when new information arrives. Starting with a minimal dataset, the initial knowledge is expanded by incorporating incoming instances, which may have not been previously available or foreseen at the system’s design stage. An interesting characteristic of this strategy is that the train and test phases take place simultaneously. Given the increasing interest in this subject, the aim of this special issue is to be a landmark event in the development of online learning techniques and their applications with the hope that it will capture the interest of a wider audience and will attract even more researchers. We received 19 contributions, of which 9 have been accepted for publication, after having been subjected to usual peer review process.