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Eloi Puertas, Sergio Escalera, & Oriol Pujol. (2015). Generalized Multi-scale Stacked Sequential Learning for Multi-class Classification. PAA - Pattern Analysis and Applications, 18(2), 247–261.
Abstract: In many classification problems, neighbor data labels have inherent sequential relationships. Sequential learning algorithms take benefit of these relationships in order to improve generalization. In this paper, we revise the multi-scale sequential learning approach (MSSL) for applying it in the multi-class case (MMSSL). We introduce the error-correcting output codesframework in the MSSL classifiers and propose a formulation for calculating confidence maps from the margins of the base classifiers. In addition, we propose a MMSSL compression approach which reduces the number of features in the extended data set without a loss in performance. The proposed methods are tested on several databases, showing significant performance improvement compared to classical approaches.
Keywords: Stacked sequential learning; Multi-scale; Error-correct output codes (ECOC); Contextual classification
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Frederic Sampedro, & Sergio Escalera. (2015). Spatial codification of label predictions in Multi-scale Stacked Sequential Learning: A case study on multi-class medical volume segmentation. IETCV - IET Computer Vision, 9(3), 439–446.
Abstract: In this study, the authors propose the spatial codification of label predictions within the multi-scale stacked sequential learning (MSSL) framework, a successful learning scheme to deal with non-independent identically distributed data entries. After providing a motivation for this objective, they describe its theoretical framework based on the introduction of the blurred shape model as a smart descriptor to codify the spatial distribution of the predicted labels and define the new extended feature set for the second stacked classifier. They then particularise this scheme to be applied in volume segmentation applications. Finally, they test the implementation of the proposed framework in two medical volume segmentation datasets, obtaining significant performance improvements (with a 95% of confidence) in comparison to standard Adaboost classifier and classical MSSL approaches.
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Frederic Sampedro, Anna Domenech, Sergio Escalera, & Ignasi Carrio. (2015). Deriving global quantitative tumor response parameters from 18F-FDG PET-CT scans in patients with non-Hodgkins lymphoma. NMC - Nuclear Medicine Communications, 36(4), 328–333.
Abstract: OBJECTIVES:
The aim of the study was to address the need for quantifying the global cancer time evolution magnitude from a pair of time-consecutive positron emission tomography-computed tomography (PET-CT) scans. In particular, we focus on the computation of indicators using image-processing techniques that seek to model non-Hodgkin's lymphoma (NHL) progression or response severity.
MATERIALS AND METHODS:
A total of 89 pairs of time-consecutive PET-CT scans from NHL patients were stored in a nuclear medicine station for subsequent analysis. These were classified by a consensus of nuclear medicine physicians into progressions, partial responses, mixed responses, complete responses, and relapses. The cases of each group were ordered by magnitude following visual analysis. Thereafter, a set of quantitative indicators designed to model the cancer evolution magnitude within each group were computed using semiautomatic and automatic image-processing techniques. Performance evaluation of the proposed indicators was measured by a correlation analysis with the expert-based visual analysis.
RESULTS:
The set of proposed indicators achieved Pearson's correlation results in each group with respect to the expert-based visual analysis: 80.2% in progressions, 77.1% in partial response, 68.3% in mixed response, 88.5% in complete response, and 100% in relapse. In the progression and mixed response groups, the proposed indicators outperformed the common indicators used in clinical practice [changes in metabolic tumor volume, mean, maximum, peak standardized uptake value (SUV mean, SUV max, SUV peak), and total lesion glycolysis] by more than 40%.
CONCLUSION:
Computing global indicators of NHL response using PET-CT imaging techniques offers a strong correlation with the associated expert-based visual analysis, motivating the future incorporation of such quantitative and highly observer-independent indicators in oncological decision making or treatment response evaluation scenarios.
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Frederic Sampedro, Sergio Escalera, Anna Domenech, & Ignasi Carrio. (2015). Automatic Tumor Volume Segmentation in Whole-Body PET/CT Scans: A Supervised Learning Approach Source. JMIHI - Journal of Medical Imaging and Health Informatics, 5(2), 192–201.
Abstract: Whole-body 3D PET/CT tumoral volume segmentation provides relevant diagnostic and prognostic information in clinical oncology and nuclear medicine. Carrying out this procedure manually by a medical expert is time consuming and suffers from inter- and intra-observer variabilities. In this paper, a completely automatic approach to this task is presented. First, the problem is stated and described both in clinical and technological terms. Then, a novel supervised learning segmentation framework is introduced. The segmentation by learning approach is defined within a Cascade of Adaboost classifiers and a 3D contextual proposal of Multiscale Stacked Sequential Learning. Segmentation accuracy results on 200 Breast Cancer whole body PET/CT volumes show mean 49% sensitivity, 99.993% specificity and 39% Jaccard overlap Index, which represent good performance results both at the clinical and technological level.
Keywords: CONTEXTUAL CLASSIFICATION; PET/CT; SUPERVISED LEARNING; TUMOR SEGMENTATION; WHOLE BODY
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Meysam Madadi, Sergio Escalera, Jordi Gonzalez, Xavier Roca, & Felipe Lumbreras. (2015). Multi-part body segmentation based on depth maps for soft biometry analysis. PRL - Pattern Recognition Letters, 56, 14–21.
Abstract: This paper presents a novel method extracting biometric measures using depth sensors. Given a multi-part labeled training data, a new subject is aligned to the best model of the dataset, and soft biometrics such as lengths or circumference sizes of limbs and body are computed. The process is performed by training relevant pose clusters, defining a representative model, and fitting a 3D shape context descriptor within an iterative matching procedure. We show robust measures by applying orthogonal plates to body hull. We test our approach in a novel full-body RGB-Depth data set, showing accurate estimation of soft biometrics and better segmentation accuracy in comparison with random forest approach without requiring large training data.
Keywords: 3D shape context; 3D point cloud alignment; Depth maps; Human body segmentation; Soft biometry analysis
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